Gene description for NR3C1
Gene name	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Gene symbol	NR3C1
Other names/aliases	GCCR GCR GCRST GR GRL
Species	Homo sapiens
Database cross references - NR3C1
ExoCarta	ExoCarta_2908
Entrez Gene	2908
HGNC	7978
MIM	138040
UniProt	P04150
NR3C1 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for NR3C1

Molecular Function     glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity GO:0038051 IDA     RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978 IDA     steroid binding GO:0005496 IDA     steroid hormone binding GO:1990239 IDA     sequence-specific DNA binding transcription factor activity GO:0003700 IDA     zinc ion binding GO:0008270 IEA     protein binding GO:0005515 IPI     glucocorticoid receptor activity GO:0004883 TAS     protein dimerization activity GO:0046983 IEA     RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription GO:0001077 IDA Biological Process     adrenal gland development GO:0030325 IEA     regulation of gluconeogenesis GO:0006111 IEA     maternal behavior GO:0042711 IEA     signal transduction GO:0007165 TAS     positive regulation of neuron apoptotic process GO:0043525 IEA     regulation of glucocorticoid biosynthetic process GO:0031946 IEA     regulation of transcription, DNA-templated GO:0006355 IDA     glucocorticoid metabolic process GO:0008211 IEA     glucocorticoid receptor signaling pathway GO:0042921 IEA     mammary gland duct morphogenesis GO:0060603 IEA     positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA     glucocorticoid mediated signaling pathway GO:0043402 IEA     transcription from RNA polymerase II promoter GO:0006366 TAS     cellular response to steroid hormone stimulus GO:0071383 IDA     transcription initiation from RNA polymerase II promoter GO:0006367 TAS     negative regulation of glucocorticoid mediated signaling pathway GO:1900170 IEA     gene expression GO:0010467 TAS     transcription, DNA-templated GO:0006351 TAS     chromatin modification GO:0016568 IEA Subcellular Localization     cytosol GO:0005829 IEA     nucleoplasm GO:0005654 TAS     nucleus GO:0005634 IDA     membrane GO:0016020 IEA     cytoplasm GO:0005737 IDA     mitochondrial matrix GO:0005759 TAS