Gene description for NEDD4
Gene name neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
Gene symbol NEDD4
Other names/aliases NEDD4-1
RPF1
Species Homo sapiens
 Database cross references - NEDD4
ExoCarta ExoCarta_4734
Vesiclepedia VP_4734
Entrez Gene 4734
HGNC 7727
MIM 602278
UniProt P46934  
 NEDD4 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Colorectal cancer cells 19837982    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Prostate cancer cells 25844599    
 Gene ontology annotations for NEDD4
Molecular Function
    protein binding GO:0005515 IPI
    sodium channel inhibitor activity GO:0019871 IBA
    sodium channel inhibitor activity GO:0019871 IDA
    enzyme binding GO:0019899 IPI
    protein domain specific binding GO:0019904 IPI
    beta-2 adrenergic receptor binding GO:0031698 IDA
    ubiquitin binding GO:0043130 IDA
    phosphoserine residue binding GO:0050815 ISS
    phosphothreonine residue binding GO:0050816 ISS
    ubiquitin protein ligase activity GO:0061630 IBA
    ubiquitin protein ligase activity GO:0061630 IDA
    ubiquitin protein ligase activity GO:0061630 TAS
    RNA polymerase binding GO:0070063 IPI
    proline-rich region binding GO:0070064 IMP
    proline-rich region binding GO:0070064 IPI
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IMP
    ubiquitin-dependent protein catabolic process GO:0006511 IBA
    ubiquitin-dependent protein catabolic process GO:0006511 IDA
    ubiquitin-dependent protein catabolic process GO:0006511 IMP
    protein targeting to lysosome GO:0006622 IPI
    DNA damage response GO:0006974 IMP
    lysosomal transport GO:0007041 IDA
    neuromuscular junction development GO:0007528 IBA
    negative regulation of sodium ion transport GO:0010766 IDA
    regulation of macroautophagy GO:0016241 TAS
    protein ubiquitination GO:0016567 IDA
    protein ubiquitination GO:0016567 IDA
    negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948 ISS
    neuron projection development GO:0031175 IBA
    neuron projection development GO:0031175 IEP
    receptor internalization GO:0031623 IBA
    receptor internalization GO:0031623 IDA
    receptor catabolic process GO:0032801 IBA
    receptor catabolic process GO:0032801 IDA
    cellular response to UV GO:0034644 IMP
    regulation of monoatomic ion transmembrane transport GO:0034765 IDA
    regulation of membrane potential GO:0042391 IDA
    nuclear receptor-mediated glucocorticoid signaling pathway GO:0042921 IDA
    ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 IMP
    formation of structure involved in a symbiotic process GO:0044111 IMP
    innate immune response GO:0045087 IDA
    positive regulation of protein catabolic process GO:0045732 IDA
    viral budding GO:0046755 IMP
    positive regulation of nucleocytoplasmic transport GO:0046824 IDA
    regulation of dendrite morphogenesis GO:0048814 IBA
    regulation of dendrite morphogenesis GO:0048814 ISS
    regulation of synapse organization GO:0050807 IBA
    progesterone receptor signaling pathway GO:0050847 IDA
    response to calcium ion GO:0051592 TAS
    positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 IMP
    protein K63-linked ubiquitination GO:0070534 ISS
    regulation of potassium ion transmembrane transporter activity GO:1901016 IDA
    negative regulation of sodium ion transmembrane transporter activity GO:2000650 IDA
Subcellular Localization
    ubiquitin ligase complex GO:0000151 ISS
    chromatin GO:0000785 IDA
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    Golgi apparatus GO:0005794 IDA
    cytosol GO:0005829 ISS
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 IMP
    cell cortex GO:0005938 IDA
    apicolateral plasma membrane GO:0016327 TAS
    protein-containing complex GO:0032991 IDA
    dendritic spine GO:0043197 IBA
    perinuclear region of cytoplasm GO:0048471 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified NEDD4 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
6
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
 Protein-protein interactions for NEDD4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TUSC2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
2 ISG15 9636
Affinity Capture-Western Homo sapiens
3 ARHGEF2 9181
Co-fractionation Homo sapiens
4 SCN8A  
Affinity Capture-Western Homo sapiens
5 TTYH3 80727
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
6 SLC23A2 9962
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
7 FKBP15 23307
Co-fractionation Homo sapiens
8 Scnn1g  
Far Western Mus musculus
9 CALCOCO1 57658
Biochemical Activity Homo sapiens
10 UBC 7316
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
Co-crystal Structure Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
11 PARK7 11315
Affinity Capture-MS Homo sapiens
12 AMOTL1 154810
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
13 FGFR3 2261
Affinity Capture-Western Homo sapiens
14 APEX1 328
Affinity Capture-RNA Homo sapiens
15 MAP1LC3B 81631
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
16 MAP3K5 4217
Biochemical Activity Homo sapiens
17 ENO2 2026
Affinity Capture-MS Homo sapiens
18 FES 2242
Reconstituted Complex Homo sapiens
19 GRK4  
Reconstituted Complex Homo sapiens
20 SRC 6714
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
21 MAGED2 10916
Cross-Linking-MS (XL-MS) Homo sapiens
22 PTMS 5763
Affinity Capture-MS Homo sapiens
23 SCN5A 6331
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
24 Tnik  
Reconstituted Complex Rattus norvegicus
25 CAPZA1 829
Co-fractionation Homo sapiens
26 POLR2C 5432
Reconstituted Complex Homo sapiens
27 SMAD5 4090
Two-hybrid Homo sapiens
28 BTRC 8945
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
29 GUCD1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
30 WBP2 23558
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
31 SOD1 6647
Affinity Capture-MS Homo sapiens
32 RNF11 26994
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
33 ABCG1  
Affinity Capture-Western Homo sapiens
34 DYRK4  
Reconstituted Complex Homo sapiens
35 PMEPA1 56937
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
36 C11orf63  
Biochemical Activity Homo sapiens
37 Scnn1a  
Far Western Mus musculus
38 MAP3K2 10746
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
39 RAD51AP1  
Biochemical Activity Homo sapiens
40 WBP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 PDGFRB 5159
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
42 PLK2  
Biochemical Activity Homo sapiens
43 SERTAD1  
Reconstituted Complex Homo sapiens
44 AMPD2 271
Reconstituted Complex Homo sapiens
45 GABARAP 11337
Affinity Capture-MS Homo sapiens
46 NEDD4L 23327
Affinity Capture-MS Homo sapiens
47 CDK5R1  
Reconstituted Complex Homo sapiens
48 ANXA9  
Affinity Capture-Western Homo sapiens
49 ENO1 2023
Affinity Capture-MS Homo sapiens
50 SLC12A3 6559
Affinity Capture-Western Homo sapiens
51 GLIS3  
Affinity Capture-Western Homo sapiens
52 DDX39B 7919
Affinity Capture-MS Homo sapiens
53 MTMR4  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
54 YOD1  
Biochemical Activity Homo sapiens
55 TRPV6  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
56 TMEM52B 120939
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 SCNN1G  
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
58 FAM189B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 CTSK 1513
Affinity Capture-Western Homo sapiens
60 SLC5A7  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
61 CD274 29126
Affinity Capture-Western Homo sapiens
62 SUSD6 9766
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 AKT3  
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
64 YWHAZ 7534
Affinity Capture-MS Homo sapiens
65 ERBB4 2066
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
66 PLK1 5347
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
67 NHP2 55651
Reconstituted Complex Homo sapiens
68 WIBG 84305
Reconstituted Complex Homo sapiens
69 SAAL1 113174
Reconstituted Complex Homo sapiens
70 SPRY1 10252
Affinity Capture-Western Homo sapiens
71 N4BP3  
Affinity Capture-Western Homo sapiens
72 STMN1 3925
Affinity Capture-MS Homo sapiens
73 TCEANC  
Reconstituted Complex Homo sapiens
74 TMEM55A 55529
Affinity Capture-MS Homo sapiens
75 AKT1 207
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
76 GRK7  
Biochemical Activity Homo sapiens
77 PARP16 54956
Reconstituted Complex Homo sapiens
78 MLANA 2315
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
79 HSPE1 3336
Affinity Capture-MS Homo sapiens
80 NUDT21 11051
Reconstituted Complex Homo sapiens
81 GGA3 23163
Affinity Capture-Western Homo sapiens
82 DVL1 1855
Reconstituted Complex Homo sapiens
83 SKIL  
Affinity Capture-Western Homo sapiens
84 VOPP1  
Affinity Capture-MS Homo sapiens
85 CKB 1152
Affinity Capture-MS Homo sapiens
86 IL1B  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
87 IRS2 8660
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
88 SEPT9 10801
Reconstituted Complex Homo sapiens
89 SKP1 6500
Affinity Capture-Western Homo sapiens
90 BMPR1A 657
Reconstituted Complex Homo sapiens
91 TKT 7086
Affinity Capture-MS Homo sapiens
92 LATS1  
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
93 SGK2  
Biochemical Activity Homo sapiens
94 ANXA13 312
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
95 TBK1 29110
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
96 HNRNPL 3191
Reconstituted Complex Homo sapiens
97 POLA1  
Co-fractionation Homo sapiens
98 SMURF2 64750
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
99 ANXA2 302
Affinity Capture-MS Homo sapiens
100 PRKG2  
Reconstituted Complex Homo sapiens
101 PTCH1  
Affinity Capture-Western Homo sapiens
102 RBCK1  
Reconstituted Complex Homo sapiens
103 LRP3  
Affinity Capture-MS Homo sapiens
104 HMCES  
Reconstituted Complex Homo sapiens
105 ANP32A 8125
Affinity Capture-MS Homo sapiens
106 MPP5 64398
Affinity Capture-MS Homo sapiens
107 CYYR1  
Affinity Capture-MS Homo sapiens
108 GJA1 2697
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
109 PIP5K1C  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
110 NACA 4666
Affinity Capture-MS Homo sapiens
111 ADRB2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
112 THRAP3 9967
Reconstituted Complex Homo sapiens
113 HSP90AB1 3326
Co-fractionation Homo sapiens
114 GRB10 2887
Affinity Capture-Western Homo sapiens
115 DDIT4  
Affinity Capture-Western Homo sapiens
116 KIAA1598 57698
Reconstituted Complex Homo sapiens
117 S100A14 57402
Affinity Capture-MS Homo sapiens
118 TGFBR1 7046
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
119 PSIP1 11168
Affinity Capture-MS Homo sapiens
120 PGK1 5230
Affinity Capture-MS Homo sapiens
121 SUV420H2  
Affinity Capture-Western Homo sapiens
122 TNIK 23043
Reconstituted Complex Homo sapiens
123 MAP4K5 11183
Reconstituted Complex Homo sapiens
124 SYK 6850
Reconstituted Complex Homo sapiens
125 PRDX2 7001
Affinity Capture-MS Homo sapiens
126 TOM1 10043
Biochemical Activity Homo sapiens
127 SUN2 25777
Affinity Capture-MS Homo sapiens
128 YWHAH 7533
Affinity Capture-MS Homo sapiens
129 LDLRAD4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 CUL1 8454
Affinity Capture-Western Homo sapiens
131 POLR2M  
Reconstituted Complex Homo sapiens
132 EBAG9 9166
Reconstituted Complex Homo sapiens
133 YWHAB 7529
Affinity Capture-MS Homo sapiens
134 RUNX1  
Affinity Capture-Western Homo sapiens
135 PFN1 5216
Affinity Capture-MS Homo sapiens
136 GRIA1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
137 PRPF8 10594
Reconstituted Complex Homo sapiens
138 PLSCR1 5359
Affinity Capture-MS Homo sapiens
139 RBX1 9978
Affinity Capture-Western Homo sapiens
140 TTYH2 94015
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
141 CDK5 1020
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
142 STK31  
Biochemical Activity Homo sapiens
143 TMEM55B 90809
Affinity Capture-MS Homo sapiens
144 UBAP2L 9898
Reconstituted Complex Homo sapiens
145 LAPTM5 7805
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
146 RPS6KB1 6198
Biochemical Activity Homo sapiens
147 PPARG 5468
Affinity Capture-Western Homo sapiens
148 UBE2L3 7332
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
149 SLC9A1 6548
Affinity Capture-Western Homo sapiens
150 PTK2B 2185
Affinity Capture-Western Homo sapiens
151 TEAD2  
Reconstituted Complex Homo sapiens
152 LUC7L2 51631
Biochemical Activity Homo sapiens
153 SP140L  
Reconstituted Complex Homo sapiens
154 RAP2A 5911
Reconstituted Complex Homo sapiens
155 SLC38A3 10991
Affinity Capture-Western Homo sapiens
156 LAPTM4B  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
157 SLC22A6 9356
Affinity Capture-Western Homo sapiens
158 KHSRP 8570
Affinity Capture-RNA Homo sapiens
159 EIF6 3692
Affinity Capture-MS Homo sapiens
160 NDFIP2 54602
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
161 CAMK1D 57118
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
162 FGF12  
Reconstituted Complex Homo sapiens
163 POLR2E 5434
Reconstituted Complex Homo sapiens
164 TAF1B  
Reconstituted Complex Homo sapiens
165 CALR 811
Affinity Capture-MS Homo sapiens
166 PDIA3 2923
Affinity Capture-MS Homo sapiens
167 UBE2E1  
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
168 WEE1 7465
Reconstituted Complex Homo sapiens
169 SMAD1 4086
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
170 CDC25C  
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
171 BIRC6 57448
Biochemical Activity Homo sapiens
172 FGFR2 2263
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
173 TRIM44  
Biochemical Activity Homo sapiens
174 RAPGEF2 9693
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
175 SET 6418
Affinity Capture-MS Homo sapiens
176 EGFR 1956
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
177 BLMH 642
Affinity Capture-MS Homo sapiens
178 DDB1 1642
Co-fractionation Homo sapiens
179 IL2RB  
Affinity Capture-Western Homo sapiens
180 FKBP3 2287
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
181 SMAD6  
Affinity Capture-Western Homo sapiens
182 PGAM1 5223
Affinity Capture-MS Homo sapiens
183 HMGB1P1 10357
Affinity Capture-MS Homo sapiens
184 FBXL15  
Affinity Capture-Western Homo sapiens
185 TMEM51 55092
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 PRKCSH 5589
Affinity Capture-MS Homo sapiens
187 STK24 8428
Reconstituted Complex Homo sapiens
188 SGK1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
189 SMAD7  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
190 H3F3A 3020
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
191 PDCD6IP 10015
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
192 TRIM52  
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
193 FLT4  
Reconstituted Complex Homo sapiens
194 EZR 7430
Affinity Capture-MS Homo sapiens
195 TMEM255A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 AURKC  
Reconstituted Complex Homo sapiens
197 SQSTM1 8878
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
198 ILDR1 286676
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
199 MOB3A 126308
Reconstituted Complex Homo sapiens
200 STK26 51765
Reconstituted Complex Homo sapiens
201 SCAMP3 10067
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
202 SLC6A3  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
203 HNRNPK 3190
Reconstituted Complex Homo sapiens
204 PAX7  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
205 SLC11A2 4891
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
206 CALML5 51806
Affinity Capture-MS Homo sapiens
207 ERRFI1 54206
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
208 ANXA5 308
Affinity Capture-MS Homo sapiens
209 PRKX 5613
Biochemical Activity Homo sapiens
210 RFT1 91869
Reconstituted Complex Homo sapiens
211 GABARAPL1 23710
Affinity Capture-MS Homo sapiens
212 STK25 10494
Reconstituted Complex Homo sapiens
213 SLC22A8 9376
Affinity Capture-Western Homo sapiens
214 OCLN 100506658
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
215 MARCKS 4082
Affinity Capture-MS Homo sapiens
216 PTMA 5757
Affinity Capture-MS Homo sapiens
217 YWHAE 7531
Affinity Capture-MS Homo sapiens
218 GLP1R  
Affinity Capture-Western Homo sapiens
219 EPS15 2060
Biochemical Activity Homo sapiens
220 RPS6KA4 8986
Reconstituted Complex Homo sapiens
221 RET 5979
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
222 PEBP1 5037
Affinity Capture-MS Homo sapiens
223 CAPZB 832
Co-fractionation Homo sapiens
224 RUVBL1 8607
Reconstituted Complex Homo sapiens
225 RANBP10 57610
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
226 NOTCH1 4851
Affinity Capture-Western Homo sapiens
227 TNFRSF19  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
228 DMD 1756
Co-fractionation Homo sapiens
229 MAP3K3 4215
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
230 SPANXN3  
Biochemical Activity Homo sapiens
231 RPS3A 6189
Reconstituted Complex Homo sapiens
232 TCP11L1 55346
Reconstituted Complex Homo sapiens
233 PKN2 5586
Reconstituted Complex Homo sapiens
234 SULF1 23213
Reconstituted Complex Homo sapiens
235 THOC1 9984
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
236 RBM8A 9939
Affinity Capture-MS Homo sapiens
237 KIAA0196 9897
Co-fractionation Homo sapiens
238 MAP2 4133
Affinity Capture-Western Homo sapiens
239 MDH2 4191
Affinity Capture-MS Homo sapiens
240 NDFIP1 80762
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
241 SMO 6608
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
242 AMOTL2 51421
Affinity Capture-MS Homo sapiens
243 FOXA1  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
244 RTF1 23168
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
245 IGF1R 3480
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Co-localization Homo sapiens
246 ARHGEF1 9138
Co-fractionation Homo sapiens
247 AMOT 154796
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
248 MAPKAPK3 7867
Biochemical Activity Homo sapiens
249 SPDYA  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
250 FLT1 2321
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
251 NUMB 8650
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
252 NTRK1 4914
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
253 TPI1 7167
Affinity Capture-MS Homo sapiens
254 NSRP1  
Reconstituted Complex Homo sapiens
255 SMAD2 4087
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
256 HMGCL 3155
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
257 UBE2D3 7323
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
258 FYN 2534
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
259 LATS2 26524
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
260 TOM1L2 146691
Biochemical Activity Homo sapiens
261 HMGB2 3148
Affinity Capture-MS Homo sapiens
262 POLR2B 5431
Reconstituted Complex Homo sapiens
263 FGF21  
Reconstituted Complex Homo sapiens
264 RASGEF1A  
Biochemical Activity Homo sapiens
265 POLR3A 11128
Reconstituted Complex Homo sapiens
266 Ndfip1  
Affinity Capture-Western Mus musculus
267 NFKBIA  
Affinity Capture-Western Homo sapiens
268 FAM21A 387680
Co-fractionation Homo sapiens
269 S100A7 6278
Affinity Capture-MS Homo sapiens
270 ERMN 57471
Biochemical Activity Homo sapiens
271 YY1 7528
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
272 ABCB1 5243
Biochemical Activity Homo sapiens
273 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
274 DHX30 22907
Reconstituted Complex Homo sapiens
275 HNRNPUL1 11100
Reconstituted Complex Homo sapiens
276 POLR2A 5430
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
277 BASP1 10409
Affinity Capture-MS Homo sapiens
278 KIF26B  
Affinity Capture-Western Homo sapiens
279 NFE2  
Two-hybrid Homo sapiens
280 MGRN1 23295
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
281 LRRK1 79705
Affinity Capture-MS Homo sapiens
282 MRPL19 9801
Reconstituted Complex Homo sapiens
283 SAV1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
284 RAF1 5894
Reconstituted Complex Homo sapiens
285 FAIM2  
Affinity Capture-MS Homo sapiens
286 STK4 6789
Reconstituted Complex Homo sapiens
287 TMEM92  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
288 TPM3 7170
Affinity Capture-MS Homo sapiens
289 UBE2D1 7321
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
290 IFNG 3458
Affinity Capture-MS Homo sapiens
291 URI1  
Reconstituted Complex Homo sapiens
292 DDX3X 1654
Reconstituted Complex Homo sapiens
293 ASPSCR1 79058
Reconstituted Complex Homo sapiens
294 Scnn1b  
Far Western Mus musculus
295 GABARAPL2 11345
Affinity Capture-MS Homo sapiens
296 LITAF 9516
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
297 ABL1 25
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
298 KCNQ1  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
299 RASL11B  
Reconstituted Complex Homo sapiens
300 TMEM171  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
301 SFTPC  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
302 MIF 4282
Affinity Capture-MS Homo sapiens
303 FBXL18 80028
Affinity Capture-Western Homo sapiens
304 RPRD1B 58490
Affinity Capture-MS Homo sapiens
305 ERG  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
306 Snca  
Reconstituted Complex Mus musculus
Affinity Capture-Western Mus musculus
307 RAC1 5879
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
308 DIAPH1 1729
Reconstituted Complex Homo sapiens
309 PRR16  
Reconstituted Complex Homo sapiens
310 CAV1 857
Co-localization Homo sapiens
311 PRRG1 5638
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
312 SYT1 6857
Reconstituted Complex Homo sapiens
313 CUL5 8065
Affinity Capture-Western Homo sapiens
314 SIAH1  
Affinity Capture-Western Homo sapiens
315 RPSA 3921
Affinity Capture-Western Homo sapiens
316 ABL2  
Biochemical Activity Homo sapiens
317 ATPIF1 93974
Affinity Capture-MS Homo sapiens
318 CCNH  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
319 SCNN1A  
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
320 KIFC3 3801
Reconstituted Complex Homo sapiens
321 UBE2M 9040
Reconstituted Complex Homo sapiens
322 PHLPP1  
Affinity Capture-Western Homo sapiens
323 SIVA1  
Reconstituted Complex Homo sapiens
324 PRRG4  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
325 TSG101 7251
Affinity Capture-Western Homo sapiens
326 CALM1 801
Affinity Capture-MS Homo sapiens
327 RPS6KA3 6197
Biochemical Activity Homo sapiens
328 MARK2 2011
Biochemical Activity Homo sapiens
329 TSTA3 7264
Reconstituted Complex Homo sapiens
330 UBB  
Co-crystal Structure Bos taurus
331 PRDX3 10935
Affinity Capture-MS Homo sapiens
332 AQP2 359
Affinity Capture-Western Homo sapiens
333 KLF8  
Affinity Capture-Western Homo sapiens
334 ANP32B 10541
Affinity Capture-MS Homo sapiens
335 YES1 7525
Reconstituted Complex Homo sapiens
336 IMPDH2 3615
Co-fractionation Homo sapiens
337 HGS 9146
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
338 TMEM174  
Affinity Capture-MS Homo sapiens
339 YWHAG 7532
Affinity Capture-MS Homo sapiens
340 HMGA1 3159
Affinity Capture-MS Homo sapiens
341 DGCR2 9993
Affinity Capture-MS Homo sapiens
342 Rap2a  
Reconstituted Complex Rattus norvegicus
343 Usp2  
Affinity Capture-Western Mus musculus
344 MARK4  
Biochemical Activity Homo sapiens
345 CBLB 868
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
346 CSNK1D 1453
Affinity Capture-Western Homo sapiens
347 NEDD4 4734
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
348 LINC01198  
Protein-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
349 PPIB 5479
Affinity Capture-MS Homo sapiens
350 PDLIM7 9260
Affinity Capture-Western Homo sapiens
351 ARRDC1 92714
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
352 PSMD4 5710
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
353 IFITM3 10410
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
354 ERBB3 2065
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
355 HSP90B1 7184
Affinity Capture-MS Homo sapiens
356 MAPK8IP1 9479
Affinity Capture-MS Homo sapiens
357 UBE2I 7329
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
358 BRCA2 675
Protein-peptide Homo sapiens
359 HMGN1  
Affinity Capture-MS Homo sapiens
360 SMAD3 4088
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
361 SUMO2 6613
Affinity Capture-MS Homo sapiens
362 ARRDC3 57561
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
363 DDX54 79039
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
364 AP3B1 8546
Co-fractionation Homo sapiens
365 DNM2 1785
Co-fractionation Homo sapiens
366 KIAA1033 23325
Co-fractionation Homo sapiens
367 CAMKK2 10645
Reconstituted Complex Homo sapiens
368 ATP5B 506
Affinity Capture-MS Homo sapiens
369 CAD 790
Reconstituted Complex Homo sapiens
370 CPSF1 29894
Reconstituted Complex Homo sapiens
371 CLK3  
Reconstituted Complex Homo sapiens
372 PTEN 5728
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
373 DOCK7 85440
Co-fractionation Homo sapiens
374 ANKRD13D  
Biochemical Activity Homo sapiens
375 Pi4k2a  
Reconstituted Complex Mus musculus
376 AP1G2 8906
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
377 JUN 3725
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
378 MYCN  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
379 UBE2D2 7322
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
380 CAMK4 814
Reconstituted Complex Homo sapiens
381 DCUN1D1 54165
Biochemical Activity Homo sapiens
382 FABP5 2171
Affinity Capture-MS Homo sapiens
383 KCNAB2 8514
Reconstituted Complex Homo sapiens
384 MS4A10  
Affinity Capture-MS Homo sapiens
385 RPAP3 79657
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
386 EPRS 2058
Reconstituted Complex Homo sapiens
387 FGFR1 2260
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
388 ARID1A 8289
Reconstituted Complex Homo sapiens
389 CLTC 1213
Co-localization Homo sapiens
Co-fractionation Homo sapiens
390 Scnn1g  
Affinity Capture-Western Rattus norvegicus
391 TP73  
Affinity Capture-Western Homo sapiens
392 BAIAP2 10458
Biochemical Activity Homo sapiens
393 MDM2  
Protein-peptide Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
394 PRRG3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
395 GSDMD 79792
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
396 RPAP2  
Reconstituted Complex Homo sapiens
397 SNCA 6622
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
398 TNK2 10188
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
399 ARRB2 409
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
400 SPRY2 10253
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
401 CPSF6 11052
Reconstituted Complex Homo sapiens
402 YWHAH 282126
Reconstituted Complex Bos taurus
403 TBC1D7  
Reconstituted Complex Homo sapiens
404 PDIA4 9601
Affinity Capture-MS Homo sapiens
405 SMARCC1 6599
Reconstituted Complex Homo sapiens
406 IL2RG  
Affinity Capture-Western Homo sapiens
407 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
408 SMURF1 57154
Affinity Capture-MS Homo sapiens
409 SAMSN1  
Biochemical Activity Homo sapiens
410 GBA 2629
Biochemical Activity Homo sapiens
411 UBOX5  
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
412 SCNN1B 6338
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
413 RNF7  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
414 EPHA5 2044
Reconstituted Complex Homo sapiens
415 UBB 7314
Affinity Capture-MS Homo sapiens
416 BECN1 8678
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
417 TGM3 7053
Affinity Capture-MS Homo sapiens
418 ARRB1 408
Affinity Capture-Western Homo sapiens
419 HSF1  
Affinity Capture-Western Homo sapiens
420 SRSF7 6432
Reconstituted Complex Homo sapiens
421 KCNAB1  
Reconstituted Complex Homo sapiens
422 FAM189A2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
423 PRR7  
Affinity Capture-MS Homo sapiens
424 SRMS  
Reconstituted Complex Homo sapiens
425 HNRNPU 3192
Reconstituted Complex Homo sapiens
426 CFTR 1080
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
427 CUEDC1 404093
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
428 RAPGEF6 51735
Reconstituted Complex Homo sapiens
429 IRS1 3667
Reconstituted Complex Homo sapiens
430 CLIC2 1193
Biochemical Activity Homo sapiens
431 LAPTM4A 9741
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here