Experiment description of studies that identified HNRNPCL1 in exosomes

1 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for HNRNPCL1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 CRBN   Affinity Capture-MS Homo sapiens 2 RALY 22913 Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens 3 C20orf202   Two-hybrid Homo sapiens 4 RALYL 138046 Two-hybrid Homo sapiens 5 HNRNPC 3183 Affinity Capture-MS Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens 6 BPIFA1 51297 Affinity Capture-MS Homo sapiens 7 NCBP1 4686 Affinity Capture-MS Homo sapiens 8 DGCR14   Affinity Capture-MS Homo sapiens 9 KPNA3 3839 Affinity Capture-MS Homo sapiens 10 CCNH   Affinity Capture-MS Homo sapiens 11 Hnrnpc 15381 Two-hybrid Mus musculus 12 HMCES   Affinity Capture-MS Homo sapiens 13 RBM22 55696 Affinity Capture-MS Homo sapiens 14 BCLAF1 9774 Affinity Capture-MS Homo sapiens 15 BUB1   Affinity Capture-MS Homo sapiens 16 PPIE 10450 Affinity Capture-MS Homo sapiens 17 SRPK2 6733 Affinity Capture-MS Homo sapiens 18 RPA2 6118 Affinity Capture-MS Homo sapiens 19 PRPF38A 84950 Affinity Capture-MS Homo sapiens 20 QKI 9444 Affinity Capture-MS Homo sapiens 21 EBNA-LP   Affinity Capture-MS 22 LARP1B 55132 Affinity Capture-MS Homo sapiens 23 RBMXL1   Affinity Capture-MS Homo sapiens 24 NGRN   Affinity Capture-MS Homo sapiens 25 PRKACG   Affinity Capture-MS Homo sapiens 26 XPA   Affinity Capture-MS Homo sapiens 27 ZFR 51663 Affinity Capture-MS Homo sapiens 28 PUM2 23369 Affinity Capture-MS Homo sapiens 29 HNRNPCL1 343069 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 30 CAND1 55832 Affinity Capture-MS Homo sapiens 31 AQR 9716 Affinity Capture-MS Homo sapiens 32 PRR5   Affinity Capture-MS Homo sapiens 33 GNG10 2790 Affinity Capture-MS Homo sapiens 34 MSI1   Affinity Capture-MS Homo sapiens 35 HNRNPUL2 221092 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens 36 WTAP 9589 Affinity Capture-MS Homo sapiens 37 CRNKL1 51340 Affinity Capture-MS Homo sapiens 38 PRDX3 10935 Affinity Capture-MS Homo sapiens 39 NOLC1 9221 Co-fractionation Homo sapiens 40 PABPC4L 132430 Affinity Capture-MS Homo sapiens 41 ISY1 57461 Affinity Capture-MS Homo sapiens 42 HEY1   Affinity Capture-MS Homo sapiens 43 COPS5 10987 Affinity Capture-MS Homo sapiens 44 YARS2   Affinity Capture-MS Homo sapiens 45 SUPV3L1 6832 Affinity Capture-MS Homo sapiens 46 HMHA1 23526 Co-fractionation Homo sapiens 47 C17orf85   Affinity Capture-MS Homo sapiens 48 PTCD1 26024 Affinity Capture-MS Homo sapiens 49 STAU2 27067 Affinity Capture-MS Homo sapiens 50 PRKRA 8575 Affinity Capture-MS Homo sapiens 51 CLK2 1196 Affinity Capture-MS Homo sapiens 52 MECP2 4204 Affinity Capture-MS Homo sapiens 53 CUL1 8454 Affinity Capture-MS Homo sapiens 54 TFCP2 7024 Affinity Capture-MS Homo sapiens 55 ARIH2 10425 Affinity Capture-MS Homo sapiens 56 ASF1A 25842 Proximity Label-MS Homo sapiens 57 SREK1 140890 Affinity Capture-MS Homo sapiens 58 FAM120A 23196 Affinity Capture-MS Homo sapiens 59 MTERF3   Affinity Capture-MS Homo sapiens 60 LARP4B 23185 Affinity Capture-MS Homo sapiens 61 CHMP4C 92421 Affinity Capture-MS Homo sapiens 62 MRPL13   Affinity Capture-MS Homo sapiens 63 EIF2AK2 5610 Affinity Capture-MS Homo sapiens 64 SCAF1   Affinity Capture-MS Homo sapiens 65 CUL4B 8450 Affinity Capture-MS Homo sapiens 66 PARK2   Affinity Capture-MS Homo sapiens 67 PHAX   Affinity Capture-MS Homo sapiens 68 SHMT1 6470 Affinity Capture-MS Homo sapiens 69 TRA2A 29896 Affinity Capture-MS Homo sapiens 70 PPIP5K2 23262 Cross-Linking-MS (XL-MS) Homo sapiens 71 ZCCHC3   Affinity Capture-MS Homo sapiens 72 KPNA4 3840 Affinity Capture-MS Homo sapiens 73 UBE2I 7329 Two-hybrid Homo sapiens 74 FAM118B   Affinity Capture-MS Homo sapiens 75 YAP1 10413 Affinity Capture-MS Homo sapiens 76 MKRN2 23609 Affinity Capture-MS Homo sapiens 77 HIST1H1C 3006 Affinity Capture-MS Homo sapiens 78 ZC3H14   Affinity Capture-MS Homo sapiens 79 PLXNA2 5362 Cross-Linking-MS (XL-MS) Homo sapiens 80 ZFC3H1 196441 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 81 RAD54L2   Two-hybrid Homo sapiens 82 UPF1 5976 Affinity Capture-MS Homo sapiens 83 Tipin   Affinity Capture-MS Mus musculus 84 CCDC12   Affinity Capture-MS Homo sapiens 85 LARP1 23367 Affinity Capture-MS Homo sapiens 86 ELAVL2 1993 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 87 PAIP2B   Affinity Capture-MS Homo sapiens 88 HNRNPD 3184 Affinity Capture-MS Homo sapiens 89 RPS19 6223 Cross-Linking-MS (XL-MS) Homo sapiens 90 TRPV5   Affinity Capture-MS Homo sapiens 91 FANCD2   Affinity Capture-MS Homo sapiens 92 C11orf57   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 93 CEP135   Affinity Capture-MS Homo sapiens 94 CLK3   Affinity Capture-MS Homo sapiens 95 ST8SIA2   Affinity Capture-MS Homo sapiens 96 CUL3 8452 Affinity Capture-MS Homo sapiens 97 XAB2 56949 Affinity Capture-MS Homo sapiens 98 DNAJC17   Affinity Capture-MS Homo sapiens 99 ZC3H11A   Affinity Capture-MS Homo sapiens 100 TFG 10342 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 101 ZC3H10   Affinity Capture-MS Homo sapiens 102 YTHDC1   Affinity Capture-MS Homo sapiens 103 FASN 2194 Cross-Linking-MS (XL-MS) Homo sapiens 104 PRKACA 5566 Affinity Capture-MS Homo sapiens 105 DND1   Affinity Capture-MS Homo sapiens 106 RPA3 6119 Affinity Capture-MS Homo sapiens 107 RELT   Affinity Capture-MS Homo sapiens 108 PABPC5 140886 Affinity Capture-MS Homo sapiens 109 TP63   Affinity Capture-MS Homo sapiens 110 HIST1H1A 3024 Affinity Capture-MS Homo sapiens 111 SRSF10 10772 Affinity Capture-MS Homo sapiens 112 FYTTD1   Affinity Capture-MS Homo sapiens 113 RAC2 5880 Affinity Capture-MS Homo sapiens 114 PAIP1 10605 Affinity Capture-MS Homo sapiens 115 YBX1 4904 Affinity Capture-MS Homo sapiens 116 HNRNPCL2 440563 Affinity Capture-MS Homo sapiens Two-hybrid Homo sapiens 117 MKRN1 23608 Affinity Capture-MS Homo sapiens 118 HIST1H2BO 8348 Affinity Capture-MS Homo sapiens 119 CUL2 8453 Affinity Capture-MS Homo sapiens 120 WWOX 51741 Affinity Capture-MS Homo sapiens 121 Ube2i   Two-hybrid Mus musculus 122 MCM5 4174 Affinity Capture-MS Homo sapiens 123 PPHLN1   Affinity Capture-MS Homo sapiens 124 RPA1 6117 Affinity Capture-MS Homo sapiens 125 CUL5 8065 Affinity Capture-MS Homo sapiens 126 THRAP3 9967 Affinity Capture-MS Homo sapiens 127 CDC40   Affinity Capture-MS Homo sapiens 128 CWF19L2   Affinity Capture-MS Homo sapiens 129 HIST1H2BD 3017 Affinity Capture-MS Homo sapiens 130 PRR3   Affinity Capture-MS Homo sapiens 131 PPIG 9360 Affinity Capture-MS Homo sapiens 132 MOV10 4343 Affinity Capture-MS Homo sapiens 133 PLXNA4 91584 Cross-Linking-MS (XL-MS) Homo sapiens 134 NHLRC1   Affinity Capture-MS Homo sapiens 135 METTL3   Affinity Capture-MS Homo sapiens 136 SNW1 22938 Affinity Capture-MS Homo sapiens 137 RPL36AL 6166 Affinity Capture-MS Homo sapiens 138 VDAC3 7419 Cross-Linking-MS (XL-MS) Homo sapiens 139 SNRPA1 6627 Affinity Capture-MS Homo sapiens 140 CASC3   Affinity Capture-MS Homo sapiens 141 Cdc26   Affinity Capture-MS Mus musculus View the network

Pathways in which HNRNPCL1 is involved

No pathways found