Gene description for LMNA
Gene name lamin A/C
Gene symbol LMNA
Other names/aliases CDCD1
CDDC
CMD1A
CMT2B1
EMD2
FPL
FPLD
FPLD2
HGPS
IDC
LDP1
LFP
LGMD1B
LMN1
LMNC
LMNL1
PRO1
Species Homo sapiens
 Database cross references - LMNA
ExoCarta ExoCarta_4000
Vesiclepedia VP_4000
Entrez Gene 4000
HGNC 6636
MIM 150330
UniProt P02545  
 LMNA identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for LMNA
Molecular Function
    structural molecule activity GO:0005198 TAS
    structural constituent of cytoskeleton GO:0005200 IBA
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
    structural constituent of nuclear lamina GO:0160123 IDA
Biological Process
    protein import into nucleus GO:0006606 IEA
    nuclear envelope organization GO:0006998 IBA
    nuclear envelope organization GO:0006998 IDA
    nuclear envelope organization GO:0006998 IMP
    nuclear migration GO:0007097 IBA
    muscle organ development GO:0007517 IMP
    protein localization GO:0008104 IMP
    negative regulation of cell population proliferation GO:0008285 IMP
    positive regulation of gene expression GO:0010628 IEA
    regulation of cell migration GO:0030334 ISS
    establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 ISS
    heterochromatin formation GO:0031507 IBA
    regulation of protein stability GO:0031647 IEA
    regulation of telomere maintenance GO:0032204 IMP
    protein localization to nucleus GO:0034504 ISS
    nuclear pore localization GO:0051664 IBA
    ventricular cardiac muscle cell development GO:0055015 IEA
    cellular response to hypoxia GO:0071456 IEP
    negative regulation of mesenchymal cell proliferation GO:0072201 IEA
    negative regulation of release of cytochrome c from mitochondria GO:0090201 IEA
    cellular senescence GO:0090398 IDA
    protein localization to nuclear envelope GO:0090435 IBA
    regulation of protein localization to nucleus GO:1900180 IEA
    negative regulation of cardiac muscle hypertrophy in response to stress GO:1903243 ISS
    DNA double-strand break attachment to nuclear envelope GO:1990683 IDA
    negative regulation of extrinsic apoptotic signaling pathway GO:2001237 IEA
Subcellular Localization
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IDA
    nuclear envelope GO:0005635 IDA
    nuclear envelope GO:0005635 IMP
    nuclear envelope GO:0005635 TAS
    lamin filament GO:0005638 IEA
    lamin filament GO:0005638 TAS
    nuclear lamina GO:0005652 IBA
    nuclear lamina GO:0005652 IDA
    nuclear lamina GO:0005652 TAS
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    cytosol GO:0005829 TAS
    intermediate filament GO:0005882 TAS
    nuclear matrix GO:0016363 IDA
    nuclear speck GO:0016607 IDA
    nuclear membrane GO:0031965 HDA
    site of double-strand break GO:0035861 IDA
    perinuclear region of cytoplasm GO:0048471 IDA
 Experiment description of studies that identified LMNA in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
16
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
17
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
18
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
30
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
31
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
35
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
39
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
43
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
44
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for LMNA
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
2 ITGB1 3688
Proximity Label-MS Homo sapiens
3 CDCA2 157313
Proximity Label-MS Homo sapiens
4 KRT37 8688
Affinity Capture-MS Homo sapiens
5 ISG15 9636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 TRMT1L 81627
Proximity Label-MS Homo sapiens
7 DGCR14  
Proximity Label-MS Homo sapiens
8 KPNA1 3836
Co-fractionation Homo sapiens
9 PDAP1 11333
Co-fractionation Homo sapiens
10 TOP2B 7155
Proximity Label-MS Homo sapiens
11 CSNK1A1 1452
Proximity Label-MS Homo sapiens
12 C9orf78 51759
Proximity Label-MS Homo sapiens
13 FAM13C  
Affinity Capture-MS Homo sapiens
14 PRKDC 5591
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
15 CKB 1152
Affinity Capture-MS Homo sapiens
16 KBTBD6  
Proximity Label-MS Homo sapiens
17 GPATCH4 54865
Proximity Label-MS Homo sapiens
18 MASTL  
Proximity Label-MS Homo sapiens
19 NOXO1  
Affinity Capture-MS Homo sapiens
20 WDR76  
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
21 RBM6 10180
Proximity Label-MS Homo sapiens
22 PELI1 57162
Two-hybrid Homo sapiens
23 KIF23 9493
Affinity Capture-MS Homo sapiens
24 TMEM41B 440026
Proximity Label-MS Homo sapiens
25 SMPD4 55627
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
26 TM9SF1 10548
Proximity Label-MS Homo sapiens
27 TFIP11  
Two-hybrid Homo sapiens
28 SMC2 10592
Cross-Linking-MS (XL-MS) Homo sapiens
29 HELLS 3070
Proximity Label-MS Homo sapiens
30 ACLY 47
Co-fractionation Homo sapiens
31 NFATC2IP  
Proximity Label-MS Homo sapiens
32 USP33  
Proximity Label-MS Homo sapiens
33 MARCKSL1 65108
Affinity Capture-MS Homo sapiens
34 UCHL5 51377
Reconstituted Complex Homo sapiens
35 F2RL1  
Affinity Capture-MS Homo sapiens
36 PSMD5 5711
Proximity Label-MS Homo sapiens
37 MECP2 4204
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
38 BUD31 8896
Proximity Label-MS Homo sapiens
39 SLU7  
Proximity Label-MS Homo sapiens
40 SOD1 6647
Affinity Capture-MS Homo sapiens
41 DYNLT1 6993
Co-fractionation Homo sapiens
42 KIF14 9928
Affinity Capture-MS Homo sapiens
43 EMC1 23065
Proximity Label-MS Homo sapiens
44 CAMLG 819
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
45 RBMX 27316
Proximity Label-MS Homo sapiens
46 HEXIM1 10614
Affinity Capture-MS Homo sapiens
47 CHMP4C 92421
Affinity Capture-MS Homo sapiens
48 AP3M1 26985
Proximity Label-MS Homo sapiens
49 SPTA1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
50 ZNF444  
Affinity Capture-MS Homo sapiens
51 ADPGK 83440
Proximity Label-MS Homo sapiens
52 TMX1 81542
Proximity Label-MS Homo sapiens
53 MAP1B 4131
Affinity Capture-MS Homo sapiens
54 C17orf49 124944
Affinity Capture-MS Homo sapiens
55 SRSF3 6428
Proximity Label-MS Homo sapiens
56 MAD1L1  
Co-fractionation Homo sapiens
57 TMTC3 160418
Proximity Label-MS Homo sapiens
58 HIST1H3E 8353
Co-purification Homo sapiens
59 MAGT1 84061
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
60 CDH1 999
Affinity Capture-MS Homo sapiens
61 UBA3 9039
Proximity Label-MS Homo sapiens
62 YAP1 10413
Affinity Capture-MS Homo sapiens
63 TRIM21 6737
Affinity Capture-MS Homo sapiens
64 ZKSCAN4  
Proximity Label-MS Homo sapiens
65 NOC4L 79050
Proximity Label-MS Homo sapiens
66 SYNE1 23345
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
67 DTX2 113878
Proximity Label-MS Homo sapiens
68 KIAA1143  
Proximity Label-MS Homo sapiens
69 BANF1 8815
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 YWHAQ 10971
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
71 ENO1 2023
Affinity Capture-RNA Homo sapiens
72 WHSC1L1  
Proximity Label-MS Homo sapiens
73 DDX39B 7919
Affinity Capture-MS Homo sapiens
74 AHCTF1 25909
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
75 SEC61B 10952
Proximity Label-MS Homo sapiens
76 TEAD4  
Proximity Label-MS Homo sapiens
77 SLC25A5 292
Co-fractionation Homo sapiens
78 KRTAP10-7  
Two-hybrid Homo sapiens
79 SCARNA22  
Affinity Capture-RNA Homo sapiens
80 ANLN 54443
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
81 SMYD5 10322
Proximity Label-MS Homo sapiens
82 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
83 TMPO 7112
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
84 BRF1  
Affinity Capture-MS Homo sapiens
85 EARS2  
Proximity Label-MS Homo sapiens
86 GMPPB 29925
Co-fractionation Homo sapiens
87 SUGP1  
Proximity Label-MS Homo sapiens
88 NASP 4678
Affinity Capture-MS Homo sapiens
89 KIF20A 10112
Affinity Capture-MS Homo sapiens
90 SDHA 6389
Affinity Capture-MS Homo sapiens
91 TYMS 7298
Proximity Label-MS Homo sapiens
92 SIRT7  
Affinity Capture-MS Homo sapiens
93 ZNF564  
Two-hybrid Homo sapiens
94 ANXA1 301
Protein-peptide Homo sapiens
95 TMEM199  
Proximity Label-MS Homo sapiens
96 ATP6AP2 10159
Proximity Label-MS Homo sapiens
97 YWHAZ 7534
Co-fractionation Homo sapiens
98 GZMA 3001
Biochemical Activity Homo sapiens
99 RBBP4 5928
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
100 FN1 2335
Affinity Capture-MS Homo sapiens
101 BAZ2A  
Proximity Label-MS Homo sapiens
102 SAAL1 113174
Proximity Label-MS Homo sapiens
103 ZW10 9183
Co-fractionation Homo sapiens
104 ARHGAP44  
Affinity Capture-MS Homo sapiens
105 PCBP1 5093
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
106 HECW2  
Affinity Capture-Western Homo sapiens
107 DLST 1743
Affinity Capture-MS Homo sapiens
108 HIST1H1A 3024
Co-fractionation Homo sapiens
109 STMN1 3925
Affinity Capture-MS Homo sapiens
110 FAM169A  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
111 ILK 3611
Affinity Capture-MS Homo sapiens
112 PEX3 8504
Proximity Label-MS Homo sapiens
113 FAM133A 286499
Cross-Linking-MS (XL-MS) Homo sapiens
114 PAIP1 10605
Proximity Label-MS Homo sapiens
115 TMSB10 9168
Affinity Capture-MS Homo sapiens
116 NOSIP 51070
Proximity Label-MS Homo sapiens
117 NUDT21 11051
Affinity Capture-MS Homo sapiens
118 PEX11B 8799
Proximity Label-MS Homo sapiens
119 ARHGDIA 396
Affinity Capture-MS Homo sapiens
120 RAB27B 5874
Proximity Label-MS Homo sapiens
121 DEGS1  
Proximity Label-MS Homo sapiens
122 RRP1 8568
Proximity Label-MS Homo sapiens
123 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
124 RHOC 389
Proximity Label-MS Homo sapiens
125 APRT 353
Proximity Label-MS Homo sapiens
126 MORF4L2  
Affinity Capture-MS Homo sapiens
127 PTPN2 5771
Proximity Label-MS Homo sapiens
128 PMM2 5373
Proximity Label-MS Homo sapiens
129 LONP1 9361
Proximity Label-MS Homo sapiens
130 NCL 4691
Co-fractionation Homo sapiens
131 ALYREF 10189
Proximity Label-MS Homo sapiens
132 NDC1 55706
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
133 PSMA7 5688
Affinity Capture-MS Homo sapiens
134 FAM50A 9130
Proximity Label-MS Homo sapiens
135 ACO2 50
Affinity Capture-MS Homo sapiens
136 CISD2 493856
Proximity Label-MS Homo sapiens
137 CUL7 9820
Affinity Capture-MS Homo sapiens
138 COLGALT1 79709
Co-fractionation Homo sapiens
139 NFIC 4782
Co-fractionation Homo sapiens
140 PCYT1A 5130
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
141 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
142 GSTP1 2950
Affinity Capture-MS Homo sapiens
143 KPNA6 23633
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
144 HSP90AB2P 391634
Proximity Label-MS Homo sapiens
145 KPNA3 3839
Co-fractionation Homo sapiens
146 TOR1A 1861
Reconstituted Complex Homo sapiens
147 GART 2618
Co-fractionation Homo sapiens
148 RBM22 55696
Proximity Label-MS Homo sapiens
149 ATG5 9474
Proximity Label-MS Homo sapiens
150 DHRS7 51635
Proximity Label-MS Homo sapiens
151 KIAA0020 9933
Proximity Label-MS Homo sapiens
152 GJA1 2697
Affinity Capture-MS Homo sapiens
153 KCTD10 83892
Affinity Capture-MS Homo sapiens
154 PPIL4  
Proximity Label-MS Homo sapiens
155 BTF3 689
Affinity Capture-MS Homo sapiens
156 ALDH2 217
Proximity Label-MS Homo sapiens
157 SRPR 6734
Proximity Label-MS Homo sapiens
158 NUP153 9972
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
159 CNP 1267
Proximity Label-MS Homo sapiens
160 ROCK2 9475
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
161 ANXA6 309
Proximity Label-MS Homo sapiens
162 FYCO1 79443
Affinity Capture-MS Homo sapiens
163 PSIP1 11168
Proximity Label-MS Homo sapiens
164 WTAP 9589
Affinity Capture-MS Homo sapiens
165 PGK1 5230
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
166 B3GNT2 10678
Affinity Capture-MS Homo sapiens
167 DIAPH1 1729
Co-fractionation Homo sapiens
168 YARS2  
Proximity Label-MS Homo sapiens
169 RRP12 23223
Proximity Label-MS Homo sapiens
170 PRC1 9055
Affinity Capture-MS Homo sapiens
171 NPM1 4869
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
172 SRRM2 23524
Affinity Capture-MS Homo sapiens
173 NUP93 9688
Proximity Label-MS Homo sapiens
174 OBSL1 23363
Affinity Capture-MS Homo sapiens
175 PLCG1 5335
Co-fractionation Homo sapiens
176 Cenpe  
Affinity Capture-MS Mus musculus
177 SUN2 25777
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
178 VCAM1 7412
Affinity Capture-MS Homo sapiens
179 LSG1  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
180 NAGK 55577
Proximity Label-MS Homo sapiens
181 WIZ 58525
Proximity Label-MS Homo sapiens
182 CUL1 8454
Proximity Label-MS Homo sapiens
183 USP7 7874
Affinity Capture-MS Homo sapiens
184 FANCD2  
Affinity Capture-MS Homo sapiens
185 GSK3B 2932
Proximity Label-MS Homo sapiens
186 TMEM201 199953
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
187 LMAN1 3998
Proximity Label-MS Homo sapiens
188 GTF2I 2969
Co-fractionation Homo sapiens
189 ALDH16A1 126133
Proximity Label-MS Homo sapiens
190 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
191 NPC1 4864
Proximity Label-MS Homo sapiens
192 UNCX  
Cross-Linking-MS (XL-MS) Homo sapiens
193 WHSC1 7468
Proximity Label-MS Homo sapiens
194 TEAD3  
Proximity Label-MS Homo sapiens
195 PSMD14 10213
Affinity Capture-MS Homo sapiens
196 CFDP1  
Proximity Label-MS Homo sapiens
197 CDKAL1  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
198 SNRPD1 6632
Proximity Label-MS Homo sapiens
199 TNPO3 23534
Proximity Label-MS Homo sapiens
200 REXO4  
Proximity Label-MS Homo sapiens
201 TEAD2  
Proximity Label-MS Homo sapiens
202 GAPDH 2597
Affinity Capture-MS Homo sapiens
203 CHORDC1 26973
Affinity Capture-MS Homo sapiens
204 RFC2 5982
Proximity Label-MS Homo sapiens
205 STX5 6811
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
206 ERMP1 79956
Proximity Label-MS Homo sapiens
207 MEX3A  
Affinity Capture-RNA Homo sapiens
208 CCBL2 56267
Proximity Label-MS Homo sapiens
209 CYLD  
Affinity Capture-MS Homo sapiens
210 GPATCH11  
Proximity Label-MS Homo sapiens
211 OGT 8473
Reconstituted Complex Homo sapiens
212 EGF 1950
Two-hybrid Homo sapiens
213 TPX2  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
214 PRDX6 9588
Affinity Capture-MS Homo sapiens
215 PER2  
Proximity Label-MS Homo sapiens
216 RPN2 6185
Proximity Label-MS Homo sapiens
217 RAB7A 7879
Proximity Label-MS Homo sapiens
218 EMC8 10328
Proximity Label-MS Homo sapiens
219 RAB5A 5868
Proximity Label-MS Homo sapiens
220 ILKAP 80895
Proximity Label-MS Homo sapiens
221 UBXN7 26043
Proximity Label-MS Homo sapiens
222 ANXA8L1 728113
Proximity Label-MS Homo sapiens
223 PPA1 5464
Affinity Capture-MS Homo sapiens
224 BET1 10282
Proximity Label-MS Homo sapiens
225 UBE2L6 9246
Affinity Capture-MS Homo sapiens
226 SREBF1 6720
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
227 C1orf52  
Proximity Label-MS Homo sapiens
228 EGFR 1956
Affinity Capture-MS Homo sapiens
229 ITPRIP  
Proximity Label-MS Homo sapiens
230 FUS 2521
Affinity Capture-MS Homo sapiens
231 MORF4L1  
Affinity Capture-MS Homo sapiens
232 GHITM 27069
Proximity Label-MS Homo sapiens
233 RP9  
Proximity Label-MS Homo sapiens
234 DUSP13  
Two-hybrid Homo sapiens
235 PPIL3 53938
Affinity Capture-MS Homo sapiens
236 CDK2 1017
Affinity Capture-MS Homo sapiens
237 RAPGEF2 9693
Affinity Capture-MS Homo sapiens
238 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
239 ARHGEF5  
Affinity Capture-MS Homo sapiens
240 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
241 RAI1 10743
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
242 VRK2 7444
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
243 SNW1 22938
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
244 DDRGK1 65992
Proximity Label-MS Homo sapiens
245 BMI1  
Affinity Capture-MS Homo sapiens
246 PGAM1 5223
Affinity Capture-MS Homo sapiens
247 TKFC 26007
Proximity Label-MS Homo sapiens
248 TMEM209 84928
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
249 LEMD3  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
250 MCM3AP  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
251 HVCN1 84329
Affinity Capture-MS Homo sapiens
252 SUN1 23353
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
253 RRM2 6241
Proximity Label-MS Homo sapiens
254 PARP1 142
Co-fractionation Homo sapiens
255 Ewsr1 14030
Two-hybrid Mus musculus
256 GDI2 2665
Affinity Capture-MS Homo sapiens
257 TP53 7157
Affinity Capture-MS Homo sapiens
258 PGRMC1 10857
Proximity Label-MS Homo sapiens
259 TMEM214 54867
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
260 GOSR1 9527
Proximity Label-MS Homo sapiens
261 SENP6  
Proximity Label-MS Homo sapiens
262 ARF5 381
Affinity Capture-MS Homo sapiens
263 RIF1  
Proximity Label-MS Homo sapiens
264 HLTF  
Proximity Label-MS Homo sapiens
265 KNOP1 400506
Proximity Label-MS Homo sapiens
266 DNAAF5 54919
Proximity Label-MS Homo sapiens
267 CMTR1 23070
Proximity Label-MS Homo sapiens
268 RNF20 56254
Co-fractionation Homo sapiens
269 THEM6  
Proximity Label-MS Homo sapiens
270 SHMT2 6472
Affinity Capture-RNA Homo sapiens
271 ZNF281  
Proximity Label-MS Homo sapiens
272 ZKSCAN1  
Affinity Capture-MS Homo sapiens
273 RBBP9 10741
Cross-Linking-MS (XL-MS) Homo sapiens
274 MMGT1 93380
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
275 ESR1  
Affinity Capture-MS Homo sapiens
276 AUP1 550
Proximity Label-MS Homo sapiens
277 ZNF195  
Affinity Capture-MS Homo sapiens
278 PLD3 23646
Proximity Label-MS Homo sapiens
279 CDV3 55573
Affinity Capture-MS Homo sapiens
280 KRT38 8687
Affinity Capture-MS Homo sapiens
281 DHX38 9785
Proximity Label-MS Homo sapiens
282 PPFIA4  
Cross-Linking-MS (XL-MS) Homo sapiens
283 CXorf56  
Proximity Label-MS Homo sapiens
284 TMEM109 79073
Proximity Label-MS Homo sapiens
285 GOT1 2805
Proximity Label-MS Homo sapiens
286 YKT6 10652
Proximity Label-MS Homo sapiens
287 BCCIP 56647
Proximity Label-MS Homo sapiens
288 C1QBP 708
Co-fractionation Homo sapiens
289 RNF113A 7737
Proximity Label-MS Homo sapiens
290 MAST3  
Affinity Capture-MS Homo sapiens
291 PRMT1 3276
Affinity Capture-MS Homo sapiens
292 ALKBH5 54890
Proximity Label-MS Homo sapiens
293 TIMM13 26517
Proximity Label-MS Homo sapiens
294 ATP13A1 57130
Proximity Label-MS Homo sapiens
295 NDUFB4 4710
Proximity Label-MS Homo sapiens
296 CCDC94  
Proximity Label-MS Homo sapiens
297 CLCN7 1186
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
298 RAB1A 5861
Co-fractionation Homo sapiens
299 DNAJC8 22826
Affinity Capture-MS Homo sapiens
300 DHCR24 1718
Proximity Label-MS Homo sapiens
301 NAPA 8775
Proximity Label-MS Homo sapiens
302 MTX1 4580
Proximity Label-MS Homo sapiens
303 MME 4311
Affinity Capture-MS Homo sapiens
304 GPC1 2817
Proximity Label-MS Homo sapiens
305 HIST1H2BJ 8970
Cross-Linking-MS (XL-MS) Homo sapiens
306 BNIP1 662
Proximity Label-MS Homo sapiens
307 NMI  
Co-fractionation Homo sapiens
308 EFTUD1 79631
Co-fractionation Homo sapiens
309 EFCAB5 374786
Cross-Linking-MS (XL-MS) Homo sapiens
310 PSMD10 5716
Co-fractionation Homo sapiens
311 PTPN1 5770
Proximity Label-MS Homo sapiens
312 IQGAP2 10788
Cross-Linking-MS (XL-MS) Homo sapiens
313 ZNF239  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
314 PCGF2 7703
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
315 ZMAT2  
Proximity Label-MS Homo sapiens
316 SCO1  
Proximity Label-MS Homo sapiens
317 TEX264 51368
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
318 XPNPEP1 7511
Proximity Label-MS Homo sapiens
319 TXNDC17 84817
Affinity Capture-MS Homo sapiens
320 MCM2 4171
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
321 TM9SF2 9375
Proximity Label-MS Homo sapiens
322 SENP1  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
323 KDM2A  
Proximity Label-MS Homo sapiens
324 NFE2L2 4780
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
325 ZNF148  
Proximity Label-MS Homo sapiens
326 SPTLC1 10558
Proximity Label-MS Homo sapiens
327 Tagap  
Affinity Capture-MS Mus musculus
328 SSR1 6745
Proximity Label-MS Homo sapiens
329 LINC00240  
Affinity Capture-MS Homo sapiens
330 PSME1 5720
Co-fractionation Homo sapiens
331 MCM6 4175
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
332 ITGA4 3676
Affinity Capture-MS Homo sapiens
333 CCDC47 57003
Proximity Label-MS Homo sapiens
334 RGPD6  
Proximity Label-MS Homo sapiens
335 B4GALT1 2683
Proximity Label-MS Homo sapiens
336 CALR 811
Affinity Capture-MS Homo sapiens
337 LCLAT1 253558
Proximity Label-MS Homo sapiens
338 METTL7A 25840
Proximity Label-MS Homo sapiens
339 KIAA0196 9897
Co-fractionation Homo sapiens
340 EEA1 8411
Cross-Linking-MS (XL-MS) Homo sapiens
341 Arhgap1 228359
Affinity Capture-MS Mus musculus
342 SERPINB9 5272
Proximity Label-MS Homo sapiens
343 NUP155 9631
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
344 UNC13D 201294
Two-hybrid Homo sapiens
345 SLC30A1 7779
Proximity Label-MS Homo sapiens
346 PTGES2 80142
Proximity Label-MS Homo sapiens
347 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
348 NSUN2 54888
Co-fractionation Homo sapiens
349 LMNA 4000
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
350 CERS2 29956
Proximity Label-MS Homo sapiens
351 IRAK1  
Affinity Capture-MS Homo sapiens
352 WDR70 55100
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
353 PINX1  
Proximity Label-MS Homo sapiens
354 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
355 COPE 11316
Affinity Capture-MS Homo sapiens
356 ARL6IP5 10550
Proximity Label-MS Homo sapiens
357 CNOT4 4850
Affinity Capture-MS Homo sapiens
358 PLOD2 5352
Co-fractionation Homo sapiens
359 PPIL2  
Proximity Label-MS Homo sapiens
360 LRWD1  
Proximity Label-MS Homo sapiens
361 CHMP4B 128866
Affinity Capture-MS Homo sapiens
362 RAN 5901
Affinity Capture-MS Homo sapiens
363 NTRK1 4914
Affinity Capture-MS Homo sapiens
364 DEK 7913
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
365 TTLL1  
Cross-Linking-MS (XL-MS) Homo sapiens
366 CARM1 10498
Proximity Label-MS Homo sapiens
367 PPME1 51400
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
368 KIAA0391  
Proximity Label-MS Homo sapiens
369 RPN1 6184
Proximity Label-MS Homo sapiens
370 COA7  
Co-fractionation Homo sapiens
371 COPS3 8533
Proximity Label-MS Homo sapiens
372 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
373 HNRNPA3 220988
Co-fractionation Homo sapiens
374 DNTTIP2  
Proximity Label-MS Homo sapiens
375 CFAP74  
Cross-Linking-MS (XL-MS) Homo sapiens
376 ALX3  
Affinity Capture-MS Homo sapiens
377 SLX4  
Affinity Capture-MS Homo sapiens
378 OLA1 29789
Proximity Label-MS Homo sapiens
379 FAM170A  
Affinity Capture-MS Homo sapiens
380 PGLS 25796
Proximity Label-MS Homo sapiens
381 AHCY 191
Co-fractionation Homo sapiens
382 THUMPD1 55623
Proximity Label-MS Homo sapiens
383 METTL14  
Affinity Capture-MS Homo sapiens
384 DNAJB12 54788
Proximity Label-MS Homo sapiens
385 MSH2 4436
Proximity Label-MS Homo sapiens
386 BAZ1B 9031
Proximity Label-MS Homo sapiens
387 WRNIP1 56897
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
388 ECT2 1894
Affinity Capture-MS Homo sapiens
389 STAC  
Two-hybrid Homo sapiens
390 LMNB2 84823
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
391 CA5A  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
392 STIM1 6786
Proximity Label-MS Homo sapiens
393 FBXO6 26270
Affinity Capture-MS Homo sapiens
394 KRTAP10-3  
Two-hybrid Homo sapiens
395 PDCD11 22984
Proximity Label-MS Homo sapiens
396 PUS7 54517
Proximity Label-MS Homo sapiens
397 RFC1 5981
Proximity Label-MS Homo sapiens
398 SPTAN1 6709
Co-fractionation Homo sapiens
399 USE1 55850
Proximity Label-MS Homo sapiens
400 DNAJC10 54431
Proximity Label-MS Homo sapiens
401 DNAJC3 5611
Co-fractionation Homo sapiens
402 ACTB 60
Co-fractionation Homo sapiens
403 RANBP1 5902
Affinity Capture-MS Homo sapiens
404 HSPD1 3329
Affinity Capture-MS Homo sapiens
405 TSR1 55720
Proximity Label-MS Homo sapiens
406 ROCK1 6093
Co-fractionation Homo sapiens
407 FOXK1 221937
Co-fractionation Homo sapiens
408 AKAP1 8165
Proximity Label-MS Homo sapiens
409 UBE2J1 51465
Proximity Label-MS Homo sapiens
410 TBX3 6926
Affinity Capture-MS Homo sapiens
411 ZRANB2 9406
Proximity Label-MS Homo sapiens
412 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
413 MAP2K6 5608
Proximity Label-MS Homo sapiens
414 ALDH3A2 224
Proximity Label-MS Homo sapiens
415 VASH2  
Cross-Linking-MS (XL-MS) Homo sapiens
416 ZNF384  
Proximity Label-MS Homo sapiens
417 SLC25A6 293
Co-fractionation Homo sapiens
418 TOR1AIP2 163590
Proximity Label-MS Homo sapiens
419 THUMPD3 25917
Co-fractionation Homo sapiens
420 CWC27 10283
Proximity Label-MS Homo sapiens
421 FOLR1 2348
Affinity Capture-MS Homo sapiens
422 MCM5 4174
Affinity Capture-MS Homo sapiens
423 RPA1 6117
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
424 PDHA1 5160
Affinity Capture-MS Homo sapiens
425 HNRNPM 4670
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
426 PDCD10 11235
Proximity Label-MS Homo sapiens
427 ZNF280C  
Proximity Label-MS Homo sapiens
428 PCNA 5111
Affinity Capture-Western Homo sapiens
429 GZMB  
Biochemical Activity Homo sapiens
430 TBRG4 9238
Proximity Label-MS Homo sapiens
431 FGFR1OP2  
Affinity Capture-MS Homo sapiens
432 ZNRF4  
Affinity Capture-MS Homo sapiens
433 FLNA 2316
Two-hybrid Homo sapiens
434 TRAPPC3 27095
Proximity Label-MS Homo sapiens
435 METTL3  
Affinity Capture-MS Homo sapiens
436 C14orf166 51637
Proximity Label-MS Homo sapiens
437 STT3B 201595
Proximity Label-MS Homo sapiens
438 ARHGAP24  
Affinity Capture-MS Homo sapiens
439 RSF1  
Proximity Label-MS Homo sapiens
440 CAV1 857
Proximity Label-MS Homo sapiens
441 GPKOW  
Proximity Label-MS Homo sapiens
442 CDK11A 728642
Affinity Capture-MS Homo sapiens
443 TIMM44 10469
Proximity Label-MS Homo sapiens
444 ILDR2  
Affinity Capture-MS Homo sapiens
445 SLFN11 91607
Affinity Capture-MS Homo sapiens
446 HSD17B11 51170
Proximity Label-MS Homo sapiens
447 PSMD6 9861
Co-fractionation Homo sapiens
448 VAPA 9218
Proximity Label-MS Homo sapiens
449 SYCE1  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
450 PPIE 10450
Affinity Capture-MS Homo sapiens
451 POM121  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
452 DNAJC25 548645
Proximity Label-MS Homo sapiens
453 INCENP 3619
Proximity Label-MS Homo sapiens
454 CFL1 1072
Affinity Capture-MS Homo sapiens
455 PPP1CC 5501
Affinity Capture-MS Homo sapiens
456 KIAA1429 25962
Affinity Capture-MS Homo sapiens
457 PPCS 79717
Proximity Label-MS Homo sapiens
458 EIF4ENIF1 56478
Two-hybrid Homo sapiens
459 TOP2A 7153
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
460 ALOX12 239
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
461 TSC1 7248
Cross-Linking-MS (XL-MS) Homo sapiens
462 SUCLA2 8803
Proximity Label-MS Homo sapiens
463 PITPNB 23760
Proximity Label-MS Homo sapiens
464 FBXW7  
Affinity Capture-MS Homo sapiens
465 TOR1AIP1 26092
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
466 NARF 26502
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
467 MDH1 4190
Affinity Capture-MS Homo sapiens
468 ZNF512B  
Proximity Label-MS Homo sapiens
469 ZSCAN21  
Proximity Label-MS Homo sapiens
470 ABCE1 6059
Affinity Capture-MS Homo sapiens
471 TEAD1  
Proximity Label-MS Homo sapiens
472 PGRMC2 10424
Proximity Label-MS Homo sapiens
473 EED  
Affinity Capture-MS Homo sapiens
474 RRP8  
Affinity Capture-MS Homo sapiens
475 PMS2  
Co-fractionation Homo sapiens
476 PDE6D 5147
Affinity Capture-MS Homo sapiens
477 RAB35 11021
Proximity Label-MS Homo sapiens
478 MYCN  
Affinity Capture-MS Homo sapiens
479 ALG5 29880
Proximity Label-MS Homo sapiens
480 ATP6AP1 537
Proximity Label-MS Homo sapiens
481 TMX3 54495
Proximity Label-MS Homo sapiens
482 CTCF  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
483 METTL13 51603
Proximity Label-MS Homo sapiens
484 RB1 5925
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
485 LRRC59 55379
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
486 PRPF6 24148
Two-hybrid Homo sapiens
487 POM121C  
Proximity Label-MS Homo sapiens
488 LMNB1 4001
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
489 BRIP1  
Proximity Label-MS Homo sapiens
490 MRPL54  
Co-fractionation Homo sapiens
491 EMD 2010
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
492 MRPS26 64949
Two-hybrid Homo sapiens
493 TBL2 26608
Proximity Label-MS Homo sapiens
494 PIAS4  
Proximity Label-MS Homo sapiens
495 TXN 7295
Co-fractionation Homo sapiens
496 NONO 4841
Co-fractionation Homo sapiens
497 UBE2I 7329
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
498 FAM118B  
Co-fractionation Homo sapiens
499 CYB5A 1528
Proximity Label-MS Homo sapiens
500 VCP 7415
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
501 LEMD2 221496
Proximity Label-MS Homo sapiens
502 SYNC  
Affinity Capture-MS Homo sapiens
503 PIAS2  
Proximity Label-MS Homo sapiens
504 ERP29 10961
Affinity Capture-MS Homo sapiens
505 MOGS 7841
Proximity Label-MS Homo sapiens
506 Ube2i  
Two-hybrid Mus musculus
507 ELOVL5 60481
Proximity Label-MS Homo sapiens
508 PRKACB 5567
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
509 SLC33A1 9197
Proximity Label-MS Homo sapiens
510 EEF1D 1936
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
511 TPR 7175
Proximity Label-MS Homo sapiens
512 FAM133B 257415
Cross-Linking-MS (XL-MS) Homo sapiens
513 SEC63 11231
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
514 PKMYT1  
Proximity Label-MS Homo sapiens
515 RAP1GDS1 5910
Proximity Label-MS Homo sapiens
516 BMS1  
Proximity Label-MS Homo sapiens
517 COPS2 9318
Affinity Capture-MS Homo sapiens
518 HIST1H3A 8350
Cross-Linking-MS (XL-MS) Homo sapiens
519 VAPB 9217
Proximity Label-MS Homo sapiens
520 CUL3 8452
Affinity Capture-MS Homo sapiens
521 PRKCA 5578
Protein-peptide Homo sapiens
522 RAB34 83871
Proximity Label-MS Homo sapiens
523 HMOX2 3163
Proximity Label-MS Homo sapiens
524 CTNNB1 1499
Affinity Capture-Western Homo sapiens
525 KCTD12 115207
Co-fractionation Homo sapiens
526 NSD1  
Proximity Label-MS Homo sapiens
527 Rbm14  
Two-hybrid Mus musculus
528 MRGBP  
Affinity Capture-MS Homo sapiens
529 MCM4 4173
Co-fractionation Homo sapiens
530 BBX 56987
Proximity Label-MS Homo sapiens
531 NXF1 10482
Affinity Capture-RNA Homo sapiens
532 AURKB 9212
Affinity Capture-MS Homo sapiens
533 MLIP  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
534 PRKACA 5566
Proximity Label-MS Homo sapiens
535 ADD1 118
Co-fractionation Homo sapiens
536 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
537 DIS3 22894
Proximity Label-MS Homo sapiens
538 KAT5  
Two-hybrid Homo sapiens
539 SF3B3 23450
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
540 CACTIN  
Proximity Label-MS Homo sapiens
541 PLEKHG3 26030
Affinity Capture-MS Homo sapiens
542 TTC39A 22996
Affinity Capture-MS Homo sapiens
543 BRD3 8019
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
544 CCDC8  
Affinity Capture-MS Homo sapiens
545 PKP3 11187
Proximity Label-MS Homo sapiens
546 H2AFX 3014
Affinity Capture-MS Homo sapiens
547 LBR 3930
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
548 UGP2 7360
Cross-Linking-MS (XL-MS) Homo sapiens
549 KIAA0430  
Affinity Capture-MS Homo sapiens
550 CLIC1 1192
Affinity Capture-MS Homo sapiens
551 SIRT6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
552 AKR1B1 231
Affinity Capture-MS Homo sapiens
553 NUP133 55746
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
554 SVIL 6840
Two-hybrid Homo sapiens
555 SRRM1 10250
Affinity Capture-MS Homo sapiens
556 MRPS2 51116
Proximity Label-MS Homo sapiens
557 SAP130  
Co-fractionation Homo sapiens
558 PDCD6 10016
Proximity Label-MS Homo sapiens
559 SMURF1 57154
Biochemical Activity Homo sapiens
560 CAGE1 285782
Cross-Linking-MS (XL-MS) Homo sapiens
561 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
562 PRR14  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
563 NUP35 129401
Proximity Label-MS Homo sapiens
564 NUP98 4928
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
565 WDR18 57418
Co-fractionation Homo sapiens
566 RBFOX2 23543
Two-hybrid Homo sapiens
567 NUP50 10762
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
568 NUP107 57122
Proximity Label-MS Homo sapiens
569 PDLIM5 10611
Co-fractionation Homo sapiens
570 ING1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
571 RETSAT 54884
Proximity Label-MS Homo sapiens
572 MOV10 4343
Affinity Capture-RNA Homo sapiens
573 SLC5A8 160728
Affinity Capture-MS Homo sapiens
574 PINK1  
Affinity Capture-MS Homo sapiens
575 GTF2E1 2960
Proximity Label-MS Homo sapiens
576 XRCC6 2547
Proximity Label-MS Homo sapiens
577 EIF5A 1984
Affinity Capture-MS Homo sapiens
578 DNAJC1 64215
Proximity Label-MS Homo sapiens
579 HNRNPU 3192
Co-fractionation Homo sapiens
580 LIMK2 3985
Affinity Capture-MS Homo sapiens
581 CDC5L 988
Affinity Capture-MS Homo sapiens
582 CNDP2 55748
Co-fractionation Homo sapiens
583 PARN  
Proximity Label-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here