Gene description for HSP90AB1
Gene name heat shock protein 90kDa alpha (cytosolic), class B member 1
Gene symbol HSP90AB1
Other names/aliases D6S182
HSP84
HSP90B
HSPC2
HSPCB
Species Homo sapiens
 Database cross references - HSP90AB1
ExoCarta ExoCarta_3326
Vesiclepedia VP_3326
Entrez Gene 3326
HGNC 5258
MIM 140572
UniProt P08238  
 HSP90AB1 identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 30918259    
Breast cancer cells 30918259    
Breast cancer cells 30918259    
Cholangiocarcinoma cells 31054213    
Cholangiocarcinoma cells 31054213    
Cholangiocarcinoma cells 31054213    
Cholangiocarcinoma cells 31054213    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 22740476    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 22635005    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Mesothelioma cells 15111327    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Pluripotent stem cells 34108659    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
Thymus 23844026    
Urine 15326289    
Urine 21595033    
Urine 21595033    
Urine 21595033    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for HSP90AB1
Molecular Function
    RNA binding GO:0003723 HDA
    double-stranded RNA binding GO:0003725 IDA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IBA
    ATP binding GO:0005524 IDA
    ATP binding GO:0005524 IMP
    ATP hydrolysis activity GO:0016887 IBA
    ATP hydrolysis activity GO:0016887 TAS
    protein kinase regulator activity GO:0019887 IEA
    kinase binding GO:0019900 IPI
    protein kinase binding GO:0019901 IEA
    MHC class II protein complex binding GO:0023026 HDA
    nitric-oxide synthase regulator activity GO:0030235 ISS
    TPR domain binding GO:0030911 ISS
    heat shock protein binding GO:0031072 IPI
    ubiquitin protein ligase binding GO:0031625 IPI
    peptide binding GO:0042277 IPI
    identical protein binding GO:0042802 IPI
    protein homodimerization activity GO:0042803 IDA
    histone deacetylase binding GO:0042826 IPI
    ATP-dependent protein binding GO:0043008 IPI
    protein folding chaperone GO:0044183 ISS
    cadherin binding GO:0045296 HDA
    protein dimerization activity GO:0046983 IDA
    tau protein binding GO:0048156 NAS
    unfolded protein binding GO:0051082 IBA
    DNA polymerase binding GO:0070182 IPI
    protein phosphatase activator activity GO:0072542 IDA
    disordered domain specific binding GO:0097718 IPI
    ATP-dependent protein folding chaperone GO:0140662 IEA
    receptor ligand inhibitor activity GO:0141069 IDA
    histone methyltransferase binding GO:1990226 IPI
Biological Process
    placenta development GO:0001890 IEA
    protein folding GO:0006457 IBA
    response to unfolded protein GO:0006986 NAS
    telomere maintenance via telomerase GO:0007004 IDA
    virion attachment to host cell GO:0019062 IMP
    positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 IDA
    regulation of protein ubiquitination GO:0031396 IDA
    negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032435 IDA
    regulation of protein localization GO:0032880 ISS
    cellular response to heat GO:0034605 IBA
    negative regulation of apoptotic process GO:0043066 IEA
    positive regulation of nitric oxide biosynthetic process GO:0045429 ISS
    positive regulation of cell differentiation GO:0045597 IMP
    protein stabilization GO:0050821 IBA
    chaperone-mediated protein complex assembly GO:0051131 IDA
    regulation of cell cycle GO:0051726 IMP
    chaperone-mediated protein folding GO:0061077 ISS
    cellular response to interleukin-4 GO:0071353 IEA
    supramolecular fiber organization GO:0097435 IMP
    negative regulation of proteasomal protein catabolic process GO:1901799 ISS
    telomerase holoenzyme complex assembly GO:1905323 IDA
    positive regulation of protein localization to cell surface GO:2000010 IDA
Subcellular Localization
    extracellular region GO:0005576 IDA
    extracellular region GO:0005576 TAS
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IDA
    mitochondrion GO:0005739 HDA
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IBA
    COP9 signalosome GO:0008180 IDA
    cell surface GO:0009986 IEA
    membrane GO:0016020 HDA
    protein-containing complex GO:0032991 IBA
    protein-containing complex GO:0032991 IDA
    protein-containing complex GO:0032991 IMP
    aryl hydrocarbon receptor complex GO:0034751 IDA
    secretory granule lumen GO:0034774 TAS
    melanosome GO:0042470 IEA
    neuronal cell body GO:0043025 ISS
    dendritic growth cone GO:0044294 ISS
    axonal growth cone GO:0044295 ISS
    perinuclear region of cytoplasm GO:0048471 IBA
    perinuclear region of cytoplasm GO:0048471 ISS
    extracellular exosome GO:0070062 HDA
    protein folding chaperone complex GO:0101031 IMP
    dynein axonemal particle GO:0120293 ISS
    ficolin-1-rich granule lumen GO:1904813 TAS
    HSP90-CDC37 chaperone complex GO:1990565 IDA
 Experiment description of studies that identified HSP90AB1 in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
5
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 924
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|SDCBP|CD81|RAB35|LAMP2|FLOT1|TSG101|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 30918259    
Organism Homo sapiens
Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
Authors "Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC."
Journal name Nat Commun
Publication year 2019
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 924
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|SDCBP|CD81|RAB35|LAMP2|FLOT1|TSG101|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 30918259    
Organism Homo sapiens
Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
Authors "Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC."
Journal name Nat Commun
Publication year 2019
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 926
MISEV standards
✘ Biophysical techniques
✔
CD9|FLOT1|TSG101|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 30918259    
Organism Homo sapiens
Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
Authors "Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC."
Journal name Nat Commun
Publication year 2019
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
16
Experiment ID 927
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|SDCBP|CD81|RAB35|LAMP2|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 30918259    
Organism Homo sapiens
Experiment description Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
Authors "Im EJ, Lee CH, Moon PG, Rangaswamy GG, Lee B, Lee JM, Lee JC, Jee JG, Bae JS, Kwon TK, Kang KW, Jeong MS, Lee JE, Jung HS, Ro HJ, Jun S, Kang W, Seo SY, Cho YE, Song BJ, Baek MC."
Journal name Nat Commun
Publication year 2019
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 1223
MISEV standards
✔
EM
Biophysical techniques
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 31054213    
Organism Homo sapiens
Experiment description Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma
Authors "Weeraphan C, Phongdara A, Chaiyawat P, Diskul-Na-Ayudthaya P, Chokchaichamnankit D, Verathamjamras C, Netsirisawan P, Yingchutrakul Y, Roytrakul S, Champattanachai V, Svasti J, Srisomsap C."
Journal name Proteomics
Publication year 2019
Sample Cholangiocarcinoma cells
Sample name KKU-M213 - in-gel digestion
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 1224
MISEV standards
✔
EM
Biophysical techniques
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 31054213    
Organism Homo sapiens
Experiment description Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma
Authors "Weeraphan C, Phongdara A, Chaiyawat P, Diskul-Na-Ayudthaya P, Chokchaichamnankit D, Verathamjamras C, Netsirisawan P, Yingchutrakul Y, Roytrakul S, Champattanachai V, Svasti J, Srisomsap C."
Journal name Proteomics
Publication year 2019
Sample Cholangiocarcinoma cells
Sample name KKU-M213D5 - in-gel digestion
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 1225
MISEV standards
✔
EM
Biophysical techniques
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 31054213    
Organism Homo sapiens
Experiment description Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma
Authors "Weeraphan C, Phongdara A, Chaiyawat P, Diskul-Na-Ayudthaya P, Chokchaichamnankit D, Verathamjamras C, Netsirisawan P, Yingchutrakul Y, Roytrakul S, Champattanachai V, Svasti J, Srisomsap C."
Journal name Proteomics
Publication year 2019
Sample Cholangiocarcinoma cells
Sample name KKU-M213 - in-solution digestion
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 1226
MISEV standards
✔
EM
Biophysical techniques
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 31054213    
Organism Homo sapiens
Experiment description Phosphoproteome Profiling of Isogenic Cancer Cell-Derived Exosome Reveals HSP90 as a Potential Marker for Human Cholangiocarcinoma
Authors "Weeraphan C, Phongdara A, Chaiyawat P, Diskul-Na-Ayudthaya P, Chokchaichamnankit D, Verathamjamras C, Netsirisawan P, Yingchutrakul Y, Roytrakul S, Champattanachai V, Svasti J, Srisomsap C."
Journal name Proteomics
Publication year 2019
Sample Cholangiocarcinoma cells
Sample name KKU-M213D5 - in-solution digestion
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Sucrose density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
22
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
23
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
24
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
25
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
26
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
27
Experiment ID 201
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22740476    
Organism Homo sapiens
Experiment description Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.
Authors "Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ."
Journal name Electrophoresis
Publication year 2012
Sample Colorectal cancer cells
Sample name SW480
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
29
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
30
Experiment ID 285
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
31
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
32
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
33
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
37
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
42
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
43
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
44
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
45
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
46
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
47
Experiment ID 200
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|TSG101|Alix|GAPDH
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22635005    
Organism Homo sapiens
Experiment description Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Authors "Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, Garcia-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D."
Journal name Nat Med
Publication year 2012
Sample Melanoma cells
Sample name B16-F10
SK-MEL-202
SK-MEL035
SK-MEL-265
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
48
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
49
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
50
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
51
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
52
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
53
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
54
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
55
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
56
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
57
Experiment ID 25
MISEV standards
✔
IEM
Biophysical techniques
✔
HSP90|beta-tubulin
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15111327    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes secreted by human mesothelioma cells.
Authors "Hegmans JP, Bard MP, Hemmes A, Luider TM, Kleijmeer MJ, Prins JB, Zitvogel L, Burgers SA, Hoogsteden HC, Lambrecht BN."
Journal name AJP
Publication year 2004
Sample Mesothelioma cells
Sample name PMR-MM7
PMR-MM8
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
58
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
59
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
60
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
61
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
62
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
63
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
64
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
65
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
66
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
67
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
68
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
69
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
70
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
71
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
72
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
73
Experiment ID 137
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB6|CD10
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name PC3 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
74
Experiment ID 138
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
75
Experiment ID 139
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
76
Experiment ID 140
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
77
Experiment ID 141
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
78
Experiment ID 144
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
79
Experiment ID 145
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD10
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
80
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
81
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
82
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
83
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
84
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
85
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
86
Experiment ID 13
MISEV standards
✔
IEM
Biophysical techniques
✔
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors "Pisitkun T, Shen RF, Knepper MA"
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
87
Experiment ID 193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
88
Experiment ID 194
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
89
Experiment ID 195
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
90
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
91
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HSP90AB1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 REV1  
Affinity Capture-Western Homo sapiens
2 TSHZ1 10194
Cross-Linking-MS (XL-MS) Homo sapiens
3 ISG15 9636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 WDR6 11180
Co-fractionation Homo sapiens
5 UBL4A 8266
Affinity Capture-MS Homo sapiens
6 SHC1 6464
Affinity Capture-MS Homo sapiens
7 CDK7 1022
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 EXOSC3 51010
Co-fractionation Homo sapiens
9 MYLK4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 ERO1L 30001
Co-fractionation Homo sapiens
11 RIN3  
Affinity Capture-MS Homo sapiens
12 SKI 6497
Affinity Capture-MS Homo sapiens
13 DYNC1I2 1781
Proximity Label-MS Homo sapiens
14 CRK 1398
Affinity Capture-MS Homo sapiens
15 CAP1 10487
Co-fractionation Homo sapiens
16 UBA1 7317
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
17 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
18 LRRIQ1  
Cross-Linking-MS (XL-MS) Homo sapiens
19 SLC2A1 6513
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
20 C9orf78 51759
Affinity Capture-MS Homo sapiens
21 UBC 7316
Affinity Capture-MS Homo sapiens
22 CSNK2A1 1457
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
23 KPNA2 3838
Co-fractionation Homo sapiens
24 IGFBP4 3487
Affinity Capture-MS Homo sapiens
25 HSPA1A 3303
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
26 HDAC4  
Affinity Capture-MS Homo sapiens
27 HNRNPA0 10949
Cross-Linking-MS (XL-MS) Homo sapiens
28 FGFR3 2261
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
29 DARS 1615
Co-fractionation Homo sapiens
30 GTF2E2  
Affinity Capture-MS Homo sapiens
31 KIF23 9493
Affinity Capture-MS Homo sapiens
32 Tube1  
Affinity Capture-MS Mus musculus
33 CCAR2 57805
Co-fractionation Homo sapiens
34 METTL22  
Affinity Capture-MS Homo sapiens
35 SMYD3 64754
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 ERC1 23085
Cross-Linking-MS (XL-MS) Homo sapiens
37 SRC 6714
Affinity Capture-Luminescence Homo sapiens
38 PSMD12 5718
Co-fractionation Homo sapiens
39 HSPH1 10808
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
40 MARCH5  
Proximity Label-MS Homo sapiens
41 MAGED2 10916
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
42 EIF3E 3646
Cross-Linking-MS (XL-MS) Homo sapiens
43 DYNLL1 8655
Co-fractionation Homo sapiens
44 CHORDC1 26973
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 MECP2 4204
Affinity Capture-MS Homo sapiens
46 PPP6R3 55291
Co-fractionation Homo sapiens
47 GPS1 2873
Co-fractionation Homo sapiens
48 FKBPL  
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
49 SOD1 6647
Affinity Capture-Luminescence Homo sapiens
50 NEIL3  
Affinity Capture-MS Homo sapiens
51 KIF14 9928
Affinity Capture-MS Homo sapiens
52 EXOSC9 5393
Cross-Linking-MS (XL-MS) Homo sapiens
53 AGO2 27161
Co-fractionation Homo sapiens
54 UNK  
Affinity Capture-RNA Homo sapiens
55 CHMP4C 92421
Affinity Capture-MS Homo sapiens
56 AURKA 6790
Affinity Capture-MS Homo sapiens
57 HSP90AB4P 664618
Affinity Capture-MS Homo sapiens
58 MTCH2 23788
Affinity Capture-MS Homo sapiens
59 PKM 5315
Affinity Capture-MS Homo sapiens
60 RHOBTB2  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
61 USP11 8237
Affinity Capture-MS Homo sapiens
62 MEPCE 56257
Affinity Capture-MS Homo sapiens
63 MAPRE1 22919
Affinity Capture-MS Homo sapiens
64 TUFM 7284
Co-fractionation Homo sapiens
65 ACP2 53
Co-fractionation Homo sapiens
66 UBASH3B 84959
Affinity Capture-MS Homo sapiens
67 ESRRB  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
68 CDH1 999
Proximity Label-MS Homo sapiens
69 FYN 2534
Affinity Capture-MS Homo sapiens
70 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 MYH9 4627
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
72 GABARAP 11337
Cross-Linking-MS (XL-MS) Homo sapiens
73 ACTN4 81
Co-fractionation Homo sapiens
74 OGT 8473
Reconstituted Complex Homo sapiens
75 HLA-DRB5 3127
Affinity Capture-MS Homo sapiens
76 NOS2  
Affinity Capture-MS Homo sapiens
77 P4HB 5034
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
78 Calml3  
Affinity Capture-MS Mus musculus
79 ENO1 2023
Cross-Linking-MS (XL-MS) Homo sapiens
80 SNRPD1 6632
Co-fractionation Homo sapiens
81 CUL2 8453
Affinity Capture-MS Homo sapiens
82 TPM3 7170
Affinity Capture-MS Homo sapiens
83 SND1 27044
Co-fractionation Homo sapiens
84 VDAC2 7417
Co-fractionation Homo sapiens
85 CACYBP 27101
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
86 MGMT 4255
Affinity Capture-MS Homo sapiens
87 ACD  
Two-hybrid Homo sapiens
88 SSR4 6748
Co-fractionation Homo sapiens
89 SCARNA22  
Affinity Capture-RNA Homo sapiens
90 ANLN 54443
Affinity Capture-MS Homo sapiens
91 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
92 HSPA5 3309
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
93 HADHB 3032
Co-fractionation Homo sapiens
94 DMXL2  
Cross-Linking-MS (XL-MS) Homo sapiens
95 AHCYL1 10768
Cross-Linking-MS (XL-MS) Homo sapiens
96 KIF20A 10112
Affinity Capture-MS Homo sapiens
97 ANXA1 301
Protein-peptide Homo sapiens
98 NPM3 10360
Co-fractionation Homo sapiens
99 PRKCZ 5590
Affinity Capture-MS Homo sapiens
100 SLC25A1 6576
Affinity Capture-MS Homo sapiens
101 CUL3 8452
Affinity Capture-MS Homo sapiens
102 YWHAZ 7534
Co-fractionation Homo sapiens
103 FKBP8 23770
Affinity Capture-MS Homo sapiens
104 MYO19  
Affinity Capture-MS Homo sapiens
105 KLHDC4 54758
Co-fractionation Homo sapiens
106 ERP29 10961
Cross-Linking-MS (XL-MS) Homo sapiens
107 FN1 2335
Affinity Capture-MS Homo sapiens
108 FANCA  
Affinity Capture-Western Homo sapiens
Synthetic Lethality Homo sapiens
Affinity Capture-Luminescence Homo sapiens
109 HSP90AA4P 3323
Affinity Capture-MS Homo sapiens
110 PCBP1 5093
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
111 STAT1 6772
Two-hybrid Homo sapiens
112 SPEN 23013
Cross-Linking-MS (XL-MS) Homo sapiens
113 RPA3 6119
Proximity Label-MS Homo sapiens
114 FCHSD2  
Two-hybrid Homo sapiens
115 PSKH2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
116 MYO9B 4650
Cross-Linking-MS (XL-MS) Homo sapiens
117 HSP90AA2P 3324
Co-fractionation Homo sapiens
118 HSPA4 3308
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
119 AKT3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 SGTA 6449
Two-hybrid Homo sapiens
121 LY6E  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
122 TPP2 7174
Cross-Linking-MS (XL-MS) Homo sapiens
123 AKT1 207
Affinity Capture-Western Homo sapiens
124 Lrr1  
Affinity Capture-MS Mus musculus
125 PRKDC 5591
Affinity Capture-MS Homo sapiens
126 COPS2 9318
Co-fractionation Homo sapiens
127 RPS16 6217
Co-fractionation Homo sapiens
128 TNNT1  
Two-hybrid Homo sapiens
129 STUB1 10273
Biochemical Activity Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
130 DDX46 9879
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
131 BRAF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 HSPE1 3336
Co-fractionation Homo sapiens
133 GRK5 2869
Affinity Capture-MS Homo sapiens
134 FASN 2194
Affinity Capture-MS Homo sapiens
135 TUBGCP2 10844
Affinity Capture-MS Homo sapiens
136 GRB2 2885
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
137 PSAT1 29968
Affinity Capture-MS Homo sapiens
138 RUVBL2 10856
Affinity Capture-MS Homo sapiens
139 COPS7B 64708
Co-fractionation Homo sapiens
140 LRPPRC 10128
Co-fractionation Homo sapiens
141 CDC37 11140
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
142 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
143 CDK15  
Affinity Capture-MS Homo sapiens
144 DCTN2 10540
Co-fractionation Homo sapiens
145 BMPR1A 657
Affinity Capture-MS Homo sapiens
146 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
147 TAF1D  
Two-hybrid Homo sapiens
148 LATS1  
Affinity Capture-Western Homo sapiens
149 SGK2  
Affinity Capture-MS Homo sapiens
150 MAP2K2 5605
Affinity Capture-MS Homo sapiens
151 Tuba3a 22144
Affinity Capture-MS Mus musculus
152 GAPDH 2597
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
153 CDK4 1019
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 Cdc37 12539
Affinity Capture-MS Mus musculus
155 PRKCE 5581
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
156 POLA1  
Co-fractionation Homo sapiens
157 PTGES3 10728
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
158 SNW1 22938
Affinity Capture-MS Homo sapiens
159 POLR1D 51082
Affinity Capture-MS Homo sapiens
160 TET3  
Cross-Linking-MS (XL-MS) Homo sapiens
161 EDRF1  
Affinity Capture-MS Homo sapiens
162 CCAR1 55749
Co-fractionation Homo sapiens
163 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
164 LDHA 3939
Affinity Capture-MS Homo sapiens
165 HSP90AB2P 391634
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
166 PRKAA1 5562
Affinity Capture-MS Homo sapiens
167 IARS2 55699
Affinity Capture-MS Homo sapiens
168 SPRTN  
Affinity Capture-MS Homo sapiens
169 CLIP1 6249
Cross-Linking-MS (XL-MS) Homo sapiens
170 CDK3 1018
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 MAGEA3  
Affinity Capture-MS Homo sapiens
172 HSPA6 3310
Co-fractionation Homo sapiens
173 BTF3 689
Affinity Capture-MS Homo sapiens
174 VPRBP 9730
Co-fractionation Homo sapiens
175 CRYL1 51084
Affinity Capture-MS Homo sapiens
176 DBN1 1627
Affinity Capture-MS Homo sapiens
177 DTNA  
Affinity Capture-MS Homo sapiens
178 HSP90AB1 3326
Reconstituted Complex Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Reconstituted Complex Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
179 EIF4A1 1973
Co-fractionation Homo sapiens
180 CAND1 55832
Affinity Capture-MS Homo sapiens
181 SYVN1 84447
Affinity Capture-MS Homo sapiens
182 UNC45B  
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
183 GAN 8139
Affinity Capture-MS Homo sapiens
184 DNAJB6 10049
Affinity Capture-MS Homo sapiens
185 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
186 PSIP1 11168
Cross-Linking-MS (XL-MS) Homo sapiens
187 RPL32 6161
Co-fractionation Homo sapiens
188 METAP2 10988
Cross-Linking-MS (XL-MS) Homo sapiens
189 PGK1 5230
Affinity Capture-MS Homo sapiens
190 B3GNT2 10678
Affinity Capture-MS Homo sapiens
191 INSRR 3645
Affinity Capture-MS Homo sapiens
192 TUBB 203068
Co-fractionation Homo sapiens
193 DPYSL2 1808
Co-fractionation Homo sapiens
194 DDX24 57062
Two-hybrid Homo sapiens
195 COPS6 10980
Co-fractionation Homo sapiens
196 TLN1 7094
Co-fractionation Homo sapiens
197 RRP12 23223
Cross-Linking-MS (XL-MS) Homo sapiens
198 PRC1 9055
Affinity Capture-MS Homo sapiens
199 PRIM1  
Co-fractionation Homo sapiens
200 OBSL1 23363
Affinity Capture-MS Homo sapiens
201 TINF2  
Two-hybrid Homo sapiens
202 PLCG1 5335
Co-fractionation Homo sapiens
203 ADGRB3 577
Cross-Linking-MS (XL-MS) Homo sapiens
204 STIP1 10963
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
205 FANCD2  
Affinity Capture-MS Homo sapiens
206 DNAJC7 7266
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
207 VCAM1 7412
Affinity Capture-MS Homo sapiens
208 CUL1 8454
Affinity Capture-MS Homo sapiens
209 NPAS1  
Affinity Capture-MS Homo sapiens
210 PSAP 5660
Co-fractionation Homo sapiens
211 DNAH2 146754
Cross-Linking-MS (XL-MS) Homo sapiens
212 GSK3B 2932
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
213 TRIM8  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
214 YWHAB 7529
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
215 CCT2 10576
Reconstituted Complex Homo sapiens
216 GTF2I 2969
Co-fractionation Homo sapiens
217 PFN1 5216
Cross-Linking-MS (XL-MS) Homo sapiens
218 ATP6V1G1 9550
Cross-Linking-MS (XL-MS) Homo sapiens
219 PPP5C 5536
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
220 TTC4  
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
221 RPL4 6124
Co-fractionation Homo sapiens
222 CDK5 1020
Affinity Capture-MS Homo sapiens
223 MSX2  
Affinity Capture-MS Homo sapiens
224 PSMD14 10213
Affinity Capture-MS Homo sapiens
225 ACIN1 22985
Cross-Linking-MS (XL-MS) Homo sapiens
226 AHNAK 79026
Cross-Linking-MS (XL-MS) Homo sapiens
227 TUBA1C 84790
Affinity Capture-MS Homo sapiens
228 NELFE 7936
Affinity Capture-MS Homo sapiens
229 RLIM 51132
Affinity Capture-MS Homo sapiens
230 RAB2A 5862
Cross-Linking-MS (XL-MS) Homo sapiens
231 TTC9C 283237
Affinity Capture-MS Homo sapiens
232 Bag2  
Affinity Capture-MS Mus musculus
233 RPLP0 6175
Affinity Capture-MS Homo sapiens
234 RPLP0P6 220717
Co-fractionation Homo sapiens
235 GET4 51608
Co-fractionation Homo sapiens
236 Ksr1  
Affinity Capture-MS Mus musculus
237 CYLD  
Affinity Capture-MS Homo sapiens
238 Skp2  
Affinity Capture-MS Mus musculus
239 PPID  
Reconstituted Complex Bos taurus
240 FBXL4 26235
Affinity Capture-MS Homo sapiens
241 PTPN11 5781
Co-fractionation Homo sapiens
242 CAMKMT  
Affinity Capture-MS Homo sapiens
243 PSMA3 5684
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
244 CKAP5 9793
Co-fractionation Homo sapiens
245 COPS7A 50813
Co-fractionation Homo sapiens
246 Pank4  
Affinity Capture-MS Mus musculus
247 RPS2 6187
Co-fractionation Homo sapiens
248 XPO1 7514
Affinity Capture-MS Homo sapiens
249 RC3H2  
Affinity Capture-MS Homo sapiens
250 UBE2L6 9246
Affinity Capture-MS Homo sapiens
251 MEX3A  
Affinity Capture-RNA Homo sapiens
252 CALR 811
Co-fractionation Homo sapiens
253 PDIA3 2923
Co-fractionation Homo sapiens
254 ATP5F1 515
Co-fractionation Homo sapiens
255 TUBB4B 10383
Affinity Capture-MS Homo sapiens
256 EGFR 1956
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
257 NUP43 348995
Proximity Label-MS Homo sapiens
258 FUS 2521
Affinity Capture-MS Homo sapiens
259 HSP90AA5P 730211
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
260 HNRNPF 3185
Cross-Linking-MS (XL-MS) Homo sapiens
261 RIPK4  
Affinity Capture-MS Homo sapiens
262 LARS 51520
Affinity Capture-MS Homo sapiens
263 CDK2 1017
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
264 CEP250 11190
Affinity Capture-MS Homo sapiens
265 IFIT1 3434
Affinity Capture-MS Homo sapiens
266 HMGB3 3149
Cross-Linking-MS (XL-MS) Homo sapiens
267 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
268 CDKL4  
Affinity Capture-MS Homo sapiens
269 LMLN  
Cross-Linking-MS (XL-MS) Homo sapiens
270 MET 4233
Affinity Capture-Western Homo sapiens
271 CUL7 9820
Affinity Capture-MS Homo sapiens
272 DDRGK1 65992
Affinity Capture-MS Homo sapiens
273 XRCC3  
Affinity Capture-MS Homo sapiens
274 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
275 EIF3H 8667
Affinity Capture-MS Homo sapiens
276 DSP 1832
Co-fractionation Homo sapiens
277 HIST3H3 8290
Cross-Linking-MS (XL-MS) Homo sapiens
278 UBE3A 7337
Reconstituted Complex Homo sapiens
279 RAD21 5885
Affinity Capture-Western Homo sapiens
280 PRRC2A 7916
Cross-Linking-MS (XL-MS) Homo sapiens
281 TRAF2 7186
Co-localization Homo sapiens
Co-fractionation Homo sapiens
282 MYL6 4637
Co-fractionation Homo sapiens
283 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
284 FOLR1 2348
Affinity Capture-MS Homo sapiens
285 MKNK1  
Two-hybrid Homo sapiens
286 HDAC6 10013
Affinity Capture-MS Homo sapiens
287 KEAP1 9817
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
288 THOP1 7064
Cross-Linking-MS (XL-MS) Homo sapiens
289 AURKC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
290 CCDC117  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
291 RPS4X 6191
Affinity Capture-MS Homo sapiens
292 CENPF 1063
Cross-Linking-MS (XL-MS) Homo sapiens
293 FKBP4 2288
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
294 CDK6 1021
Affinity Capture-MS Homo sapiens
295 FKBP5 2289
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
296 MAP2K1 5604
Affinity Capture-MS Homo sapiens
297 UNC45A 55898
Reconstituted Complex Homo sapiens
298 MAPK6  
Two-hybrid Homo sapiens
299 RPS26 6231
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
300 KHDRBS2  
Affinity Capture-MS Homo sapiens
301 RPSA 3921
Affinity Capture-MS Homo sapiens
302 RPL7A 6130
Co-fractionation Homo sapiens
303 STK35  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
304 KRAS 3845
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
305 SLC33A1 9197
Affinity Capture-MS Homo sapiens
306 MYC  
Affinity Capture-MS Homo sapiens
307 IKBKB 3551
Co-fractionation Homo sapiens
Co-localization Homo sapiens
308 PRMT1 3276
Affinity Capture-MS Homo sapiens
309 CUL4A 8451
Affinity Capture-MS Homo sapiens
310 CC2D1A 54862
Cross-Linking-MS (XL-MS) Homo sapiens
311 TCP1 6950
Affinity Capture-MS Homo sapiens
312 HIST1H2BA 255626
Cross-Linking-MS (XL-MS) Homo sapiens
313 MVP 9961
Co-fractionation Homo sapiens
314 ATP6V1B2 526
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
315 MCM7 4176
Co-fractionation Homo sapiens
316 UBE2H 7328
Affinity Capture-MS Homo sapiens
317 SENP3 26168
Affinity Capture-MS Homo sapiens
318 INSIG1  
Affinity Capture-MS Homo sapiens
319 ANKK1  
Affinity Capture-MS Homo sapiens
320 YWHAE 7531
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
321 CD4 920
Affinity Capture-MS Homo sapiens
322 RPS6KA4 8986
Affinity Capture-MS Homo sapiens
323 SSB 6741
Co-fractionation Homo sapiens
324 EGLN1 54583
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
325 RPS6KB2  
Affinity Capture-MS Homo sapiens
326 ITGA6 3655
Cross-Linking-MS (XL-MS) Homo sapiens
327 TAF10 6881
Affinity Capture-MS Homo sapiens
328 AMHR2  
Affinity Capture-MS Homo sapiens
329 CAPZB 832
Affinity Capture-MS Homo sapiens
330 PTDSS2 81490
Affinity Capture-MS Homo sapiens
331 RPL10A 4736
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
332 MCM2 4171
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
333 IQGAP1 8826
Affinity Capture-MS Homo sapiens
334 MCM6 4175
Co-fractionation Homo sapiens
335 PSMC2 5701
Co-fractionation Homo sapiens
336 AASS  
Co-fractionation Homo sapiens
337 NUDC 10726
Co-fractionation Homo sapiens
338 UBE2Q1 55585
Co-fractionation Homo sapiens
339 ITGA4 3676
Affinity Capture-MS Homo sapiens
340 ATG7 10533
Co-fractionation Homo sapiens
341 ATG16L1 55054
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
342 RPS3A 6189
Affinity Capture-MS Homo sapiens
343 SPEF2 79925
Cross-Linking-MS (XL-MS) Homo sapiens
344 TUBA1A 7846
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
345 GPN1  
Affinity Capture-MS Homo sapiens
346 TFCP2 7024
Affinity Capture-MS Homo sapiens
347 YAF2  
Affinity Capture-MS Homo sapiens
348 HSPA8 3312
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
349 INSIG2  
Affinity Capture-MS Homo sapiens
350 BSG 682
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
351 ATP5A1 498
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
352 P4HA1 5033
Co-fractionation Homo sapiens
353 IPO7 10527
Co-fractionation Homo sapiens
354 NEB 4703
Cross-Linking-MS (XL-MS) Homo sapiens
355 FKBP6  
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
356 CUL4B 8450
Affinity Capture-MS Homo sapiens
357 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
358 IGF1R 3480
Affinity Capture-MS Homo sapiens
359 COPE 11316
Affinity Capture-MS Homo sapiens
360 JAK2 3717
Affinity Capture-Western Homo sapiens
361 CAST 831
Co-fractionation Homo sapiens
362 RPL5 6125
Affinity Capture-MS Homo sapiens
363 CHMP4B 128866
Affinity Capture-MS Homo sapiens
364 RPA2 6118
Proximity Label-MS Homo sapiens
365 NTRK1 4914
Affinity Capture-MS Homo sapiens
366 U2AF2 11338
Affinity Capture-MS Homo sapiens
367 SPAG17  
Cross-Linking-MS (XL-MS) Homo sapiens
368 ACTB 60
Co-fractionation Homo sapiens
369 COPS3 8533
Co-fractionation Homo sapiens
370 UBE2D3 7323
Biochemical Activity Homo sapiens
371 GNAI2 2771
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
372 LATS2 26524
Affinity Capture-Western Homo sapiens
373 HDAC5 10014
Affinity Capture-MS Homo sapiens
374 ACTG1 71
Affinity Capture-MS Homo sapiens
375 TRIM21 6737
Affinity Capture-MS Homo sapiens
376 TXLNA 200081
Co-fractionation Homo sapiens
377 SLX4  
Affinity Capture-MS Homo sapiens
378 KMT2A  
Cross-Linking-MS (XL-MS) Homo sapiens
379 METTL14  
Affinity Capture-MS Homo sapiens
380 TMOD4  
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
381 ECT2 1894
Affinity Capture-MS Homo sapiens
382 TRAF3IP1 26146
Affinity Capture-MS Homo sapiens
383 PPID 5481
Reconstituted Complex Homo sapiens
384 SIRPA 140885
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
385 HYPK 25764
Affinity Capture-MS Homo sapiens
386 RPL14 9045
Co-fractionation Homo sapiens
387 ENDOD1 23052
Cross-Linking-MS (XL-MS) Homo sapiens
388 NR3C1 2908
Affinity Capture-MS Homo sapiens
389 PSMA2 5683
Affinity Capture-MS Homo sapiens
390 NANS 54187
Affinity Capture-MS Homo sapiens
391 SYNCRIP 10492
Co-fractionation Homo sapiens
392 HSP90AB3P 3327
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
393 EIF3F 8665
Affinity Capture-MS Homo sapiens
394 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
395 METTL21B  
Affinity Capture-MS Homo sapiens
396 HNRNPUL1 11100
Co-fractionation Homo sapiens
397 MAP3K7  
Co-fractionation Homo sapiens
398 NCKIPSD 51517
Co-fractionation Homo sapiens
399 YWHAQ 10971
Co-fractionation Homo sapiens
400 MTOR 2475
Affinity Capture-MS Homo sapiens
401 TP63  
Affinity Capture-MS Homo sapiens
402 GBP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
403 PPP6C 5537
Affinity Capture-MS Homo sapiens
404 KIAA1671  
Cross-Linking-MS (XL-MS) Homo sapiens
405 KTN1 3895
Co-fractionation Homo sapiens
406 TXNDC5 81567
Co-fractionation Homo sapiens
407 HAX1  
Affinity Capture-MS Homo sapiens
408 HSPD1 3329
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
409 AARS 16
Affinity Capture-MS Homo sapiens
410 CHUK 1147
Affinity Capture-MS Homo sapiens
411 BCAP31 10134
Co-fractionation Homo sapiens
412 RBBP8  
Affinity Capture-MS Homo sapiens
413 HIF1A 3091
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
414 AHSA1 10598
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
415 SUGT1 10910
Affinity Capture-MS Homo sapiens
416 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
417 CYP17A1 1586
Two-hybrid Homo sapiens
418 SMC1A 8243
Cross-Linking-MS (XL-MS) Homo sapiens
419 GRK6 2870
Affinity Capture-MS Homo sapiens
420 JUP 3728
Affinity Capture-MS Homo sapiens
421 FBXL6  
Affinity Capture-MS Homo sapiens
422 RPL6 6128
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
423 AGO1  
Affinity Capture-MS Homo sapiens
424 MCM5 4174
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
425 GRHPR 9380
Affinity Capture-MS Homo sapiens
426 PRRC2C 23215
Co-fractionation Homo sapiens
427 ALDH1B1 219
Co-fractionation Homo sapiens
428 IKBKG 8517
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
429 CNPY2 10330
Cross-Linking-MS (XL-MS) Homo sapiens
430 HSPB1 3315
Two-hybrid Homo sapiens
431 CAP2 10486
Cross-Linking-MS (XL-MS) Homo sapiens
432 INPPL1 3636
Affinity Capture-MS Homo sapiens
433 MTHFD1 4522
Affinity Capture-MS Homo sapiens
434 TRIM25 7706
Co-fractionation Homo sapiens
435 EEF2 1938
Affinity Capture-MS Homo sapiens
436 UFL1 23376
Affinity Capture-MS Homo sapiens
437 CDK13 8621
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
438 PDIK1L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
439 LRRK2 120892
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
440 FLNA 2316
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
441 METTL3  
Affinity Capture-MS Homo sapiens
442 STK11 6794
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
443 SERBP1 26135
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
444 NFKBIB  
Co-fractionation Homo sapiens
445 ATXN3 4287
Affinity Capture-MS Homo sapiens
446 COPS4 51138
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
447 NOTCH1 4851
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
448 CDK11A 728642
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
449 CDKN2A 1029
Reconstituted Complex Homo sapiens
450 UBA52 7311
Co-fractionation Homo sapiens
451 CRBN  
Affinity Capture-MS Homo sapiens
452 ADRBK1 156
Affinity Capture-MS Homo sapiens
453 KMT2C 58508
Cross-Linking-MS (XL-MS) Homo sapiens
454 CCT3 7203
Cross-Linking-MS (XL-MS) Homo sapiens
455 DERL2 51009
Affinity Capture-MS Homo sapiens
456 POT1  
Two-hybrid Homo sapiens
457 CPOX 1371
Co-fractionation Homo sapiens
458 RPL30 6156
Co-fractionation Homo sapiens
459 PPIE 10450
Affinity Capture-MS Homo sapiens
460 PSMD11 5717
Co-fractionation Homo sapiens
461 TSSK6 83983
Affinity Capture-MS Homo sapiens
462 TNRC18  
Cross-Linking-MS (XL-MS) Homo sapiens
463 THOC2 57187
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
464 HSPA1L 3305
Co-fractionation Homo sapiens
465 VPS13A 23230
Cross-Linking-MS (XL-MS) Homo sapiens
466 ODF2 4957
Cross-Linking-MS (XL-MS) Homo sapiens
467 TAB1 10454
Co-fractionation Homo sapiens
468 CCT4 10575
Co-fractionation Homo sapiens
469 BASP1 10409
Co-fractionation Homo sapiens
470 HGH1 51236
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
471 SF3B2 10992
Co-fractionation Homo sapiens
472 GSK3A 2931
Two-hybrid Homo sapiens
473 KIAA1429 25962
Affinity Capture-MS Homo sapiens
474 RPS20 6224
Cross-Linking-MS (XL-MS) Homo sapiens
475 PPP1R12A 4659
Co-fractionation Homo sapiens
476 MARK2 2011
Co-fractionation Homo sapiens
477 TBCB 1155
Co-fractionation Homo sapiens
478 HLA-DRB3 3125
Affinity Capture-MS Homo sapiens
479 SHMT2 6472
Co-fractionation Homo sapiens
480 DIRAS2 54769
Affinity Capture-MS Homo sapiens
481 COPS5 10987
Co-fractionation Homo sapiens
482 AGO3  
Affinity Capture-MS Homo sapiens
483 MDH1 4190
Affinity Capture-MS Homo sapiens
484 YWHAG 7532
Co-fractionation Homo sapiens
485 DDOST 1650
Co-fractionation Homo sapiens
486 HADHA 3030
Co-fractionation Homo sapiens
487 ATP5C1 509
Co-fractionation Homo sapiens
488 SVIP 258010
Cross-Linking-MS (XL-MS) Homo sapiens
489 CHD2 1106
Cross-Linking-MS (XL-MS) Homo sapiens
490 EED  
Affinity Capture-MS Homo sapiens
491 WASL 8976
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
492 CDC73  
Affinity Capture-MS Homo sapiens
493 SFT2D2 375035
Cross-Linking-MS (XL-MS) Homo sapiens
494 PSMC6 5706
Co-fractionation Homo sapiens
495 MYCN  
Affinity Capture-MS Homo sapiens
496 ERBB2 2064
Affinity Capture-Western Homo sapiens
497 NEDD4 4734
Co-fractionation Homo sapiens
498 PSMC3 5702
Co-fractionation Homo sapiens
499 STOML2 30968
Co-fractionation Homo sapiens
500 PLA2G4A 5321
Affinity Capture-MS Homo sapiens
501 PNPLA5  
Affinity Capture-MS Homo sapiens
502 HLA-DRB4  
Affinity Capture-MS Homo sapiens
503 RB1CC1 9821
Affinity Capture-MS Homo sapiens
504 ERBB3 2065
Affinity Capture-MS Homo sapiens
505 HMGN2 3151
Cross-Linking-MS (XL-MS) Homo sapiens
506 HSP90B1 7184
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
507 CCT5 22948
Co-fractionation Homo sapiens
508 GALE 2582
Affinity Capture-MS Homo sapiens
509 HTT 3064
Affinity Capture-MS Homo sapiens
510 BRCA2 675
Affinity Capture-MS Homo sapiens
511 PFDN2 5202
Co-fractionation Homo sapiens
512 VCP 7415
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
513 SUMO2 6613
Reconstituted Complex Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
514 DICER1  
Co-fractionation Homo sapiens
515 C12orf10 60314
Affinity Capture-MS Homo sapiens
516 CRY2  
Affinity Capture-MS Homo sapiens
517 AIP 9049
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
518 ITK 3702
Affinity Capture-MS Homo sapiens
519 BTK 695
Affinity Capture-MS Homo sapiens
520 DNM2 1785
Cross-Linking-MS (XL-MS) Homo sapiens
521 CEP76  
Affinity Capture-MS Homo sapiens
522 UPF1 5976
Co-fractionation Homo sapiens
523 CLIC4 25932
Two-hybrid Homo sapiens
524 PRKACB 5567
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
525 ATP5B 506
Co-fractionation Homo sapiens
526 ST13 6767
Cross-Linking-MS (XL-MS) Homo sapiens
527 RPS6KA1 6195
Affinity Capture-MS Homo sapiens
528 SMARCC2 6601
Cross-Linking-MS (XL-MS) Homo sapiens
529 LRRC8A 56262
Cross-Linking-MS (XL-MS) Homo sapiens
530 YWHAH 7533
Co-fractionation Homo sapiens
531 BAG3 9531
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
532 TRDN 10345
Cross-Linking-MS (XL-MS) Homo sapiens
533 DDX59 83479
Affinity Capture-MS Homo sapiens
534 NUMA1 4926
Affinity Capture-MS Homo sapiens
535 ACTN1 87
Affinity Capture-MS Homo sapiens
536 IP6K2  
Affinity Capture-Western Homo sapiens
537 TOMM34 10953
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
538 HSF1  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
539 NR4A1  
Two-hybrid Homo sapiens
540 VPS4B 9525
Cross-Linking-MS (XL-MS) Homo sapiens
541 CDK9 1025
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
542 CLK3  
Affinity Capture-MS Homo sapiens
543 OTUD1 220213
Affinity Capture-MS Homo sapiens
544 CRISPLD2  
Affinity Capture-MS Homo sapiens
545 DOCK7 85440
Co-fractionation Homo sapiens
546 RPL35 11224
Cross-Linking-MS (XL-MS) Homo sapiens
547 UQCRC2 7385
Co-fractionation Homo sapiens
548 CTNNB1 1499
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
549 Bmpr1a  
Affinity Capture-MS Mus musculus
550 HCFC1 3054
Co-fractionation Homo sapiens
551 COPS8 10920
Co-fractionation Homo sapiens
552 ATP5I 521
Cross-Linking-MS (XL-MS) Homo sapiens
553 TXNRD1 7296
Co-fractionation Homo sapiens
554 RPL3 6122
Co-fractionation Homo sapiens
555 RPL7 6129
Affinity Capture-MS Homo sapiens
556 NXF1 10482
Affinity Capture-RNA Homo sapiens
557 AURKB 9212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
558 SLC35B2 347734
Affinity Capture-MS Homo sapiens
559 UGGT1 56886
Cross-Linking-MS (XL-MS) Homo sapiens
560 PRKACA 5566
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
561 AGO4  
Affinity Capture-MS Homo sapiens
562 MYO15A 51168
Cross-Linking-MS (XL-MS) Homo sapiens
563 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
564 FBXO6 26270
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
565 LAMA3 3909
Co-fractionation Homo sapiens
566 Get4  
Affinity Capture-MS Mus musculus
567 USP19 10869
Affinity Capture-MS Homo sapiens
568 RPAP3 79657
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
569 NFKB1 4790
Co-localization Homo sapiens
570 PSMB5 5693
Affinity Capture-MS Homo sapiens
571 ANK3  
Cross-Linking-MS (XL-MS) Homo sapiens
572 GOLGA8Q  
Cross-Linking-MS (XL-MS) Homo sapiens
573 MDM2  
Affinity Capture-MS Homo sapiens
574 CCDC8  
Affinity Capture-MS Homo sapiens
575 GSDMD 79792
Affinity Capture-MS Homo sapiens
576 SHKBP1  
Protein-RNA Homo sapiens
577 DHX15 1665
Cross-Linking-MS (XL-MS) Homo sapiens
578 ARRB2 409
Affinity Capture-MS Homo sapiens
579 SPTAN1 6709
Affinity Capture-MS Homo sapiens
580 PLEKHA6 22874
Cross-Linking-MS (XL-MS) Homo sapiens
581 PSMD1 5707
Affinity Capture-MS Homo sapiens
582 USP50  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
583 RRBP1 6238
Co-fractionation Homo sapiens
584 EFHC2  
Cross-Linking-MS (XL-MS) Homo sapiens
585 SVIL 6840
Co-fractionation Homo sapiens
586 RAD17  
Cross-Linking-MS (XL-MS) Homo sapiens
587 TUBG1 7283
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
588 HLA-DRA 3122
Affinity Capture-MS Homo sapiens
589 DNAJA2 10294
Co-fractionation Homo sapiens
590 ZNF746  
Affinity Capture-MS Homo sapiens
591 POLR1C 9533
Affinity Capture-MS Homo sapiens
592 LGALS3 3958
Affinity Capture-MS Homo sapiens
593 CUL5 8065
Affinity Capture-MS Homo sapiens
594 CDK18 5129
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
595 COL16A1 1307
Cross-Linking-MS (XL-MS) Homo sapiens
596 HDAC1 3065
Cross-Linking-MS (XL-MS) Homo sapiens
597 EPB41L2 2037
Co-fractionation Homo sapiens
598 SNRK  
Cross-Linking-MS (XL-MS) Homo sapiens
599 GIPC2 54810
Cross-Linking-MS (XL-MS) Homo sapiens
600 TXN 7295
Co-fractionation Homo sapiens
601 TERF1 7013
Two-hybrid Homo sapiens
602 RPS23 6228
Co-fractionation Homo sapiens
603 STK33  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
604 AIRE  
Affinity Capture-MS Homo sapiens
605 TRIM31  
Affinity Capture-MS Homo sapiens
606 PINK1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
607 MAP3K11 4296
Co-fractionation Homo sapiens
608 RPS6 6194
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
609 CDC37L1  
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
610 SRMS  
Affinity Capture-MS Homo sapiens
611 HNRNPU 3192
Co-fractionation Homo sapiens
612 C9orf72  
Affinity Capture-MS Homo sapiens
613 HLA-DRB1 3123
Affinity Capture-MS Homo sapiens
614 IVNS1ABP  
Affinity Capture-MS Homo sapiens
615 C5orf22  
Co-fractionation Homo sapiens
616 RPL17 6139
Co-fractionation Homo sapiens
617 ALDOA 226
Affinity Capture-MS Homo sapiens
618 CDC5L 988
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which HSP90AB1 is involved
PathwayEvidenceSource
Aryl hydrocarbon receptor signalling TAS Reactome
Assembly and release of respiratory syncytial virus (RSV) virions TAS Reactome
Attenuation phase TAS Reactome
Autophagy IEA Reactome
Axon guidance TAS Reactome
Bacterial Infection Pathways TAS Reactome
Biological oxidations TAS Reactome
Cell Cycle TAS Reactome
Cell Cycle, Mitotic TAS Reactome
Cell recruitment (pro-inflammatory response) TAS Reactome
Cellular response to heat stress TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Chaperone Mediated Autophagy IEA Reactome
DDX58/IFIH1-mediated induction of interferon-alpha/beta TAS Reactome
Developmental Biology TAS Reactome
Disease TAS Reactome
ESR-mediated signaling TAS Reactome
Estrogen-dependent gene expression TAS Reactome
Fcgamma receptor (FCGR) dependent phagocytosis TAS Reactome
G2/M Transition TAS Reactome
HSF1 activation TAS Reactome
HSF1-dependent transactivation TAS Reactome
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand TAS Reactome
Immune System TAS Reactome
Infectious disease TAS Reactome
Inflammasomes TAS Reactome
Innate Immune System TAS Reactome
Leishmania infection TAS Reactome
Metabolism TAS Reactome
Mitotic G2-G2/M phases TAS Reactome
Nervous system development TAS Reactome
Neutrophil degranulation TAS Reactome
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways TAS Reactome
Parasitic Infection Pathways TAS Reactome
Phase I - Functionalization of compounds TAS Reactome
Potential therapeutics for SARS TAS Reactome
Purinergic signaling in leishmaniasis infection TAS Reactome
Regulation of actin dynamics for phagocytic cup formation TAS Reactome
Respiratory syncytial virus (RSV) genome replication, transcription and translation TAS Reactome
Respiratory syncytial virus genome replication TAS Reactome
Respiratory Syncytial Virus Infection Pathway TAS Reactome
RHO GTPase cycle TAS Reactome
RHOBTB GTPase Cycle TAS Reactome
RHOBTB2 GTPase cycle TAS Reactome
SARS-CoV Infections TAS Reactome
SARS-CoV-2 activates/modulates innate and adaptive immune responses TAS Reactome
SARS-CoV-2 Infection TAS Reactome
SARS-CoV-2-host interactions TAS Reactome
Sema3A PAK dependent Axon repulsion TAS Reactome
Semaphorin interactions TAS Reactome
Signal Transduction TAS Reactome
Signaling by Nuclear Receptors TAS Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
The NLRP3 inflammasome TAS Reactome
The role of GTSE1 in G2/M progression after G2 checkpoint TAS Reactome
Uptake and actions of bacterial toxins TAS Reactome
Uptake and function of diphtheria toxin TAS Reactome
Viral Infection Pathways TAS Reactome





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