Gene description for RPL7
Gene name ribosomal protein L7
Gene symbol RPL7
Other names/aliases L7
humL7-1
Species Homo sapiens
 Database cross references - RPL7
ExoCarta ExoCarta_6129
Vesiclepedia VP_6129
Entrez Gene 6129
HGNC 10363
MIM 604166
UniProt P18124  
 RPL7 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for RPL7
Molecular Function
    DNA binding GO:0003677 IDA
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IBA
    mRNA binding GO:0003729 IDA
    structural constituent of ribosome GO:0003735 IBA
    structural constituent of ribosome GO:0003735 IDA
    structural constituent of ribosome GO:0003735 IMP
    structural constituent of ribosome GO:0003735 NAS
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
Biological Process
    maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000463 IBA
    cytoplasmic translation GO:0002181 IC
    cytoplasmic translation GO:0002181 NAS
    rRNA processing GO:0006364 IMP
    translation GO:0006412 NAS
    ribosomal large subunit biogenesis GO:0042273 IMP
Subcellular Localization
    nucleus GO:0005634 HDA
    nucleolus GO:0005730 HDA
    cytoplasm GO:0005737 HDA
    cytoplasm GO:0005737 NAS
    cytosol GO:0005829 TAS
    focal adhesion GO:0005925 HDA
    postsynaptic density GO:0014069 EXP
    postsynaptic density GO:0014069 IDA
    membrane GO:0016020 HDA
    cytosolic large ribosomal subunit GO:0022625 HDA
    cytosolic large ribosomal subunit GO:0022625 IBA
    cytosolic large ribosomal subunit GO:0022625 IDA
    cytosolic large ribosomal subunit GO:0022625 IPI
    cytosolic ribosome GO:0022626 IDA
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified RPL7 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 494
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 498
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 282
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
14
Experiment ID 283
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
15
Experiment ID 285
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
16
Experiment ID 286
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
17
Experiment ID 1203
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
18
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 254
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 255
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 256
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 257
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 258
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 259
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 260
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
37
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 224
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
40
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
42
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
43
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
45
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
46
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
47
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
48
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
49
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
50
Experiment ID 275
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
51
Experiment ID 834
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
52
Experiment ID 835
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
53
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
54
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
55
Experiment ID 217
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPL7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZNF771  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 UBL4A 8266
Affinity Capture-MS Homo sapiens
3 ZBTB11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 ZNF346  
Affinity Capture-MS Homo sapiens
5 EIF3C 8663
Co-fractionation Homo sapiens
6 RIN3  
Affinity Capture-MS Homo sapiens
7 TRIM26 7726
Affinity Capture-MS Homo sapiens
8 EBNA-LP  
Affinity Capture-MS
9 KIF20A 10112
Affinity Capture-MS Homo sapiens
10 MRPL27 51264
Affinity Capture-MS Homo sapiens
11 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
12 NHP2L1 4809
Co-fractionation Homo sapiens
13 EFNA3  
Affinity Capture-MS Homo sapiens
14 DTX3  
Affinity Capture-MS Homo sapiens
15 KIF23 9493
Affinity Capture-MS Homo sapiens
16 PPP6C 5537
Affinity Capture-MS Homo sapiens
17 METAP2 10988
Affinity Capture-MS Homo sapiens
18 FBL 2091
Co-fractionation Homo sapiens
19 Nudt21 68219
Two-hybrid Mus musculus
20 RPS9 6203
Co-fractionation Homo sapiens
21 POLR2C 5432
Proximity Label-MS Homo sapiens
22 ARIH2 10425
Affinity Capture-MS Homo sapiens
23 RPS11 6205
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
24 RPL19 6143
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
25 KIF14 9928
Affinity Capture-MS Homo sapiens
26 EMC9  
Affinity Capture-MS Homo sapiens
27 BAG5 9529
Affinity Capture-MS Homo sapiens
28 MTCH2 23788
Affinity Capture-MS Homo sapiens
29 TMX1 81542
Co-fractionation Homo sapiens
30 MAPRE1 22919
Affinity Capture-MS Homo sapiens
31 TUFM 7284
Co-fractionation Homo sapiens
32 RPL18A 6142
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
33 PABPC1 26986
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
34 Srp72  
Affinity Capture-MS Mus musculus
35 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 TRIM21 6737
Affinity Capture-MS Homo sapiens
37 OGT 8473
Reconstituted Complex Homo sapiens
38 RPL31 6160
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
39 NOC4L 79050
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 NOS2  
Affinity Capture-MS Homo sapiens
41 YWHAQ 10971
Reconstituted Complex Homo sapiens
42 HECTD1 25831
Affinity Capture-MS Homo sapiens
43 CUL2 8453
Affinity Capture-MS Homo sapiens
44 MAGEB2 4113
Affinity Capture-MS Homo sapiens
45 SEC61B 10952
Affinity Capture-MS Homo sapiens
46 SLC25A5 292
Co-fractionation Homo sapiens
47 CNBP 7555
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 ANLN 54443
Affinity Capture-MS Homo sapiens
49 HIST1H2AD 3013
Co-fractionation Homo sapiens
50 TMPO 7112
Affinity Capture-MS Homo sapiens
51 RBM39 9584
Affinity Capture-MS Homo sapiens
52 UBE3A 7337
Affinity Capture-MS Homo sapiens
53 SIRT7  
Affinity Capture-MS Homo sapiens
54 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 EBNA1BP2 10969
Co-fractionation Homo sapiens
56 FN1 2335
Affinity Capture-MS Homo sapiens
57 PCBP1 5093
Affinity Capture-MS Homo sapiens
58 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
59 MAGEB10  
Affinity Capture-MS Homo sapiens
60 RPL35A 6165
Co-fractionation Homo sapiens
61 HSPA1A 3303
Cross-Linking-MS (XL-MS) Homo sapiens
62 Rpl35 66489
Affinity Capture-MS Mus musculus
63 ZFP62  
Affinity Capture-MS Homo sapiens
64 GNL3 26354
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
65 RPS16 6217
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
66 YBX1 4904
Affinity Capture-MS Homo sapiens
67 RRS1 23212
Co-fractionation Homo sapiens
68 ZEB1  
Affinity Capture-MS Homo sapiens
69 SRSF12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 EMC4 51234
Affinity Capture-MS Homo sapiens
71 PIK3R4 30849
Affinity Capture-MS Homo sapiens
72 CAPZB 832
Affinity Capture-MS Homo sapiens
73 G3BP2 9908
Affinity Capture-MS Homo sapiens
74 H2AFB3  
Affinity Capture-MS Homo sapiens
75 KRI1  
Affinity Capture-MS Homo sapiens
76 KRR1 11103
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 NEIL1  
Affinity Capture-MS Homo sapiens
78 DARS-AS1  
Protein-RNA Homo sapiens
79 RPS24 6229
Co-fractionation Homo sapiens
80 NCL 4691
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
81 HNF1B  
Affinity Capture-MS Homo sapiens
82 MATN2 4147
Affinity Capture-MS Homo sapiens
83 EIF2S3 1968
Affinity Capture-MS Homo sapiens
84 TARDBP 23435
Affinity Capture-MS Homo sapiens
85 RPA2 6118
Affinity Capture-MS Homo sapiens
86 VPRBP 9730
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 NOP56 10528
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
88 HSP90AB1 3326
Affinity Capture-MS Homo sapiens
89 CAND1 55832
Affinity Capture-MS Homo sapiens
90 RPS3 6188
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
91 RPS18 6222
Co-fractionation Homo sapiens
92 PGK1 5230
Cross-Linking-MS (XL-MS) Homo sapiens
93 B3GNT2 10678
Affinity Capture-MS Homo sapiens
94 HSP90AA1 3320
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
95 DDX24 57062
Co-fractionation Homo sapiens
96 RRP12 23223
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 PRC1 9055
Affinity Capture-MS Homo sapiens
98 NPM1 4869
Affinity Capture-MS Homo sapiens
99 RECQL4  
Affinity Capture-MS Homo sapiens
100 OBSL1 23363
Affinity Capture-MS Homo sapiens
101 NR4A1  
Two-hybrid Homo sapiens
102 VCAM1 7412
Affinity Capture-MS Homo sapiens
103 MRPS7 51081
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 Eif3a 13669
Affinity Capture-MS Mus musculus
105 RBM42  
Affinity Capture-MS Homo sapiens
106 ZNF184  
Affinity Capture-MS Homo sapiens
107 RPL10L 140801
Co-fractionation Homo sapiens
108 PES1 23481
Co-fractionation Homo sapiens
109 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
110 DDX21 9188
Co-fractionation Homo sapiens
111 RPL4 6124
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
112 DRG1 4733
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 MSX2  
Affinity Capture-MS Homo sapiens
114 ACIN1 22985
Co-fractionation Homo sapiens
115 VRK1 7443
Affinity Capture-MS Homo sapiens
116 NKRF 55922
Affinity Capture-MS Homo sapiens
117 MAGOH 4116
Affinity Capture-MS Homo sapiens
118 RPLP0 6175
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
119 RPLP0P6 220717
Co-fractionation Homo sapiens
120 CYLD  
Affinity Capture-MS Homo sapiens
121 RPL29 6159
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
122 KDF1  
Affinity Capture-MS Homo sapiens
123 MAP2K1 5604
Affinity Capture-MS Homo sapiens
124 HNRNPD 3184
Cross-Linking-MS (XL-MS) Homo sapiens
125 RPL32 6161
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
126 ZNF770 54989
Affinity Capture-MS Homo sapiens
127 RPS2 6187
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
128 POP1 10940
Affinity Capture-MS Homo sapiens
129 EIF6 3692
Co-fractionation Homo sapiens
130 RC3H2  
Affinity Capture-MS Homo sapiens
131 ZBTB24  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 TUBB4B 10383
Co-fractionation Homo sapiens
133 EGFR 1956
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
134 FAM90A1  
Affinity Capture-MS Homo sapiens
135 HSP90AA5P 730211
Co-fractionation Homo sapiens
136 LARS 51520
Affinity Capture-MS Homo sapiens
137 RPS27 6232
Co-fractionation Homo sapiens
138 CDK2 1017
Affinity Capture-MS Homo sapiens
139 CEP250 11190
Affinity Capture-MS Homo sapiens
140 MAP2K3 5606
Affinity Capture-MS Homo sapiens
141 NEFM 4741
Cross-Linking-MS (XL-MS) Homo sapiens
142 BAG1 573
Affinity Capture-MS Homo sapiens
143 GZF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 CUL7 9820
Affinity Capture-MS Homo sapiens
145 DDRGK1 65992
Affinity Capture-MS Homo sapiens
146 BMI1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 CCDC140  
Affinity Capture-MS Homo sapiens
148 RPL26 6154
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 EEF1A1 1915
Co-fractionation Homo sapiens
150 RPL13 6137
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
151 SURF6  
Affinity Capture-MS Homo sapiens
152 PSMB10 5699
Affinity Capture-MS Homo sapiens
153 SPOP  
Affinity Capture-MS Homo sapiens
154 ILF3 3609
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
155 TP53 7157
Affinity Capture-MS Homo sapiens
156 FOLR1 2348
Affinity Capture-MS Homo sapiens
157 SRP19 6728
Affinity Capture-MS Homo sapiens
158 RPS4X 6191
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
159 UTP23  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
161 GNL1 2794
Co-fractionation Homo sapiens
162 RPS5 6193
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
163 NIFK 84365
Co-fractionation Homo sapiens
164 RPS26 6231
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
165 RNF38  
Affinity Capture-MS Homo sapiens
166 CHMP4C 92421
Affinity Capture-MS Homo sapiens
167 RPL7A 6130
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
168 ARF1 375
Proximity Label-MS Homo sapiens
169 RPS29 6235
Co-fractionation Homo sapiens
170 PHC2  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 MYC  
Affinity Capture-MS Homo sapiens
172 PRMT1 3276
Affinity Capture-MS Homo sapiens
173 RALY 22913
Affinity Capture-MS Homo sapiens
174 ZNF668  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
175 RPSA 3921
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
176 RPL26L1 51121
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 NOP58 51602
Co-fractionation Homo sapiens
178 DNAJC8 22826
Affinity Capture-MS Homo sapiens
179 CD4 920
Affinity Capture-MS Homo sapiens
180 RPS19 6223
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
181 SSB 6741
Affinity Capture-MS Homo sapiens
182 HNRNPR 10236
Co-fractionation Homo sapiens
183 ATG13 9776
Affinity Capture-MS Homo sapiens
184 DIMT1 27292
Affinity Capture-MS Homo sapiens
185 RPL10A 4736
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
186 MCM2 4171
Affinity Capture-MS Homo sapiens
187 CDK12 51755
Cross-Linking-MS (XL-MS) Homo sapiens
188 LOC101929876 101929876
Co-fractionation Homo sapiens
189 TFCP2 7024
Affinity Capture-MS Homo sapiens
190 PABPC4 8761
Co-fractionation Homo sapiens
191 RBM8A 9939
Affinity Capture-MS Homo sapiens
192 RBM19 9904
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 HSPA8 3312
Co-fractionation Homo sapiens
194 BRIX1 55299
Co-fractionation Homo sapiens
195 RPL27 6155
Co-fractionation Homo sapiens
196 FOXA1  
Affinity Capture-MS Homo sapiens
197 RPL9 6133
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
198 CUL4B 8450
Affinity Capture-MS Homo sapiens
199 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
200 RPS10 6204
Co-fractionation Homo sapiens
201 BLM 641
Synthetic Growth Defect Homo sapiens
202 TUBGCP4 27229
Affinity Capture-MS Homo sapiens
203 NOP2 4839
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
204 RPL5 6125
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
205 CHMP4B 128866
Affinity Capture-MS Homo sapiens
206 CNOT1 23019
Affinity Capture-MS Homo sapiens
207 BTF3 689
Affinity Capture-MS Homo sapiens
208 RAN 5901
Reconstituted Complex Homo sapiens
209 NTRK1 4914
Affinity Capture-MS Homo sapiens
210 ARNT 405
Affinity Capture-MS Homo sapiens
211 RPL36 25873
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
212 RPA4  
Proximity Label-MS Homo sapiens
213 RPLP1 6176
Co-fractionation Homo sapiens
214 ENY2 56943
Affinity Capture-MS Homo sapiens
215 MYBBP1A 10514
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
216 RPL11 6135
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
217 Brwd3  
Affinity Capture-MS Mus musculus
218 RPL23A 6147
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
219 SLX4  
Affinity Capture-MS Homo sapiens
220 METTL14  
Affinity Capture-MS Homo sapiens
221 ECT2 1894
Affinity Capture-MS Homo sapiens
222 TRAF3IP1 26146
Affinity Capture-MS Homo sapiens
223 EEF2 1938
Co-fractionation Homo sapiens
224 RPL14 9045
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
225 RPL21 6144
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
226 ZC3H8  
Affinity Capture-MS Homo sapiens
227 ACE2 59272
Affinity Capture-MS Homo sapiens
228 NCAPH 23397
Affinity Capture-MS Homo sapiens
229 NEFL 4747
Cross-Linking-MS (XL-MS) Homo sapiens
230 PSPC1 55269
Affinity Capture-MS Homo sapiens
231 RPS13 6207
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
232 RPS14 6208
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
233 RPL12 6136
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
234 RPL22 6146
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
235 MATR3 9782
Co-fractionation Homo sapiens
236 RPL18 6141
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
237 RNF2  
Affinity Capture-MS Homo sapiens
238 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
239 RPL3L 6123
Co-fractionation Homo sapiens
240 RPS25 6230
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
241 SMN1 6606
Affinity Capture-MS Homo sapiens
242 FBXL6  
Affinity Capture-MS Homo sapiens
243 RPL6 6128
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
244 RPS21 6227
Co-fractionation Homo sapiens
245 USP36  
Affinity Capture-MS Homo sapiens
246 RPA1 6117
Affinity Capture-MS Homo sapiens
247 HNRNPM 4670
Co-fractionation Homo sapiens
248 MTHFD1 4522
Co-fractionation Homo sapiens
249 ZNF7  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
250 HDAC5 10014
Affinity Capture-MS Homo sapiens
251 RPL34 6164
Co-fractionation Homo sapiens
252 PDZD8 118987
Affinity Capture-MS Homo sapiens
253 UFL1 23376
Affinity Capture-MS Homo sapiens
254 TRIM37  
Proximity Label-MS Homo sapiens
255 RPL38 6169
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
256 API5 8539
Affinity Capture-MS Homo sapiens
257 RNPS1 10921
Co-fractionation Homo sapiens
258 RPS7 6201
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
259 RPL8 6132
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
260 RPL28 6158
Co-fractionation Homo sapiens
261 RPS27L 51065
Co-fractionation Homo sapiens
262 RPL36AL 6166
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
263 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
264 UBE2H 7328
Affinity Capture-MS Homo sapiens
265 RPS12 6206
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
266 RIT1 6016
Negative Genetic Homo sapiens
267 LGR4 55366
Affinity Capture-MS Homo sapiens
268 RPS3A 6189
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
269 RPL30 6156
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
270 PPIE 10450
Affinity Capture-MS Homo sapiens
271 RPL13A 23521
Co-fractionation Homo sapiens
272 RPL37A 6168
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
273 NGRN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
274 RPL10 6134
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
275 RPL15 6138
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
276 DNAJC25 548645
Affinity Capture-MS Homo sapiens
277 DNAJC15  
Affinity Capture-MS Homo sapiens
278 ILF2 3608
Co-fractionation Homo sapiens
279 PPP1CC 5501
Two-hybrid Homo sapiens
280 TOP2A 7153
Affinity Capture-MS Homo sapiens
281 RPS20 6224
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
282 TGFB1 7040
Affinity Capture-MS Homo sapiens
283 COPS5 10987
Affinity Capture-MS Homo sapiens
284 FBXW7  
Affinity Capture-MS Homo sapiens
285 RPL24 6152
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
286 RPS8 6202
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
287 WDR12 55759
Co-fractionation Homo sapiens
288 ABCE1 6059
Co-fractionation Homo sapiens
289 ADARB1 104
Affinity Capture-MS Homo sapiens
290 PRKRA 8575
Affinity Capture-MS Homo sapiens
291 DNAJC16  
Affinity Capture-MS Homo sapiens
292 EED  
Affinity Capture-MS Homo sapiens
293 SRP68 6730
Affinity Capture-MS Homo sapiens
294 KIF2C 11004
Affinity Capture-MS Homo sapiens
295 CDC73  
Affinity Capture-MS Homo sapiens
296 MYCN  
Affinity Capture-MS Homo sapiens
297 MAD2L2 10459
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
298 CTCF  
Affinity Capture-MS Homo sapiens
299 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
300 SETD8  
Affinity Capture-MS Homo sapiens
301 RPS23 6228
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
302 SRP9 6726
Affinity Capture-MS Homo sapiens
303 STAU1 6780
Affinity Capture-MS Homo sapiens
304 SRSF6 6431
Affinity Capture-MS Homo sapiens
305 ZNF22  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
306 UBE2I 7329
Biochemical Activity Homo sapiens
307 VCP 7415
Affinity Capture-MS Homo sapiens
308 IFI16 3428
Affinity Capture-MS Homo sapiens
309 RPL27A 6157
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
310 PML 5371
Affinity Capture-MS Homo sapiens
311 RPS15A 6210
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
312 GLTSCR2  
Affinity Capture-MS Homo sapiens
313 SPPL3  
Affinity Capture-MS Homo sapiens
314 USP38 84640
Affinity Capture-MS Homo sapiens
315 IPO5 3843
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
316 RPLP2 6181
Co-fractionation Homo sapiens
317 FANCD2  
Affinity Capture-MS Homo sapiens
318 RPL23 9349
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
319 DNAJC2 27000
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
320 RPL35 11224
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
321 TSPYL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
322 RLIM 51132
Affinity Capture-MS Homo sapiens
323 Rrbp1  
Affinity Capture-MS Mus musculus
324 RPL3 6122
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
325 CBX2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
326 AURKB 9212
Affinity Capture-MS Homo sapiens
327 IL7R  
Protein-RNA Homo sapiens
328 DKC1 1736
Affinity Capture-MS Homo sapiens
329 NIN 51199
Proximity Label-MS Homo sapiens
330 INO80B 83444
Affinity Capture-MS Homo sapiens
331 SIRT2 22933
Affinity Capture-MS Homo sapiens
332 DYRK2 8445
Affinity Capture-MS Homo sapiens
333 KRAS 3845
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
334 BMP4 652
Affinity Capture-MS Homo sapiens
335 GNB2L1 10399
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
336 CCDC8  
Affinity Capture-MS Homo sapiens
337 ARRB2 409
Affinity Capture-MS Homo sapiens
338 ZNF689  
Affinity Capture-MS Homo sapiens
339 DNAJC19 131118
Affinity Capture-MS Homo sapiens
340 TUBG1 7283
Affinity Capture-MS Homo sapiens
341 ZNF746  
Affinity Capture-MS Homo sapiens
342 CUL5 8065
Affinity Capture-MS Homo sapiens
343 RPS15 6209
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
344 SRP72 6731
Affinity Capture-MS Homo sapiens
345 NSA2  
Affinity Capture-MS Homo sapiens
346 EIF4A3 9775
Affinity Capture-MS Homo sapiens
347 THAP7  
Affinity Capture-MS Homo sapiens
348 RPS28 6234
Co-fractionation Homo sapiens
349 MRPL13  
Affinity Capture-MS Homo sapiens
350 TRIP4 9325
Affinity Capture-MS Homo sapiens
351 TRIM31  
Affinity Capture-MS Homo sapiens
352 PINK1  
Affinity Capture-MS Homo sapiens
353 RPS6 6194
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
354 GRSF1 2926
Proximity Label-MS Homo sapiens
355 DNAJC1 64215
Affinity Capture-MS Homo sapiens
356 HNRNPU 3192
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
357 C9orf72  
Affinity Capture-MS Homo sapiens
358 RPL17 6139
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which RPL7 is involved
PathwayEvidenceSource
Axon guidance IEA Reactome
Cap-dependent Translation Initiation TAS Reactome
Cellular response to starvation IEA Reactome
Cellular responses to stimuli IEA Reactome
Cellular responses to stress IEA Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Eukaryotic Translation Elongation IEA Reactome
Eukaryotic Translation Initiation TAS Reactome
Eukaryotic Translation Termination IEA Reactome
Formation of a pool of free 40S subunits TAS Reactome
GTP hydrolysis and joining of the 60S ribosomal subunit TAS Reactome
Infectious disease TAS Reactome
Influenza Infection TAS Reactome
Influenza Viral RNA Transcription and Replication TAS Reactome
L13a-mediated translational silencing of Ceruloplasmin expression TAS Reactome
Major pathway of rRNA processing in the nucleolus and cytosol TAS Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome
Metabolism of proteins TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of RNA TAS Reactome
Nervous system development IEA Reactome
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) TAS Reactome
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) TAS Reactome
Nonsense-Mediated Decay (NMD) TAS Reactome
Peptide chain elongation IEA Reactome
Regulation of expression of SLITs and ROBOs IEA Reactome
Response of EIF2AK4 (GCN2) to amino acid deficiency IEA Reactome
rRNA processing TAS Reactome
rRNA processing in the nucleus and cytosol TAS Reactome
Selenoamino acid metabolism IEA Reactome
Selenocysteine synthesis IEA Reactome
Signaling by ROBO receptors IEA Reactome
SRP-dependent cotranslational protein targeting to membrane IEA Reactome
SRP-dependent cotranslational protein targeting to membrane TAS Reactome
Translation TAS Reactome
Translation IEA Reactome
Viral Infection Pathways TAS Reactome
Viral mRNA Translation TAS Reactome





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