Gene description for TFCP2
Gene name transcription factor CP2
Gene symbol TFCP2
Other names/aliases LBP1C
LSF
LSF1D
SEF
TFCP2C
Species Homo sapiens
 Database cross references - TFCP2
ExoCarta ExoCarta_7024
Vesiclepedia VP_7024
Entrez Gene 7024
HGNC 11748
MIM 189889
UniProt Q12800  
 TFCP2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for TFCP2
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 ISA
    cis-regulatory region sequence-specific DNA binding GO:0000987 IDA
    DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 IBA
    DNA binding GO:0003677 TAS
    DNA-binding transcription factor activity GO:0003700 TAS
    protein binding GO:0005515 IPI
    transcription factor binding GO:0008134 IPI
    sequence-specific double-stranded DNA binding GO:1990837 IDA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IDA
    mRNA transcription by RNA polymerase II GO:0042789 IDA
    positive regulation of transcription by RNA polymerase II GO:0045944 IBA
    positive regulation of transcription by RNA polymerase II GO:0045944 IDA
Subcellular Localization
    chromatin GO:0000785 ISA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    cytosol GO:0005829 IDA
    protein-containing complex GO:0032991 IDA
    protein-containing complex GO:0032991 IMP
 Experiment description of studies that identified TFCP2 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TFCP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF3A 8661
Affinity Capture-MS Homo sapiens
2 NPEPPS 9520
Affinity Capture-MS Homo sapiens
3 WDR6 11180
Affinity Capture-MS Homo sapiens
4 HDAC2 3066
Reconstituted Complex Homo sapiens
5 LDHB 3945
Affinity Capture-MS Homo sapiens
6 PKM 5315
Affinity Capture-MS Homo sapiens
7 PSMA4 5685
Affinity Capture-MS Homo sapiens
8 CA1 759
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
9 TPM2 7169
Affinity Capture-MS Homo sapiens
10 GLB1 2720
Affinity Capture-MS Homo sapiens
11 DDX17 10521
Affinity Capture-MS Homo sapiens
12 ACTC1 70
Affinity Capture-MS Homo sapiens
13 UBA1 7317
Affinity Capture-MS Homo sapiens
14 TUBB8 347688
Affinity Capture-MS Homo sapiens
15 PRKDC 5591
Affinity Capture-MS Homo sapiens
16 AMOTL1 154810
Affinity Capture-MS Homo sapiens
17 CKB 1152
Affinity Capture-MS Homo sapiens
18 DPM1 8813
Affinity Capture-MS Homo sapiens
19 HSPH1 10808
Affinity Capture-MS Homo sapiens
20 ABCD3 5825
Affinity Capture-MS Homo sapiens
21 TLK1  
Two-hybrid Homo sapiens
22 RPS9 6203
Affinity Capture-MS Homo sapiens
23 LAMTOR3 8649
Affinity Capture-MS Homo sapiens
24 GNAZ 2781
Affinity Capture-MS Homo sapiens
25 SLC25A31 83447
Affinity Capture-MS Homo sapiens
26 FOXP3  
Affinity Capture-MS Homo sapiens
27 EEF1A1 1915
Affinity Capture-MS Homo sapiens
28 MYL6 4637
Affinity Capture-MS Homo sapiens
29 AURKA 6790
Affinity Capture-MS Homo sapiens
30 NEDD9 4739
Two-hybrid Homo sapiens
31 TCP1 6950
Affinity Capture-MS Homo sapiens
32 CAPZA1 829
Affinity Capture-MS Homo sapiens
33 KRT6A 3853
Affinity Capture-MS Homo sapiens
34 CLTCL1 8218
Affinity Capture-MS Homo sapiens
35 TUFM 7284
Affinity Capture-MS Homo sapiens
36 PABPC1 26986
Affinity Capture-MS Homo sapiens
37 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 MYH9 4627
Affinity Capture-MS Homo sapiens
39 RPL31 6160
Affinity Capture-MS Homo sapiens
40 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
41 BICD2 23299
Proximity Label-MS Homo sapiens
42 YWHAQ 10971
Affinity Capture-MS Homo sapiens
43 ENO1 2023
Affinity Capture-MS Homo sapiens
44 MAPK8 5599
Biochemical Activity Homo sapiens
45 FLOT2 2319
Affinity Capture-MS Homo sapiens
46 POLR3GL  
Two-hybrid Homo sapiens
47 SLC25A5 292
Affinity Capture-MS Homo sapiens
48 HSPA5 3309
Affinity Capture-MS Homo sapiens
49 PKLR 5313
Affinity Capture-MS Homo sapiens
50 RBM39 9584
Affinity Capture-MS Homo sapiens
51 HADHB 3032
Affinity Capture-MS Homo sapiens
52 HADHA 3030
Affinity Capture-MS Homo sapiens
53 AGPAT1 10554
Affinity Capture-MS Homo sapiens
54 STMN2  
Two-hybrid Homo sapiens
55 LRRC59 55379
Affinity Capture-MS Homo sapiens
56 LMNB1 4001
Affinity Capture-MS Homo sapiens
57 POTEI 653269
Affinity Capture-MS Homo sapiens
58 MYH14 79784
Affinity Capture-MS Homo sapiens
59 TUBAL3 79861
Affinity Capture-MS Homo sapiens
60 ACTBL2 345651
Affinity Capture-MS Homo sapiens
61 NOM1  
Reconstituted Complex Homo sapiens
62 EEF1B2 1933
Affinity Capture-MS Homo sapiens
63 MYO1C 4641
Affinity Capture-MS Homo sapiens
64 KRT14 3861
Affinity Capture-MS Homo sapiens
65 GLO1 2739
Affinity Capture-MS Homo sapiens
66 KRT15 3866
Affinity Capture-MS Homo sapiens
67 GPANK1  
Two-hybrid Homo sapiens
68 HSP90AA4P 3323
Affinity Capture-MS Homo sapiens
69 GNAS 2778
Affinity Capture-MS Homo sapiens
70 HSPA1A 3303
Affinity Capture-MS Homo sapiens
71 HSPA4 3308
Affinity Capture-MS Homo sapiens
72 GNA14 9630
Affinity Capture-MS Homo sapiens
73 CTNNA1 1495
Affinity Capture-MS Homo sapiens
74 KRT19 3880
Affinity Capture-MS Homo sapiens
75 PABPC3 5042
Affinity Capture-MS Homo sapiens
76 ZCCHC12  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
77 RPS16 6217
Affinity Capture-MS Homo sapiens
78 YBX1 4904
Affinity Capture-MS Homo sapiens
79 FASN 2194
Affinity Capture-MS Homo sapiens
80 RPL6 6128
Affinity Capture-MS Homo sapiens
81 PCMT1 5110
Affinity Capture-MS Homo sapiens
82 TUBA4B 80086
Affinity Capture-MS Homo sapiens
83 TKT 7086
Affinity Capture-MS Homo sapiens
84 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
85 TARS 6897
Affinity Capture-MS Homo sapiens
86 IP6K1 9807
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 OAT 4942
Affinity Capture-MS Homo sapiens
88 DYNC1H1 1778
Affinity Capture-MS Homo sapiens
89 NFE4  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
90 RPS24 6229
Affinity Capture-MS Homo sapiens
91 GAPDH 2597
Affinity Capture-MS Homo sapiens
92 PAPSS1 9061
Affinity Capture-MS Homo sapiens
93 HNRNPA1L2 144983
Affinity Capture-MS Homo sapiens
94 RPL23A 6147
Affinity Capture-MS Homo sapiens
95 NHSL2  
Two-hybrid Homo sapiens
96 FANCL 55120
Two-hybrid Homo sapiens
97 RAB20 55647
Affinity Capture-MS Homo sapiens
98 GNAI3 2773
Affinity Capture-MS Homo sapiens
99 LDHA 3939
Affinity Capture-MS Homo sapiens
100 TUBA8 51807
Affinity Capture-MS Homo sapiens
101 KRT6B 3854
Affinity Capture-MS Homo sapiens
102 HSPA6 3310
Affinity Capture-MS Homo sapiens
103 RPS17 6218
Affinity Capture-MS Homo sapiens
104 BTF3 689
Affinity Capture-MS Homo sapiens
105 ALB 213
Affinity Capture-MS Homo sapiens
106 GFAP 2670
Affinity Capture-MS Homo sapiens
107 HSP90AB1 3326
Affinity Capture-MS Homo sapiens
108 EIF4A1 1973
Affinity Capture-MS Homo sapiens
109 ARID3B  
Affinity Capture-MS Homo sapiens
110 RPS3 6188
Affinity Capture-MS Homo sapiens
111 TDRD1  
Two-hybrid Homo sapiens
112 RPS18 6222
Affinity Capture-MS Homo sapiens
113 POTEE 445582
Affinity Capture-MS Homo sapiens
114 PGK1 5230
Affinity Capture-MS Homo sapiens
115 MYO3B 140469
Affinity Capture-MS Homo sapiens
116 HSPA2 3306
Affinity Capture-MS Homo sapiens
117 FOXN1  
Affinity Capture-MS Homo sapiens
118 PITPNM1 9600
Two-hybrid Homo sapiens
119 MAPK14 1432
Biochemical Activity Homo sapiens
120 PRDX2 7001
Affinity Capture-MS Homo sapiens
121 STIP1 10963
Affinity Capture-MS Homo sapiens
122 HSPA7 3311
Affinity Capture-MS Homo sapiens
123 TUBA3C 7278
Affinity Capture-MS Homo sapiens
124 HIST1H2AA 221613
Affinity Capture-MS Homo sapiens
125 MOB3C  
Two-hybrid Homo sapiens
126 WIF1 11197
Affinity Capture-MS Homo sapiens
127 PHF1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
128 SDCBP 6386
Two-hybrid Homo sapiens
129 AMOT  
Affinity Capture-MS Homo sapiens
130 KRT25 147183
Affinity Capture-MS Homo sapiens
131 ATAD3A 55210
Affinity Capture-MS Homo sapiens
132 YWHAB 7529
Affinity Capture-MS Homo sapiens
133 CCT2 10576
Affinity Capture-MS Homo sapiens
134 GTF2I 2969
Affinity Capture-MS Homo sapiens
135 ACTA2 59
Affinity Capture-MS Homo sapiens
136 SLC1A5 6510
Affinity Capture-MS Homo sapiens
137 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 DDX21 9188
Affinity Capture-MS Homo sapiens
139 MYO1A 4640
Affinity Capture-MS Homo sapiens
140 RPL4 6124
Affinity Capture-MS Homo sapiens
141 RAI14 26064
Affinity Capture-MS Homo sapiens
142 GNAI1 2770
Affinity Capture-MS Homo sapiens
143 LYN 4067
Affinity Capture-MS Homo sapiens
144 BAG6 7917
Two-hybrid Homo sapiens
145 EPHA10  
Two-hybrid Homo sapiens
146 UBP1 7342
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 TUBA1C 84790
Affinity Capture-MS Homo sapiens
148 AIM2  
Affinity Capture-MS Homo sapiens
149 FOXC2  
Affinity Capture-MS Homo sapiens
150 TEAD2  
Affinity Capture-MS Homo sapiens
151 NCL 4691
Affinity Capture-MS Homo sapiens
152 RPLP0 6175
Affinity Capture-MS Homo sapiens
153 RPLP0P6 220717
Affinity Capture-MS Homo sapiens
154 HNRNPD 3184
Affinity Capture-MS Homo sapiens
155 TUBB 203068
Affinity Capture-MS Homo sapiens
156 DNAJC27  
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
157 KHSRP 8570
Affinity Capture-MS Homo sapiens
158 RPN2 6185
Affinity Capture-MS Homo sapiens
159 AIFM1 9131
Affinity Capture-MS Homo sapiens
160 RPS2 6187
Affinity Capture-MS Homo sapiens
161 XPO1 7514
Affinity Capture-MS Homo sapiens
162 PSMD5 5711
Two-hybrid Homo sapiens
163 IRAK1BP1 134728
Two-hybrid Homo sapiens
164 TUBB4B 10383
Affinity Capture-MS Homo sapiens
165 AKR7A2 8574
Affinity Capture-MS Homo sapiens
166 MORF4L1  
Two-hybrid Homo sapiens
167 SPTBN1 6711
Affinity Capture-MS Homo sapiens
168 TPM1 7168
Affinity Capture-MS Homo sapiens
169 FAM64A 54478
Two-hybrid Homo sapiens
170 TMOD3 29766
Affinity Capture-MS Homo sapiens
171 EEF1A2 1917
Affinity Capture-MS Homo sapiens
172 PGAM1 5223
Affinity Capture-MS Homo sapiens
173 MPRIP 23164
Affinity Capture-MS Homo sapiens
174 PHGDH 26227
Affinity Capture-MS Homo sapiens
175 DSP 1832
Affinity Capture-MS Homo sapiens
176 RPL13 6137
Affinity Capture-MS Homo sapiens
177 PARP1 142
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
178 TP53 7157
Affinity Capture-MS Homo sapiens
179 C19orf73  
Two-hybrid Homo sapiens
180 RPS4X 6191
Affinity Capture-MS Homo sapiens
181 RPS5 6193
Affinity Capture-MS Homo sapiens
182 HNRNPK 3190
Affinity Capture-MS Homo sapiens
183 RPS26 6231
Affinity Capture-MS Homo sapiens
184 RPSA 3921
Affinity Capture-MS Homo sapiens
185 RPL7A 6130
Affinity Capture-MS Homo sapiens
186 TMEM109 79073
Affinity Capture-MS Homo sapiens
187 ANXA5 308
Affinity Capture-MS Homo sapiens
188 IRS4 8471
Affinity Capture-MS Homo sapiens
189 KRT76 51350
Affinity Capture-MS Homo sapiens
190 MVP 9961
Two-hybrid Homo sapiens
191 MAP1LC3C  
Affinity Capture-MS Homo sapiens
192 CCDC94  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
193 HNRNPC 3183
Affinity Capture-MS Homo sapiens
194 RAB1A 5861
Affinity Capture-MS Homo sapiens
195 EEF1G 1937
Affinity Capture-MS Homo sapiens
196 FAM43A  
Affinity Capture-MS Homo sapiens
197 RPS19 6223
Affinity Capture-MS Homo sapiens
198 PRMT6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
199 HNRNPCL1 343069
Affinity Capture-MS Homo sapiens
200 HNRNPR 10236
Affinity Capture-MS Homo sapiens
201 APBB1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
202 ANKRD29  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
203 GNG12 55970
Affinity Capture-MS Homo sapiens
204 RPL10A 4736
Affinity Capture-MS Homo sapiens
205 RUVBL1 8607
Affinity Capture-MS Homo sapiens
206 INA 9118
Affinity Capture-MS Homo sapiens
207 TFCP2 7024
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 DPH1  
Two-hybrid Homo sapiens
209 Cebpb  
Affinity Capture-Western Rattus norvegicus
210 HSPA8 3312
Affinity Capture-MS Homo sapiens
211 FOXP1 27086
Affinity Capture-MS Homo sapiens
212 MDH2 4191
Affinity Capture-MS Homo sapiens
213 NF2 4771
Affinity Capture-MS Homo sapiens
214 RPL27 6155
Affinity Capture-MS Homo sapiens
215 ATAD3B 83858
Affinity Capture-MS Homo sapiens
216 DLD 1738
Affinity Capture-MS Homo sapiens
217 ATP5A1 498
Affinity Capture-MS Homo sapiens
218 FOXC1  
Affinity Capture-MS Homo sapiens
219 DPYSL4 10570
Affinity Capture-MS Homo sapiens
220 PRPH 5630
Affinity Capture-MS Homo sapiens
221 RPS10 6204
Affinity Capture-MS Homo sapiens
222 TCEA2  
Two-hybrid Homo sapiens
223 MARS 4141
Affinity Capture-MS Homo sapiens
224 TUBA1A 7846
Affinity Capture-MS Homo sapiens
225 TUBA1B 10376
Affinity Capture-MS Homo sapiens
226 RAN 5901
Affinity Capture-MS Homo sapiens
227 TPI1 7167
Affinity Capture-MS Homo sapiens
228 SIN3A  
Reconstituted Complex Homo sapiens
229 RPL36 25873
Affinity Capture-MS Homo sapiens