Gene ontology annotations for CTTN
Experiment description of studies that identified CTTN in sEVs
1
Experiment ID
76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20224111
Organism
Homo sapiens
Experiment description
Proteomics analysis of bladder cancer exosomes.
Authors
"Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name
MCP
Publication year
2010
Sample
Bladder cancer cells
Sample name
HT1376
Isolation/purification methods
Differential centrifugation Sucrose density gradient
Flotation density
1.10-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [MALDI TOF/TOF] Western blotting FACS
2
Experiment ID
489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 6
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
3
Experiment ID
489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 6
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
4
Experiment ID
490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
5
Experiment ID
490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
6
Experiment ID
491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
7
Experiment ID
491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
8
Experiment ID
492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 9
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
9
Experiment ID
492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 9
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
10
Experiment ID
412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MCF7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
11
Experiment ID
414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MDA-MB-231
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
12
Experiment ID
426
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
13
Experiment ID
427
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
14
Experiment ID
20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
17956143
Organism
Homo sapiens
Experiment description
Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors
"Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name
JPR
Publication year
2007
Sample
Colorectal cancer cells
Sample name
HT29
Isolation/purification methods
Differential centrifugation Sucrose density gradient Diafiltration
Flotation density
1.16 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
15
Experiment ID
407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
16
Experiment ID
419
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
17
Experiment ID
419
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
18
Experiment ID
420
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
19
Experiment ID
420
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
20
Experiment ID
405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Foreskin fibroblasts
Sample name
BJ
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
21
Experiment ID
363
MISEV standards
✘
Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
33991177
Organism
Homo sapiens
Experiment description
Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors
"Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name
Proteomics
Publication year
2021
Sample
Gastric cancer cells
Sample name
MKN1 - 100K pellet
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
22
Experiment ID
364
MISEV standards
✘
Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
33991177
Organism
Homo sapiens
Experiment description
Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors
"Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name
Proteomics
Publication year
2021
Sample
Gastric cancer cells
Sample name
MKN1 - 100K pellet
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
23
Experiment ID
365
MISEV standards
✘
Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
33991177
Organism
Homo sapiens
Experiment description
Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors
"Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name
Proteomics
Publication year
2021
Sample
Gastric cancer cells
Sample name
MKN1 - 100K pellet
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
24
Experiment ID
235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
25
Experiment ID
417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Lymphoma cells
Sample name
Raji
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
26
Experiment ID
411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Mammary cancer-associated fibroblasts
Sample name
mCAF
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
27
Experiment ID
488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Homo sapiens
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Mesenchymal stem cells
Sample name
UCMSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
28
Experiment ID
418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Monocytic leukemia cells
Sample name
THP-1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
29
Experiment ID
413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Normal mammary epithelial cells
Sample name
MCF10A
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
30
Experiment ID
211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
31
Experiment ID
212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
32
Experiment ID
406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
BxPC3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
33
Experiment ID
415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
PANC-1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
34
Experiment ID
434
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
35
Experiment ID
435
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
36
Experiment ID
408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic duct epithalial cells
Sample name
HPDE
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
37
Experiment ID
409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic duct epithalial cells
Sample name
HPNE
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
38
Experiment ID
231
MISEV standards
✘
Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein Lipids
Methods used in the study
Western blotting Mass spectrometry
39
Experiment ID
232
MISEV standards
✘
Biophysical techniques
✘
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
40
Experiment ID
233
MISEV standards
✘
Biophysical techniques
✘
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
41
Experiment ID
416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pluripotent stem cells
Sample name
PSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
42
Experiment ID
275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25844599
Organism
Homo sapiens
Experiment description
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors
"Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name
Oncotarget
Publication year
2015
Sample
Prostate cancer cells
Sample name
DU145 - Docetaxel sensitive
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.12-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry/Flow cytometry/Western blotting
43
Experiment ID
274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25844599
Organism
Homo sapiens
Experiment description
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors
"Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name
Oncotarget
Publication year
2015
Sample
Prostate cancer cells
Sample name
DU145 - Docetaxel resistant
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.18 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Flow cytometry Western blotting
44
Experiment ID
410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
T lymphocytes
Sample name
Jurkat
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
Protein-protein interactions for CTTN
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
HNRNPH1
3187
Affinity Capture-RNA
Homo sapiens
Co-fractionation
Homo sapiens
2
NEDD9
4739
Affinity Capture-Western
Homo sapiens
3
MAN2C1
4123
Affinity Capture-MS
Homo sapiens
4
ACTR2
10097
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
5
MICAL1
64780
Cross-Linking-MS (XL-MS)
Homo sapiens
6
UBE2H
7328
Affinity Capture-MS
Homo sapiens
7
PPP1R9B
84687
Affinity Capture-MS
Homo sapiens
8
DLG5
9231
Affinity Capture-MS
Homo sapiens
9
OXCT1
5019
Co-fractionation
Homo sapiens
10
PPP1CB
5500
Affinity Capture-MS
Homo sapiens
11
FAM98A
25940
Affinity Capture-MS
Homo sapiens
12
UBL4A
8266
Co-fractionation
Homo sapiens
13
GART
2618
Co-fractionation
Homo sapiens
14
ARPC5L
81873
Affinity Capture-MS
Homo sapiens
15
DGKA
1606
Cross-Linking-MS (XL-MS)
Homo sapiens
16
SNX1
6642
Co-fractionation
Homo sapiens
17
CAPZA2
830
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
18
KIFC3
3801
Affinity Capture-MS
Homo sapiens
19
NOP9
161424
Affinity Capture-MS
Homo sapiens
20
RBM15B
Affinity Capture-MS
Homo sapiens
21
SHANK2
22941
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
22
RCL1
10171
Affinity Capture-MS
Homo sapiens
23
ATP6V1C1
528
Co-fractionation
Homo sapiens
24
RPA2
6118
Affinity Capture-MS
Homo sapiens
25
PRPF38A
84950
Affinity Capture-MS
Homo sapiens
26
CABIN1
Affinity Capture-MS
Homo sapiens
27
ACTC1
70
Proximity Label-MS
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
Affinity Capture-MS
Homo sapiens
28
DBN1
1627
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
29
CD2AP
23607
Affinity Capture-Western
Homo sapiens
Far Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
30
RPS19
6223
Affinity Capture-MS
Homo sapiens
31
STRN3
29966
Affinity Capture-MS
Homo sapiens
32
KIF20A
10112
Affinity Capture-MS
Homo sapiens
33
SSB
6741
Co-fractionation
Homo sapiens
34
MYO5C
55930
Affinity Capture-MS
Homo sapiens
35
SPRR2A
Reconstituted Complex
Homo sapiens
36
AIF1L
83543
Affinity Capture-MS
Homo sapiens
37
Actb
11461
Affinity Capture-MS
Mus musculus
38
PPP1R10
Affinity Capture-MS
Homo sapiens
39
NEFM
4741
Affinity Capture-MS
Homo sapiens
40
NCF1
Affinity Capture-Western
Homo sapiens
41
SOX2
Affinity Capture-MS
Homo sapiens
42
SF3B2
10992
Affinity Capture-MS
Homo sapiens
43
APEX1
328
Affinity Capture-RNA
Homo sapiens
44
TCEB3
6924
Affinity Capture-MS
Homo sapiens
45
CAPZB
832
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
46
STRN
6801
Affinity Capture-MS
Homo sapiens
47
RBM15
64783
Two-hybrid
Homo sapiens
48
PPP1R12A
4659
Affinity Capture-MS
Homo sapiens
49
GSPT2
23708
Co-fractionation
Homo sapiens
50
RDX
5962
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
51
CORO1B
57175
Co-fractionation
Homo sapiens
52
CNOT10
25904
Affinity Capture-MS
Homo sapiens
53
PRC1
9055
Affinity Capture-MS
Homo sapiens
54
USO1
8615
Co-fractionation
Homo sapiens
55
CDK9
1025
Affinity Capture-MS
Homo sapiens
56
SPECC1L
23384
Affinity Capture-MS
Homo sapiens
57
HOXA5
Affinity Capture-MS
Homo sapiens
58
CASP3
836
Biochemical Activity
Homo sapiens
Co-localization
Homo sapiens
59
ATXN2L
11273
Affinity Capture-MS
Homo sapiens
60
ACTR3
10096
Affinity Capture-Western
Homo sapiens
Proximity Label-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
Affinity Capture-MS
Homo sapiens
61
TAF2
Affinity Capture-MS
Homo sapiens
62
CALD1
800
Affinity Capture-MS
Homo sapiens
63
YES1
7525
Affinity Capture-Western
Homo sapiens
64
METAP2
10988
Affinity Capture-MS
Homo sapiens
65
RAI14
26064
Affinity Capture-MS
Homo sapiens
66
IQGAP1
8826
Affinity Capture-MS
Homo sapiens
67
CPSF7
79869
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
68
CALM3
808
Affinity Capture-MS
Homo sapiens
69
SYK
6850
Affinity Capture-Western
Homo sapiens
Co-localization
Homo sapiens
70
ABI1
10006
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
71
OBSL1
23363
Affinity Capture-MS
Homo sapiens
72
FER
2241
Affinity Capture-Western
Homo sapiens
Co-fractionation
Homo sapiens
Biochemical Activity
Homo sapiens
Co-fractionation
Homo sapiens
73
TINF2
Two-hybrid
Homo sapiens
74
Flot2
14252
Affinity Capture-MS
Mus musculus
75
TEAD1
Affinity Capture-MS
Homo sapiens
76
UGDH
7358
Co-fractionation
Homo sapiens
77
MYO1B
4430
Affinity Capture-MS
Homo sapiens
78
PEAK1
79834
Affinity Capture-MS
Homo sapiens
79
Nono
53610
Two-hybrid
Mus musculus
80
PDIA6
10130
Affinity Capture-MS
Homo sapiens
81
ATG7
10533
Co-fractionation
Homo sapiens
82
WASL
8976
Far Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
83
DDX6
1656
Affinity Capture-MS
Homo sapiens
84
Mbp
17196
Protein-peptide
Mus musculus
85
SSFA2
6744
Affinity Capture-MS
Homo sapiens
86
GTSE1
51512
Two-hybrid
Homo sapiens
87
MECP2
4204
Affinity Capture-MS
Homo sapiens
88
BTRC
8945
Affinity Capture-Western
Homo sapiens
89
CSNK1D
1453
Affinity Capture-MS
Homo sapiens
90
CHD3
1107
Two-hybrid
Homo sapiens
91
SARS
6301
Co-fractionation
Homo sapiens
92
MPRIP
23164
Affinity Capture-MS
Homo sapiens
93
TRIM15
Affinity Capture-Western
Homo sapiens
PCA
Homo sapiens
94
KIF14
9928
Affinity Capture-MS
Homo sapiens
95
PRNP
5621
Affinity Capture-MS
Homo sapiens
96
WDR1
9948
Affinity Capture-MS
Homo sapiens
97
WIPF1
7456
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
98
GARS
2617
Co-fractionation
Homo sapiens
99
CHMP4C
92421
Affinity Capture-MS
Homo sapiens
100
ARPC1B
10095
Affinity Capture-MS
Homo sapiens
101
ADAP1
Cross-Linking-MS (XL-MS)
Homo sapiens
102
PRPF6
24148
Two-hybrid
Homo sapiens
103
PLAUR
5329
Co-fractionation
Homo sapiens
104
MYO18A
399687
Affinity Capture-MS
Homo sapiens
105
UBN2
Affinity Capture-MS
Homo sapiens
106
HIST1H2BD
3017
Affinity Capture-MS
Homo sapiens
107
CNOT3
4849
Affinity Capture-MS
Homo sapiens
108
RNF4
6047
Affinity Capture-MS
Homo sapiens
109
MFAP1
Affinity Capture-MS
Homo sapiens
110
TOX4
Affinity Capture-MS
Homo sapiens
111
CAPZA1
829
Affinity Capture-MS
Homo sapiens
112
GSPT1
2935
Co-fractionation
Homo sapiens
113
STRIP1
85369
Affinity Capture-MS
Homo sapiens
114
LUZP1
7798
Affinity Capture-MS
Homo sapiens
115
PARK2
Affinity Capture-MS
Homo sapiens
116
CADPS2
Cross-Linking-MS (XL-MS)
Homo sapiens
117
RLF
6018
Cross-Linking-MS (XL-MS)
Homo sapiens
118
SHMT1
6470
Co-fractionation
Homo sapiens
119
SPTBN1
6711
Affinity Capture-MS
Homo sapiens
120
MEPCE
56257
Affinity Capture-MS
Homo sapiens
121
MYO6
4646
Affinity Capture-MS
Homo sapiens
122
RPS21
6227
Affinity Capture-MS
Homo sapiens
123
NONO
4841
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
124
ATF2
Affinity Capture-MS
Homo sapiens
125
AMOT
154796
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
126
LRRFIP2
9209
Affinity Capture-MS
Homo sapiens
127
TULP3
7289
Affinity Capture-MS
Homo sapiens
128
BRCA2
675
Affinity Capture-MS
Homo sapiens
129
SMARCA4
6597
Affinity Capture-MS
Homo sapiens
130
EFHD1
Affinity Capture-MS
Homo sapiens
131
CDH1
999
Proximity Label-MS
Homo sapiens
132
CHMP4B
128866
Affinity Capture-MS
Homo sapiens
133
CNOT1
23019
Affinity Capture-MS
Homo sapiens
134
ARPC4
10093
Affinity Capture-MS
Homo sapiens
135
MYH9
4627
Affinity Capture-MS
Homo sapiens
136
ACTN4
81
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
137
NTRK1
4914
Affinity Capture-MS
Homo sapiens
138
Hip1r
Reconstituted Complex
Mus musculus
139
ARNT
405
Affinity Capture-MS
Homo sapiens
140
SYNCRIP
10492
Affinity Capture-MS
Homo sapiens
141
PARP1
142
Affinity Capture-MS
Homo sapiens
142
NSRP1
Affinity Capture-MS
Homo sapiens
143
BICD2
23299
Proximity Label-MS
Homo sapiens
144
RPA4
Proximity Label-MS
Homo sapiens
145
ACTB
60
Proximity Label-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
146
CBLL1
Affinity Capture-Western
Homo sapiens
147
Coro1c
23790
Affinity Capture-MS
Mus musculus
148
ARPC5
10092
Affinity Capture-MS
Homo sapiens
149
DNM2
1785
Affinity Capture-Western
Homo sapiens
150
LYAR
55646
Affinity Capture-MS
Homo sapiens
151
TRIM31
Affinity Capture-MS
Homo sapiens
152
NUSAP1
51203
Affinity Capture-MS
Homo sapiens
153
PAICS
10606
Co-fractionation
Homo sapiens
154
RAD21
5885
Affinity Capture-Western
Homo sapiens
155
METTL25
Cross-Linking-MS (XL-MS)
Homo sapiens
156
Ncbp2
Affinity Capture-MS
Mus musculus
157
CCNT1
Affinity Capture-MS
Homo sapiens
158
RPS6KA1
6195
Affinity Capture-MS
Homo sapiens
159
ACD
Two-hybrid
Homo sapiens
160
ARHGAP17
55114
Reconstituted Complex
Homo sapiens
161
RRM1
6240
Co-fractionation
Homo sapiens
162
PHLPP1
Proximity Label-MS
Homo sapiens
163
GSN
2934
Affinity Capture-MS
Homo sapiens
164
TJP1
7082
Affinity Capture-MS
Homo sapiens
165
SFPQ
6421
Two-hybrid
Homo sapiens
166
FAM76B
Affinity Capture-MS
Homo sapiens
167
Zc3h11a
70579
Two-hybrid
Mus musculus
168
SDC3
Reconstituted Complex
Homo sapiens
169
HSPA9
3313
Co-fractionation
Homo sapiens
170
PRPF4B
8899
Affinity Capture-MS
Homo sapiens
171
COPS7A
50813
Co-fractionation
Homo sapiens
172
SF1
7536
Two-hybrid
Homo sapiens
173
RPS24
6229
Cross-Linking-MS (XL-MS)
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
174
PXN
5829
Co-localization
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-Western
Homo sapiens
175
SPECC1
92521
Affinity Capture-MS
Homo sapiens
176
POP1
10940
Affinity Capture-MS
Homo sapiens
177
YTHDF1
54915
Two-hybrid
Homo sapiens
178
FECH
2235
Affinity Capture-MS
Homo sapiens
179
ECT2
1894
Affinity Capture-MS
Homo sapiens
180
ASF1A
25842
Affinity Capture-MS
Homo sapiens
181
NUDT21
11051
Affinity Capture-MS
Homo sapiens
182
Rbm14
Two-hybrid
Mus musculus
183
CUL3
8452
Affinity Capture-MS
Homo sapiens
184
DCAF13
25879
Affinity Capture-MS
Homo sapiens
185
EGFR
1956
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
PCA
Homo sapiens
Affinity Capture-Luminescence
Homo sapiens
186
MYO5A
4644
Affinity Capture-MS
Homo sapiens
187
MYO19
Affinity Capture-MS
Homo sapiens
188
YY1
7528
Affinity Capture-MS
Homo sapiens
189
PTK2
5747
Affinity Capture-Western
Homo sapiens
190
CFL1
1072
Affinity Capture-MS
Homo sapiens
191
SBF1
6305
Affinity Capture-MS
Homo sapiens
192
NEXN
91624
Affinity Capture-MS
Homo sapiens
193
CORO1C
23603
Affinity Capture-MS
Homo sapiens
194
SART1
9092
Affinity Capture-MS
Homo sapiens
195
MYO1C
4641
Affinity Capture-MS
Homo sapiens
196
GLUD1
2746
Affinity Capture-MS
Homo sapiens
197
NCKIPSD
51517
Affinity Capture-MS
Homo sapiens
198
CCNT2
Affinity Capture-MS
Homo sapiens
199
SNX2
6643
Co-fractionation
Homo sapiens
200
SYNPO
11346
Affinity Capture-MS
Homo sapiens
201
TACO1
Affinity Capture-MS
Homo sapiens
202
STAT1
6772
Co-fractionation
Homo sapiens
203
Flnb
286940
Affinity Capture-MS
Mus musculus
204
MYC
Affinity Capture-MS
Homo sapiens
205
RPA3
6119
Affinity Capture-MS
Homo sapiens
Proximity Label-MS
Homo sapiens
206
NIN
51199
Proximity Label-MS
Homo sapiens
207
PPIL4
Affinity Capture-MS
Homo sapiens
208
APEH
327
Co-fractionation
Homo sapiens
209
CTTNBP2NL
Affinity Capture-MS
Homo sapiens
210
FOCAD
54914
Affinity Capture-MS
Homo sapiens
211
TOP1
7150
Affinity Capture-MS
Homo sapiens
212
HIRA
Affinity Capture-MS
Homo sapiens
213
CFL2
1073
Affinity Capture-MS
Homo sapiens
214
FIP1L1
81608
Affinity Capture-MS
Homo sapiens
215
SART3
9733
Co-fractionation
Homo sapiens
216
PRPF40A
55660
Affinity Capture-MS
Homo sapiens
217
BICD1
636
Proximity Label-MS
Homo sapiens
218
RPL23A
6147
Two-hybrid
Homo sapiens
219
TWF1
5756
Affinity Capture-MS
Homo sapiens
220
HEXIM1
10614
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
221
CSNK1E
1454
Affinity Capture-MS
Homo sapiens
222
CTNNA1
1495
Co-fractionation
Homo sapiens
223
SIK2
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
224
AKT1
207
Co-fractionation
Homo sapiens
225
ASAP1
50807
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
226
PLEKHG3
26030
Affinity Capture-MS
Homo sapiens
227
CA2
760
Affinity Capture-MS
Homo sapiens
228
MYH15
Cross-Linking-MS (XL-MS)
Homo sapiens
229
THY1
7070
Co-fractionation
Homo sapiens
230
CAMK2G
818
Affinity Capture-MS
Homo sapiens
231
PREP
5550
Co-fractionation
Homo sapiens
232
EIF3H
8667
Affinity Capture-MS
Homo sapiens
233
ARPC1A
10552
Affinity Capture-MS
Homo sapiens
234
CBX4
Affinity Capture-MS
Homo sapiens
235
SDHAF2
54949
Co-fractionation
Homo sapiens
236
CRB2
286204
Affinity Capture-Western
Homo sapiens
237
ARPC3
10094
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
238
RPL37
6167
Two-hybrid
Homo sapiens
239
TNK2
10188
Biochemical Activity
Homo sapiens
Affinity Capture-Western
Homo sapiens
240
RPS27A
6233
Affinity Capture-MS
Homo sapiens
241
ARRB2
409
Affinity Capture-MS
Homo sapiens
Co-localization
Homo sapiens
242
PLEKHA4
57664
Affinity Capture-MS
Homo sapiens
243
SPTAN1
6709
Affinity Capture-MS
Homo sapiens
244
MYLK
4638
Co-localization
Homo sapiens
Reconstituted Complex
Homo sapiens
245
METTL17
Affinity Capture-MS
Homo sapiens
246
SIRT6
Affinity Capture-MS
Homo sapiens
247
KCNA2
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
FRET
Homo sapiens
FRET
Homo sapiens
248
KIAA1671
Affinity Capture-MS
Homo sapiens
249
NXF1
10482
Two-hybrid
Homo sapiens
250
GRB2
2885
Affinity Capture-MS
Homo sapiens
251
CPSF6
11052
Affinity Capture-MS
Homo sapiens
252
PLEC
5339
Affinity Capture-MS
Homo sapiens
253
RRP1B
23076
Affinity Capture-MS
Homo sapiens
254
RBM25
58517
Affinity Capture-MS
Homo sapiens
255
LIN7A
8825
Affinity Capture-MS
Homo sapiens
256
SUCLG2
8801
Co-fractionation
Homo sapiens
257
STRN4
29888
Affinity Capture-MS
Homo sapiens
258
HDAC6
10013
Affinity Capture-Western
Homo sapiens
Biochemical Activity
Homo sapiens
Biochemical Activity
Homo sapiens
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
259
H1FX
8971
Affinity Capture-MS
Homo sapiens
260
PTBP1
5725
Co-fractionation
Homo sapiens
261
RPA1
6117
Affinity Capture-MS
Homo sapiens
262
Myo1c
17913
Affinity Capture-MS
Mus musculus
263
CDC37
11140
Affinity Capture-Luminescence
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
264
PDHA1
5160
Affinity Capture-MS
Homo sapiens
265
ARPC2
10109
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
266
KDM4C
Affinity Capture-MS
Homo sapiens
267
SMURF1
57154
Biochemical Activity
Homo sapiens
268
MAGEL2
Proximity Label-MS
Homo sapiens
269
ABL1
25
Co-fractionation
Homo sapiens
270
C1orf35
Affinity Capture-MS
Homo sapiens
271
ANKRD54
Affinity Capture-MS
Homo sapiens
272
ELAVL1
1994
Affinity Capture-RNA
Homo sapiens
273
MLH1
4292
Affinity Capture-MS
Homo sapiens
274
WDR82
80335
Affinity Capture-MS
Homo sapiens
275
VTA1
51534
Co-fractionation
Homo sapiens
276
STK26
51765
Affinity Capture-MS
Homo sapiens
277
SHMT2
6472
Co-fractionation
Homo sapiens
278
EPB41L2
2037
Affinity Capture-MS
Homo sapiens
279
SIRT1
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
Biochemical Activity
Homo sapiens
280
KCNA3
Co-localization
Homo sapiens
281
YTHDF3
Two-hybrid
Homo sapiens
282
Myh10
77579
Affinity Capture-MS
Mus musculus
283
SQSTM1
8878
Proximity Label-MS
Homo sapiens
284
ESR1
Affinity Capture-MS
Homo sapiens
285
IDE
3416
Co-fractionation
Homo sapiens
286
PPP1R9A
Affinity Capture-MS
Homo sapiens
287
TMA16
Affinity Capture-MS
Homo sapiens
288
PAX7
Affinity Capture-MS
Homo sapiens
289
SNIP1
Affinity Capture-MS
Homo sapiens
290
LRPAP1
4043
Affinity Capture-MS
Homo sapiens
291
HNRNPL
3191
Co-fractionation
Homo sapiens
292
SF3B4
10262
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
293
RPSA
3921
Affinity Capture-MS
Homo sapiens
294
ME1
4199
Co-fractionation
Homo sapiens
295
ARRB1
408
Affinity Capture-MS
Homo sapiens
296
CTTNBP2
Affinity Capture-MS
Homo sapiens
297
FLNA
2316
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
298
PINK1
Affinity Capture-MS
Homo sapiens
299
MYO1E
4643
Co-fractionation
Homo sapiens
300
FLNB
2317
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
301
DDX42
11325
Affinity Capture-MS
Homo sapiens
302
SERBP1
26135
Affinity Capture-MS
Homo sapiens
303
EIF5A
1984
Affinity Capture-MS
Homo sapiens
304
SNW1
22938
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
305
PCBP1
5093
Proximity Label-MS
Homo sapiens
306
SH2D4A
63898
Affinity Capture-MS
Homo sapiens
307
PIP4K2A
5305
Affinity Capture-MS
Homo sapiens
308
NUFIP2
57532
Affinity Capture-MS
Homo sapiens
309
PSPC1
55269
Affinity Capture-MS
Homo sapiens
310
NDE1
54820
Affinity Capture-MS
Homo sapiens
311
NDC80
10403
Affinity Capture-MS
Homo sapiens
312
VIM
7431
Affinity Capture-MS
Homo sapiens
313
Pspc1
Two-hybrid
Mus musculus
314
PRMT1
3276
Affinity Capture-MS
Homo sapiens
315
GRIA2
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
316
ARPC4-TTLL3
100526693
Affinity Capture-MS
Homo sapiens
317
DDX56
Affinity Capture-MS
Homo sapiens
318
SHC1
6464
Affinity Capture-MS
Homo sapiens
319
RANBP2
5903
Co-fractionation
Homo sapiens
320
EP300
2033
Affinity Capture-Western
Homo sapiens
321
CTNND1
1500
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
322
SH3PXD2A
9644
Affinity Capture-Western
Homo sapiens
View the network
image/svg+xml
Pathways in which CTTN is involved