Gene description for ECT2
Gene name	epithelial cell transforming 2
Gene symbol	ECT2
Other names/aliases	ARHGEF31
Species	Homo sapiens
Database cross references - ECT2
ExoCarta	ExoCarta_1894
Entrez Gene	1894
HGNC	3155
MIM	600586
UniProt	Q9H8V3
ECT2 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for ECT2

Molecular Function     protein homodimerization activity GO:0042803 IDA     GTPase activator activity GO:0005096 IMP     Rho GTPase binding GO:0017048 IEA     protein binding GO:0005515 IPI     Rho guanyl-nucleotide exchange factor activity GO:0005089 IDA     signal transducer activity GO:0004871 IMP Biological Process     cellular response to ionizing radiation GO:0071479 IDA     cellular response to hydrogen peroxide GO:0070301 IDA     cellular response to calcium ion GO:0071277 IDA     cytokinesis GO:0000910 IMP     positive regulation of apoptotic process GO:0043065 TAS     apoptotic signaling pathway GO:0097190 TAS     positive regulation of neuron differentiation GO:0045666 ISS     positive regulation of protein import into nucleus GO:0042307 ISS     activation of GTPase activity GO:0090630 IMP     bicellular tight junction assembly GO:0070830 IMP     protein homooligomerization GO:0051260 IDA     activation of protein kinase activity GO:0032147 IDA     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 IMP     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     protein transport GO:0015031 IEA     regulation of protein kinase activity GO:0045859 IDA     small GTPase mediated signal transduction GO:0007264 TAS     positive regulation of cytokinesis GO:0032467 IMP     regulation of attachment of spindle microtubules to kinetochore GO:0051988 IMP     positive regulation of GTPase activity GO:0043547 IMP     cell morphogenesis GO:0000902 IEA     regulation of small GTPase mediated signal transduction GO:0051056 TAS Subcellular Localization     cell-cell junction GO:0005911 IDA     cleavage furrow GO:0032154 IDA     cytosol GO:0005829 TAS     nucleus GO:0005634 IDA     bicellular tight junction GO:0005923 IDA     cytoplasm GO:0005737 IDA     intracellular membrane-bounded organelle GO:0043231 IDA     midbody GO:0030496 IDA     nuclear membrane GO:0031965 IDA     centralspindlin complex GO:0097149 IDA     mitotic spindle GO:0072686 IDA