Gene description for KLF9
Gene name Kruppel-like factor 9
Gene symbol KLF9
Other names/aliases BTEB
BTEB1
Species Homo sapiens
 Database cross references - KLF9
ExoCarta ExoCarta_687
Entrez Gene 687
HGNC 1123
MIM 602902
UniProt Q13886  
 KLF9 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for KLF9
Molecular Function
    DNA binding GO:0003677 IEA
    sequence-specific DNA binding transcription factor activity GO:0003700 TAS
    metal ion binding GO:0046872 IEA
Biological Process
    regulation of transcription from RNA polymerase II promoter GO:0006357 TAS
    embryo implantation GO:0007566 IEA
    transcription, DNA-templated GO:0006351 IEA
    progesterone receptor signaling pathway GO:0050847 IEA
    cellular response to cortisol stimulus GO:0071387 IDA
    negative regulation of keratinocyte proliferation GO:0010839 IMP
    circadian rhythm GO:0007623 IEP
    cellular response to thyroid hormone stimulus GO:0097067 IDA
Subcellular Localization
    plasma membrane GO:0005886 IDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified KLF9 in exosomes
1
Experiment ID 226
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD9|FLOT1
EV Membrane markers
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for KLF9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SIN3A  
Reconstituted Complex Homo sapiens
2 PGR  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which KLF9 is involved
No pathways found





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