Experiment description of studies that identified C7orf50 in exosomes

1 Experiment ID 207 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|HSP70|FLOT1 Enriched markers ✔ VDAC Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name DKO-1 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

2 Experiment ID 208 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|HSP70|FLOT1 Enriched markers ✔ VDAC Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name Dks-8 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 209 MISEV standards ✘ Biophysical techniques ✔ TSG101|HSP70|FLOT1 Enriched markers ✔ VDAC Negative markers ✔ NTA Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23161513     Organism Homo sapiens Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Authors Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ. Journal name Mol Cell Proteomics Publication year 2012 Sample Colorectal cancer cells Sample name DLD-1 Isolation/purification methods Differential centrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

Protein-protein interactions for C7orf50

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HNRNPH1 3187 Affinity Capture-RNA Homo sapiens 2 ZNF668   Affinity Capture-MS Homo sapiens 3 UBE2H 7328 Affinity Capture-MS Homo sapiens 4 KIF23 9493 Affinity Capture-MS Homo sapiens 5 PAXIP1   Affinity Capture-MS Homo sapiens 6 ZNF346   Affinity Capture-MS Homo sapiens 7 RPL30 6156 Affinity Capture-MS Homo sapiens 8 RPA2 6118 Affinity Capture-MS Homo sapiens 9 RPL13A 23521 Affinity Capture-MS Homo sapiens 10 FBXO25   Biochemical Activity Homo sapiens 11 NOP56 10528 Affinity Capture-MS Homo sapiens 12 RPL10 6134 Affinity Capture-MS Homo sapiens 13 RPL14 9045 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 CAND1 55832 Affinity Capture-MS Homo sapiens 15 CCDC124 115098 Affinity Capture-MS Homo sapiens 16 SOX2   Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 17 APP 351 Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 18 USP36   Affinity Capture-MS Homo sapiens 19 TOP2A 7153 Affinity Capture-MS Homo sapiens 20 ETV3   Proximity Label-MS Homo sapiens 21 PRR11   Affinity Capture-MS Homo sapiens 22 PCNT   Affinity Capture-MS Homo sapiens 23 Nedd4 25489 Reconstituted Complex Rattus norvegicus 24 COPS5 10987 Affinity Capture-MS Homo sapiens 25 FBXW7   Affinity Capture-MS Homo sapiens 26 NPM1 4869 Affinity Capture-MS Homo sapiens 27 ETV4   Proximity Label-MS Homo sapiens 28 KLF6   Proximity Label-MS Homo sapiens 29 KLF15   Proximity Label-MS Homo sapiens 30 ADARB1 104 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 31 PRKRA 8575 Affinity Capture-MS Homo sapiens 32 PSMB6 5694 Co-fractionation Homo sapiens 33 LHX4   Proximity Label-MS Homo sapiens 34 CUL1 8454 Affinity Capture-MS Homo sapiens 35 MYCN   Affinity Capture-MS Homo sapiens 36 RPL19 6143 Affinity Capture-MS Homo sapiens 37 ESR1   Affinity Capture-MS Homo sapiens 38 PRNP 5621 Reconstituted Complex Homo sapiens 39 LIN28A   Affinity Capture-MS Homo sapiens 40 KLF16   Proximity Label-MS Homo sapiens 41 CHMP4C 92421 Affinity Capture-MS Homo sapiens 42 SRP9 6726 Affinity Capture-MS Homo sapiens 43 KLF9 687 Proximity Label-MS Homo sapiens 44 FOXA1   Affinity Capture-MS Homo sapiens 45 HIST1H4A 8359 Affinity Capture-MS Homo sapiens 46 SOX17   Proximity Label-MS Homo sapiens 47 RPL4 6124 Affinity Capture-MS Homo sapiens 48 ZBTB47   Affinity Capture-MS Homo sapiens 49 RRP9 9136 Affinity Capture-MS Homo sapiens 50 RBM4B   Affinity Capture-MS Homo sapiens 51 MAPRE1 22919 Affinity Capture-MS Homo sapiens 52 SRSF6 6431 Affinity Capture-MS Homo sapiens 53 PURG   Affinity Capture-MS Homo sapiens 54 RPL5 6125 Affinity Capture-MS Homo sapiens 55 RPL18A 6142 Affinity Capture-MS Homo sapiens 56 LHX1   Proximity Label-MS Homo sapiens 57 LHX2   Proximity Label-MS Homo sapiens 58 NTRK1 4914 Affinity Capture-MS Homo sapiens 59 IFI16 3428 Affinity Capture-MS Homo sapiens 60 HIST1H1E 3008 Affinity Capture-MS Homo sapiens 61 REXO4   Affinity Capture-MS Homo sapiens 62 CBX6   Affinity Capture-MS Homo sapiens 63 RPL37A 6168 Affinity Capture-MS Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens 64 LYAR 55646 Affinity Capture-MS Homo sapiens 65 HECTD1 25831 Affinity Capture-MS Homo sapiens 66 RPLP0 6175 Affinity Capture-MS Homo sapiens 67 MAGEB2 4113 Affinity Capture-MS Homo sapiens 68 MYBBP1A 10514 Affinity Capture-MS Homo sapiens 69 KLF12   Proximity Label-MS Homo sapiens 70 Ksr1   Affinity Capture-MS Mus musculus 71 SEC61B 10952 Affinity Capture-MS Homo sapiens 72 CYLD   Affinity Capture-MS Homo sapiens 73 SP100 6672 Affinity Capture-MS Homo sapiens 74 RPL11 6135 Affinity Capture-MS Homo sapiens 75 CNBP 7555 Affinity Capture-MS Homo sapiens 76 ANLN 54443 Affinity Capture-MS Homo sapiens 77 FGFBP1 9982 Affinity Capture-MS Homo sapiens 78 TLX2   Proximity Label-MS Homo sapiens 79 RPL32 6161 Affinity Capture-MS Homo sapiens 80 ZBTB2 57621 Affinity Capture-MS Homo sapiens 81 ABT1 29777 Affinity Capture-MS Homo sapiens 82 ECT2 1894 Affinity Capture-MS Homo sapiens 83 RPL35 11224 Affinity Capture-MS Homo sapiens 84 SRSF1 6426 Affinity Capture-MS Homo sapiens 85 LHX3   Proximity Label-MS Homo sapiens 86 NPM3 10360 Affinity Capture-MS Homo sapiens 87 RPS6 6194 Affinity Capture-MS Homo sapiens 88 RPL3 6122 Affinity Capture-MS Homo sapiens 89 YY1 7528 Proximity Label-MS Homo sapiens 90 ZC3H10   Affinity Capture-MS Homo sapiens 91 THAP1   Two-hybrid Homo sapiens Two-hybrid Homo sapiens 92 SOX15   Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 93 GRSF1 2926 Proximity Label-MS Homo sapiens 94 RPL36 25873 Affinity Capture-MS Homo sapiens 95 MYC   Affinity Capture-MS Homo sapiens 96 RPA3 6119 Affinity Capture-MS Homo sapiens 97 CCDC85B   Two-hybrid Homo sapiens 98 HIST1H1A 3024 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 99 DDRGK1 65992 Affinity Capture-MS Homo sapiens 100 RNF2   Affinity Capture-MS Homo sapiens 101 ZC3HAV1 56829 Affinity Capture-MS Homo sapiens 102 CCDC140   Affinity Capture-MS Homo sapiens 103 ZC3H3   Affinity Capture-MS Homo sapiens 104 NEDD4L 23327 Reconstituted Complex Homo sapiens 105 HUWE1 10075 Affinity Capture-MS Homo sapiens 106 RPL13 6137 Affinity Capture-MS Homo sapiens 107 SURF6   Affinity Capture-MS Homo sapiens 108 RNF151   Affinity Capture-MS Homo sapiens 109 HDGF 3068 Affinity Capture-MS Homo sapiens 110 MNDA 4332 Affinity Capture-MS Homo sapiens 111 STRN4 29888 Cross-Linking-MS (XL-MS) Homo sapiens 112 RPA1 6117 Affinity Capture-MS Homo sapiens 113 DGCR8   Affinity Capture-MS Homo sapiens 114 RPS15 6209 Affinity Capture-MS Homo sapiens 115 G3BP2 9908 Affinity Capture-MS Homo sapiens 116 PAX9   Proximity Label-MS Homo sapiens 117 MKI67   Affinity Capture-MS Homo sapiens 118 KLF8   Proximity Label-MS Homo sapiens 119 THAP7   Affinity Capture-MS Homo sapiens 120 NEIL1   Affinity Capture-MS Homo sapiens 121 RPL38 6169 Affinity Capture-MS Homo sapiens 122 NCL 4691 Affinity Capture-MS Homo sapiens 123 Rprd1b   Affinity Capture-MS Mus musculus 124 IL17B 27190 Affinity Capture-MS Homo sapiens 125 RPL7A 6130 Affinity Capture-MS Homo sapiens 126 RPS8 6202 Affinity Capture-MS Homo sapiens 127 RPL8 6132 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 128 RPL28 6158 Affinity Capture-MS Homo sapiens 129 SP7   Proximity Label-MS Homo sapiens 130 RPL17 6139 Affinity Capture-MS Homo sapiens 131 NHLH1   Proximity Label-MS Homo sapiens View the network

Pathways in which C7orf50 is involved

No pathways found