Experiment description of studies that identified DDX24 in sEVs

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for DDX24

Protein Interactor ExoCarta ID Identification method PubMed Species 1 RPL11 6135 Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens 2 ZBTB38 253461 Affinity Capture-MS Homo sapiens 3 ZNF668   Affinity Capture-MS Homo sapiens 4 RPF2 84154 Co-fractionation Homo sapiens 5 KLF6   Proximity Label-MS Homo sapiens 6 TRDMT1   Two-hybrid Homo sapiens 7 RPL26L1 51121 Affinity Capture-MS Homo sapiens 8 Mdm2   Affinity Capture-Western Mus musculus Affinity Capture-MS Mus musculus Affinity Capture-Western Mus musculus 9 Eif4a2 13682 Two-hybrid Mus musculus 10 SPRTN   Affinity Capture-MS Homo sapiens 11 NOP58 51602 Co-fractionation Homo sapiens 12 DNAJC9 23234 Proximity Label-MS Homo sapiens 13 CNBP 7555 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 COIL   Proximity Label-MS Homo sapiens 15 ZNF346   Affinity Capture-MS Homo sapiens 16 NPM3 10360 Affinity Capture-MS Homo sapiens 17 KIAA0020 9933 Co-fractionation Homo sapiens 18 SRPK2 6733 Affinity Capture-MS Homo sapiens 19 DDX21 9188 Affinity Capture-MS Homo sapiens 20 LHX2   Proximity Label-MS Homo sapiens 21 RPL13A 23521 Affinity Capture-MS Homo sapiens 22 RPL37A 6168 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 23 LIN28B   Affinity Capture-MS Homo sapiens 24 BRCA1 672 Two-hybrid Homo sapiens 25 RPL23AP32 56969 Affinity Capture-MS Homo sapiens 26 RPL10 6134 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 27 RPL15 6138 Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens 28 BRD2   Affinity Capture-MS Homo sapiens 29 RPL14 9045 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 30 CSNK2A1 1457 Biochemical Activity Homo sapiens Affinity Capture-MS Homo sapiens 31 PNMAL1   Affinity Capture-MS Homo sapiens 32 CAND1 55832 Affinity Capture-MS Homo sapiens 33 LOC100132735   Protein-RNA Homo sapiens 34 INTS6 26512 Co-fractionation Homo sapiens 35 SOX2   Proximity Label-MS Homo sapiens 36 CENPA   Proximity Label-MS Homo sapiens 37 USP36   Affinity Capture-MS Homo sapiens 38 EGFR 1956 Negative Genetic Homo sapiens 39 DDX23 9416 Proximity Label-MS Homo sapiens 40 GPATCH4 54865 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 41 RPS2 6187 Affinity Capture-MS Homo sapiens 42 SART3 9733 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 43 PRR11   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 44 NSA2   Co-fractionation Homo sapiens 45 RPL28 6158 Affinity Capture-MS Homo sapiens 46 OTUB1 55611 Affinity Capture-MS Homo sapiens 47 USP39 10713 Affinity Capture-MS Homo sapiens 48 H2AFB3   Affinity Capture-MS Homo sapiens 49 RPA3 6119 Proximity Label-MS Homo sapiens 50 RRP12 23223 Co-fractionation Homo sapiens 51 ZBTB47   Affinity Capture-MS Homo sapiens 52 NPM1 4869 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 53 ANOS1 3730 Affinity Capture-MS Homo sapiens 54 POU5F1   Affinity Capture-MS Homo sapiens 55 BRPF3   Affinity Capture-MS Homo sapiens 56 H2AFY2 55506 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 57 FGF17   Affinity Capture-MS Homo sapiens 58 ZNF2   Affinity Capture-MS Homo sapiens 59 Set 56086 Affinity Capture-MS Mus musculus 60 ADARB1 104 Affinity Capture-MS Homo sapiens 61 EIF3E 3646 Two-hybrid Homo sapiens 62 PRKRA 8575 Affinity Capture-MS Homo sapiens 63 GRWD1 83743 Co-fractionation Homo sapiens 64 XRN1 54464 Co-fractionation Homo sapiens 65 ZC3HAV1 56829 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 66 SLC25A46 91137 Proximity Label-MS Homo sapiens 67 ABT1 29777 Affinity Capture-MS Homo sapiens 68 DDX18 8886 Co-fractionation Homo sapiens 69 RRP8   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 70 FBL 2091 Co-fractionation Homo sapiens 71 MECP2 4204 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 72 TLX3   Proximity Label-MS Homo sapiens 73 MYCN   Affinity Capture-MS Homo sapiens 74 WDR12 55759 Co-fractionation Homo sapiens 75 OASL 8638 Affinity Capture-MS Homo sapiens 76 USP7 7874 Affinity Capture-MS Homo sapiens 77 CSNK2B 1460 Affinity Capture-MS Homo sapiens 78 MAK16   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 79 PSMD14 10213 Affinity Capture-MS Homo sapiens 80 RPL19 6143 Affinity Capture-MS Homo sapiens 81 RBPJ 3516 Affinity Capture-MS Homo sapiens 82 KIF14 9928 Affinity Capture-MS Homo sapiens 83 PES1 23481 Co-fractionation Homo sapiens 84 LIN28A   Affinity Capture-MS Homo sapiens 85 NAP1L2   Affinity Capture-MS Homo sapiens 86 POLA2   Two-hybrid Homo sapiens 87 KLF16   Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 88 TBL3 10607 Co-fractionation Homo sapiens 89 KLF5   Proximity Label-MS Homo sapiens 90 DDX31   Co-fractionation Homo sapiens 91 RPL30 6156 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 92 NOP2 4839 Co-fractionation Homo sapiens 93 HIST1H4A 8359 Affinity Capture-MS Homo sapiens 94 CNOT2   Affinity Capture-MS Homo sapiens 95 FASTKD5   Proximity Label-MS Homo sapiens 96 EMD 2010 Proximity Label-MS Homo sapiens 97 SRP14 6727 Affinity Capture-MS Homo sapiens 98 RPL4 6124 Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens 99 RBM28 55131 Affinity Capture-MS Homo sapiens 100 NOL6 65083 Co-fractionation Homo sapiens 101 RBM19 9904 Affinity Capture-MS Homo sapiens 102 CLSTN1 22883 Affinity Capture-MS Homo sapiens 103 HIST1H2AG 8969 Cross-Linking-MS (XL-MS) Homo sapiens 104 ERGIC2 51290 Proximity Label-MS Homo sapiens 105 RBM4B   Affinity Capture-MS Homo sapiens 106 YBX2 51087 Affinity Capture-MS Homo sapiens 107 RPL5 6125 Co-fractionation Homo sapiens 108 SRSF6 6431 Affinity Capture-MS Homo sapiens 109 PURG   Affinity Capture-MS Homo sapiens 110 ZBTB48   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 111 UBE2I 7329 Biochemical Activity Homo sapiens 112 HIST1H2AM 8336 Affinity Capture-MS Homo sapiens 113 RPL18A 6142 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 114 LHX1   Proximity Label-MS Homo sapiens 115 Srp72   Affinity Capture-MS Mus musculus 116 GIT1 28964 Two-hybrid Homo sapiens 117 RPS25 6230 Co-fractionation Homo sapiens 118 TSPYL2   Affinity Capture-MS Homo sapiens 119 RPS10 6204 Affinity Capture-MS Homo sapiens 120 NTRK1 4914 Affinity Capture-MS Homo sapiens 121 FGF8   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 122 RSL1D1 26156 Affinity Capture-MS Homo sapiens 123 KMT2E   Affinity Capture-MS Homo sapiens 124 HIST1H1E 3008 Affinity Capture-MS Homo sapiens 125 REXO4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 126 SYNCRIP 10492 Affinity Capture-MS Homo sapiens 127 NCL 4691 Affinity Capture-Western Homo sapiens 128 RPL36 25873 Affinity Capture-MS Homo sapiens 129 HIST1H1C 3006 Affinity Capture-MS Homo sapiens 130 RPL27A 6157 Affinity Capture-MS Homo sapiens 131 ZCCHC10   Affinity Capture-MS Homo sapiens 132 LYAR 55646 Affinity Capture-MS Homo sapiens 133 HECTD1 25831 Affinity Capture-MS Homo sapiens 134 RPLP0 6175 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens 135 SRPK3   Affinity Capture-MS Homo sapiens 136 MAGEB2 4113 Affinity Capture-MS Homo sapiens 137 MYBBP1A 10514 Affinity Capture-MS Homo sapiens 138 KLF12   Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 139 GTPBP4 23560 Co-fractionation Homo sapiens 140 SOX17   Proximity Label-MS Homo sapiens 141 TSR2   Co-fractionation Homo sapiens 142 NOP56 10528 Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens Co-fractionation Homo sapiens 143 MGMT 4255 Affinity Capture-MS Homo sapiens 144 CD3EAP   Proximity Label-MS Homo sapiens 145 WDR46   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 146 SCARNA22   Affinity Capture-RNA Homo sapiens 147 FGFBP1 9982 Affinity Capture-MS Homo sapiens 148 TLX2   Proximity Label-MS Homo sapiens 149 RPL23A 6147 Affinity Capture-MS Homo sapiens 150 HSPA5 3309 Two-hybrid Homo sapiens 151 ZBTB2 57621 Affinity Capture-MS Homo sapiens 152 HMGN4   Affinity Capture-MS Homo sapiens 153 RPS19 6223 Affinity Capture-MS Homo sapiens 154 RPL10A 4736 Affinity Capture-MS Homo sapiens 155 RPL31 6160 Proximity Label-MS Homo sapiens 156 RPLP2 6181 Co-fractionation Homo sapiens 157 UBE2H 7328 Affinity Capture-MS Homo sapiens 158 NOC3L 64318 Co-fractionation Homo sapiens 159 TPI1 7167 Two-hybrid Homo sapiens 160 RPL7A 6130 Affinity Capture-MS Homo sapiens 161 MRTO4 51154 Co-fractionation Homo sapiens 162 RPL13 6137 Affinity Capture-MS Homo sapiens 163 C9orf78 51759 Affinity Capture-MS Homo sapiens 164 RC3H2   Affinity Capture-MS Homo sapiens 165 RBBP6 5930 Co-fractionation Homo sapiens 166 SIRT7   Affinity Capture-MS Homo sapiens 167 SRSF4 6429 Affinity Capture-MS Homo sapiens 168 IFI16 3428 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 169 SRSF1 6426 Affinity Capture-MS Homo sapiens 170 BRD8 10902 Affinity Capture-MS Homo sapiens 171 IFT57 55081 Affinity Capture-MS Homo sapiens 172 HSP90AB1 3326 Two-hybrid Homo sapiens 173 CUL3 8452 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 174 RPS6 6194 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 175 GLRA2   Two-hybrid Homo sapiens 176 SRSF5 6430 Affinity Capture-MS Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens 177 RPL3 6122 Affinity Capture-MS Homo sapiens 178 EBNA1BP2 10969 Co-fractionation Homo sapiens 179 THOC5 8563 Affinity Capture-MS Homo sapiens 180 ARF6 382 Proximity Label-MS Homo sapiens 181 RPL35 11224 Affinity Capture-MS Homo sapiens 182 RPL7 6129 Co-fractionation Homo sapiens 183 NIP7 51388 Co-fractionation Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 184 HNRNPCL2 440563 Affinity Capture-MS Homo sapiens 185 OCIAD1 54940 Proximity Label-MS Homo sapiens 186 NXF1 10482 Affinity Capture-RNA Homo sapiens 187 SPTAN1 6709 Two-hybrid Homo sapiens 188 TERF2IP 54386 Two-hybrid Homo sapiens 189 ZNF512   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 190 SGTB   Affinity Capture-MS Homo sapiens 191 CEP250 11190 Affinity Capture-MS Homo sapiens 192 MAP2K3 5606 Affinity Capture-MS Homo sapiens 193 CBX6   Affinity Capture-MS Homo sapiens 194 PCBP1 5093 Affinity Capture-MS Homo sapiens 195 TRIM44   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 196 DKC1 1736 Co-fractionation Homo sapiens 197 MYC   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 198 HECW2   Affinity Capture-MS Homo sapiens 199 ATP2A1 487 Proximity Label-MS Homo sapiens 200 THAP3   Affinity Capture-MS Homo sapiens 201 ZNF692   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 202 ZMYND8 23613 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 203 NOL12 79159 Affinity Capture-MS Homo sapiens 204 CSNK2A2 1459 Affinity Capture-MS Homo sapiens 205 RPS14 6208 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 206 INO80   Co-fractionation Homo sapiens 207 NHP2L1 4809 Co-fractionation Homo sapiens 208 KLF15   Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 209 RPL22 6146 Affinity Capture-MS Homo sapiens 210 ZNF687   Affinity Capture-MS Homo sapiens 211 HIST1H1A 3024 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 212 CORO1A 11151 Affinity Capture-MS Homo sapiens 213 SET 6418 Affinity Capture-MS Homo sapiens 214 RPL18 6141 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 215 DDRGK1 65992 Affinity Capture-MS Homo sapiens 216 RNF2   Affinity Capture-MS Homo sapiens 217 RHOB 388 Proximity Label-MS Homo sapiens 218 FOXQ1   Affinity Capture-MS Homo sapiens 219 H2AFB2   Affinity Capture-MS Homo sapiens 220 NANOG   Affinity Capture-MS Homo sapiens 221 ZC3H3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 222 FTSJ3 117246 Co-fractionation Homo sapiens 223 MDM2   Reconstituted Complex Homo sapiens Biochemical Activity Homo sapiens Affinity Capture-Western Homo sapiens 224 GNL3 26354 Co-fractionation Homo sapiens 225 DDX55   Co-fractionation Homo sapiens 226 ITGB3BP   Two-hybrid Homo sapiens 227 ETV3   Proximity Label-MS Homo sapiens 228 SDC2 6383 Affinity Capture-MS Homo sapiens 229 Cbx1   Affinity Capture-MS Mus musculus 230 SURF6   Affinity Capture-MS Homo sapiens 231 VDAC3 7419 Two-hybrid Homo sapiens 232 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 233 MKRN1 23608 Affinity Capture-MS Homo sapiens 234 ZC3H10   Affinity Capture-MS Homo sapiens 235 TERF2   Two-hybrid Homo sapiens 236 AUH 549 Proximity Label-MS Homo sapiens 237 LAMTOR1 55004 Proximity Label-MS Homo sapiens 238 PDZD2   Affinity Capture-Western Homo sapiens 239 SPANXN2   Affinity Capture-MS Homo sapiens 240 PAFAH1B3 5050 Two-hybrid Homo sapiens 241 FBXL6   Affinity Capture-MS Homo sapiens 242 TP53 7157 Affinity Capture-MS Homo sapiens 243 RPL6 6128 Co-fractionation Homo sapiens 244 MKS1 54903 Two-hybrid Homo sapiens 245 POTEJ 653781 Co-fractionation Homo sapiens 246 TSPYL6   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 247 SOX15   Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 248 MNDA 4332 Affinity Capture-MS Homo sapiens 249 PIN1 5300 Two-hybrid Homo sapiens 250 GRSF1 2926 Proximity Label-MS Homo sapiens 251 RNF151   Affinity Capture-MS Homo sapiens 252 DGCR8   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 253 KNOP1 400506 Affinity Capture-MS Homo sapiens 254 RPS4X 6191 Co-fractionation Homo sapiens 255 ZNF48   Affinity Capture-MS Homo sapiens 256 PTBP3 9991 Affinity Capture-MS Homo sapiens 257 CHD4 1108 Affinity Capture-MS Homo sapiens 258 TSPYL1 7259 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 259 G3BP2 9908 Affinity Capture-MS Homo sapiens 260 SHMT2 6472 Affinity Capture-RNA Homo sapiens 261 MAGEA9   Affinity Capture-MS Homo sapiens 262 MKI67   Affinity Capture-MS Homo sapiens 263 NIFK 84365 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens 264 LARP7 51574 Affinity Capture-MS Homo sapiens 265 BRIX1 55299 Co-fractionation Homo sapiens 266 KLF8   Proximity Label-MS Homo sapiens 267 THAP7   Affinity Capture-MS Homo sapiens 268 DDX27 55661 Co-fractionation Homo sapiens 269 UFL1 23376 Affinity Capture-MS Homo sapiens 270 PWP1 11137 Co-fractionation Homo sapiens 271 KRR1 11103 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens 272 RBM4 5936 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 273 NEIL1   Affinity Capture-MS Homo sapiens 274 TERF1 7013 Two-hybrid Homo sapiens 275 NOC2L 26155 Co-fractionation Homo sapiens 276 RPS24 6229 Proximity Label-MS Homo sapiens 277 MOV10 4343 Affinity Capture-RNA Homo sapiens 278 KLF9 687 Proximity Label-MS Homo sapiens 279 IL17B 27190 Affinity Capture-MS Homo sapiens 280 POLR1C 9533 Co-fractionation Homo sapiens 281 PARK2   Affinity Capture-MS Homo sapiens 282 TRIP4 9325 Affinity Capture-MS Homo sapiens 283 BCS1L 617 Two-hybrid Homo sapiens 284 GLI4   Affinity Capture-MS Homo sapiens 285 APBA2 321 Affinity Capture-MS Homo sapiens 286 Rrbp1   Affinity Capture-MS Mus musculus 287 RPL8 6132 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 288 BCCIP 56647 Co-fractionation Homo sapiens 289 BRD1 23774 Affinity Capture-MS Homo sapiens 290 PPAN 56342 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 291 KRAS 3845 Affinity Capture-MS Homo sapiens 292 HNRNPU 3192 Affinity Capture-MS Homo sapiens 293 RPS7 6201 Co-fractionation Homo sapiens 294 RPL36AL 6166 Affinity Capture-MS Homo sapiens 295 RC3H1 149041 Affinity Capture-MS Homo sapiens 296 RMDN3 55177 Proximity Label-MS Homo sapiens 297 SP7   Proximity Label-MS Homo sapiens 298 ZNF467   Affinity Capture-MS Homo sapiens 299 DDX56   Co-fractionation Homo sapiens 300 RPL17 6139 Affinity Capture-MS Homo sapiens 301 EP300 2033 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 302 NHLH1   Proximity Label-MS Homo sapiens View the network

Pathways in which DDX24 is involved

No pathways found