Gene description for RAB4A
Gene name RAB4A, member RAS oncogene family
Gene symbol RAB4A
Other names/aliases HRES-1
HRES-1/RAB4
HRES1
RAB4
Species Homo sapiens
 Database cross references - RAB4A
ExoCarta ExoCarta_5867
Vesiclepedia VP_5867
Entrez Gene 5867
HGNC 9781
MIM 179511
UniProt P20338  
 RAB4A identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Keratinocytes 19530224    
Keratinocytes 19530224    
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for RAB4A
Molecular Function
    GTPase activity GO:0003924 IBA
    GTPase activity GO:0003924 IDA
    G protein activity GO:0003925 IEA
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IBA
    GTP binding GO:0005525 IDA
    GDP binding GO:0019003 IDA
Biological Process
    vesicle-mediated transport GO:0016192 IBA
    antigen processing and presentation GO:0019882 IMP
    regulation of endocytosis GO:0030100 IBA
    Rab protein signal transduction GO:0032482 IEA
    neurotransmitter receptor transport postsynaptic membrane to endosome GO:0098968 IEA
    vesicle-mediated transport in synapse GO:0099003 IEA
Subcellular Localization
    cytoplasmic vesicle membrane GO:0030659 TAS
    early endosome membrane GO:0031901 TAS
    vesicle GO:0031982 IDA
    insulin-responsive compartment GO:0032593 IBA
    perinuclear region of cytoplasm GO:0048471 IDA
    recycling endosome membrane GO:0055038 IEA
    extracellular exosome GO:0070062 IDA
    postsynaptic recycling endosome GO:0098837 IBA
    glutamatergic synapse GO:0098978 IEA
 Experiment description of studies that identified RAB4A in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 189
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
6
Experiment ID 190
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
9
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 194
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 195
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RAB4A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ITGB1 3688
Proximity Label-MS Homo sapiens
2 ARHGAP1 392
Proximity Label-MS Homo sapiens
3 CCDC132 55610
Proximity Label-MS Homo sapiens
4 JPH1 56704
Proximity Label-MS Homo sapiens
5 GAK 2580
Proximity Label-MS Homo sapiens
6 VPS13C 54832
Proximity Label-MS Homo sapiens
7 MON2 23041
Proximity Label-MS Homo sapiens
8 SMPD4 55627
Proximity Label-MS Homo sapiens
9 GDI1 2664
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 HSPH1 10808
Affinity Capture-MS Homo sapiens
11 ABCD3 5825
Proximity Label-MS Homo sapiens
12 PIK3C3 5289
Proximity Label-MS Homo sapiens
13 VPS13D 55187
Proximity Label-MS Homo sapiens
14 AP1AR 55435
Proximity Label-MS Homo sapiens
15 ZC3HAV1 56829
Proximity Label-MS Homo sapiens
16 GRPR  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 ARFGEF2 10564
Proximity Label-MS Homo sapiens
18 SLC6A15 55117
Proximity Label-MS Homo sapiens
19 ZFYVE9  
Proximity Label-MS Homo sapiens
20 TFRC 7037
Proximity Label-MS Homo sapiens
21 STX12 23673
Proximity Label-MS Homo sapiens
22 TMEM87A 25963
Proximity Label-MS Homo sapiens
23 EXOC3 11336
Proximity Label-MS Homo sapiens
24 NOTCH2 4853
Proximity Label-MS Homo sapiens
25 CAMLG 819
Proximity Label-MS Homo sapiens
26 RABGEF1 27342
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 SENP2 59343
Proximity Label-MS Homo sapiens
28 RAB14 51552
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
29 VPS51 738
Proximity Label-MS Homo sapiens
30 ATP7B 540
Proximity Label-MS Homo sapiens
31 EFR3B  
Proximity Label-MS Homo sapiens
32 EREG  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 PDXDC1 23042
Proximity Label-MS Homo sapiens
34 CLCC1 23155
Proximity Label-MS Homo sapiens
35 WDR45  
Proximity Label-MS Homo sapiens
36 GORASP2 26003
Proximity Label-MS Homo sapiens
37 HACE1 57531
Reconstituted Complex Homo sapiens
38 RAB4B 53916
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 FLOT2 2319
Proximity Label-MS Homo sapiens
40 VPS18 57617
Proximity Label-MS Homo sapiens
41 LRP8 7804
Proximity Label-MS Homo sapiens
42 TMF1 7110
Proximity Label-MS Homo sapiens
43 DST 667
Proximity Label-MS Homo sapiens
44 ANO6 196527
Proximity Label-MS Homo sapiens
45 HACE1  
Reconstituted Complex Bos taurus
46 FAM83B  
Proximity Label-MS Homo sapiens
47 LRP4 4038
Proximity Label-MS Homo sapiens
48 VAMP8 8673
Proximity Label-MS Homo sapiens
49 DHCR7 1717
Proximity Label-MS Homo sapiens
50 CDCA3 83461
Proximity Label-MS Homo sapiens
51 NBEA  
Proximity Label-MS Homo sapiens
52 SCAMP1 9522
Proximity Label-MS Homo sapiens
53 BCAP31 10134
Proximity Label-MS Homo sapiens
54 TMEM199  
Proximity Label-MS Homo sapiens
55 LMTK2 22853
Proximity Label-MS Homo sapiens
56 PIK3C2B 5287
Proximity Label-MS Homo sapiens
57 MIA3 375056
Proximity Label-MS Homo sapiens
58 KIAA1467 57613
Proximity Label-MS Homo sapiens
59 RPA3 6119
Proximity Label-MS Homo sapiens
60 UHRF1BP1 54887
Proximity Label-MS Homo sapiens
61 RPL35A 6165
Affinity Capture-MS Homo sapiens
62 FAM21C 253725
Proximity Label-MS Homo sapiens
63 COLEC12 81035
Proximity Label-MS Homo sapiens
64 WLS 79971
Proximity Label-MS Homo sapiens
65 KIDINS220 57498
Proximity Label-MS Homo sapiens
66 SCCPDH 51097
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 KCNA5  
Co-localization Homo sapiens
68 GOLGB1 2804
Proximity Label-MS Homo sapiens
69 FLVCR1 28982
Proximity Label-MS Homo sapiens
70 GGA3 23163
Proximity Label-MS Homo sapiens
71 CHML  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 PIKFYVE 200576
Proximity Label-MS Homo sapiens
73 TMEM57  
Proximity Label-MS Homo sapiens
74 SCYL3 57147
Proximity Label-MS Homo sapiens
75 FCGRT 2217
Proximity Label-MS Homo sapiens
76 ITPR3 3710
Proximity Label-MS Homo sapiens
77 ARFIP2 23647
Proximity Label-MS Homo sapiens
78 TRIP11 9321
Proximity Label-MS Homo sapiens
79 RAB11FIP1 80223
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
80 VAMP7 6845
Proximity Label-MS Homo sapiens
81 RABL3 285282
Proximity Label-MS Homo sapiens
82 HM13 81502
Proximity Label-MS Homo sapiens
83 NDC1 55706
Proximity Label-MS Homo sapiens
84 CLTA 1211
Affinity Capture-MS Homo sapiens
85 EPHA2 1969
Proximity Label-MS Homo sapiens
86 VANGL1 81839
Proximity Label-MS Homo sapiens
87 SNX29  
Proximity Label-MS Homo sapiens
88 SCAMP3 10067
Proximity Label-MS Homo sapiens
89 RPS6KA1 6195
Affinity Capture-MS Homo sapiens
90 CTNND1 1500
Proximity Label-MS Homo sapiens
91 ACY1 95
Affinity Capture-MS Homo sapiens
92 KIF16B 55614
Proximity Label-MS Homo sapiens
93 TBC1D12 23232
Proximity Label-MS Homo sapiens
94 RPA2 6118
Proximity Label-MS Homo sapiens
95 SRPR 6734
Proximity Label-MS Homo sapiens
96 FAM21A 387680
Proximity Label-MS Homo sapiens
97 VAMP2 6844
Proximity Label-MS Homo sapiens
98 Gdi2 14569
Affinity Capture-Western Mus musculus
99 RABGAP1L 9910
Proximity Label-MS Homo sapiens
100 VPS54  
Proximity Label-MS Homo sapiens
101 AFTPH  
Proximity Label-MS Homo sapiens
102 KCTD7 154881
Two-hybrid Homo sapiens
103 KIF13B 23303
Proximity Label-MS Homo sapiens
104 VANGL2  
Proximity Label-MS Homo sapiens
105 WDR41  
Proximity Label-MS Homo sapiens
106 DIAPH2  
Proximity Label-MS Homo sapiens
107 WDR7 23335
Proximity Label-MS Homo sapiens
108 STEAP3 55240
Proximity Label-MS Homo sapiens
109 GGA1 26088
Proximity Label-MS Homo sapiens
110 NCOA7  
Proximity Label-MS Homo sapiens
111 RAB4A  
Affinity Capture-MS Bos taurus
Affinity Capture-Western Bos taurus
112 FGFR1 2260
Affinity Capture-MS Homo sapiens
113 AP4E1  
Proximity Label-MS Homo sapiens
114 LMAN1 3998
Proximity Label-MS Homo sapiens
115 KIAA1715 80856
Proximity Label-MS Homo sapiens
116 ATG2A  
Proximity Label-MS Homo sapiens
117 CHMP7 91782
Proximity Label-MS Homo sapiens
118 SLC1A5 6510
Proximity Label-MS Homo sapiens
119 VPS45 11311
Proximity Label-MS Homo sapiens
120 RUFY1 80230
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
121 EXOC4 60412
Proximity Label-MS Homo sapiens
122 SNAP47 116841
Proximity Label-MS Homo sapiens
123 RABEP2 511736
Affinity Capture-MS Bos taurus
Affinity Capture-Western Bos taurus
124 CDKAL1  
Proximity Label-MS Homo sapiens
125 PREB 10113
Proximity Label-MS Homo sapiens
126 PTTG1IP 754
Two-hybrid Homo sapiens
127 STX5 6811
Proximity Label-MS Homo sapiens
128 SLC12A4 6560
Proximity Label-MS Homo sapiens
129 RBSN 64145
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
130 GOLGA5 9950
Proximity Label-MS Homo sapiens
131 KIF3B 9371
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
132 KIF1B 23095
Proximity Label-MS Homo sapiens
133 MXRA7 439921
Proximity Label-MS Homo sapiens
134 RAB5A 5868
Co-purification Homo sapiens
135 ADCY9 115
Proximity Label-MS Homo sapiens
136 DMXL1 1657
Proximity Label-MS Homo sapiens
137 EGFR 1956
Proximity Label-MS Homo sapiens
138 ARFIP1 27236
Proximity Label-MS Homo sapiens
139 PLEKHA5 54477
Proximity Label-MS Homo sapiens
140 SCYL2 55681
Proximity Label-MS Homo sapiens
141 CD226 10666
Affinity Capture-MS Homo sapiens
142 FAM91A1 157769
Proximity Label-MS Homo sapiens
143 SLC3A2 6520
Proximity Label-MS Homo sapiens
144 SLC12A7 10723
Proximity Label-MS Homo sapiens
145 VRK2 7444
Proximity Label-MS Homo sapiens
146 AHNAK2 113146
Proximity Label-MS Homo sapiens
147 SLC12A6 9990
Proximity Label-MS Homo sapiens
148 LEMD3  
Proximity Label-MS Homo sapiens
149 CPNE8 144402
Proximity Label-MS Homo sapiens
150 OSBPL8 114882
Proximity Label-MS Homo sapiens
151 SYNRG 11276
Proximity Label-MS Homo sapiens
152 DENND4C 55667
Proximity Label-MS Homo sapiens
153 SUN1 23353
Proximity Label-MS Homo sapiens
154 UHRF1BP1L 23074
Proximity Label-MS Homo sapiens
155 SLC38A2 54407
Proximity Label-MS Homo sapiens
156 TRIM13  
Proximity Label-MS Homo sapiens
157 TP53 7157
Two-hybrid Homo sapiens
158 PGRMC1 10857
Proximity Label-MS Homo sapiens
159 VPS13B  
Proximity Label-MS Homo sapiens
160 VTI1A 143187
Proximity Label-MS Homo sapiens
161 SLCO4A1 28231
Proximity Label-MS Homo sapiens
162 TACC1 6867
Proximity Label-MS Homo sapiens
163 NSDHL 50814
Proximity Label-MS Homo sapiens
164 TSC1 7248
Proximity Label-MS Homo sapiens
165 TOR1AIP1 26092
Proximity Label-MS Homo sapiens
166 VPS33A 65082
Proximity Label-MS Homo sapiens
167 KIAA0319L 79932
Proximity Label-MS Homo sapiens
168 DENND4A 10260
Proximity Label-MS Homo sapiens
169 YKT6 10652
Proximity Label-MS Homo sapiens
170 IGF2R 3482
Proximity Label-MS Homo sapiens
171 KIAA1468 57614
Proximity Label-MS Homo sapiens
172 RPS6KC1  
Proximity Label-MS Homo sapiens
173 CKAP4 10970
Proximity Label-MS Homo sapiens
174 AP3D1 8943
Proximity Label-MS Homo sapiens
175 VPS33B 26276
Proximity Label-MS Homo sapiens
176 VPS8 23355
Proximity Label-MS Homo sapiens
177 DYNC1LI1 51143
Two-hybrid Homo sapiens
178 ZNF830  
Two-hybrid Homo sapiens
179 CC2D1A 54862
Proximity Label-MS Homo sapiens
180 MTMR6 9107
Proximity Label-MS Homo sapiens
181 ATP6V1B2 526
Proximity Label-MS Homo sapiens
182 CLCN7 1186
Proximity Label-MS Homo sapiens
183 CD99 4267
Proximity Label-MS Homo sapiens
184 TPD52L2 7165
Proximity Label-MS Homo sapiens
185 KIF13A 63971
Proximity Label-MS Homo sapiens
186 EPB41L5 57669
Proximity Label-MS Homo sapiens
187 GRIPAP1 56850
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
188 SHB 6461
Proximity Label-MS Homo sapiens
189 SYNE2 23224
Proximity Label-MS Homo sapiens
190 PTPN1 5770
Proximity Label-MS Homo sapiens
191 APBB1  
Proximity Label-MS Homo sapiens
192 STX4 6810
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
193 RTN4 57142
Proximity Label-MS Homo sapiens
194 SNX3 8724
Proximity Label-MS Homo sapiens
195 NUMBL 9253
Proximity Label-MS Homo sapiens
196 STX8 9482
Proximity Label-MS Homo sapiens
197 DDRGK1 65992
Proximity Label-MS Homo sapiens
198 SLC31A1 1317
Affinity Capture-MS Homo sapiens
199 CCDC47 57003
Proximity Label-MS Homo sapiens
200 GOLGA4  
Proximity Label-MS Homo sapiens
201 SLC19A1 6573
Proximity Label-MS Homo sapiens
202 INPP5F  
Proximity Label-MS Homo sapiens
203 MAVS 57506
Proximity Label-MS Homo sapiens
204 ESYT2 57488
Proximity Label-MS Homo sapiens
205 GPRC5C 55890
Proximity Label-MS Homo sapiens
206 ATP13A3 79572
Proximity Label-MS Homo sapiens
207 TMEM115 11070
Proximity Label-MS Homo sapiens
208 EXOC5 10640
Two-hybrid Homo sapiens
209 EEA1 8411
Proximity Label-MS Homo sapiens
210 PLEKHA1 59338
Proximity Label-MS Homo sapiens
211 PALD1 27143
Proximity Label-MS Homo sapiens
212 KIAA1217 56243
Proximity Label-MS Homo sapiens
213 ZFYVE16  
Proximity Label-MS Homo sapiens
214 CXADR 1525
Proximity Label-MS Homo sapiens
215 RABEP1 9135
Two-hybrid Homo sapiens
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
216 OCLN 100506658
Proximity Label-MS Homo sapiens
217 PDCD1LG2 80380
Affinity Capture-MS Homo sapiens
218 GOLGA2 2801
Proximity Label-MS Homo sapiens
219 MEMO1 51072
Affinity Capture-MS Homo sapiens
220 NUMB 8650
Proximity Label-MS Homo sapiens
221 TMPRSS11E  
Affinity Capture-MS Homo sapiens
222 LRBA 987
Proximity Label-MS Homo sapiens
223 ARL13B 200894
Proximity Label-MS Homo sapiens
224 OXR1  
Proximity Label-MS Homo sapiens
225 DNM1L 10059
Proximity Label-MS Homo sapiens
226 ARFGAP3 26286
Proximity Label-MS Homo sapiens
227 SLC4A7 9497
Proximity Label-MS Homo sapiens
228 AKAP10 11216
Proximity Label-MS Homo sapiens
229 SMCR8 140775
Proximity Label-MS Homo sapiens
230 OCRL 4952
Proximity Label-MS Homo sapiens
231 TBC1D22B  
Proximity Label-MS Homo sapiens
232 ARFGEF1 10565
Proximity Label-MS Homo sapiens
233 VAMP3 9341
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
234 PPP1R37 284352
Proximity Label-MS Homo sapiens
235 NR3C1 2908
Proximity Label-MS Homo sapiens
236 STIM1 6786
Proximity Label-MS Homo sapiens
237 MYO5A 4644
Proximity Label-MS Homo sapiens
238 ECE1 1889
Proximity Label-MS Homo sapiens
239 OCIAD1 54940
Proximity Label-MS Homo sapiens
240 TBC1D8  
Proximity Label-MS Homo sapiens
241 OSBPL11 114885
Proximity Label-MS Homo sapiens
242 ZFYVE28  
Co-localization Homo sapiens
243 SHISA2 387914
Proximity Label-MS Homo sapiens
244 SNX30 401548
Proximity Label-MS Homo sapiens
245 SLC9A7 84679
Proximity Label-MS Homo sapiens
246 RAF1 5894
Proximity Label-MS Homo sapiens
247 PTPN23 25930
Proximity Label-MS Homo sapiens
248 KTN1 3895
Proximity Label-MS Homo sapiens
249 CACNG1  
Affinity Capture-MS Homo sapiens
250 HLA-A 3105
Proximity Label-MS Homo sapiens
251 CHM 1121
Affinity Capture-MS Homo sapiens
252 ATP7A 538
Proximity Label-MS Homo sapiens
253 AKAP1 8165
Proximity Label-MS Homo sapiens
254 SLC12A2 6558
Proximity Label-MS Homo sapiens
255 UBE2J1 51465
Proximity Label-MS Homo sapiens
256 DMXL2  
Proximity Label-MS Homo sapiens
257 DEPDC1B 55789
Proximity Label-MS Homo sapiens
258 PVRL2 5819
Proximity Label-MS Homo sapiens
259 ALDH3A2 224
Proximity Label-MS Homo sapiens
260 SEC23IP 11196
Proximity Label-MS Homo sapiens
261 TOR1AIP2 163590
Proximity Label-MS Homo sapiens
262 PIN1 5300
Affinity Capture-Western Homo sapiens
263 TRAPPC8 22878
Proximity Label-MS Homo sapiens
264 LRP1 4035
Proximity Label-MS Homo sapiens
265 VAMP4 8674
Proximity Label-MS Homo sapiens
266 EFNB1 1947
Proximity Label-MS Homo sapiens
267 TBC1D2B 23102
Proximity Label-MS Homo sapiens
268 RABL6 55684
Proximity Label-MS Homo sapiens
269 IDH3A 3419
Two-hybrid Homo sapiens
270 PDZD8 118987
Proximity Label-MS Homo sapiens
271 RUFY2  
Proximity Label-MS Homo sapiens
272 INF2 64423
Proximity Label-MS Homo sapiens
273 FRS2 10818
Proximity Label-MS Homo sapiens
274 RAB7A 7879
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
275 LRP2 4036
Proximity Label-MS Homo sapiens
276 STT3B 201595
Proximity Label-MS Homo sapiens
277 SNX2 6643
Proximity Label-MS Homo sapiens
278 CAV1 857
Proximity Label-MS Homo sapiens
279 TPRA1  
Proximity Label-MS Homo sapiens
280 POR 5447
Proximity Label-MS Homo sapiens
281 ANKLE2 23141
Proximity Label-MS Homo sapiens
282 VTI1B 10490
Proximity Label-MS Homo sapiens
283 SNAP23 8773
Proximity Label-MS Homo sapiens
284 RABEP2 79874
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
285 CD2AP 23607
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
286 VPS13A 23230
Proximity Label-MS Homo sapiens
287 PTPN9 5780
Proximity Label-MS Homo sapiens
288 BASP1 10409
Proximity Label-MS Homo sapiens
289 LNPEP 4012
Proximity Label-MS Homo sapiens
290 SMAP2 64744
Proximity Label-MS Homo sapiens
291 SLC30A4 7782
Proximity Label-MS Homo sapiens
292 SNX6 58533
Proximity Label-MS Homo sapiens
293 SLC22A9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 RALGAPB 57148
Proximity Label-MS Homo sapiens
295 NISCH 11188
Proximity Label-MS Homo sapiens
296 WDR11 55717
Proximity Label-MS Homo sapiens
297 SLC39A10 57181
Proximity Label-MS Homo sapiens
298 CPD 1362
Proximity Label-MS Homo sapiens
299 STX7 8417
Proximity Label-MS Homo sapiens
300 SEMA4C 54910
Proximity Label-MS Homo sapiens
301 PGRMC2 10424
Proximity Label-MS Homo sapiens
302 EXD2  
Proximity Label-MS Homo sapiens
303 STX6 10228
Proximity Label-MS Homo sapiens
304 VPS53 55275
Proximity Label-MS Homo sapiens
305 CNN2 1265
Affinity Capture-MS Homo sapiens
306 FAF2 23197
Proximity Label-MS Homo sapiens
307 TMEM2 23670
Proximity Label-MS Homo sapiens
308 ATG2B 55102
Proximity Label-MS Homo sapiens
309 VIPAS39 63894
Proximity Label-MS Homo sapiens
310 LAMTOR1 55004
Proximity Label-MS Homo sapiens
311 LRRC59 55379
Proximity Label-MS Homo sapiens
312 MRC2 9902
Proximity Label-MS Homo sapiens
313 LMNB1 4001
Proximity Label-MS Homo sapiens
314 GCGR  
Affinity Capture-MS Homo sapiens
315 AGFG1 3267
Proximity Label-MS Homo sapiens
316 EMD 2010
Proximity Label-MS Homo sapiens
317 FAM71C  
Two-hybrid Homo sapiens
318 HTT 3064
Proximity Label-MS Homo sapiens
319 TPD52 7163
Proximity Label-MS Homo sapiens
320 GCC2 9648
Proximity Label-MS Homo sapiens
321 SPRY4 81848
Proximity Label-MS Homo sapiens
322 ATP9A 10079
Proximity Label-MS Homo sapiens
323 FAM135A  
Proximity Label-MS Homo sapiens
324 AP1B1 162
Proximity Label-MS Homo sapiens
325 SLC7A2 6542
Proximity Label-MS Homo sapiens
326 PEAK1 79834
Proximity Label-MS Homo sapiens
327 RAB11FIP5 26056
Proximity Label-MS Homo sapiens
328 SV2A 9900
Proximity Label-MS Homo sapiens
329 SLC33A1 9197
Proximity Label-MS Homo sapiens
330 SLC7A1 6541
Proximity Label-MS Homo sapiens
331 ACBD3 64746
Proximity Label-MS Homo sapiens
332 SNAP29 9342
Proximity Label-MS Homo sapiens
333 TEX2 55852
Proximity Label-MS Homo sapiens
334 BAG3 9531
Affinity Capture-Luminescence Homo sapiens
335 SNX1 6642
Proximity Label-MS Homo sapiens
336 CACHD1  
Proximity Label-MS Homo sapiens
337 ANKRD27  
Proximity Label-MS Homo sapiens
338 RALGAPA1 253959
Proximity Label-MS Homo sapiens
339 GOLGA3 2802
Proximity Label-MS Homo sapiens
340 RABGGTA 5875
Affinity Capture-MS Homo sapiens
341 CLINT1 9685
Proximity Label-MS Homo sapiens
342 VAPB 9217
Proximity Label-MS Homo sapiens
343 SLC39A6 25800
Proximity Label-MS Homo sapiens
344 ATP2B1 490
Proximity Label-MS Homo sapiens
345 SLC20A2 6575
Proximity Label-MS Homo sapiens
346 LAMP1 3916
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
347 SLC30A6 55676
Proximity Label-MS Homo sapiens
348 ARF1 375
Proximity Label-MS Homo sapiens
349 SLC7A5 8140
Proximity Label-MS Homo sapiens
350 RABGAP1 23637
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
351 EHBP1 23301
Proximity Label-MS Homo sapiens
352 GDI2 2665
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
353 PRKCI 5584
Affinity Capture-Western Homo sapiens
354 ACSL3 2181
Proximity Label-MS Homo sapiens
355 RAB2B 84932
Affinity Capture-MS Homo sapiens
356 LRIG1 26018
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
357 FNDC3A 22862
Proximity Label-MS Homo sapiens
358 STBD1 8987
Proximity Label-MS Homo sapiens
359 STX10 8677
Proximity Label-MS Homo sapiens
360 DNAJC13 23317
Proximity Label-MS Homo sapiens
361 SEC24B 10427
Proximity Label-MS Homo sapiens
362 KIAA1549  
Proximity Label-MS Homo sapiens
363 SPTAN1 6709
Proximity Label-MS Homo sapiens
364 USE1 55850
Proximity Label-MS Homo sapiens
365 ROCK1 6093
Proximity Label-MS Homo sapiens
366 UBXN4 23190
Proximity Label-MS Homo sapiens
367 ECSCR  
Affinity Capture-MS Homo sapiens
368 VPS52 6293
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
369 DOPEY2 9980
Proximity Label-MS Homo sapiens
370 SLC39A14 23516
Proximity Label-MS Homo sapiens
371 RAB1A 5861
Proximity Label-MS Homo sapiens
372 ESYT1 23344
Proximity Label-MS Homo sapiens
373 SLC38A1 81539
Proximity Label-MS Homo sapiens
374 SLC6A8 6535
Proximity Label-MS Homo sapiens
375 CDK5RAP3 80279
Proximity Label-MS Homo sapiens
376 RAB33B 83452
Affinity Capture-MS Homo sapiens
377 UBIAD1 29914
Proximity Label-MS Homo sapiens
378 VEZT 55591
Proximity Label-MS Homo sapiens
379 DSG2 1829
Proximity Label-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here