Gene description for NFIA
Gene name nuclear factor I/A
Gene symbol NFIA
Other names/aliases CTF
NF-I/A
NF1-A
NFI-A
NFI-L
Species Homo sapiens
 Database cross references - NFIA
ExoCarta ExoCarta_4774
Entrez Gene 4774
HGNC 7784
MIM 600727
UniProt Q12857  
 NFIA identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for NFIA
Molecular Function
    transcription factor binding GO:0008134 IPI
    RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978 IDA
    RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription GO:0001077 IDA
    sequence-specific DNA binding transcription factor activity GO:0003700 NAS
Biological Process
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IBA
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA
    transcription, DNA-templated GO:0006351 IEA
    regulation of transcription, DNA-templated GO:0006355 NAS
    viral genome replication GO:0019079 NAS
    response to organic cyclic compound GO:0014070 IEA
    DNA replication GO:0006260 IEA
Subcellular Localization
    cell junction GO:0030054 IDA
    nucleoplasm GO:0005654 IDA
    nucleus GO:0005634 NAS
 Experiment description of studies that identified NFIA in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for NFIA
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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