Gene description for NUFIP2
Gene name nuclear fragile X mental retardation protein interacting protein 2
Gene symbol NUFIP2
Other names/aliases 182-FIP
82-FIP
FIP-82
PIG1
Species Homo sapiens
 Database cross references - NUFIP2
ExoCarta ExoCarta_57532
Entrez Gene 57532
HGNC 17634
MIM 609356
UniProt Q7Z417  
 NUFIP2 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for NUFIP2
Molecular Function
    RNA binding GO:0003723 IDA
    poly(A) RNA binding GO:0044822 IDA
    protein binding GO:0005515 IPI
Subcellular Localization
    cytoplasm GO:0005737 IDA
    polysomal ribosome GO:0042788 IDA
    membrane GO:0016020 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified NUFIP2 in exosomes
1
Experiment ID 226
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD9|FLOT1
EV Membrane markers
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for NUFIP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FMR1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which NUFIP2 is involved
No pathways found





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