Gene description for TERF2IP
Gene name	telomeric repeat binding factor 2, interacting protein
Gene symbol	TERF2IP
Other names/aliases	DRIP5 RAP1
Species	Homo sapiens
Database cross references - TERF2IP
ExoCarta	ExoCarta_54386
Vesiclepedia	VP_54386
Entrez Gene	54386
HGNC	19246
MIM	605061
UniProt	Q9NYB0
TERF2IP identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for TERF2IP

Molecular Function     protein binding GO:0005515 IPI     phosphatase binding GO:0019902 IPI     telomeric DNA binding GO:0042162 IDA     telomeric DNA binding GO:0042162 TAS     G-rich strand telomeric DNA binding GO:0098505 IDA Biological Process     telomere maintenance GO:0000723 IDA     negative regulation of protein phosphorylation GO:0001933 IMP     regulation of DNA-templated transcription GO:0006355 IMP     regulation of DNA-templated transcription GO:0006355 ISS     telomere maintenance via telomerase GO:0007004 TAS     regulation of double-strand break repair via homologous recombination GO:0010569 ISS     telomere maintenance via telomere lengthening GO:0010833 IBA     telomere maintenance via telomere lengthening GO:0010833 ISS     telomere capping GO:0016233 IDA     protection from non-homologous end joining at telomere GO:0031848 IMP     protection from non-homologous end joining at telomere GO:0031848 ISS     regulation of telomere maintenance GO:0032204 IMP     negative regulation of telomere maintenance GO:0032205 IDA     positive regulation of telomere maintenance GO:0032206 NAS     intracellular signal transduction GO:0035556 IMP     positive regulation of canonical NF-kappaB signal transduction GO:0043123 ISS     negative regulation of DNA recombination at telomere GO:0048239 ISS     positive regulation of NF-kappaB transcription factor activity GO:0051092 ISS     protein localization to chromosome, telomeric region GO:0070198 IMP     positive regulation of non-canonical NF-kappaB signal transduction GO:1901224 IMP Subcellular Localization     nuclear chromosome GO:0000228 TAS     chromosome, telomeric region GO:0000781 HDA     chromosome, telomeric region GO:0000781 IDA     chromosome, telomeric region GO:0000781 ISS     nuclear telomere cap complex GO:0000783 IDA     male germ cell nucleus GO:0001673 IEA     nucleus GO:0005634 IDA     nucleus GO:0005634 ISS     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 TAS     cytoplasm GO:0005737 IDA     cytoplasm GO:0005737 ISS     nuclear body GO:0016604 IDA     shelterin complex GO:0070187 IBA     shelterin complex GO:0070187 IDA     shelterin complex GO:0070187 IPI