Gene description for PTCD1
Gene name pentatricopeptide repeat domain 1
Gene symbol PTCD1
Other names/aliases -
Species Homo sapiens
 Database cross references - PTCD1
ExoCarta ExoCarta_26024
Entrez Gene 26024
HGNC 22198
MIM 614774
UniProt O75127  
 PTCD1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for PTCD1
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    tRNA binding GO:0000049 IDA
Biological Process
    tRNA 3'-end processing GO:0042780 IDA
Subcellular Localization
    mitochondrion GO:0005739 IDA
    mitochondrial matrix GO:0005759 ISS
 Experiment description of studies that identified PTCD1 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for PTCD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PTCD1 is involved
No pathways found





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