Experiment description of studies that identified PLP1 in exosomes

1 Experiment ID 255 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|FLOT1 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25950383     Organism Homo sapiens Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L" Journal name Pigment Cell Melanoma Res Publication year 2015 Sample Melanoma cells Sample name G1 Isolation/purification methods Differential centrifugation Unltracentrifugation Sucrose density gradient Flotation density 1.13 - 1.19 g/mL Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 256 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|FLOT1 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25950383     Organism Homo sapiens Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L" Journal name Pigment Cell Melanoma Res Publication year 2015 Sample Melanoma cells Sample name 501mel Isolation/purification methods Differential centrifugation Unltracentrifugation Sucrose density gradient Flotation density 1.13 - 1.19 g/mL Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

3 Experiment ID 257 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|FLOT1 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25950383     Organism Homo sapiens Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L" Journal name Pigment Cell Melanoma Res Publication year 2015 Sample Melanoma cells Sample name Daju Isolation/purification methods Differential centrifugation Unltracentrifugation Sucrose density gradient Flotation density 1.13 - 1.19 g/mL Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

4 Experiment ID 258 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|FLOT1|CD81 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25950383     Organism Homo sapiens Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L" Journal name Pigment Cell Melanoma Res Publication year 2015 Sample Melanoma cells Sample name SKMEL28 Isolation/purification methods Differential centrifugation Unltracentrifugation Sucrose density gradient Flotation density 1.13 - 1.19 g/mL Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

5 Experiment ID 191 MISEV standards ✘ Biophysical techniques ✔ Alix|CD81|CD9 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 20124223     Organism Homo sapiens Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK." Journal name Mol Cell Proteomics Publication year 2010 Sample Squamous carcinoma cells Sample name Squamous carcinoma cell (A431) Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for PLP1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 SLC10A6   Two-hybrid Homo sapiens 2 SIKE1   Affinity Capture-MS Homo sapiens 3 TARDBP 23435 Affinity Capture-MS Homo sapiens 4 JPH1 56704 Two-hybrid Homo sapiens 5 PDDC1 347862 Affinity Capture-MS Homo sapiens 6 PI16   Two-hybrid Homo sapiens 7 STX4 6810 Two-hybrid Homo sapiens 8 MS4A3   Two-hybrid Homo sapiens 9 MYADM 91663 Two-hybrid Homo sapiens 10 TMPRSS2 7113 Two-hybrid Homo sapiens 11 STX1A 6804 Two-hybrid Homo sapiens 12 MUC1 4582 Two-hybrid Homo sapiens 13 CALN1   Two-hybrid Homo sapiens 14 JAGN1 84522 Two-hybrid Homo sapiens 15 KLRC1   Two-hybrid Homo sapiens 16 TMEM182   Two-hybrid Homo sapiens 17 MBP 4155 Co-purification Homo sapiens Reconstituted Complex Homo sapiens 18 TMEM97 27346 Two-hybrid Homo sapiens 19 FCRL2   Two-hybrid Homo sapiens 20 U2AF1 7307 Affinity Capture-MS Homo sapiens 21 VAT1 10493 Two-hybrid Homo sapiens 22 STRIP1 85369 Affinity Capture-MS Homo sapiens 23 CLN8 2055 Two-hybrid Homo sapiens 24 LEPROTL1 23484 Two-hybrid Homo sapiens 25 TMEM254   Two-hybrid Homo sapiens 26 TMEM106C 79022 Two-hybrid Homo sapiens 27 TMEM14B   Two-hybrid Homo sapiens 28 SLC1A5 6510 Two-hybrid Homo sapiens 29 IFITM3 10410 Two-hybrid Homo sapiens 30 SPNS3   Two-hybrid Homo sapiens 31 RELL2   Two-hybrid Homo sapiens 32 GAST   Two-hybrid Homo sapiens 33 HAS3   Two-hybrid Homo sapiens 34 SLX4   Affinity Capture-MS Homo sapiens 35 TMEM243   Two-hybrid Homo sapiens 36 TMEM45B 120224 Two-hybrid Homo sapiens 37 CREB3   Two-hybrid Homo sapiens 38 SLC35E3   Two-hybrid Homo sapiens 39 ARL13B 200894 Two-hybrid Homo sapiens 40 LHFPL5   Two-hybrid Homo sapiens 41 C17orf62 79415 Two-hybrid Homo sapiens 42 MFF 56947 Two-hybrid Homo sapiens 43 RMDN3 55177 Two-hybrid Homo sapiens 44 CDIPT 10423 Two-hybrid Homo sapiens 45 UPK2 7379 Two-hybrid Homo sapiens 46 REEP5 7905 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 47 TMEM52B 120939 Two-hybrid Homo sapiens 48 CD40 958 Two-hybrid Homo sapiens 49 RNF24   Two-hybrid Homo sapiens 50 C4orf32   Affinity Capture-MS Homo sapiens 51 FNDC9   Two-hybrid Homo sapiens 52 FFAR2   Two-hybrid Homo sapiens 53 SLC41A3 54946 Two-hybrid Homo sapiens 54 MTIF3   Two-hybrid Homo sapiens 55 MS4A4A   Two-hybrid Homo sapiens 56 ERGIC3 51614 Two-hybrid Homo sapiens 57 GPR97   Two-hybrid Homo sapiens 58 RTN2 6253 Affinity Capture-MS Homo sapiens 59 HTR2C   Two-hybrid Homo sapiens 60 CREB3L1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 61 TMEM242   Two-hybrid Homo sapiens 62 SUSD3 203328 Two-hybrid Homo sapiens 63 LEUTX   Two-hybrid Homo sapiens 64 FAM209A 200232 Two-hybrid Homo sapiens 65 GPR42   Two-hybrid Homo sapiens 66 EDA2R   Two-hybrid Homo sapiens 67 AQP10   Two-hybrid Homo sapiens 68 PTPRN   Two-hybrid Homo sapiens Two-hybrid Homo sapiens Two-hybrid Homo sapiens 69 SLC35E2 9906 Two-hybrid Homo sapiens 70 RNF114 55905 Affinity Capture-MS Homo sapiens 71 CLDN20   Two-hybrid Homo sapiens 72 REEP6   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 73 NRG1 3084 Two-hybrid Homo sapiens 74 CLDN2 9075 Two-hybrid Homo sapiens 75 PIGP   Two-hybrid Homo sapiens 76 SMIM3   Two-hybrid Homo sapiens 77 SLMAP 7871 Affinity Capture-MS Homo sapiens 78 SLC16A2   Two-hybrid Homo sapiens 79 STRN4 29888 Affinity Capture-MS Homo sapiens 80 IER3IP1 51124 Two-hybrid Homo sapiens 81 SLC26A6 65010 Two-hybrid Homo sapiens 82 Htt   Affinity Capture-MS Mus musculus 83 ITGAV 3685 Affinity Capture-Western Homo sapiens 84 NRAS 4893 Affinity Capture-MS Homo sapiens 85 FGFR1OP2   Affinity Capture-MS Homo sapiens 86 GPR61   Two-hybrid Homo sapiens 87 TMEM31   Two-hybrid Homo sapiens 88 STRN 6801 Affinity Capture-MS Homo sapiens 89 ELOVL4   Two-hybrid Homo sapiens 90 MGST3 4259 Two-hybrid Homo sapiens 91 DYSF 8291 Two-hybrid Homo sapiens View the network

Pathways in which PLP1 is involved

No pathways found