Gene description for TMEM45B
Gene name transmembrane protein 45B
Gene symbol TMEM45B
Other names/aliases -
Species Homo sapiens
 Database cross references - TMEM45B
ExoCarta ExoCarta_120224
Entrez Gene 120224
HGNC 25194
UniProt Q96B21  
 TMEM45B identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 25890246    
 Gene ontology annotations for TMEM45B
Subcellular Localization
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified TMEM45B in exosomes
1
Experiment ID 286
ISEV standards
CEM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81|EpCAM
EV Membrane markers
EV Negative markers
DLS
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors Xu R, Greening DW, Rai A, Ji H, Simpson RJ.
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for TMEM45B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TMEM45B is involved
No pathways found





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