Gene description for TUBGCP4
Gene name tubulin, gamma complex associated protein 4
Gene symbol TUBGCP4
Other names/aliases 76P
GCP-4
GCP4
Grip76
MCCRP3
Species Homo sapiens
 Database cross references - TUBGCP4
ExoCarta ExoCarta_27229
Entrez Gene 27229
HGNC 16691
MIM 609610
UniProt Q9UGJ1  
 TUBGCP4 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for TUBGCP4
Molecular Function
    structural constituent of cytoskeleton GO:0005200 NAS
    protein binding GO:0005515 IPI
Biological Process
    protein complex assembly GO:0006461 NAS
    microtubule nucleation GO:0007020 NAS
    mitotic cell cycle GO:0000278 TAS
    G2/M transition of mitotic cell cycle GO:0000086 TAS
Subcellular Localization
    gamma-tubulin ring complex GO:0008274 NAS
    microtubule GO:0005874 IEA
    recycling endosome GO:0055037 IDA
    centrosome GO:0005813 IDA
    spindle pole GO:0000922 IEA
    membrane GO:0016020 IDA
    cytosol GO:0005829 TAS
    microtubule cytoskeleton GO:0015630 TAS
 Experiment description of studies that identified TUBGCP4 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TUBGCP4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MAD1L1  
Two-hybrid Homo sapiens
2 DIPA  
Two-hybrid Homo sapiens
3 KRT18 3875
Two-hybrid Homo sapiens
4 GOLGA2 2801
Two-hybrid Homo sapiens
5 KRT15 3866
Two-hybrid Homo sapiens
6 AP2B1 163
Two-hybrid Homo sapiens
7 FBF1  
Two-hybrid Homo sapiens
8 PAK7  
Two-hybrid Homo sapiens
9 USHBP1  
Two-hybrid Homo sapiens
10 VIM 7431
Two-hybrid Homo sapiens
11 KCTD17  
Two-hybrid Homo sapiens
12 NURIT  
Two-hybrid Homo sapiens
13 RPRD1B 58490
Two-hybrid Homo sapiens
14 GFAP 2670
Two-hybrid Homo sapiens
15 OBFC1 79991
Two-hybrid Homo sapiens
16 SDSL  
Two-hybrid Homo sapiens
View the network image/svg+xml



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