Gene description for TERF2IP
Gene name	telomeric repeat binding factor 2, interacting protein
Gene symbol	TERF2IP
Other names/aliases	DRIP5 RAP1
Species	Homo sapiens
Database cross references - TERF2IP
ExoCarta	ExoCarta_54386
Entrez Gene	54386
HGNC	19246
MIM	605061
UniProt	Q9NYB0
TERF2IP identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for TERF2IP

Molecular Function     telomeric DNA binding GO:0042162 TAS     protein binding GO:0005515 IPI Biological Process     telomere maintenance via telomere lengthening GO:0010833 ISS     telomere maintenance via telomerase GO:0007004 TAS     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 ISS     positive regulation of NF-kappaB transcription factor activity GO:0051092 ISS     negative regulation of telomere maintenance GO:0032205 IMP     positive regulation of peptidyl-serine phosphorylation GO:0033138 IMP     protection from non-homologous end joining at telomere GO:0031848 ISS     protein localization to chromosome, telomeric region GO:0070198 IMP     regulation of transcription, DNA-templated GO:0006355 ISS     telomere maintenance GO:0000723 TAS     positive regulation of protein acetylation GO:1901985 IMP     negative regulation of DNA recombination at telomere GO:0048239 ISS     transcription, DNA-templated GO:0006351 IEA     regulation of double-strand break repair via homologous recombination GO:0010569 ISS Subcellular Localization     nucleus GO:0005634 ISS     nuclear chromosome GO:0000228 TAS     chromosome, telomeric region GO:0000781 ISS     nuclear chromosome, telomeric region GO:0000784 IDA     nucleoplasm GO:0005654 TAS     nuclear telomere cap complex GO:0000783 IDA     Mre11 complex GO:0030870 IDA     nuclear envelope GO:0005635 IEA     cytoplasm GO:0005737 ISS