Gene description for CD4
Gene name	CD4 molecule
Gene symbol	CD4
Other names/aliases	CD4mut
Species	Homo sapiens
Database cross references - CD4
ExoCarta	ExoCarta_920
Vesiclepedia	VP_920
Entrez Gene	920
HGNC	1678
MIM	186940
UniProt	P01730
CD4 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for CD4

Molecular Function     protein homodimerization activity GO:0042803 IDA     enzyme binding GO:0019899 IPI     transmembrane signaling receptor activity GO:0004888 TAS     protein binding GO:0005515 IPI     protein kinase binding GO:0019901 IPI     coreceptor activity GO:0015026 NAS     extracellular matrix structural constituent GO:0005201 NAS     zinc ion binding GO:0008270 IDA     receptor activity GO:0004872 TAS     glycoprotein binding GO:0001948 IPI     MHC class II protein binding GO:0042289 NAS Biological Process     positive regulation of protein kinase activity GO:0045860 IDA     entry into host cell GO:0030260 TAS     induction by virus of host cell-cell fusion GO:0006948 IDA     positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 IEA     immune response GO:0006955 NAS     regulation of T cell activation GO:0050863 IDA     viral process GO:0016032 TAS     signal transduction GO:0007165 TAS     transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 NAS     enzyme linked receptor protein signaling pathway GO:0007167 TAS     protein palmitoleylation GO:0045234 IDA     T cell receptor signaling pathway GO:0050852 TAS     cytokine production GO:0001816 IEA     T cell differentiation GO:0030217 IDA     positive regulation of interleukin-2 biosynthetic process GO:0045086 NAS     regulation of defense response to virus by virus GO:0050690 TAS     cell surface receptor signaling pathway GO:0007166 TAS     defense response to Gram-negative bacterium GO:0050829 IEA     T cell selection GO:0045058 IDA     positive regulation of calcium-mediated signaling GO:0050850 IEA     T cell costimulation GO:0031295 TAS     maintenance of protein location in cell GO:0032507 IDA     innate immune response GO:0045087 TAS Subcellular Localization     integral component of membrane GO:0016021 IEA     external side of plasma membrane GO:0009897 IDA     T cell receptor complex GO:0042101 NAS     membrane raft GO:0045121 IEA     plasma membrane GO:0005886 TAS     early endosome GO:0005769 TAS     endoplasmic reticulum lumen GO:0005788 IEA     endoplasmic reticulum membrane GO:0005789 TAS