Gene description for INA
Gene name internexin neuronal intermediate filament protein, alpha
Gene symbol INA
Other names/aliases NEF5
NF-66
TXBP-1
Species Homo sapiens
 Database cross references - INA
ExoCarta ExoCarta_9118
Vesiclepedia VP_9118
Entrez Gene 9118
HGNC 6057
MIM 605338
UniProt Q16352  
 INA identified in exosomes derived from the following tissue/cell type
Liver cancer cells 25265333    
 Gene ontology annotations for INA
Molecular Function
    structural constituent of cytoskeleton GO:0005200 TAS
Biological Process
    cell differentiation GO:0030154 IEA
    substantia nigra development GO:0021762 IEP
    neurofilament cytoskeleton organization GO:0060052 IEA
Subcellular Localization
    extracellular space GO:0005615 IDA
    intermediate filament cytoskeleton GO:0045111 IDA
    neurofilament GO:0005883 IEA
    nuclear membrane GO:0031965 IDA
    cytoplasmic ribonucleoprotein granule GO:0036464 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified INA in exosomes
1
Experiment ID 267
MISEV standards
EV Biophysical techniques
TSG101|Alix
EV Enriched markers
CANX|HSP90B1
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh‑7 Cells Using SILAC Labeling and LC−MS/MS
Authors Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J
Journal name J Proteome Res
Publication year 2014
Sample Liver cancer cells
Sample name Huh-7 - Transfected with HBx plasmids
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for INA
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which INA is involved
No pathways found





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