Gene description for SMAP2
Gene name small ArfGAP2
Gene symbol SMAP2
Other names/aliases SMAP1L
Species Homo sapiens
 Database cross references - SMAP2
ExoCarta ExoCarta_64744
Vesiclepedia VP_64744
Entrez Gene 64744
HGNC 25082
UniProt Q8WU79  
 SMAP2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for SMAP2
Molecular Function
    GTPase activator activity GO:0005096 IBA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified SMAP2 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SMAP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CDIPT 10423
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 VCAM1 7412
Affinity Capture-MS Homo sapiens
3 SLC2A12 154091
Affinity Capture-MS Homo sapiens
4 GTSE1 51512
Affinity Capture-MS Homo sapiens
5 GJD3  
Proximity Label-MS Homo sapiens
6 SLC25A11 8402
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 EBAG9 9166
Proximity Label-MS Homo sapiens
8 CLINT1 9685
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 LAMTOR1 55004
Proximity Label-MS Homo sapiens
10 LAMP3  
Proximity Label-MS Homo sapiens
11 SLC2A4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 CPEB1  
Proximity Label-MS Homo sapiens
13 BAG2 9532
Affinity Capture-MS Homo sapiens
14 AP2B1 163
Proximity Label-MS Homo sapiens
15 SLC22A12 116085
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 SQSTM1 8878
Proximity Label-MS Homo sapiens
17 XPO1 7514
Affinity Capture-MS Homo sapiens
18 ZNF143  
Affinity Capture-MS Homo sapiens
19 ARF3 377
Proximity Label-MS Homo sapiens
20 DAB1 1600
Two-hybrid Homo sapiens
21 ATG9A 79065
Proximity Label-MS Homo sapiens
22 LAMP2 3920
Proximity Label-MS Homo sapiens
23 FAM168A  
Two-hybrid Homo sapiens
24 ARHGAP18 93663
Affinity Capture-MS Homo sapiens
25 RBMS1 5937
Affinity Capture-MS Homo sapiens
26 AQP3  
Affinity Capture-MS Homo sapiens
27 MFSD4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 DDX58 23586
Affinity Capture-RNA Homo sapiens
29 CELF5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 FN1 2335
Affinity Capture-MS Homo sapiens
31 RAB4A 5867
Proximity Label-MS Homo sapiens
32 DAZAP2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
33 MFSD11  
Affinity Capture-MS Homo sapiens
34 MAGED1 9500
Two-hybrid Homo sapiens
35 SLC5A8 160728
Affinity Capture-MS Homo sapiens
36 SMAD9  
Affinity Capture-MS Homo sapiens
37 SLC2A14 144195
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 CLTA 1211
Proximity Label-MS Homo sapiens
39 HSPA1A 3303
Affinity Capture-MS Homo sapiens
40 TMEM45B 120224
Affinity Capture-MS Homo sapiens
41 CLTB 1212
Proximity Label-MS Homo sapiens
42 CRYZ 1429
Co-fractionation Homo sapiens
43 STAMBPL1  
Affinity Capture-MS Homo sapiens
44 SLC22A4 6583
Affinity Capture-MS Homo sapiens
45 RHOA 387
Affinity Capture-MS Homo sapiens
46 C1orf94  
Two-hybrid Homo sapiens
47 ARF4 378
Proximity Label-MS Homo sapiens
48 DNAJC6  
Proximity Label-MS Homo sapiens
49 STX6 10228
Proximity Label-MS Homo sapiens
50 RAB11A 8766
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SMAP2 is involved
No pathways found





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