Gene description for POGZ
Gene name pogo transposable element with ZNF domain
Gene symbol POGZ
Other names/aliases ZNF280E
ZNF635
ZNF635m
Species Homo sapiens
 Database cross references - POGZ
ExoCarta ExoCarta_23126
Entrez Gene 23126
HGNC 18801
MIM 614787
UniProt Q7Z3K3  
 POGZ identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for POGZ
Molecular Function
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
    DNA binding GO:0003677 IEA
Biological Process
    mitotic sister chromatid cohesion GO:0007064 IMP
    cell division GO:0051301 IEA
    kinetochore assembly GO:0051382 IMP
Subcellular Localization
    nuclear chromatin GO:0000790 IDA
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified POGZ in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for POGZ
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SP1  
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which POGZ is involved
No pathways found





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