Gene description for KLF9
Gene name Kruppel-like factor 9
Gene symbol KLF9
Other names/aliases BTEB
BTEB1
Species Homo sapiens
 Database cross references - KLF9
ExoCarta ExoCarta_687
Vesiclepedia VP_687
Entrez Gene 687
HGNC 1123
MIM 602902
UniProt Q13886  
 KLF9 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for KLF9
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 ISA
    DNA-binding transcription factor activity GO:0003700 TAS
    metal ion binding GO:0046872 IEA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
    circadian rhythm GO:0007623 IEP
    negative regulation of keratinocyte proliferation GO:0010839 IMP
    cellular response to cortisol stimulus GO:0071387 IDA
Subcellular Localization
    chromatin GO:0000785 ISA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    cytosol GO:0005829 IDA
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified KLF9 in exosomes
1
Experiment ID 226
MISEV standards
EM
Biophysical techniques
GAPDH|CD9|FLOT1
Enriched markers
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for KLF9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
2 CDCA2 157313
Proximity Label-MS Homo sapiens
3 RPL26L1 51121
Proximity Label-MS Homo sapiens
4 SP1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
5 MNT  
Proximity Label-MS Homo sapiens
6 PGR  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
7 GPATCH4 54865
Proximity Label-MS Homo sapiens
8 C11orf30  
Proximity Label-MS Homo sapiens
9 DDX24 57062
Proximity Label-MS Homo sapiens
10 SMARCA1 6594
Proximity Label-MS Homo sapiens
11 NR2C2  
Proximity Label-MS Homo sapiens
12 E2F6 1876
Proximity Label-MS Homo sapiens
13 ZNF148  
Proximity Label-MS Homo sapiens
14 ARID4B  
Proximity Label-MS Homo sapiens
15 ATAD5  
Proximity Label-MS Homo sapiens
16 KRI1  
Proximity Label-MS Homo sapiens
17 ZNF644  
Proximity Label-MS Homo sapiens
18 NUSAP1 51203
Proximity Label-MS Homo sapiens
19 DDX18 8886
Proximity Label-MS Homo sapiens
20 ZBTB14  
Proximity Label-MS Homo sapiens
21 CTCF  
Proximity Label-MS Homo sapiens
22 PPP1CA 5499
Affinity Capture-MS Homo sapiens
23 CPVL 54504
Affinity Capture-MS Homo sapiens
24 RLF 6018
Proximity Label-MS Homo sapiens
25 RBM28 55131
Proximity Label-MS Homo sapiens
26 BRMS1 25855
Proximity Label-MS Homo sapiens
27 HIVEP1 3096
Proximity Label-MS Homo sapiens
28 BLM 641
Proximity Label-MS Homo sapiens
29 FAM60A  
Proximity Label-MS Homo sapiens
30 ACACA 31
Positive Genetic Homo sapiens
31 DDX10  
Proximity Label-MS Homo sapiens
32 ANKHD1 54882
Affinity Capture-MS Homo sapiens
33 ZKSCAN4  
Proximity Label-MS Homo sapiens
34 ZNF131  
Proximity Label-MS Homo sapiens
35 SUDS3  
Proximity Label-MS Homo sapiens
36 MRPL11 65003
Proximity Label-MS Homo sapiens
37 PHF12  
Proximity Label-MS Homo sapiens
38 DDX27 55661
Proximity Label-MS Homo sapiens
39 GTPBP4 23560
Proximity Label-MS Homo sapiens
40 GLTSCR2  
Proximity Label-MS Homo sapiens
41 ARID4A  
Proximity Label-MS Homo sapiens
42 ING2  
Proximity Label-MS Homo sapiens
43 CNBP 7555
Affinity Capture-MS Homo sapiens
44 BRD7  
Proximity Label-MS Homo sapiens
45 ECH1 1891
Proximity Label-MS Homo sapiens
46 BMS1  
Proximity Label-MS Homo sapiens
47 MRTO4 51154
Proximity Label-MS Homo sapiens
48 BAZ1B 9031
Proximity Label-MS Homo sapiens
49 EIF6 3692
Proximity Label-MS Homo sapiens
50 MGA  
Proximity Label-MS Homo sapiens
51 ERBB2IP 55914
Affinity Capture-MS Homo sapiens
52 RPL36A 6173
Proximity Label-MS Homo sapiens
53 EBNA1BP2 10969
Proximity Label-MS Homo sapiens
54 YY1 7528
Proximity Label-MS Homo sapiens
55 BBX 56987
Proximity Label-MS Homo sapiens
56 SORD 6652
Affinity Capture-MS Homo sapiens
57 SIN3B  
Proximity Label-MS Homo sapiens
58 STRAP 11171
Affinity Capture-MS Homo sapiens
59 ZNF512  
Proximity Label-MS Homo sapiens
60 SS18L2  
Proximity Label-MS Homo sapiens
61 SEC16A 9919
Proximity Label-MS Homo sapiens
62 INO80  
Proximity Label-MS Homo sapiens
63 EHMT2 10919
Proximity Label-MS Homo sapiens
64 NOP16 51491
Proximity Label-MS Homo sapiens
65 PDCD11 22984
Proximity Label-MS Homo sapiens
66 FOXK1 221937
Proximity Label-MS Homo sapiens
67 FTSJ3 117246
Proximity Label-MS Homo sapiens
68 BRMS1L  
Proximity Label-MS Homo sapiens
69 TPM3 7170
Affinity Capture-MS Homo sapiens
70 ARID2  
Proximity Label-MS Homo sapiens
71 SAP130  
Proximity Label-MS Homo sapiens
72 MAX  
Proximity Label-MS Homo sapiens
73 SIN3A  
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
74 NPAT  
Proximity Label-MS Homo sapiens
75 PBRM1 55193
Proximity Label-MS Homo sapiens
76 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
77 GON4L  
Proximity Label-MS Homo sapiens
78 ATP2A2 488
Proximity Label-MS Homo sapiens
79 RPL34 6164
Proximity Label-MS Homo sapiens
80 PWP1 11137
Proximity Label-MS Homo sapiens
81 ING1  
Proximity Label-MS Homo sapiens
82 NR2C1  
Proximity Label-MS Homo sapiens
83 PHF23 79142
Proximity Label-MS Homo sapiens
84 GATAD1  
Proximity Label-MS Homo sapiens
85 RBM34  
Proximity Label-MS Homo sapiens
86 GABPA 2551
Proximity Label-MS Homo sapiens
87 PHF8  
Proximity Label-MS Homo sapiens
88 C7orf50 84310
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which KLF9 is involved
No pathways found





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