Gene description for SLC38A3
Gene name solute carrier family 38, member 3
Gene symbol SLC38A3
Other names/aliases G17
NAT1
SN1
SNAT3
Species Homo sapiens
 Database cross references - SLC38A3
ExoCarta ExoCarta_10991
Vesiclepedia VP_10991
Entrez Gene 10991
HGNC 18044
MIM 604437
UniProt Q99624  
 SLC38A3 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for SLC38A3
Molecular Function
    L-glutamine transmembrane transporter activity GO:0015186 IDA
    symporter activity GO:0015293 IEA
    antiporter activity GO:0015297 IEA
    L-histidine transmembrane transporter activity GO:0005290 IDA
    L-asparagine transmembrane transporter activity GO:0015182 IDA
    L-alanine transmembrane transporter activity GO:0015180 IDA
Biological Process
    L-alanine transport GO:0015808 IDA
    sodium ion transport GO:0006814 IEA
    ion transport GO:0006811 TAS
    amino acid transport GO:0006865 TAS
    histidine transport GO:0015817 IDA
    asparagine transport GO:0006867 IDA
    L-histidine transmembrane transport GO:0089709 IEA
    transmembrane transport GO:0055085 TAS
    glutamine transport GO:0006868 IDA
Subcellular Localization
    plasma membrane GO:0005886 TAS
    integral component of plasma membrane GO:0005887 ISS
 Experiment description of studies that identified SLC38A3 in exosomes
1
Experiment ID 126
MISEV standards
EV Biophysical techniques
GAPDH
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for SLC38A3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SETDB1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SLC38A3 is involved
PathwayEvidenceSource
Amino acid transport across the plasma membrane TAS Reactome





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