Gene description for Nudt21
Gene name nudix (nucleoside diphosphate linked moiety X)-type motif 21
Gene symbol Nudt21
Other names/aliases 25kDa
3110048P04Rik
5730530J16Rik
AU014860
AW549947
Cpsf5
Species Mus musculus
 Database cross references - Nudt21
ExoCarta ExoCarta_68219
Entrez Gene 68219
UniProt Q9CQF3  
 Nudt21 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Nudt21
Molecular Function
    mRNA binding GO:0003729 ISO
    histone deacetylase binding GO:0042826 ISO
    poly(A) RNA binding GO:0044822 ISO
    hydrolase activity GO:0016787 IEA
    protein homodimerization activity GO:0042803 ISO
    RNA binding GO:0003723 ISO
    AU-rich element binding GO:0017091 ISO
Biological Process
    mRNA cleavage GO:0006379 ISO
    mRNA polyadenylation GO:0006378 ISO
    mRNA processing GO:0006397 ISO
    protein tetramerization GO:0051262 ISO
Subcellular Localization
    paraspeckles GO:0042382 ISO
    nucleus GO:0005634 ISO
    mRNA cleavage factor complex GO:0005849 ISO
    centrosome GO:0005813 ISO
 Experiment description of studies that identified Nudt21 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Nudt21
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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