Gene ontology annotations for SFN |
|
Experiment description of studies that identified SFN in exosomes |
1 |
Experiment ID |
76 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|GAPDH|HSP90
|
EV Cytosolic markers |
✔
CD81|CD9|CD63|LAMP1|MHCI
|
EV Membrane markers |
✔
HSP90B1
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
20224111
|
Organism |
Homo sapiens |
Experiment description |
Proteomics analysis of bladder cancer exosomes. |
Authors |
Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A. |
Journal name |
MCP
|
Publication year |
2010 |
Sample |
Bladder cancer cells |
Sample name |
HT1376 |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient |
Flotation density |
1.10-1.19 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [MALDI TOF/TOF] Western blotting FACS |
|
|
2 |
Experiment ID |
21 |
ISEV standards |
✔
EM|IEM
|
EV Biophysical techniques |
✔
Alix|TSG101|HSP70
|
EV Cytosolic markers |
✔
CD63
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
|
PubMed ID |
19837982
|
Organism |
Homo sapiens |
Experiment description |
Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215. |
Authors |
Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson |
Journal name |
MCP
|
Publication year |
2009 |
Sample |
Colorectal cancer cells |
Sample name |
LIM1215 |
Isolation/purification methods |
Filtration Ultracentrifugation Sucrose density gradient |
Flotation density |
1.10-1.12 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [Orbitrap] Western blotting |
|
|
3 |
Experiment ID |
207 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|HSP70
|
EV Cytosolic markers |
✔
FLOT1
|
EV Membrane markers |
✔
VDAC
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23161513
|
Organism |
Homo sapiens |
Experiment description |
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. |
Authors |
Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year |
2012 |
Sample |
Colorectal cancer cells |
Sample name |
DKO-1 |
Isolation/purification methods |
Differential centrifugation Filtration |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
4 |
Experiment ID |
208 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|HSP70
|
EV Cytosolic markers |
✔
FLOT1
|
EV Membrane markers |
✔
VDAC
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23161513
|
Organism |
Homo sapiens |
Experiment description |
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. |
Authors |
Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year |
2012 |
Sample |
Colorectal cancer cells |
Sample name |
Dks-8 |
Isolation/purification methods |
Differential centrifugation Filtration |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
5 |
Experiment ID |
209 |
ISEV standards |
✘
|
EV Biophysical techniques |
✔
TSG101|HSP70
|
EV Cytosolic markers |
✔
FLOT1
|
EV Membrane markers |
✔
VDAC
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23161513
|
Organism |
Homo sapiens |
Experiment description |
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. |
Authors |
Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. |
Journal name |
Mol Cell Proteomics
|
Publication year |
2012 |
Sample |
Colorectal cancer cells |
Sample name |
DLD-1 |
Isolation/purification methods |
Differential centrifugation Filtration |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
6 |
Experiment ID |
32 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
HSC70
|
EV Cytosolic markers |
✔
LAMP2
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Western blotting
|
PubMed ID |
18452139
|
Organism |
Homo sapiens |
Experiment description |
Primary human keratinocytes externalize stratifin protein via exosomes. |
Authors |
RChavez-Muñoz C, Morse J, Kilani R, Ghahary A |
Journal name |
JCB
|
Publication year |
2008 |
Sample |
Keratinocytes |
Sample name |
Keratinocytes |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient Diafiltration |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting |
|
|
7 |
Experiment ID |
189 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
19530224
|
Organism |
Homo sapiens |
Experiment description |
Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. |
Authors |
Chavez-Muñoz C, Kilani RT, Ghahary A. |
Journal name |
J Cell Physiol
|
Publication year |
2009 |
Sample |
Keratinocytes |
Sample name |
Keratinocytes - Differentiated |
Isolation/purification methods |
Differential centrifugation Filtration Sucrose cushion Filtration |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
8 |
Experiment ID |
190 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
HSC70
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
19530224
|
Organism |
Homo sapiens |
Experiment description |
Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes. |
Authors |
Chavez-Muñoz C, Kilani RT, Ghahary A. |
Journal name |
J Cell Physiol
|
Publication year |
2009 |
Sample |
Keratinocytes |
Sample name |
Keratinocytes - Undifferentiated |
Isolation/purification methods |
Differential centrifugation Filtration Sucrose cushion Filtration |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
9 |
Experiment ID |
126 |
ISEV standards |
✘
|
EV Biophysical techniques |
✔
GAPDH
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry [LTQ-FT Ultra]
|
PubMed ID |
Unpublished / Not applicable
|
Organism |
Homo sapiens |
Experiment description |
Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy? |
Authors |
Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim |
Journal name |
Mesenchymal Stem Cell Therapy
|
Publication year |
2011 |
Sample |
Mesenchymal stem cells |
Sample name |
huES9.E1 |
Isolation/purification methods |
HPLC |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Antobody array Mass spectrometry |
|
|
10 |
Experiment ID |
224 |
ISEV standards |
✔
EM|AFM
|
EV Biophysical techniques |
✔
Alix|TSG101
|
EV Cytosolic markers |
✔
CD63|CD81
|
EV Membrane markers |
✔
GOLGA2
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25944692
|
Organism |
Homo sapiens |
Experiment description |
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes |
Authors |
Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S |
Journal name |
Oncotarget
|
Publication year |
2015 |
Sample |
Neuroblastoma cells |
Sample name |
SH-SY5Y |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation OptiPrep density gradient |
Flotation density |
1.10 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry Western blotting |
|
|
11 |
Experiment ID |
211 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|Alix
|
EV Cytosolic markers |
✔
EpCAM|TFRC
|
EV Membrane markers |
✔
cytochrome c|GOLGA2
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23333927
|
Organism |
Homo sapiens |
Experiment description |
Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors |
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year |
2013 |
Sample |
Ovarian cancer cells |
Sample name |
IGROV1 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
1.09-1.15 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
12 |
Experiment ID |
212 |
ISEV standards |
✔
CEM
|
EV Biophysical techniques |
✔
TSG101|Alix
|
EV Cytosolic markers |
✔
EpCAM|TFRC
|
EV Membrane markers |
✔
Cytochrome C|GOLGA2
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23333927
|
Organism |
Homo sapiens |
Experiment description |
Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors |
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year |
2013 |
Sample |
Ovarian cancer cells |
Sample name |
OVCAR-3 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
1.09-1.15 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
13 |
Experiment ID |
231 |
ISEV standards |
✘
|
EV Biophysical techniques |
✔
Alix
|
EV Cytosolic markers |
✔
CD63|CD9
|
EV Membrane markers |
✘
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25332113
|
Organism |
Homo sapiens |
Experiment description |
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets |
Authors |
Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G. |
Journal name |
Transfusion
|
Publication year |
2015 |
Sample |
Platelets |
Sample name |
PL-Exs - Rep 1 |
Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient |
Flotation density |
1.12-1.15 g/mL
|
Molecules identified in the study |
Protein Lipids |
Methods used in the study |
Western blotting Mass spectrometry |
|
|
14 |
Experiment ID |
232 |
ISEV standards |
✘
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25332113
|
Organism |
Homo sapiens |
Experiment description |
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets |
Authors |
Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G. |
Journal name |
Transfusion
|
Publication year |
2015 |
Sample |
Platelets |
Sample name |
PL-Exs - Rep 2 |
Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient |
Flotation density |
1.12-1.15 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
15 |
Experiment ID |
233 |
ISEV standards |
✘
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25332113
|
Organism |
Homo sapiens |
Experiment description |
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets |
Authors |
Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G. |
Journal name |
Transfusion
|
Publication year |
2015 |
Sample |
Platelets |
Sample name |
PL-Exs - Rep 3 |
Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient |
Flotation density |
1.12-1.15 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
16 |
Experiment ID |
275 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|Alix|RAB5A
|
EV Cytosolic markers |
✔
CD9|CD82|CD63|CD81
|
EV Membrane markers |
✔
AIF
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25844599
|
Organism |
Homo sapiens |
Experiment description |
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. |
Authors |
Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T. |
Journal name |
Oncotarget
|
Publication year |
2015 |
Sample |
Prostate cancer cells |
Sample name |
DU145 - Docetaxel sensitive |
Isolation/purification methods |
Filtration Ultracentrifugation Sucrose density gradient |
Flotation density |
1.12-1.19 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry/Flow cytometry/Western blotting |
|
|
17 |
Experiment ID |
274 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|Alix|RAB5A
|
EV Cytosolic markers |
✔
CD9|CD82|CD63|CD81
|
EV Membrane markers |
✔
AIF
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
25844599
|
Organism |
Homo sapiens |
Experiment description |
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel. |
Authors |
Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T. |
Journal name |
Oncotarget
|
Publication year |
2015 |
Sample |
Prostate cancer cells |
Sample name |
DU145 - Docetaxel resistant |
Isolation/purification methods |
Filtration Ultracentrifugation Sucrose density gradient |
Flotation density |
1.13-1.18 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry Flow cytometry Western blotting |
|
|
18 |
Experiment ID |
191 |
ISEV standards |
✘
|
EV Biophysical techniques |
✔
Alix
|
EV Cytosolic markers |
✔
CD81|CD9
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
20124223
|
Organism |
Homo sapiens |
Experiment description |
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. |
Authors |
Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK. |
Journal name |
Mol Cell Proteomics
|
Publication year |
2010 |
Sample |
Squamous carcinoma cells |
Sample name |
Squamous carcinoma cell (A431) |
Isolation/purification methods |
Differential centrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
19 |
Experiment ID |
217 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101
|
EV Cytosolic markers |
✔
CD81|CD9|CD63
|
EV Membrane markers |
✘
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23844026
|
Organism |
Homo sapiens |
Experiment description |
Characterization of human thymic exosomes. |
Authors |
Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O. |
Journal name |
PLoS One
|
Publication year |
2013 |
Sample |
Thymus |
Sample name |
Normal-Thymus |
Isolation/purification methods |
Differential centrifugation Filtration Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
20 |
Experiment ID |
13 |
ISEV standards |
✔
IEM
|
EV Biophysical techniques |
✔
Alix|RAB4|RAB5B|RAB11|TSG101
|
EV Cytosolic markers |
✔
CD9|AQP2|AQP1
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
15326289
|
Organism |
Homo sapiens |
Experiment description |
Identification and proteomic profiling of exosomes in human urine. |
Authors |
Pisitkun T, Shen RF, Knepper MA |
Journal name |
PNAS
|
Publication year |
2004 |
Sample |
Urine |
Sample name |
Urine - Normal |
Isolation/purification methods |
Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [LCQ DECA XP] Western blotting |
|
|
21 |
Experiment ID |
63 |
ISEV standards |
✘
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✔
AQP2
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
19056867
|
Organism |
Homo sapiens |
Experiment description |
Large-scale proteomics and phosphoproteomics of urinary exosomes. |
Authors |
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA |
Journal name |
JASN
|
Publication year |
2009 |
Sample |
Urine |
Sample name |
Urine - Normal |
Isolation/purification methods |
Differential centrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [LTQ] Western blotting |
|
|
22 |
Experiment ID |
193 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✔
CD63|CD9
|
EV Membrane markers |
✔
PHB
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
21595033
|
Organism |
Homo sapiens |
Experiment description |
Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors |
Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year |
2011 |
Sample |
Urine |
Sample name |
Urine - Normal |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
23 |
Experiment ID |
194 |
ISEV standards |
✘
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
21595033
|
Organism |
Homo sapiens |
Experiment description |
Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors |
Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year |
2011 |
Sample |
Urine |
Sample name |
Urine - Patients of basement membrane nephropathy |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
24 |
Experiment ID |
195 |
ISEV standards |
✘
|
EV Biophysical techniques |
✘
|
EV Cytosolic markers |
✘
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
21595033
|
Organism |
Homo sapiens |
Experiment description |
Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. |
Authors |
Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC. |
Journal name |
Proteomics
|
Publication year |
2011 |
Sample |
Urine |
Sample name |
Urine - Patients of early IgA nephropathy |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
25 |
Experiment ID |
196 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
Alix|TSG101|HSP70
|
EV Cytosolic markers |
✔
CD9
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
22418980
|
Organism |
Homo sapiens |
Experiment description |
A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. |
Authors |
Raj DA, Fiume I, Capasso G, Pocsfalvi G. |
Journal name |
Kidney Int
|
Publication year |
2012 |
Sample |
Urine |
Sample name |
Urine - Normal high density |
Isolation/purification methods |
Differential centrifugation Sucrose cushion |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
26 |
Experiment ID |
197 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
Alix|TSG101|HSP70
|
EV Cytosolic markers |
✔
CD9
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
22418980
|
Organism |
Homo sapiens |
Experiment description |
A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. |
Authors |
Raj DA, Fiume I, Capasso G, Pocsfalvi G. |
Journal name |
Kidney Int
|
Publication year |
2012 |
Sample |
Urine |
Sample name |
Urine - Normal low density |
Isolation/purification methods |
Differential centrifugation Sucrose cushion |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
Protein-protein interactions for SFN |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
1 |
ARHGAP21 |
57584 |
Affinity Capture-MS |
 |
Homo sapiens |
|
2 |
HDAC4 |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
3 |
HDAC7A |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
4 |
PKP2 |
5318 |
Affinity Capture-MS |
 |
Homo sapiens |
|
5 |
PPP1R3D |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
6 |
RACGAP1 |
29127 |
Affinity Capture-MS |
 |
Homo sapiens |
|
7 |
PARD3 |
56288 |
Affinity Capture-MS |
 |
Homo sapiens |
|
8 |
APC |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
9 |
PLEKHF2 |
79666 |
Two-hybrid |
 |
Homo sapiens |
|
10 |
SASH1 |
23328 |
Affinity Capture-MS |
 |
Homo sapiens |
|
11 |
CSNK2A1 |
1457 |
Affinity Capture-MS |
 |
Homo sapiens |
|
12 |
ANKS1A |
23294 |
Affinity Capture-MS |
 |
Homo sapiens |
|
13 |
GRB7 |
2886 |
Affinity Capture-MS |
 |
Homo sapiens |
|
14 |
MARK2 |
2011 |
Affinity Capture-MS |
 |
Homo sapiens |
|
15 |
SHCBP1 |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
16 |
PAK4 |
10298 |
Affinity Capture-MS |
 |
Homo sapiens |
|
17 |
KIF23 |
9493 |
Affinity Capture-MS |
 |
Homo sapiens |
|
18 |
KLC2 |
64837 |
Affinity Capture-MS |
 |
Homo sapiens |
|
19 |
ZNF638 |
27332 |
Affinity Capture-MS |
 |
Homo sapiens |
|
20 |
KIF5B |
3799 |
Affinity Capture-MS |
 |
Homo sapiens |
|
21 |
PLK4 |
|
Two-hybrid |
 |
Homo sapiens |
Affinity Capture-Western |
 |
Homo sapiens |
|
22 |
RHPN2 |
85415 |
Affinity Capture-MS |
 |
Homo sapiens |
|
23 |
SRRM2 |
23524 |
Affinity Capture-MS |
 |
Homo sapiens |
|
24 |
YWHAG |
7532 |
Affinity Capture-MS |
 |
Homo sapiens |
Affinity Capture-MS |
 |
Homo sapiens |
|
25 |
SIPA1L1 |
26037 |
Affinity Capture-MS |
 |
Homo sapiens |
|
26 |
PPFIBP2 |
8495 |
Affinity Capture-MS |
 |
Homo sapiens |
|
27 |
TNS4 |
84951 |
Affinity Capture-MS |
 |
Homo sapiens |
|
28 |
USP8 |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
29 |
ARHGEF17 |
9828 |
Affinity Capture-MS |
 |
Homo sapiens |
|
30 |
PTPN3 |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
31 |
MAP3K2 |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
32 |
ARGBP2 |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
33 |
ISCU |
23479 |
Affinity Capture-MS |
 |
Homo sapiens |
|
34 |
SH3BP4 |
23677 |
Affinity Capture-MS |
 |
Homo sapiens |
|
35 |
KLHDC2 |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
36 |
KLC1 |
3831 |
Affinity Capture-MS |
 |
Homo sapiens |
|
37 |
TBL3 |
|
Two-hybrid |
 |
Homo sapiens |
|
38 |
APLP2 |
334 |
Affinity Capture-MS |
 |
Homo sapiens |
|
39 |
ABLIM1 |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
40 |
NEDD4L |
23327 |
Affinity Capture-MS |
 |
Homo sapiens |
|
41 |
DCAF7 |
10238 |
Affinity Capture-MS |
 |
Homo sapiens |
|
42 |
ARHGAP11A |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
43 |
CHEK1 |
|
Affinity Capture-Western |
 |
Homo sapiens |
|
44 |
PI4KB |
5298 |
Affinity Capture-MS |
 |
Homo sapiens |
|
45 |
TRIM32 |
22954 |
Affinity Capture-MS |
 |
Homo sapiens |
|
46 |
RALGPS2 |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
47 |
BRAF |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
48 |
ITCH |
83737 |
Affinity Capture-MS |
 |
Homo sapiens |
|
49 |
ST5 |
6764 |
Affinity Capture-MS |
 |
Homo sapiens |
|
50 |
FLJ10204 |
|
Two-hybrid |
 |
Homo sapiens |
|
51 |
CHST1 |
8534 |
Two-hybrid |
 |
Homo sapiens |
|
52 |
GAN |
8139 |
Affinity Capture-MS |
 |
Homo sapiens |
|
53 |
PTOV1 |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
54 |
SYNJ2 |
8871 |
Affinity Capture-MS |
 |
Homo sapiens |
|
55 |
MYCBP2 |
23077 |
Affinity Capture-MS |
 |
Homo sapiens |
|
56 |
KRT18 |
3875 |
Affinity Capture-MS |
 |
Homo sapiens |
|
57 |
SHROOM3 |
57619 |
Affinity Capture-MS |
 |
Homo sapiens |
|
58 |
LMO7 |
4008 |
Affinity Capture-MS |
 |
Homo sapiens |
|
59 |
DTX2 |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
60 |
LAD1 |
3898 |
Affinity Capture-MS |
 |
Homo sapiens |
|
61 |
NR3C1 |
2908 |
Two-hybrid |
 |
Homo sapiens |
Affinity Capture-MS |
 |
Homo sapiens |
|
62 |
JUB |
|
Affinity Capture-MS |
 |
Homo sapiens |
Affinity Capture-Western |
 |
Homo sapiens |
|
63 |
ARHGEF16 |
27237 |
Affinity Capture-MS |
 |
Homo sapiens |
|
64 |
PIK3C2B |
5287 |
Affinity Capture-MS |
 |
Homo sapiens |
|
65 |
WEE1 |
7465 |
Affinity Capture-MS |
 |
Homo sapiens |
|
66 |
C9orf61 |
|
Two-hybrid |
 |
Homo sapiens |
|
67 |
M-RIP |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
68 |
RND3 |
390 |
Affinity Capture-MS |
 |
Homo sapiens |
|
69 |
TJP2 |
9414 |
Affinity Capture-MS |
 |
Homo sapiens |
|
70 |
ARHGEF5 |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
71 |
SAV1 |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
72 |
PPFIBP1 |
8496 |
Affinity Capture-MS |
 |
Homo sapiens |
|
73 |
CGN |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
74 |
RAF1 |
5894 |
Affinity Capture-MS |
 |
Homo sapiens |
|
75 |
SRSF10 |
10772 |
Affinity Capture-MS |
 |
Homo sapiens |
|
76 |
ZAK |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
77 |
MIG-6 |
|
Affinity Capture-MS |
 |
Homo sapiens |
Affinity Capture-Western |
 |
Homo sapiens |
|
78 |
ARAF |
369 |
Affinity Capture-MS |
 |
Homo sapiens |
|
79 |
DYRK1A |
|
Affinity Capture-MS |
 |
Homo sapiens |
|
80 |
| | |