Gene description for RBMS2
Gene name RNA binding motif, single stranded interacting protein 2
Gene symbol RBMS2
Other names/aliases SCR3
Species Homo sapiens
 Database cross references - RBMS2
ExoCarta ExoCarta_5939
Vesiclepedia VP_5939
Entrez Gene 5939
HGNC 9909
MIM 602387
UniProt Q15434  
 RBMS2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Hepatocytes 26054723    
 Gene ontology annotations for RBMS2
Molecular Function
    RNA binding GO:0003723 HDA
    mRNA 3'-UTR binding GO:0003730 IBA
    poly(A) binding GO:0008143 IBA
    poly(U) RNA binding GO:0008266 IBA
Biological Process
    RNA processing GO:0006396 TAS
Subcellular Localization
    nucleus GO:0005634 IBA
    cytosol GO:0005829 IBA
    ribonucleoprotein complex GO:1990904 IBA
 Experiment description of studies that identified RBMS2 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for RBMS2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RALY 22913
Affinity Capture-MS Homo sapiens
2 NUPL2 11097
Affinity Capture-MS Homo sapiens
3 MRPS27 23107
Affinity Capture-MS Homo sapiens
4 RBMXL1  
Affinity Capture-MS Homo sapiens
5 HNRNPC 3183
Affinity Capture-MS Homo sapiens
6 APOBEC3B 9582
Affinity Capture-MS Homo sapiens
7 RPL26L1 51121
Affinity Capture-MS Homo sapiens
8 MRPL48  
Affinity Capture-MS Homo sapiens
9 ZNF346  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 MRPL30  
Affinity Capture-MS Homo sapiens
11 MRPL33  
Affinity Capture-MS Homo sapiens
12 QKI 9444
Affinity Capture-MS Homo sapiens
13 LARP1B 55132
Affinity Capture-MS Homo sapiens
14 NGRN  
Affinity Capture-MS Homo sapiens
15 NOA1  
Affinity Capture-MS Homo sapiens
16 MRPL10 124995
Affinity Capture-MS Homo sapiens
17 MRPL27 51264
Affinity Capture-MS Homo sapiens
18 PUM2 23369
Affinity Capture-MS Homo sapiens
19 PRPF3  
Affinity Capture-MS Homo sapiens
20 DHX57 90957
Affinity Capture-MS Homo sapiens
21 MRPL52  
Affinity Capture-MS Homo sapiens
22 RPUSD4 84881
Affinity Capture-MS Homo sapiens
23 MRPL49 740
Affinity Capture-MS Homo sapiens
24 RRP12 23223
Affinity Capture-MS Homo sapiens
25 SOX2  
Affinity Capture-MS Homo sapiens
26 MSI1  
Affinity Capture-MS Homo sapiens
27 MRPS18C  
Affinity Capture-MS Homo sapiens
28 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 GSPT2 23708
Affinity Capture-MS Homo sapiens
30 MRPL20 55052
Affinity Capture-MS Homo sapiens
31 HELZ 9931
Affinity Capture-MS Homo sapiens
32 PABPC4L 132430
Affinity Capture-MS Homo sapiens
33 HERC5 51191
Affinity Capture-MS Homo sapiens
34 MRPL23 6150
Affinity Capture-MS Homo sapiens
35 NUFIP1  
Affinity Capture-MS Homo sapiens
36 MRPS5 64969
Affinity Capture-MS Homo sapiens
37 YARS2  
Affinity Capture-MS Homo sapiens
38 SUPV3L1 6832
Affinity Capture-MS Homo sapiens
39 DUSP11  
Affinity Capture-MS Homo sapiens
40 MRPS24 64951
Affinity Capture-MS Homo sapiens
41 PUSL1  
Affinity Capture-MS Homo sapiens
42 MRPL57  
Affinity Capture-MS Homo sapiens
43 MRPS26 64949
Affinity Capture-MS Homo sapiens
44 HELZ2  
Affinity Capture-MS Homo sapiens
45 ZCCHC3  
Affinity Capture-MS Homo sapiens
46 STAU2 27067
Affinity Capture-MS Homo sapiens
47 ERAL1  
Affinity Capture-MS Homo sapiens
48 MRPL39 54148
Affinity Capture-MS Homo sapiens
49 DDX6 1656
Co-fractionation Homo sapiens
50 MRPS7 51081
Affinity Capture-MS Homo sapiens
51 KRR1 11103
Affinity Capture-MS Homo sapiens
52 MYCN  
Affinity Capture-MS Homo sapiens
53 MRPL4 51073
Affinity Capture-MS Homo sapiens
54 FASTKD2  
Affinity Capture-MS Homo sapiens
55 MRPL47 57129
Affinity Capture-MS Homo sapiens
56 FAM120A 23196
Affinity Capture-MS Homo sapiens
57 MTERF3  
Affinity Capture-MS Homo sapiens
58 RBM19 9904
Affinity Capture-MS Homo sapiens
59 LARP4B 23185
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 FOXP1 27086
Protein-RNA Homo sapiens
61 ATXN2 6311
Affinity Capture-MS Homo sapiens
62 MRPS30 10884
Affinity Capture-MS Homo sapiens
63 XPO1 7514
Affinity Capture-MS Homo sapiens
64 CAMK2A 815
Affinity Capture-MS Homo sapiens
65 CLK2 1196
Affinity Capture-MS Homo sapiens
66 MRPS25 64432
Affinity Capture-MS Homo sapiens
67 CDKN2AIP  
Affinity Capture-MS Homo sapiens
68 MRPL32 64983
Affinity Capture-MS Homo sapiens
69 TSR1 55720
Co-fractionation Homo sapiens
70 MRPL17  
Affinity Capture-MS Homo sapiens
71 MRPL45 84311
Affinity Capture-MS Homo sapiens
72 PINX1  
Affinity Capture-MS Homo sapiens
73 IFIT5 24138
Affinity Capture-MS Homo sapiens
74 MRPS34 65993
Affinity Capture-MS Homo sapiens
75 PHAX  
Affinity Capture-MS Homo sapiens
76 SRSF3 6428
Co-fractionation Homo sapiens
77 YBX2 51087
Affinity Capture-MS Homo sapiens
78 STAU1 6780
Affinity Capture-MS Homo sapiens
79 PTCD1 26024
Affinity Capture-MS Homo sapiens
80 PTCD3 55037
Affinity Capture-MS Homo sapiens
81 LARP4 113251
Affinity Capture-MS Homo sapiens
82 MKRN2 23609
Affinity Capture-MS Homo sapiens
83 GRAMD4 23151
Affinity Capture-MS Homo sapiens
84 MRPL51 51258
Affinity Capture-MS Homo sapiens
85 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
86 RBMS1 5937
Affinity Capture-MS Homo sapiens
87 SYNCRIP 10492
Co-fractionation Homo sapiens
88 MRPL3  
Affinity Capture-MS Homo sapiens
89 ENO1 2023
Affinity Capture-RNA Homo sapiens
90 TRUB2  
Affinity Capture-MS Homo sapiens
91 HNRNPL 3191
Affinity Capture-MS Homo sapiens
92 MRPL22  
Affinity Capture-MS Homo sapiens
93 REXO1L1P  
Affinity Capture-MS Homo sapiens
94 MRPS33  
Affinity Capture-MS Homo sapiens
95 SRPK1 6732
Biochemical Activity Homo sapiens
96 MRPL2 51069
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 TRA2B 6434
Co-fractionation Homo sapiens
98 MRPL41 64975
Affinity Capture-MS Homo sapiens
99 LARP1 23367
Affinity Capture-MS Homo sapiens
100 ZNF326 284695
Affinity Capture-MS Homo sapiens
101 ELAVL2 1993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 PAIP2B  
Affinity Capture-MS Homo sapiens
103 MRPL44  
Affinity Capture-MS Homo sapiens
104 YBX3 8531
Affinity Capture-MS Homo sapiens
105 MRPL40 64976
Affinity Capture-MS Homo sapiens
106 GLUL 2752
Affinity Capture-MS Homo sapiens
107 MRPL21 219927
Affinity Capture-MS Homo sapiens
108 MRPL46  
Affinity Capture-MS Homo sapiens
109 DAP3 7818
Affinity Capture-MS Homo sapiens
110 DHX36 170506
Affinity Capture-MS Homo sapiens
111 MRPS35 60488
Affinity Capture-MS Homo sapiens
112 MRPL35  
Affinity Capture-MS Homo sapiens
113 YBX1 4904
Affinity Capture-MS Homo sapiens
114 MRPS11  
Affinity Capture-MS Homo sapiens
115 MRPL37 51253
Affinity Capture-MS Homo sapiens
116 DHX29 54505
Affinity Capture-MS Homo sapiens
117 ZFR 51663
Affinity Capture-MS Homo sapiens
118 MRPL9 65005
Affinity Capture-MS Homo sapiens
119 MRPS14  
Affinity Capture-MS Homo sapiens
120 MRPL16  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
121 CUL3 8452
Affinity Capture-MS Homo sapiens
122 RPUSD3  
Affinity Capture-MS Homo sapiens
123 ZC3H8  
Affinity Capture-MS Homo sapiens
124 GADD45GIP1  
Affinity Capture-MS Homo sapiens
125 MRPL50 54534
Affinity Capture-MS Homo sapiens
126 ZC3H11A  
Affinity Capture-MS Homo sapiens
127 ZNF275  
Affinity Capture-MS Homo sapiens
128 NXF1 10482
Affinity Capture-RNA Homo sapiens
129 MRPS28  
Affinity Capture-MS Homo sapiens
130 YTHDC1  
Affinity Capture-MS Homo sapiens
131 MRPL1  
Affinity Capture-MS Homo sapiens
132 MRPL24  
Affinity Capture-MS Homo sapiens
133 PRR3  
Affinity Capture-MS Homo sapiens
134 EIF4H 7458
Co-fractionation Homo sapiens
135 MRPL19 9801
Affinity Capture-MS Homo sapiens
136 DKC1 1736
Affinity Capture-MS Homo sapiens
137 CMSS1  
Affinity Capture-MS Homo sapiens
138 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 DHX30 22907
Affinity Capture-MS Homo sapiens
140 PABPC5 140886
Affinity Capture-MS Homo sapiens
141 RBM45  
Affinity Capture-MS Homo sapiens
142 SART3 9733
Affinity Capture-MS Homo sapiens
143 SRSF10 10772
Affinity Capture-MS Homo sapiens
144 FAM69B  
Two-hybrid Homo sapiens
145 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
146 MRPS17 51373
Affinity Capture-MS Homo sapiens
147 MRPL38  
Affinity Capture-MS Homo sapiens
148 HIST1H1T 3010
Affinity Capture-MS Homo sapiens
149 AKAP1 8165
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 MRPL18 29074
Affinity Capture-MS Homo sapiens
151 DDX55  
Affinity Capture-MS Homo sapiens
152 PAIP1 10605
Affinity Capture-MS Homo sapiens
153 WBSCR16  
Affinity Capture-MS Homo sapiens
154 YTHDC2 64848
Affinity Capture-MS Homo sapiens
155 MRPL42  
Affinity Capture-MS Homo sapiens
156 MKRN1 23608
Affinity Capture-MS Homo sapiens
157 ZNFX1 57169
Affinity Capture-MS Homo sapiens
158 TOE1 114034
Affinity Capture-MS Homo sapiens
159 MRPS9 64965
Affinity Capture-MS Homo sapiens
160 MRPL11 65003
Affinity Capture-MS Homo sapiens
161 MCAT 27349
Affinity Capture-MS Homo sapiens
162 MRPS2 51116
Affinity Capture-MS Homo sapiens
163 HNRNPR 10236
Affinity Capture-MS Homo sapiens
164 AGO1  
Affinity Capture-MS Homo sapiens
165 ICT1 3396
Affinity Capture-MS Homo sapiens
166 MRPL15 29088
Affinity Capture-MS Homo sapiens
167 APOBEC3D  
Affinity Capture-MS Homo sapiens
168 PPHLN1  
Affinity Capture-MS Homo sapiens
169 MRPS31  
Affinity Capture-MS Homo sapiens
170 MRPL43 84545
Affinity Capture-MS Homo sapiens
171 MRPL28 10573
Affinity Capture-MS Homo sapiens
172 MALSU1  
Affinity Capture-MS Homo sapiens
173 MRPS15  
Affinity Capture-MS Homo sapiens
174 MRPS10 55173
Affinity Capture-MS Homo sapiens
175 NUP35 129401
Proximity Label-MS Homo sapiens
176 MRPS21  
Affinity Capture-MS Homo sapiens
177 SUGP2  
Affinity Capture-MS Homo sapiens
178 RBFOX2 23543
Affinity Capture-MS Homo sapiens
179 WDR33 55339
Affinity Capture-MS Homo sapiens
180 MRPS18B 28973
Affinity Capture-MS Homo sapiens
181 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
182 MOV10 4343
Affinity Capture-RNA Homo sapiens
Affinity Capture-MS Homo sapiens
183 IL17B 27190
Affinity Capture-MS Homo sapiens
184 MRPL13  
Affinity Capture-MS Homo sapiens
185 DDX28  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
186 UPF1 5976
Affinity Capture-MS Homo sapiens
187 PUM1 9698
Affinity Capture-MS Homo sapiens
188 APOBEC3F 200316
Affinity Capture-MS Homo sapiens
189 PAIP2  
Affinity Capture-MS Homo sapiens
190 CDC5L 988
Affinity Capture-MS Homo sapiens
191 MRPL55  
Affinity Capture-MS Homo sapiens
192 NUFIP2 57532
Affinity Capture-MS Homo sapiens
193 PURA 5813
Affinity Capture-MS Homo sapiens
194 GTPBP2 54676
Affinity Capture-MS Homo sapiens
195 STRBP 55342
Affinity Capture-MS Homo sapiens
196 MRPS18A  
Affinity Capture-MS Homo sapiens
197 ZKSCAN8  
Affinity Capture-MS Homo sapiens
198 IGF2BP2 10644
Affinity Capture-MS Homo sapiens
199 ZNHIT3  
Affinity Capture-MS Homo sapiens
200 CASC3  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which RBMS2 is involved
No pathways found





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