Gene description for HEXIM1
Gene name
hexamethylene bis-acetamide inducible 1
Gene symbol
HEXIM1
Other names/aliases
CLP1 EDG1 HIS1 MAQ1
Species
Homo sapiens
Database cross references - HEXIM1
ExoCarta
ExoCarta_10614
Entrez Gene
10614
HGNC
24953
MIM
607328
UniProt
O94992
HEXIM1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells
26054723
Hepatocytes
26054723
Gene ontology annotations for HEXIM1
Experiment description of studies that identified HEXIM1 in exosomes
1
Experiment ID
235
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
2
Experiment ID
237
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocytes
Sample name
MIHA
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RNA Sequencing
Protein-protein interactions for HEXIM1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
CCNT2
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
2
RELA
Affinity Capture-MS
Homo sapiens
Reconstituted Complex
Homo sapiens
3
CCNT1
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
4
RN7SK
125050
Affinity Capture-Western
Homo sapiens
5
CDK9
1025
Affinity Capture-Western
Homo sapiens
View the network
image/svg+xml
Pathways in which HEXIM1 is involved
No pathways found