Gene description for SLC5A8
Gene name solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
Gene symbol SLC5A8
Other names/aliases AIT
SMCT
SMCT1
Species Homo sapiens
 Database cross references - SLC5A8
ExoCarta ExoCarta_160728
Entrez Gene 160728
HGNC 19119
MIM 608044
UniProt Q8N695  
 SLC5A8 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for SLC5A8
Molecular Function
    symporter activity GO:0015293 IEA
Biological Process
    ion transport GO:0006811 TAS
    transmembrane transport GO:0055085 TAS
    sodium ion transport GO:0006814 IEA
    apoptotic process GO:0006915 IEA
Subcellular Localization
    plasma membrane GO:0005886 TAS
    apical plasma membrane GO:0016324 IEA
    integral component of membrane GO:0016021 IEA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified SLC5A8 in exosomes
1
Experiment ID 63
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SLC5A8
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLC5A8 is involved
PathwayEvidenceSource
Organic anion transporters TAS Reactome





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