Gene description for FUK
Gene name fucokinase
Gene symbol FUK
Other names/aliases 1110046B12Rik
Species Homo sapiens
 Database cross references - FUK
ExoCarta ExoCarta_197258
Vesiclepedia VP_197258
Entrez Gene 197258
HGNC 29500
MIM 608675
UniProt Q8N0W3  
 FUK identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 34887515    
Thymus 23844026    
 Gene ontology annotations for FUK
Molecular Function
    fucokinase activity GO:0050201 NAS
    ATP binding GO:0005524 IEA
Biological Process
    phosphorylation GO:0016310 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified FUK in exosomes
1
Experiment ID 1203
MISEV standards
EM
EV Biophysical techniques
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ.
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
2
Experiment ID 217
MISEV standards
EM
EV Biophysical techniques
TSG101|CD81|CD9|CD63
EV Enriched markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FUK
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FUK is involved
No pathways found





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