Gene description for IL1RAPL1
Gene name	interleukin 1 receptor accessory protein-like 1
Gene symbol	IL1RAPL1
Other names/aliases	IL1R8 IL1RAPL MRX10 MRX21 MRX34 OPHN4 TIGIRR-2
Species	Homo sapiens
Database cross references - IL1RAPL1
ExoCarta	ExoCarta_11141
Vesiclepedia	VP_11141
Entrez Gene	11141
HGNC	5996
MIM	300206
UniProt	Q9NZN1
IL1RAPL1 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for IL1RAPL1

Molecular Function     NAD+ nucleosidase activity GO:0003953 IEA     signaling receptor binding GO:0005102 ISS     protein binding GO:0005515 IPI     interleukin-1 binding GO:0019966 IDA     NAD+ nucleotidase, cyclic ADP-ribose generating GO:0061809 IEA Biological Process     cell surface receptor signaling pathway GO:0007166 IBA     regulation of neuron projection development GO:0010975 ISS     neuron differentiation GO:0030182 ISS     negative regulation of exocytosis GO:0045920 IBA     negative regulation of exocytosis GO:0045920 IDA     positive regulation of synapse assembly GO:0051965 ISS     positive regulation of dendritic spine morphogenesis GO:0061003 ISS     presynaptic membrane assembly GO:0097105 ISS     regulation of postsynapse organization GO:0099175 IDA     regulation of postsynapse organization GO:0099175 IMP     trans-synaptic signaling by trans-synaptic complex GO:0099545 IDA     trans-synaptic signaling by trans-synaptic complex GO:0099545 IMP     synaptic membrane adhesion GO:0099560 ISS     regulation of presynapse assembly GO:1905606 IDA     regulation of presynapse assembly GO:1905606 IMP Subcellular Localization     cytoplasm GO:0005737 IEA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     cell surface GO:0009986 IBA     cell surface GO:0009986 ISS     axon GO:0030424 IEA     dendrite GO:0030425 ISS     postsynaptic membrane GO:0045211 NAS     glutamatergic synapse GO:0098978 IDA     glutamatergic synapse GO:0098978 IMP