Gene description for C16orf58
Gene name chromosome 16 open reading frame 58
Gene symbol C16orf58
Other names/aliases RUS
Species Homo sapiens
 Database cross references - C16orf58
ExoCarta ExoCarta_64755
Vesiclepedia VP_64755
Entrez Gene 64755
HGNC 25848
UniProt Q96GQ5  
 C16orf58 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for C16orf58
Molecular Function
    protein binding GO:0005515 IPI
Subcellular Localization
    membrane GO:0016020 HDA
 Experiment description of studies that identified C16orf58 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for C16orf58
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RNF149 284996
Affinity Capture-MS Homo sapiens
2 TGOLN2 10618
Affinity Capture-MS Homo sapiens
3 SPATS2  
Affinity Capture-MS Homo sapiens
4 RAMP3  
Affinity Capture-MS Homo sapiens
5 RBMXL1  
Affinity Capture-MS Homo sapiens
6 GJD3  
Proximity Label-MS Homo sapiens
7 LYPD3 27076
Affinity Capture-MS Homo sapiens
8 SLC10A6  
Two-hybrid Homo sapiens
9 SYNGR1 9145
Affinity Capture-MS Homo sapiens
10 MTX1 4580
Affinity Capture-MS Homo sapiens
11 SLC10A1  
Two-hybrid Homo sapiens
12 ESF1 51575
Affinity Capture-MS Homo sapiens
13 FPR1  
Affinity Capture-MS Homo sapiens
14 TMEM9B 56674
Affinity Capture-MS Homo sapiens
15 DHRSX 207063
Two-hybrid Homo sapiens
16 IFNGR1 3459
Affinity Capture-MS Homo sapiens
17 KLRB1  
Affinity Capture-MS Homo sapiens
18 BMPR1A 657
Affinity Capture-MS Homo sapiens
19 FFAR1  
Affinity Capture-MS Homo sapiens
20 SLC22A9  
Affinity Capture-MS Homo sapiens
21 LRP10 26020
Affinity Capture-MS Homo sapiens
22 TCEB3 6924
Affinity Capture-MS Homo sapiens
23 ARL6IP6  
Two-hybrid Homo sapiens
24 RNF5  
Two-hybrid Homo sapiens
25 TMEM120A 83862
Affinity Capture-MS Homo sapiens
26 SLC30A8  
Two-hybrid Homo sapiens
27 ELOVL2  
Affinity Capture-MS Homo sapiens
28 HLA-B 3106
Affinity Capture-MS Homo sapiens
29 GINM1 116254
Affinity Capture-MS Homo sapiens
30 GPR55  
Affinity Capture-MS Homo sapiens
31 RAB21 23011
Affinity Capture-MS Homo sapiens
32 DGAT2L6  
Two-hybrid Homo sapiens
33 ACVR2B  
Affinity Capture-MS Homo sapiens
34 CENPU  
Affinity Capture-MS Homo sapiens
35 PGRMC2 10424
Two-hybrid Homo sapiens
36 METTL7B  
Affinity Capture-MS Homo sapiens
37 TNFSF9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 UFSP2 55325
Affinity Capture-MS Homo sapiens
39 F2RL1  
Affinity Capture-MS Homo sapiens
40 DFNA5 1687
Affinity Capture-MS Homo sapiens
41 SDCBP 6386
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 FGFR1 2260
Affinity Capture-MS Homo sapiens
43 RAVER1 125950
Affinity Capture-MS Homo sapiens
44 SSMEM1  
Two-hybrid Homo sapiens
45 CLDND1 56650
Affinity Capture-MS Homo sapiens
46 CHST12 55501
Affinity Capture-MS Homo sapiens
47 KLK1 3816
Affinity Capture-MS Homo sapiens
48 NDFIP1 80762
Affinity Capture-MS Homo sapiens
49 SQLE 6713
Affinity Capture-MS Homo sapiens
50 XPO1 7514
Affinity Capture-MS Homo sapiens
51 TMEM248 55069
Two-hybrid Homo sapiens
52 FCER1G 2207
Two-hybrid Homo sapiens
53 CANT1 124583
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 ADPGK 83440
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 FAM219A 203259
Affinity Capture-MS Homo sapiens
56 SFXN3 81855
Two-hybrid Homo sapiens
57 TUBGCP4 27229
Affinity Capture-MS Homo sapiens
58 PDCD1LG2 80380
Two-hybrid Homo sapiens
59 GPR35  
Affinity Capture-MS Homo sapiens
60 C6orf47  
Affinity Capture-MS Homo sapiens
61 UBE2I 7329
Two-hybrid Homo sapiens
62 ODF4  
Two-hybrid Homo sapiens
63 ZCCHC12  
Two-hybrid Homo sapiens
64 U2AF2 11338
Affinity Capture-MS Homo sapiens
65 IL10RA  
Two-hybrid Homo sapiens
66 NSRP1  
Affinity Capture-MS Homo sapiens
67 CREB3  
Two-hybrid Homo sapiens
68 LYPD1  
Affinity Capture-MS Homo sapiens
69 RPN1 6184
Proximity Label-MS Homo sapiens
70 C5orf46 389336
Two-hybrid Homo sapiens
71 TEX29  
Two-hybrid Homo sapiens
72 PTPRS 5802
Affinity Capture-MS Homo sapiens
73 SCN3B  
Two-hybrid Homo sapiens
74 MZT2B 80097
Affinity Capture-MS Homo sapiens
75 SYNGR3  
Affinity Capture-MS Homo sapiens
76 ADCK1  
Affinity Capture-MS Homo sapiens
77 TMEM35  
Two-hybrid Homo sapiens
78 GJA8  
Two-hybrid Homo sapiens
79 CD320 51293
Affinity Capture-MS Homo sapiens
80 ACVR2A  
Affinity Capture-MS Homo sapiens
81 APLNR  
Affinity Capture-MS Homo sapiens
82 RPN2 6185
Proximity Label-MS Homo sapiens
83 ICAM2 3384
Affinity Capture-MS Homo sapiens
84 FFAR2  
Two-hybrid Homo sapiens
85 NRSN2  
Affinity Capture-MS Homo sapiens
86 RAB9B 51209
Affinity Capture-MS Homo sapiens
87 GLMN 11146
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 MAD1L1  
Affinity Capture-MS Homo sapiens
89 MS4A4A  
Two-hybrid Homo sapiens
90 HSD17B11 51170
Proximity Label-MS Homo sapiens
91 RTN4R 65078
Affinity Capture-MS Homo sapiens
92 GPR182  
Affinity Capture-MS Homo sapiens
93 ERGIC3 51614
Two-hybrid Homo sapiens
94 HSD3B7 80270
Proximity Label-MS Homo sapiens
95 FITM2  
Affinity Capture-MS Homo sapiens
96 NPY2R  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 TNPO3 23534
Affinity Capture-MS Homo sapiens
98 HSD17B13  
Two-hybrid Homo sapiens
99 AQP3  
Affinity Capture-MS Homo sapiens
100 NELFA  
Affinity Capture-MS Homo sapiens
101 CREB3L1  
Two-hybrid Homo sapiens
102 SPCS3 60559
Affinity Capture-MS Homo sapiens
103 XPO6 23214
Affinity Capture-MS Homo sapiens
104 FAM209A 200232
Two-hybrid Homo sapiens
105 GPR42  
Two-hybrid Homo sapiens
106 FAM134C 162427
Two-hybrid Homo sapiens
107 BMPR2 659
Affinity Capture-MS Homo sapiens
108 TMEM237 65062
Two-hybrid Homo sapiens
109 ATP2A1 487
Proximity Label-MS Homo sapiens
110 RELT  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
111 GPR45  
Affinity Capture-MS Homo sapiens
112 CMTM5  
Two-hybrid Homo sapiens
113 RAB9A 9367
Affinity Capture-MS Homo sapiens
114 PLIN3 10226
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 TMEM9 252839
Affinity Capture-MS Homo sapiens
116 SLC35E3  
Two-hybrid Homo sapiens
117 DIDO1  
Affinity Capture-MS Homo sapiens
118 STX10 8677
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 LPPR2  
Affinity Capture-MS Homo sapiens
120 VIMP 55829
Affinity Capture-MS Homo sapiens
121 P2RY8  
Affinity Capture-MS Homo sapiens
122 EPHB3 2049
Affinity Capture-MS Homo sapiens
123 MARC1  
Affinity Capture-MS Homo sapiens
124 ZDHHC15 158866
Two-hybrid Homo sapiens
125 ITGAM 3684
Two-hybrid Homo sapiens
126 TMX2 51075
Two-hybrid Homo sapiens
127 PSCA 8000
Two-hybrid Homo sapiens
128 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
129 NAAA  
Affinity Capture-MS Homo sapiens
130 PRRC2A 7916
Affinity Capture-MS Homo sapiens
131 EDNRA 1909
Affinity Capture-MS Homo sapiens
132 GLRA2  
Affinity Capture-MS Homo sapiens
133 GP9 2815
Affinity Capture-MS Homo sapiens
134 OPALIN  
Affinity Capture-MS Homo sapiens
135 MFSD4  
Affinity Capture-MS Homo sapiens
136 WBP11  
Affinity Capture-MS Homo sapiens
137 EHHADH 1962
Two-hybrid Homo sapiens
138 TNFSF14  
Affinity Capture-MS Homo sapiens
139 TMEM214 54867
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 TMEM120B  
Affinity Capture-MS Homo sapiens
141 DNAAF5 54919
Affinity Capture-MS Homo sapiens
142 UGCG 7357
Affinity Capture-MS Homo sapiens
143 TUBGCP2 10844
Affinity Capture-MS Homo sapiens
144 EBP  
Two-hybrid Homo sapiens
145 LHFPL5  
Two-hybrid Homo sapiens
146 ARFIP2 23647
Affinity Capture-MS Homo sapiens
147 MMGT1 93380
Two-hybrid Homo sapiens
148 GPR50  
Affinity Capture-MS Homo sapiens
149 UBB 7314
Affinity Capture-MS Homo sapiens
150 TERF1 7013
Affinity Capture-MS Homo sapiens
151 OTUD4  
Affinity Capture-MS Homo sapiens
152 SEC62 7095
Proximity Label-MS Homo sapiens
153 SLC25A51  
Affinity Capture-MS Homo sapiens
154 DHX38 9785
Affinity Capture-MS Homo sapiens
155 CISD2 493856
Two-hybrid Homo sapiens
156 VIPR1  
Affinity Capture-MS Homo sapiens
157 ZC3H13 23091
Affinity Capture-MS Homo sapiens
158 ALG11  
Affinity Capture-MS Homo sapiens
159 ADIPOR1 51094
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 VPS8 23355
Affinity Capture-MS Homo sapiens
161 LAPTM4A 9741
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
162 MAP1LC3B2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which C16orf58 is involved
No pathways found





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