Experiment description of studies that identified STRN4 in exosomes

1 Experiment ID 236 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

3 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

Protein-protein interactions for STRN4

Protein Interactor ExoCarta ID Identification method PubMed Species 1 TRAF3IP3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 ZNF211   Affinity Capture-MS Homo sapiens 3 STK25 10494 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 4 PAXIP1   Affinity Capture-MS Homo sapiens 5 SIKE1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 Strip1   Affinity Capture-MS Mus musculus 7 RABEP2 79874 Affinity Capture-MS Homo sapiens 8 RIT1 6016 Negative Genetic Homo sapiens 9 TPTE2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 10 APC   Affinity Capture-MS Homo sapiens 11 GDF9 2661 Two-hybrid Homo sapiens 12 MAGEA1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 13 STRN3 29966 Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens 14 GOLGA6A   Affinity Capture-MS Homo sapiens 15 MAP4K4 9448 Affinity Capture-MS Homo sapiens 16 PI4KA 5297 Two-hybrid Homo sapiens 17 PDCD10 11235 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 STRN 6801 Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens 19 CEMIP 57214 Affinity Capture-MS Homo sapiens 20 AK5 26289 Two-hybrid Homo sapiens 21 FILIP1   Affinity Capture-MS Homo sapiens 22 DYNLL1 8655 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 TULP3 7289 Affinity Capture-MS Homo sapiens 24 ZNF219   Affinity Capture-MS Homo sapiens 25 STRIP1 85369 Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens 26 CTTNBP2NL   Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens 27 EEF1A1 1915 Co-fractionation Homo sapiens 28 GEMIN2 8487 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 29 CCT2 10576 Affinity Capture-MS Homo sapiens 30 KRT8 3856 Proximity Label-MS Homo sapiens 31 CLDN12 9069 Two-hybrid Homo sapiens 32 ZNF550   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 33 ZNF444   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 34 MCC 4163 Affinity Capture-MS Homo sapiens 35 MOB4 25843 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens 36 KLHDC2   Two-hybrid Homo sapiens 37 PARK2   Affinity Capture-MS Homo sapiens 38 NR1H3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 NONO 4841 Co-fractionation Homo sapiens 40 GOLGA8G   Affinity Capture-MS Homo sapiens 41 GOLGA2 2801 Proximity Label-MS Homo sapiens 42 Ppp2ca 19052 Affinity Capture-MS Mus musculus 43 BRCA2 675 Affinity Capture-MS Homo sapiens 44 NTRK1 4914 Affinity Capture-MS Homo sapiens 45 TOX4   Co-fractionation Homo sapiens 46 PPP2CA 5515 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 47 STXBP4 252983 Affinity Capture-MS Homo sapiens 48 RPA4   Proximity Label-MS Homo sapiens 49 DYNLL2 140735 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 50 HIST1H2BK 85236 Cross-Linking-MS (XL-MS) Homo sapiens 51 AGPS 8540 Proximity Label-MS Homo sapiens 52 CTTNBP2   Affinity Capture-MS Homo sapiens 53 RMDN3 55177 Proximity Label-MS Homo sapiens 54 C7orf50 84310 Cross-Linking-MS (XL-MS) Homo sapiens 55 SNAP29 9342 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 56 Ppp2r1a 51792 Affinity Capture-MS Mus musculus 57 MINK1 50488 Affinity Capture-MS Homo sapiens 58 STK3 6788 Proximity Label-MS Homo sapiens 59 Strn3   Affinity Capture-MS Mus musculus 60 C9orf78 51759 Affinity Capture-MS Homo sapiens 61 PIP 5304 Affinity Capture-MS Homo sapiens 62 NBEA   Two-hybrid Homo sapiens 63 PSMD13 5719 Co-fractionation Homo sapiens 64 TNFRSF1A 7132 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 65 CTTN 2017 Affinity Capture-MS Homo sapiens 66 EGFR 1956 Negative Genetic Homo sapiens 67 PCOLCE2 26577 Affinity Capture-MS Homo sapiens 68 METTL21B   Affinity Capture-MS Homo sapiens 69 EEF1B2 1933 Co-fractionation Homo sapiens 70 ZNF223   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 71 DCTN1 1639 Co-fractionation Homo sapiens 72 NXF1 10482 Affinity Capture-RNA Homo sapiens 73 JUN 3725 Reconstituted Complex Homo sapiens 74 MTG1   Two-hybrid Homo sapiens 75 PPP2R1A 5518 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 76 RPA3 6119 Proximity Label-MS Homo sapiens 77 CSNK2A2 1459 Affinity Capture-MS Homo sapiens 78 GOLGA1   Proximity Label-MS Homo sapiens 79 DDB1 1642 Co-fractionation Homo sapiens 80 Dynll1 56455 Affinity Capture-MS Mus musculus 81 STK4 6789 Proximity Label-MS Homo sapiens 82 SLC25A6 293 Two-hybrid Homo sapiens 83 HSPD1 3329 Co-fractionation Homo sapiens 84 PPP2CB 5516 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 85 ZRANB1 54764 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 86 RASSF3 283349 Affinity Capture-MS Homo sapiens 87 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 88 STK24 8428 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 89 GIPC1 10755 Proximity Label-MS Homo sapiens 90 PLP1 5354 Affinity Capture-MS Homo sapiens 91 SLMAP 7871 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens 92 PRDM14   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 93 ZNF264   Affinity Capture-MS Homo sapiens 94 ASNS 440 Two-hybrid Homo sapiens 95 ISCA2 122961 Affinity Capture-MS Homo sapiens 96 SPINK2   Affinity Capture-MS Homo sapiens 97 STRIP2   Affinity Capture-MS Homo sapiens 98 HIST1H2BC 8347 Cross-Linking-MS (XL-MS) Homo sapiens 99 DDX39B 7919 Two-hybrid Homo sapiens 100 DCTN2 10540 Co-fractionation Homo sapiens 101 PPP2R2C 5522 Affinity Capture-MS Homo sapiens 102 STK26 51765 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 103 SHMT2 6472 Affinity Capture-RNA Homo sapiens 104 DDX58 23586 Affinity Capture-RNA Homo sapiens 105 YPEL1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 106 DYNC1H1 1778 Co-fractionation Homo sapiens 107 TCL1B   Affinity Capture-MS Homo sapiens 108 MOV10 4343 Affinity Capture-RNA Homo sapiens 109 PSMA5 5686 Affinity Capture-MS Homo sapiens 110 FGFR1OP2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 111 STARD10 10809 Cross-Linking-MS (XL-MS) Homo sapiens 112 NHSL2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 113 ZNF331   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 114 ECSIT 51295 Two-hybrid Homo sapiens View the network

Pathways in which STRN4 is involved

No pathways found