Gene description for ECT2
Gene name	epithelial cell transforming 2
Gene symbol	ECT2
Other names/aliases	ARHGEF31
Species	Homo sapiens
Database cross references - ECT2
ExoCarta	ExoCarta_1894
Vesiclepedia	VP_1894
Entrez Gene	1894
HGNC	3155
MIM	600586
UniProt	Q9H8V3
ECT2 identified in sEVs derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for ECT2

Molecular Function     guanyl-nucleotide exchange factor activity GO:0005085 IBA     guanyl-nucleotide exchange factor activity GO:0005085 IDA     guanyl-nucleotide exchange factor activity GO:0005085 TAS     GTPase activator activity GO:0005096 IMP     protein binding GO:0005515 IPI     small GTPase binding GO:0031267 IEA     protein homodimerization activity GO:0042803 IDA Biological Process     mitotic cytokinesis GO:0000281 IBA     mitotic cytokinesis GO:0000281 IMP     cell morphogenesis GO:0000902 IEA     nervous system development GO:0007399 IBA     protein transport GO:0015031 IEA     cell differentiation GO:0030154 IEA     activation of protein kinase activity GO:0032147 IDA     positive regulation of cytokinesis GO:0032467 IDA     positive regulation of cytokinesis GO:0032467 IMP     intracellular signal transduction GO:0035556 IEA     positive regulation of protein import into nucleus GO:0042307 ISS     positive regulation of apoptotic process GO:0043065 IDA     positive regulation of canonical NF-kappaB signal transduction GO:0043123 HMP     positive regulation of GTPase activity GO:0043547 IDA     positive regulation of GTPase activity GO:0043547 IMP     positive regulation of neuron differentiation GO:0045666 ISS     regulation of protein kinase activity GO:0045859 IDA     regulation of small GTPase mediated signal transduction GO:0051056 TAS     protein homooligomerization GO:0051260 IDA     regulation of attachment of spindle microtubules to kinetochore GO:0051988 IMP     cellular response to hydrogen peroxide GO:0070301 IDA     bicellular tight junction assembly GO:0070830 IMP     cellular response to calcium ion GO:0071277 IDA     cellular response to ionizing radiation GO:0071479 IDA     activation of GTPase activity GO:0090630 IDA     activation of GTPase activity GO:0090630 IMP     positive regulation of mitotic cytokinetic process GO:1903438 IMP     regulation of cytokinesis, actomyosin contractile ring assembly GO:2000431 IEA Subcellular Localization     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 IDA     cytoplasm GO:0005737 IDA     centrosome GO:0005813 IEA     cytosol GO:0005829 IDA     cytosol GO:0005829 TAS     cell-cell junction GO:0005911 IDA     bicellular tight junction GO:0005923 IDA     cell cortex GO:0005938 IBA     nuclear body GO:0016604 IDA     midbody GO:0030496 IDA     cleavage furrow GO:0032154 IDA     mitotic spindle GO:0072686 IDA     centralspindlin complex GO:0097149 IDA