Gene description for EXOSC5
Gene name	exosome component 5
Gene symbol	EXOSC5
Other names/aliases	RRP41B RRP46 Rrp46p hRrp46p p12B
Species	Homo sapiens
Database cross references - EXOSC5
ExoCarta	ExoCarta_56915
Entrez Gene	56915
HGNC	24662
MIM	606492
UniProt	Q9NQT4
EXOSC5 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for EXOSC5

Molecular Function     exoribonuclease activity GO:0004532 IDA     3'-5'-exoribonuclease activity GO:0000175 NAS     RNA binding GO:0003723 IEA     protein binding GO:0005515 IPI Biological Process     polyadenylation-dependent snoRNA 3'-end processing GO:0071051 IBA     U4 snRNA 3'-end processing GO:0034475 IBA     nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' GO:0034427 IBA     nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 TAS     rRNA 3'-end processing GO:0031125 IBA     exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay GO:0043928 TAS     defense response to virus GO:0051607 IMP     gene expression GO:0010467 TAS     rRNA processing GO:0006364 NAS     nuclear mRNA surveillance GO:0071028 IBA     rRNA catabolic process GO:0016075 IBA     DNA deamination GO:0045006 IDA     RNA phosphodiester bond hydrolysis, exonucleolytic GO:0090503 NAS Subcellular Localization     exosome (RNase complex) GO:0000178 IDA     cytoplasm GO:0005737 NAS     cytoplasmic exosome (RNase complex) GO:0000177 IBA     nucleolus GO:0005730 NAS     transcriptionally active chromatin GO:0035327 IMP     nucleus GO:0005634 IDA     cytosol GO:0005829 TAS     nuclear exosome (RNase complex) GO:0000176 IBA