Experiment description of studies that identified STRN4 in exosomes

1 Experiment ID 236 MISEV standards ✔ EM EV Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH EV Enriched markers ✔ HSP90B1 EV Negative markers ✔ qNano EV Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 237 MISEV standards ✔ EM EV Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH EV Enriched markers ✔ HSP90B1 EV Negative markers ✔ qNano EV Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

3 Experiment ID 488 MISEV standards ✔ EM EV Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 EV Enriched markers ✔ CANX EV Negative markers ✔ NTA EV Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ. Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

Protein-protein interactions for STRN4

Protein Interactor ExoCarta ID Identification method PubMed Species 1 STRIP1 85369 Affinity Capture-MS Homo sapiens 2 BAT1   Two-hybrid Homo sapiens 3 STK25 10494 Affinity Capture-MS Homo sapiens 4 SLC25A6 293 Two-hybrid Homo sapiens 5 FLJ21168   Affinity Capture-MS Homo sapiens 6 NBEA   Two-hybrid Homo sapiens 7 ASNS 440 Two-hybrid Homo sapiens 8 T3JAM   Affinity Capture-MS Homo sapiens 9 CLDN12 9069 Two-hybrid Homo sapiens 10 GDF9 2661 Two-hybrid Homo sapiens 11 GTP   Two-hybrid Homo sapiens 12 STRN3 29966 Affinity Capture-MS Homo sapiens 13 MCC 4163 Affinity Capture-MS Homo sapiens 14 MOB4 25843 Affinity Capture-MS Homo sapiens 15 KLHDC2   Two-hybrid Homo sapiens 16 STK26 51765 Affinity Capture-MS Homo sapiens 17 PI4KA 5297 Two-hybrid Homo sapiens 18 PDCD10 11235 Affinity Capture-MS Homo sapiens 19 STK24 8428 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 DKFZp547A023   Affinity Capture-MS Homo sapiens 21 STRN 6801 Affinity Capture-MS Homo sapiens 22 AK5 26289 Two-hybrid Homo sapiens 23 PPP2CA 5515 Affinity Capture-MS Homo sapiens 24 PPP2R1A 5518 Affinity Capture-MS Homo sapiens 25 PPP2CB 5516 Affinity Capture-MS Homo sapiens 26 CTTNBP2   Affinity Capture-MS Homo sapiens 27 ECSIT 51295 Two-hybrid Homo sapiens View the network

Pathways in which STRN4 is involved

No pathways found