Gene description for BMPR2
Gene name	bone morphogenetic protein receptor, type II (serine/threonine kinase)
Gene symbol	BMPR2
Other names/aliases	BMPR-II BMPR3 BMR2 BRK-3 POVD1 PPH1 T-ALK
Species	Homo sapiens
Database cross references - BMPR2
ExoCarta	ExoCarta_659
Entrez Gene	659
HGNC	1078
MIM	600799
UniProt	Q13873
BMPR2 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for BMPR2

Molecular Function     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     activin receptor activity, type II GO:0016362 TAS     metal ion binding GO:0046872 IEA     receptor signaling protein serine/threonine kinase activity GO:0004702 IEA     BMP binding GO:0036122 IPI     growth factor binding GO:0019838 IEA Biological Process     regulation of lung blood pressure GO:0014916 ISS     anterior/posterior pattern specification GO:0009952 ISS     negative regulation of systemic arterial blood pressure GO:0003085 IMP     positive regulation of endothelial cell proliferation GO:0001938 IMP     positive regulation of BMP signaling pathway GO:0030513 IMP     negative regulation of chondrocyte proliferation GO:1902731 IMP     BMP signaling pathway GO:0030509 TAS     chondrocyte development GO:0002063 IMP     endothelial cell proliferation GO:0001935 IMP     vascular endothelial growth factor receptor signaling pathway GO:0048010 ISS     blood vessel remodeling GO:0001974 ISS     retina vasculature development in camera-type eye GO:0061298 ISS     positive regulation of axon extension involved in axon guidance GO:0048842 IEA     limb development GO:0060173 IEA     endothelial cell apoptotic process GO:0072577 IMP     cellular response to starvation GO:0009267 IEP     positive regulation of osteoblast differentiation GO:0045669 IMP     negative regulation of vasoconstriction GO:0045906 ISS     positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 IMP     lymphatic endothelial cell differentiation GO:0060836 ISS     activin receptor signaling pathway GO:0032924 TAS     positive regulation of cartilage development GO:0061036 ISS     transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 IDA     negative regulation of DNA biosynthetic process GO:2000279 IMP     proteoglycan biosynthetic process GO:0030166 ISS     artery development GO:0060840 ISS     regulation of cell proliferation GO:0042127 IMP     negative regulation of cell growth GO:0030308 IDA     lung alveolus development GO:0048286 ISS     brain development GO:0007420 IEA     positive regulation of endothelial cell migration GO:0010595 IMP     venous blood vessel development GO:0060841 ISS     endochondral bone morphogenesis GO:0060350 ISS     mesoderm formation GO:0001707 ISS     lymphangiogenesis GO:0001946 ISS     transcription from RNA polymerase II promoter GO:0006366 IMP     positive regulation of epithelial cell migration GO:0010634 IDA     signal transduction by protein phosphorylation GO:0023014 IEA     positive regulation of bone mineralization GO:0030501 IMP Subcellular Localization     dendrite GO:0030425 IEA     integral component of plasma membrane GO:0005887 IDA     caveola GO:0005901 IMP     spanning component of plasma membrane GO:0044214 TAS     neuronal cell body GO:0043025 IEA     plasma membrane GO:0005886 TAS     cell surface GO:0009986 IEA     extracellular space GO:0005615 IDA     cytoplasm GO:0005737 IEA     apical plasma membrane GO:0016324 IEA     basal plasma membrane GO:0009925 IEA