Gene description for RPS15
Gene name ribosomal protein S15
Gene symbol RPS15
Other names/aliases RIG
S15
Species Homo sapiens
 Database cross references - RPS15
ExoCarta ExoCarta_6209
Vesiclepedia VP_6209
Entrez Gene 6209
HGNC 10388
MIM 180535
UniProt P62841  
 RPS15 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for RPS15
Molecular Function
    DNA binding GO:0003677 NAS
    RNA binding GO:0003723 HDA
    structural constituent of ribosome GO:0003735 HDA
    structural constituent of ribosome GO:0003735 IBA
    structural constituent of ribosome GO:0003735 IDA
    structural constituent of ribosome GO:0003735 IMP
    protein binding GO:0005515 IPI
    MDM2/MDM4 family protein binding GO:0097371 IPI
    ubiquitin ligase inhibitor activity GO:1990948 IDA
Biological Process
    ribosomal small subunit assembly GO:0000028 IBA
    ribosomal small subunit export from nucleus GO:0000056 IMP
    osteoblast differentiation GO:0001649 HDA
    cytoplasmic translation GO:0002181 IC
    cytoplasmic translation GO:0002181 NAS
    rRNA processing GO:0006364 IMP
    translation GO:0006412 IC
    ribosomal small subunit biogenesis GO:0042274 IMP
    positive regulation of signal transduction by p53 class mediator GO:1901798 IDA
Subcellular Localization
    nucleus GO:0005634 NAS
    nucleoplasm GO:0005654 NAS
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 NAS
    cytosol GO:0005829 TAS
    focal adhesion GO:0005925 HDA
    membrane GO:0016020 HDA
    cytosolic ribosome GO:0022626 IDA
    cytosolic small ribosomal subunit GO:0022627 HDA
    cytosolic small ribosomal subunit GO:0022627 IBA
    cytosolic small ribosomal subunit GO:0022627 IDA
    cytosolic small ribosomal subunit GO:0022627 NAS
 Experiment description of studies that identified RPS15 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
19
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
20
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
24
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
27
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for RPS15
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPSA 3921
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
2 RALY 22913
Cross-Linking-MS (XL-MS) Homo sapiens
3 SRP19 6728
Affinity Capture-MS Homo sapiens
4 PTPRG 5793
Proximity Label-MS Homo sapiens
5 MRPS27 23107
Affinity Capture-MS Homo sapiens
6 RPSAP58 388524
Affinity Capture-MS Homo sapiens
7 UBE2H 7328
Affinity Capture-MS Homo sapiens
8 LUZP4  
Affinity Capture-MS Homo sapiens
9 HDAC4  
Affinity Capture-MS Homo sapiens
10 RPL26L1 51121
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
11 NOLC1 9221
Cross-Linking-MS (XL-MS) Homo sapiens
12 RPS28 6234
Co-fractionation Homo sapiens
13 RPS11 6205
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
14 COPG2 26958
Cross-Linking-MS (XL-MS) Homo sapiens
15 RPS3A 6189
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
16 NDUFS1 4719
Co-fractionation Homo sapiens
17 TNFAIP3 7128
Two-hybrid Homo sapiens
18 SMURF1 57154
Affinity Capture-MS Homo sapiens
19 RPL30 6156
Co-fractionation Homo sapiens
20 RPS17 6218
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
21 ZNF324B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 ZNF668  
Affinity Capture-MS Homo sapiens
23 NEB 4703
Cross-Linking-MS (XL-MS) Homo sapiens
24 HIST1H1D 3007
Affinity Capture-MS Homo sapiens
25 BTF3 689
Affinity Capture-MS Homo sapiens
26 RPL13A 23521
Affinity Capture-MS Homo sapiens
27 RAB35 11021
Cross-Linking-MS (XL-MS) Homo sapiens
28 THAP3  
Affinity Capture-MS Homo sapiens
29 EBNA-LP  
Affinity Capture-MS
30 KLF8  
Affinity Capture-MS Homo sapiens
31 RPL37A 6168
Co-fractionation Homo sapiens
32 RPS19 6223
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
33 RPL10 6134
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
34 MRPL24  
Co-fractionation Homo sapiens
35 RPL14 9045
Co-fractionation Homo sapiens
36 SSB 6741
Affinity Capture-MS Homo sapiens
37 RIOK3 8780
Affinity Capture-MS Homo sapiens
38 MRPL23 6150
Co-fractionation Homo sapiens
39 CAND1 55832
Affinity Capture-MS Homo sapiens
40 SRP72 6731
Affinity Capture-MS Homo sapiens
41 PDZD8 118987
Affinity Capture-MS Homo sapiens
42 ASPH 444
Cross-Linking-MS (XL-MS) Homo sapiens
43 SOX2  
Affinity Capture-MS Homo sapiens
44 H2AFV 94239
Cross-Linking-MS (XL-MS) Homo sapiens
45 FAU 2197
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
46 CADM1 23705
Co-fractionation Homo sapiens
47 GSK3A 2931
Two-hybrid Homo sapiens
48 ATG13 9776
Affinity Capture-MS Homo sapiens
49 RPS18 6222
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
50 PTRH2 51651
Co-fractionation Homo sapiens
51 CAPZB 832
Affinity Capture-MS Homo sapiens
52 MEPCE 56257
Affinity Capture-MS Homo sapiens
53 SART3 9733
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 RNPS1 10921
Co-fractionation Homo sapiens
55 PRR11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 B3GNT2 10678
Affinity Capture-MS Homo sapiens
57 PRC1 9055
Affinity Capture-MS Homo sapiens
58 LLPH  
Affinity Capture-MS Homo sapiens
59 KIF23 9493
Affinity Capture-MS Homo sapiens
60 UBE2O 63893
Affinity Capture-MS Homo sapiens
61 ATP6V0A1 535
Co-fractionation Homo sapiens
62 CDK2AP1  
Affinity Capture-MS Homo sapiens
63 EIF3B 8662
Affinity Capture-MS Homo sapiens
64 COPS5 10987
Affinity Capture-MS Homo sapiens
65 FBXW7  
Affinity Capture-MS Homo sapiens
66 RPL24 6152
Co-fractionation Homo sapiens
67 DUSP11  
Affinity Capture-MS Homo sapiens
68 BHLHA15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 NPM1 4869
Affinity Capture-MS Homo sapiens
70 SRRM2 23524
Cross-Linking-MS (XL-MS) Homo sapiens
71 HSPH1 10808
Cross-Linking-MS (XL-MS) Homo sapiens
72 RPS8 6202
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
73 DUSP5  
Affinity Capture-MS Homo sapiens
74 RPS9 6203
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
75 GSPT1 2935
Affinity Capture-MS Homo sapiens
76 RBM4B  
Affinity Capture-MS Homo sapiens
77 FAM207A  
Co-crystal Structure Homo sapiens
78 PRKRA 8575
Affinity Capture-MS Homo sapiens
79 UGGT1 56886
Cross-Linking-MS (XL-MS) Homo sapiens
80 HIST2H2AC 8338
Affinity Capture-MS Homo sapiens
81 PLA2G12A  
Two-hybrid Homo sapiens
82 SRP68 6730
Affinity Capture-MS Homo sapiens
83 KLF4  
Affinity Capture-MS Homo sapiens
84 CEP135  
Cross-Linking-MS (XL-MS) Homo sapiens
85 HIST1H4I 8294
Affinity Capture-MS Homo sapiens
86 MTDH 92140
Cross-Linking-MS (XL-MS) Homo sapiens
87 ZNF346  
Affinity Capture-MS Homo sapiens
88 Eif3a 13669
Affinity Capture-MS Mus musculus
89 CUL1 8454
Affinity Capture-MS Homo sapiens
90 MYCN  
Affinity Capture-MS Homo sapiens
91 RBM42  
Affinity Capture-MS Homo sapiens
92 FGF17  
Affinity Capture-MS Homo sapiens
93 MAK16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 RPL19 6143
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
95 GSK3B 2932
Two-hybrid Homo sapiens
96 KIF14 9928
Affinity Capture-MS Homo sapiens
97 RPL10L 140801
Co-fractionation Homo sapiens
98 LIN28A  
Affinity Capture-MS Homo sapiens
99 CPEB1  
Affinity Capture-MS Homo sapiens
100 KLF16  
Affinity Capture-MS Homo sapiens
101 EPB41L3 23136
Affinity Capture-MS Homo sapiens
102 RPS23 6228
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
103 KLF5  
Affinity Capture-MS Homo sapiens
104 SRP9 6726
Affinity Capture-MS Homo sapiens
105 TLX1  
Affinity Capture-MS Homo sapiens
106 MPV17 4358
Co-fractionation Homo sapiens
107 MRPL11 65003
Cross-Linking-MS (XL-MS) Homo sapiens
108 FOXA1  
Affinity Capture-MS Homo sapiens
109 TSR1 55720
Affinity Capture-MS Homo sapiens
110 SHPRH  
Cross-Linking-MS (XL-MS) Homo sapiens
111 DDX21 9188
Affinity Capture-MS Homo sapiens
112 LIN28B  
Affinity Capture-MS Homo sapiens
113 RPL9 6133
Co-fractionation Homo sapiens
114 RPL4 6124
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
115 G2E3  
Two-hybrid Homo sapiens
116 ZC3H3  
Affinity Capture-MS Homo sapiens
117 SERINC3 10955
Two-hybrid Homo sapiens
118 RPS10 6204
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
119 HIST1H1B 3009
Affinity Capture-MS Homo sapiens
120 SRSF3 6428
Affinity Capture-MS Homo sapiens
121 YBX2 51087
Affinity Capture-MS Homo sapiens
122 DNAJC2 27000
Affinity Capture-MS Homo sapiens
123 SRSF6 6431
Affinity Capture-MS Homo sapiens
124 PURG  
Affinity Capture-MS Homo sapiens
125 ZBTB48  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 PSIP1 11168
Cross-Linking-MS (XL-MS) Homo sapiens
127 VRK1 7443
Affinity Capture-MS Homo sapiens
128 RPL5 6125
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
129 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
130 SRSF4 6429
Affinity Capture-MS Homo sapiens
131 RPL18A 6142
Co-fractionation Homo sapiens
132 Srp72  
Affinity Capture-MS Mus musculus
133 CHMP4B 128866
Affinity Capture-MS Homo sapiens
134 FUBP1 8880
Co-fractionation Homo sapiens
135 STK10 6793
Cross-Linking-MS (XL-MS) Homo sapiens
136 FGF8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 CBX5 23468
Cross-Linking-MS (XL-MS) Homo sapiens
138 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 REXO4  
Affinity Capture-MS Homo sapiens
140 FBXL6  
Affinity Capture-MS Homo sapiens
141 DDX10  
Cross-Linking-MS (XL-MS) Homo sapiens
142 RPL36 25873
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
143 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
144 MRPL3  
Co-fractionation Homo sapiens
145 RPLP1 6176
Co-fractionation Homo sapiens
146 RPL15 6138
Co-fractionation Homo sapiens
147 RPS6 6194
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
148 RPLP0 6175
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
149 CEP76  
Affinity Capture-MS Homo sapiens
150 RAPGEF1 2889
Two-hybrid Homo sapiens
151 MAGEB2 4113
Affinity Capture-MS Homo sapiens
152 TRIM31  
Affinity Capture-MS Homo sapiens
153 C1orf131  
Affinity Capture-MS Homo sapiens
154 ZC3H15 55854
Cross-Linking-MS (XL-MS) Homo sapiens
155 RPS15A 6210
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
156 RPS29 6235
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
157 FGF13  
Affinity Capture-MS Homo sapiens
158 CYLD  
Affinity Capture-MS Homo sapiens
159 GLTSCR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 MRPL2 51069
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
161 HMGB2 3148
Affinity Capture-MS Homo sapiens
162 C7orf50 84310
Affinity Capture-MS Homo sapiens
163 H1FNT  
Affinity Capture-MS Homo sapiens
164 RPL11 6135
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
165 SP1  
Affinity Capture-MS Homo sapiens
166 RSL1D1 26156
Affinity Capture-MS Homo sapiens
167 NPM3 10360
Affinity Capture-MS Homo sapiens
168 ANLN 54443
Affinity Capture-MS Homo sapiens
169 METAP2 10988
Affinity Capture-MS Homo sapiens
170 FGFBP1 9982
Affinity Capture-MS Homo sapiens
171 MRPL14 64928
Co-fractionation Homo sapiens
172 EIF3G 8666
Affinity Capture-MS Homo sapiens
173 TMPO 7112
Affinity Capture-MS Homo sapiens
174 RPL32 6161
Co-fractionation Homo sapiens
175 RPL31 6160
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
176 RPLP2 6181
Co-fractionation Homo sapiens
177 ABT1 29777
Affinity Capture-MS Homo sapiens
178 RPL23 9349
Co-fractionation Homo sapiens
179 RPS2 6187
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
180 KIF20A 10112
Affinity Capture-MS Homo sapiens
181 RC3H2  
Affinity Capture-MS Homo sapiens
182 ECT2 1894
Affinity Capture-MS Homo sapiens
183 SIRT7  
Affinity Capture-MS Homo sapiens
184 DCAF13 25879
Affinity Capture-MS Homo sapiens
185 RPL35 11224
Affinity Capture-MS Homo sapiens
186 RPS12 6206
Co-fractionation Homo sapiens
187 SRSF1 6426
Affinity Capture-MS Homo sapiens
188 SRSF5 6430
Affinity Capture-MS Homo sapiens
189 PRDX1 5052
Cross-Linking-MS (XL-MS) Homo sapiens
190 SNX27 81609
Affinity Capture-MS Homo sapiens
191 ATP6V1D 51382
Co-fractionation Homo sapiens
192 CTCF  
Affinity Capture-MS Homo sapiens
193 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
194 CIT 11113
Affinity Capture-MS Homo sapiens
195 LRRC20  
Cross-Linking-MS (XL-MS) Homo sapiens
196 RPL21 6144
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
197 RPL3 6122
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
198 EGFR 1956
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
199 TCIRG1 10312
Co-fractionation Homo sapiens
200 H1F0 3005
Cross-Linking-MS (XL-MS) Homo sapiens
201 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 RPL37 6167
Co-fractionation Homo sapiens
203 SEC61A1 29927
Co-fractionation Homo sapiens
204 MYC  
Affinity Capture-MS Homo sapiens
205 RPL7 6129
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
206 PNMAL1  
Affinity Capture-MS Homo sapiens
207 FN1 2335
Affinity Capture-MS Homo sapiens
208 AURKB 9212
Affinity Capture-MS Homo sapiens
209 RPS27 6232
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
210 GIGYF2 26058
Cross-Linking-MS (XL-MS) Homo sapiens
211 PRR3  
Affinity Capture-MS Homo sapiens
212 NCAPH 23397
Affinity Capture-MS Homo sapiens
213 CBX6  
Affinity Capture-MS Homo sapiens
214 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
215 CDC5L 988
Cross-Linking-MS (XL-MS) Homo sapiens
216 PSPC1 55269
Affinity Capture-MS Homo sapiens
217 BAG1 573
Affinity Capture-MS Homo sapiens
218 RPS13 6207
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
219 KRR1 11103
Affinity Capture-MS Homo sapiens
220 RPS4Y1 6192
Affinity Capture-MS Homo sapiens
221 PABPC5 140886
Affinity Capture-MS Homo sapiens
222 RPS14 6208
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
223 PDGFB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
224 RPL35A 6165
Co-fractionation Homo sapiens
225 KLF15  
Affinity Capture-MS Homo sapiens
226 RPL22 6146
Co-fractionation Homo sapiens
227 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
228 MATR3 9782
Cross-Linking-MS (XL-MS) Homo sapiens
229 AMOT 154796
Cross-Linking-MS (XL-MS) Homo sapiens
230 RPL18 6141
Co-fractionation Homo sapiens
231 DDRGK1 65992
Affinity Capture-MS Homo sapiens
232 RNF2  
Affinity Capture-MS Homo sapiens
233 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
234 Rpl35 66489
Affinity Capture-MS Mus musculus
235 H2AFB2  
Affinity Capture-MS Homo sapiens
236 MDM4  
Affinity Capture-Western Homo sapiens
237 CCDC140  
Affinity Capture-MS Homo sapiens
238 Eif3e 16341
Affinity Capture-MS Mus musculus
239 HIST1H1T 3010
Affinity Capture-MS Homo sapiens
240 RPL26 6154
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
241 UPF2 26019
Two-hybrid Homo sapiens
242 ANK3  
Cross-Linking-MS (XL-MS) Homo sapiens
243 MDM2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
244 FLOT1 10211
Co-fractionation Homo sapiens
245 HUWE1 10075
Affinity Capture-MS Homo sapiens
246 RPS16 6217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
247 H2AFX 3014
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
248 PAIP1 10605
Affinity Capture-MS Homo sapiens
249 ZNF574  
Affinity Capture-MS Homo sapiens
250 CBX4  
Affinity Capture-MS Homo sapiens
251 AHSA1 10598
Affinity Capture-MS Homo sapiens
252 RPL13 6137
Co-fractionation Homo sapiens
253 BMPR2 659
Cross-Linking-MS (XL-MS) Homo sapiens
254 IKBKAP 8518
Cross-Linking-MS (XL-MS) Homo sapiens
255 SURF6  
Affinity Capture-MS Homo sapiens
256 MTCL1 23255
Cross-Linking-MS (XL-MS) Homo sapiens
257 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
258 RIT1 6016
Negative Genetic Homo sapiens
259 ALDOC 230
Cross-Linking-MS (XL-MS) Homo sapiens
260 RNF151  
Affinity Capture-MS Homo sapiens
261 RPS25 6230
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
262 HMGN4  
Affinity Capture-MS Homo sapiens
263 RPS3 6188
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
264 ILF3 3609
Affinity Capture-MS Homo sapiens
265 ZBTB47  
Affinity Capture-MS Homo sapiens
266 RRS1 23212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
267 TP53 7157
Affinity Capture-MS Homo sapiens
268 RPL6 6128
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
269 TUBG1 7283
Affinity Capture-MS Homo sapiens
270 ATP6V0A2 23545
Co-fractionation Homo sapiens
271 ICT1 3396
Co-fractionation Homo sapiens
272 APOBEC3D  
Affinity Capture-MS Homo sapiens
273 ZNF746  
Affinity Capture-MS Homo sapiens
274 ERCC8  
Affinity Capture-MS Homo sapiens
275 USP36  
Affinity Capture-MS Homo sapiens
276 ZNF169 169841
Affinity Capture-MS Homo sapiens
277 BYSL 705
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
278 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
279 RPS4X 6191
Reconstituted Complex Homo sapiens
280 RIOK1 83732
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
281 G3BP1 10146
Affinity Capture-MS Homo sapiens
282 ELAVL1 1994
Co-fractionation Homo sapiens
283 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
284 G3BP2 9908
Affinity Capture-MS Homo sapiens
285 H2AFB3  
Affinity Capture-MS Homo sapiens
286 RPS5 6193
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
287 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
288 RPL34 6164
Co-fractionation Homo sapiens
289 RPS26 6231
Co-fractionation Homo sapiens
290 DRG1 4733
Affinity Capture-MS Homo sapiens
291 UFL1 23376
Affinity Capture-MS Homo sapiens
292 RPL39 6170
Co-fractionation Homo sapiens
293 NEIL1  
Affinity Capture-MS Homo sapiens
294 CHMP4C 92421
Affinity Capture-MS Homo sapiens
295 RPS24 6229
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
296 NCL 4691
Affinity Capture-MS Homo sapiens
297 SEC61B 10952
Affinity Capture-MS Homo sapiens
298 RPL27A 6157
Co-fractionation Homo sapiens
299 PSMD9 5715
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
300 C16orf72 29035
Affinity Capture-MS Homo sapiens
301 ATG4B 23192
Affinity Capture-MS Homo sapiens
302 RPL7A 6130
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
303 TRAK1 22906
Cross-Linking-MS (XL-MS) Homo sapiens
304 RPS15 6209
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
305 RBM8A 9939
Affinity Capture-MS Homo sapiens
306 Rrbp1  
Affinity Capture-MS Mus musculus
307 RPL8 6132
Co-fractionation Homo sapiens
308 RPL27 6155
Co-fractionation Homo sapiens
309 L3MBTL1  
Affinity Capture-MS Homo sapiens
310 RPL28 6158
Co-fractionation Homo sapiens
311 SERBP1 26135
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
312 GLI4  
Affinity Capture-MS Homo sapiens
313 STT3B 201595
Co-fractionation Homo sapiens
314 RPL23A 6147
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
315 KRAS 3845
Negative Genetic Homo sapiens
316 HNRNPU 3192
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
317 GNB2L1 10399
Affinity Capture-MS Homo sapiens
318 RPS7 6201
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
319 RPL36AL 6166
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
320 RC3H1 149041
Affinity Capture-MS Homo sapiens
321 DDX3X 1654
Co-fractionation Homo sapiens
322 SSRP1 6749
Cross-Linking-MS (XL-MS) Homo sapiens
323 SRSF7 6432
Affinity Capture-MS Homo sapiens
324 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
325 MESDC2 23184
Cross-Linking-MS (XL-MS) Homo sapiens
326 RPL17 6139
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
327 EIF5 1983
Affinity Capture-MS Homo sapiens
328 CASQ2 845
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
329 C9orf72  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which RPS15 is involved
PathwayEvidenceSource
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S TAS Reactome
Axon guidance IEA Reactome
Cap-dependent Translation Initiation TAS Reactome
Cellular response to starvation IEA Reactome
Cellular responses to stimuli IEA Reactome
Cellular responses to stress IEA Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Eukaryotic Translation Elongation IEA Reactome
Eukaryotic Translation Initiation TAS Reactome
Eukaryotic Translation Termination IEA Reactome
Formation of a pool of free 40S subunits TAS Reactome
Formation of the ternary complex, and subsequently, the 43S complex TAS Reactome
GTP hydrolysis and joining of the 60S ribosomal subunit TAS Reactome
Infectious disease TAS Reactome
Influenza Infection TAS Reactome
Influenza Viral RNA Transcription and Replication TAS Reactome
L13a-mediated translational silencing of Ceruloplasmin expression TAS Reactome
Major pathway of rRNA processing in the nucleolus and cytosol TAS Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome
Metabolism of proteins TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of RNA TAS Reactome
Nervous system development IEA Reactome
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) TAS Reactome
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) TAS Reactome
Nonsense-Mediated Decay (NMD) TAS Reactome
Peptide chain elongation IEA Reactome
Regulation of expression of SLITs and ROBOs IEA Reactome
Response of EIF2AK4 (GCN2) to amino acid deficiency IEA Reactome
Ribosomal scanning and start codon recognition TAS Reactome
rRNA processing TAS Reactome
rRNA processing in the nucleus and cytosol TAS Reactome
SARS-CoV Infections TAS Reactome
SARS-CoV-1 Infection TAS Reactome
SARS-CoV-1 modulates host translation machinery TAS Reactome
SARS-CoV-1-host interactions TAS Reactome
SARS-CoV-2 Infection TAS Reactome
SARS-CoV-2 modulates host translation machinery TAS Reactome
SARS-CoV-2-host interactions TAS Reactome
Selenoamino acid metabolism IEA Reactome
Selenocysteine synthesis IEA Reactome
Signaling by ROBO receptors IEA Reactome
SRP-dependent cotranslational protein targeting to membrane IEA Reactome
SRP-dependent cotranslational protein targeting to membrane TAS Reactome
Translation TAS Reactome
Translation IEA Reactome
Translation initiation complex formation TAS Reactome
Viral Infection Pathways TAS Reactome
Viral mRNA Translation TAS Reactome





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