Gene description for CAMLG
Gene name calcium modulating ligand
Gene symbol CAMLG
Other names/aliases CAML
Species Homo sapiens
 Database cross references - CAMLG
ExoCarta ExoCarta_819
Entrez Gene 819
HGNC 1471
MIM 601118
UniProt P49069  
 CAMLG identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for CAMLG
Molecular Function
    protein binding GO:0005515 IPI
    cell adhesion molecule binding GO:0050839 IEA
Biological Process
    defense response GO:0006952 TAS
    viral process GO:0016032 IEA
    signal transduction GO:0007165 TAS
    epidermal growth factor receptor signaling pathway GO:0007173 IEA
    receptor recycling GO:0001881 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IDA
    endoplasmic reticulum GO:0005783 IDA
 Experiment description of studies that identified CAMLG in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for CAMLG
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PPIB 5479
Two-hybrid Homo sapiens
2 EGFR 1956
Affinity Capture-Western Homo sapiens
3 TNFRSF13B  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which CAMLG is involved
No pathways found





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