Gene description for KIF1B
Gene name
kinesin family member 1B
Gene symbol
KIF1B
Other names/aliases
CMT2 CMT2A CMT2A1 HMSNII KLP NBLST1
Species
Homo sapiens
Database cross references - KIF1B
ExoCarta
ExoCarta_23095
Entrez Gene
23095
HGNC
16636
MIM
605995
UniProt
O60333
KIF1B identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells
25944692
Thymus
23844026
Gene ontology annotations for KIF1B
Experiment description of studies that identified KIF1B in exosomes
1
Experiment ID
224
ISEV standards
✔
EM|AFM
EV Biophysical techniques
✔
Alix|TSG101
EV Cytosolic markers
✔
CD63|CD81
EV Membrane markers
✔
GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25944692
Organism
Homo sapiens
Experiment description
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors
Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name
Oncotarget
Publication year
2015
Sample
Neuroblastoma cells
Sample name
SH-SY5Y
Isolation/purification methods
Differential centrifugation Ultracentrifugation OptiPrep density gradient
Flotation density
1.10 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Western blotting
2
Experiment ID
217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23844026
Organism
Homo sapiens
Experiment description
Characterization of human thymic exosomes.
Authors
Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name
PLoS One
Publication year
2013
Sample
Thymus
Sample name
Normal-Thymus
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for KIF1B
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
DLG1
1739
Invitro
Homo sapiens
Invivo
Homo sapiens
Two-hybrid
Homo sapiens
2
BRCA1
672
Protein-peptide
Homo sapiens
3
GIPC1
10755
Invivo
Homo sapiens
Invitro
Homo sapiens
4
STARD13
Two-hybrid
Homo sapiens
5
DLG4
Invivo
Homo sapiens
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
6
EEF1A1
1915
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which KIF1B is involved
No pathways found