Gene description for CPSF7
Gene name cleavage and polyadenylation specific factor 7, 59kDa
Gene symbol CPSF7
Other names/aliases CFIm59
Species Homo sapiens
 Database cross references - CPSF7
ExoCarta ExoCarta_79869
Vesiclepedia VP_79869
Entrez Gene 79869
HGNC 30098
UniProt Q8N684  
 CPSF7 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for CPSF7
Molecular Function
    RNA binding GO:0003723 HDA
    mRNA binding GO:0003729 IBA
    protein binding GO:0005515 IPI
Biological Process
    mRNA 3'-end processing GO:0031124 IDA
    protein tetramerization GO:0051262 IDA
    protein heterotetramerization GO:0051290 IDA
    mRNA alternative polyadenylation GO:0110104 IBA
    mRNA alternative polyadenylation GO:0110104 IMP
    co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway GO:0180010 IDA
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IDA
    mRNA cleavage and polyadenylation specificity factor complex GO:0005847 IBA
    mRNA cleavage and polyadenylation specificity factor complex GO:0005847 IDA
    mRNA cleavage factor complex GO:0005849 IDA
    mRNA cleavage factor complex GO:0005849 IPI
    membrane GO:0016020 HDA
 Experiment description of studies that identified CPSF7 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
20
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CPSF7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPSA 3921
Affinity Capture-MS Homo sapiens
2 FAM58A  
Affinity Capture-MS Homo sapiens
3 GATA1  
Proximity Label-MS Homo sapiens
4 Mrpl13  
Two-hybrid Mus musculus
5 PCED1A  
Affinity Capture-MS Homo sapiens
6 Larp7  
Two-hybrid Mus musculus
7 PQBP1  
Two-hybrid Homo sapiens
8 GLUD1 2746
Affinity Capture-MS Homo sapiens
9 DGCR14  
Two-hybrid Homo sapiens
10 EPM2AIP1 9852
Two-hybrid Homo sapiens
11 HOXA5  
Affinity Capture-MS Homo sapiens
12 RBPMS 11030
Two-hybrid Homo sapiens
13 PCF11 51585
Co-fractionation Homo sapiens
14 WWP1 11059
Affinity Capture-MS Homo sapiens
15 LENG8  
Two-hybrid Homo sapiens
16 ATXN2L 11273
Affinity Capture-MS Homo sapiens
17 SRPK2 6733
Two-hybrid Homo sapiens
18 AES 166
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
19 RCL1 10171
Affinity Capture-MS Homo sapiens
20 TPM2 7169
Co-fractionation Homo sapiens
21 RPA2 6118
Affinity Capture-MS Homo sapiens
22 PRPF38A 84950
Affinity Capture-MS Homo sapiens
23 QKI 9444
Two-hybrid Homo sapiens
24 ACTC1 70
Proximity Label-MS Homo sapiens
25 GAK 2580
Affinity Capture-MS Homo sapiens
26 TSG101 7251
Affinity Capture-MS Homo sapiens
27 GAS8  
Two-hybrid Homo sapiens
28 CSNK2A1 1457
Biochemical Activity Homo sapiens
29 DHX16 8449
Co-fractionation Homo sapiens
30 APBB1  
Reconstituted Complex Homo sapiens
31 PPP1R10  
Affinity Capture-MS Homo sapiens
32 SNRPF 6636
Two-hybrid Homo sapiens
33 NDUFS2 4720
Co-fractionation Homo sapiens
34 SFPQ 6421
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
35 ARMC7  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
36 TMA16  
Affinity Capture-MS Homo sapiens
37 KHDRBS3  
Two-hybrid Homo sapiens
38 QPRT 23475
Affinity Capture-MS Homo sapiens
39 WDR76  
Affinity Capture-MS Homo sapiens
40 RNPS1 10921
Affinity Capture-MS Homo sapiens
41 NONO 4841
Affinity Capture-MS Homo sapiens
42 B3GNT2 10678
Affinity Capture-MS Homo sapiens
43 OGDH 4967
Co-fractionation Homo sapiens
44 WWP2 11060
Affinity Capture-MS Homo sapiens
45 MRPS31  
Co-fractionation Homo sapiens
46 PFKFB2 5208
Affinity Capture-MS Homo sapiens
47 MCM2 4171
Co-fractionation Homo sapiens
48 LOC100506753  
Protein-RNA Homo sapiens
49 TAF2  
Affinity Capture-MS Homo sapiens
50 LENG1  
Two-hybrid Homo sapiens
51 Srsf9  
Two-hybrid Mus musculus
52 NUP35 129401
Proximity Label-MS Homo sapiens
53 C8orf82  
Proximity Label-MS Homo sapiens
54 SNRPC 6631
Two-hybrid Homo sapiens
55 OBSL1 23363
Affinity Capture-MS Homo sapiens
56 EWSR1 2130
Two-hybrid Homo sapiens
57 BRINP1  
Affinity Capture-MS Homo sapiens
58 KRT31 3881
Two-hybrid Homo sapiens
59 Ssbp1  
Two-hybrid Mus musculus
60 PPM1A 5494
Co-fractionation Homo sapiens
61 Taf15  
Two-hybrid Mus musculus
62 ITGA4 3676
Affinity Capture-MS Homo sapiens
63 EED  
Affinity Capture-MS Homo sapiens
64 CATSPER1  
Two-hybrid Homo sapiens
65 EXOSC8  
Two-hybrid Homo sapiens
66 VCAM1 7412
Affinity Capture-MS Homo sapiens
67 GTSE1 51512
Two-hybrid Homo sapiens
68 YTHDF3  
Two-hybrid Homo sapiens
69 MECP2 4204
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 Sf3b2  
Two-hybrid Mus musculus
71 CD2BP2 10421
Two-hybrid Homo sapiens
72 GUCD1  
Two-hybrid Homo sapiens
73 CSNK1D 1453
Affinity Capture-MS Homo sapiens
74 SERBP1 26135
Affinity Capture-MS Homo sapiens
75 FEM1A  
Affinity Capture-MS Homo sapiens
76 SOD1 6647
Affinity Capture-MS Homo sapiens
77 TFIP11  
Two-hybrid Homo sapiens
78 DVL2 1856
Two-hybrid Homo sapiens
79 KIF14 9928
Affinity Capture-MS Homo sapiens
80 SSX1  
Affinity Capture-MS Homo sapiens
81 HSPA8 3312
Affinity Capture-MS Homo sapiens
82 DMRTB1  
Two-hybrid Homo sapiens
83 PRMT1 3276
Affinity Capture-MS Homo sapiens
84 HEXIM1 10614
Affinity Capture-MS Homo sapiens
85 CHMP4C 92421
Affinity Capture-MS Homo sapiens
86 CLK2 1196
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
87 WBP4  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
88 JMJD6 23210
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 P4HA1 5033
Affinity Capture-MS Homo sapiens
90 Klc4  
Two-hybrid Mus musculus
91 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
92 CEP55 55165
Two-hybrid Homo sapiens
93 TOX4  
Affinity Capture-MS Homo sapiens
94 RPL9 6133
Co-fractionation Homo sapiens
95 UNKL  
Two-hybrid Homo sapiens
96 MEPCE 56257
Affinity Capture-MS Homo sapiens
97 CTBP1 1487
Two-hybrid Homo sapiens
98 SUPT5H 6829
Two-hybrid Homo sapiens
99 Nudt21 68219
Two-hybrid Mus musculus
100 SNRNP25  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
101 RBM7  
Two-hybrid Homo sapiens
102 FAM192A  
Affinity Capture-MS Homo sapiens
103 STAU1 6780
Affinity Capture-MS Homo sapiens
104 MICU2 221154
Affinity Capture-MS Homo sapiens
105 DDX20 11218
Affinity Capture-MS Homo sapiens
106 CHMP4B 128866
Affinity Capture-MS Homo sapiens
107 GCC1 79571
Two-hybrid Homo sapiens
108 YAP1 10413
Affinity Capture-MS Homo sapiens
109 GATA3  
Proximity Label-MS Homo sapiens
110 NTRK1 4914
Affinity Capture-MS Homo sapiens
111 SNX18 112574
Two-hybrid Homo sapiens
112 SMAD3 4088
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
113 U2AF2 11338
Co-fractionation Homo sapiens
114 RAD18  
Affinity Capture-MS Homo sapiens
115 EXOSC5 56915
Two-hybrid Homo sapiens
116 CSNK1E 1454
Affinity Capture-MS Homo sapiens
117 NSRP1  
Affinity Capture-MS Homo sapiens
118 SMAD2 4087
Affinity Capture-MS Homo sapiens
119 PRMT2  
Two-hybrid Homo sapiens
120 SRSF1 6426
Two-hybrid Homo sapiens
121 ENO1 2023
Affinity Capture-RNA Homo sapiens
122 LYAR 55646
Affinity Capture-MS Homo sapiens
123 DHX40  
Proximity Label-MS Homo sapiens
124 TEX19  
Affinity Capture-MS Homo sapiens
125 Bbs5  
Two-hybrid Mus musculus
126 MAGOH 4116
Two-hybrid Homo sapiens
127 Fubp3  
Two-hybrid Mus musculus
128 EPB41L5 57669
Affinity Capture-MS Homo sapiens
129 TRIM31  
Affinity Capture-MS Homo sapiens
130 ITCH 83737
Reconstituted Complex Homo sapiens
131 ZCCHC11 23318
Two-hybrid Homo sapiens
132 NUSAP1 51203
Affinity Capture-MS Homo sapiens
133 Cpsf6  
Two-hybrid Mus musculus
134 CEBPA  
Proximity Label-MS Homo sapiens
Protein-peptide Homo sapiens
135 Ptcd2 68927
Two-hybrid Mus musculus
136 C6orf165  
Two-hybrid Homo sapiens
137 CCNT1  
Affinity Capture-MS Homo sapiens
138 SP100 6672
Affinity Capture-MS Homo sapiens
139 RBM10  
Two-hybrid Homo sapiens
140 SRSF4 6429
Two-hybrid Homo sapiens
141 Nono 53610
Two-hybrid Mus musculus
142 PID1 55022
Two-hybrid Homo sapiens
143 ANLN 54443
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 ATXN1 6310
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
145 CBX4  
Affinity Capture-MS Homo sapiens
146 RPL23A 6147
Affinity Capture-MS Homo sapiens
147 OGT 8473
Reconstituted Complex Homo sapiens
148 FAM76B  
Affinity Capture-MS Homo sapiens
149 RPS19 6223
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
150 Grb2 14784
Two-hybrid Mus musculus
151 PRPF4B 8899
Affinity Capture-MS Homo sapiens
152 KHSRP 8570
Co-fractionation Homo sapiens
153 NR4A1  
Affinity Capture-MS Homo sapiens
154 Gnb2l1 14694
Two-hybrid Mus musculus
155 POP1 10940
Affinity Capture-MS Homo sapiens
156 YTHDF1 54915
Two-hybrid Homo sapiens
157 ECT2 1894
Affinity Capture-MS Homo sapiens
158 SNRPB 6628
Affinity Capture-MS Homo sapiens
159 CLTA 1211
Affinity Capture-MS Homo sapiens
160 CTNNB1 1499
Affinity Capture-MS Homo sapiens
161 PRKAA2 5563
Two-hybrid Homo sapiens
162 KCMF1 56888
Affinity Capture-MS Homo sapiens
163 ERGIC3 51614
Co-fractionation Homo sapiens
164 Rbm14  
Two-hybrid Mus musculus
165 Cnn3 71994
Two-hybrid Mus musculus
166 SF1 7536
Two-hybrid Homo sapiens
167 BCHE 590
Affinity Capture-MS Homo sapiens
168 DCAF13 25879
Affinity Capture-MS Homo sapiens
169 CTTN 2017
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
170 Dusp14  
Two-hybrid Mus musculus
171 DTX2 113878
Proximity Label-MS Homo sapiens
172 YY1 7528
Affinity Capture-MS Homo sapiens
173 SNRPA 6626
Affinity Capture-MS Homo sapiens
174 HNRNPA1 3178
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
175 HNRNPF 3185
Two-hybrid Homo sapiens
176 SUZ12  
Affinity Capture-MS Homo sapiens
177 NIP7 51388
Two-hybrid Homo sapiens
178 FN1 2335
Affinity Capture-MS Homo sapiens
179 NXF1 10482
Affinity Capture-RNA Homo sapiens
Two-hybrid Homo sapiens
180 MYCN  
Affinity Capture-MS Homo sapiens
181 RUNX1T1  
Two-hybrid Homo sapiens
182 PIP4K2A 5305
Affinity Capture-MS Homo sapiens
183 PCBP1 5093
Affinity Capture-MS Homo sapiens
184 TACO1  
Affinity Capture-MS Homo sapiens
185 PPIL4  
Affinity Capture-MS Homo sapiens
186 PSPC1 55269
Affinity Capture-MS Homo sapiens
187 RPA3 6119
Affinity Capture-MS Homo sapiens
188 FXR2 9513
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
189 LMNB1 4001
Affinity Capture-MS Homo sapiens
190 EMC2 9694
Affinity Capture-MS Homo sapiens
191 UBAP2L 9898
Co-fractionation Homo sapiens
192 SEC16A 9919
Affinity Capture-MS Homo sapiens
193 TOP1 7150
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
194 TNS2 23371
Two-hybrid Homo sapiens
195 FIP1L1 81608
Affinity Capture-MS Homo sapiens
196 SORBS3 10174
Two-hybrid Homo sapiens
197 PRPF40A 55660
Affinity Capture-MS Homo sapiens
198 CUL7 9820
Affinity Capture-MS Homo sapiens
199 DDRGK1 65992
Affinity Capture-MS Homo sapiens
200 Kif22  
Two-hybrid Mus musculus
201 Pef1  
Two-hybrid Mus musculus
202 CLTC 1213
Affinity Capture-MS Homo sapiens
203 Pspc1  
Two-hybrid Mus musculus
204 HINT1 3094
Two-hybrid Homo sapiens
205 GRB2 2885
Two-hybrid Homo sapiens
206 BAG4  
Two-hybrid Homo sapiens
207 Sf3a3 75062
Two-hybrid Mus musculus
208 SART1 9092
Affinity Capture-MS Homo sapiens
209 RBM14 10432
Affinity Capture-MS Homo sapiens
210 ALG13 79868
Two-hybrid Homo sapiens
211 NUDT21 11051
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
212 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
213 BCAS2 10286
Two-hybrid Homo sapiens
214 DAB2 1601
Affinity Capture-MS Homo sapiens
215 NUP133 55746
Co-fractionation Homo sapiens
216 CPSF6 11052
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
217 RBM25 58517
Affinity Capture-MS Homo sapiens
218 WWOX 51741
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
219 Eif3g 53356
Two-hybrid Mus musculus
220 SF3B4 10262
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
221 SEC23B 10483
Two-hybrid Homo sapiens
222 NUFIP2 57532
Affinity Capture-MS Homo sapiens
223 EPB41L2 2037
Affinity Capture-MS Homo sapiens
224 SLAIN1 122060
Two-hybrid Homo sapiens
225 PDHA1 5160
Affinity Capture-MS Homo sapiens
226 RBMX 27316
Co-fractionation Homo sapiens
227 Yars 107271
Two-hybrid Mus musculus
228 PTBP1 5725
Co-fractionation Homo sapiens
229 Pfn1 18643
Two-hybrid Mus musculus
230 C1orf35  
Affinity Capture-MS Homo sapiens
231 TXNL4A 10907
Two-hybrid Homo sapiens
232 ARHGAP18 93663
Affinity Capture-MS Homo sapiens
233 WDR82 80335
Affinity Capture-MS Homo sapiens
234 EIF4ENIF1 56478
Two-hybrid Homo sapiens
235 EXOSC1 51013
Two-hybrid Homo sapiens
236 SHMT2 6472
Affinity Capture-RNA Homo sapiens
237 LSM5  
Two-hybrid Homo sapiens
238 CCDC93 54520
Affinity Capture-MS Homo sapiens
239 WIF1 11197
Affinity Capture-MS Homo sapiens
240 NCK2 8440
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
241 Eif4b 75705
Two-hybrid Mus musculus
242 ESR1  
Affinity Capture-MS Homo sapiens
243 UFL1 23376
Affinity Capture-MS Homo sapiens
244 ERCC3  
Co-fractionation Homo sapiens
245 RBFOX2 23543
Two-hybrid Homo sapiens
246 LRPAP1 4043
Affinity Capture-MS Homo sapiens
247 MOV10 4343
Affinity Capture-RNA Homo sapiens
248 EZH2  
Affinity Capture-MS Homo sapiens
249 ZNF766  
Affinity Capture-MS Homo sapiens
250 CDK9 1025
Affinity Capture-MS Homo sapiens
251 MREG  
Two-hybrid Homo sapiens
252 CIT 11113
Affinity Capture-MS Homo sapiens
253 PRPF6 24148
Two-hybrid Homo sapiens
254 MFAP1  
Affinity Capture-MS Homo sapiens
255 DDX42 11325
Affinity Capture-MS Homo sapiens
256 LDLR 3949
Positive Genetic Homo sapiens
257 EIF5A 1984
Affinity Capture-MS Homo sapiens
258 SNW1 22938
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
259 C9orf72  
Affinity Capture-MS Homo sapiens
260 AR 367
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
261 RPA1 6117
Affinity Capture-MS Homo sapiens
262 METTL17  
Affinity Capture-MS Homo sapiens
263 CKAP4 10970
Affinity Capture-MS Homo sapiens
264 NDC80 10403
Affinity Capture-MS Homo sapiens
265 CLP1  
Affinity Capture-Western Homo sapiens
266 SP7  
Proximity Label-MS Homo sapiens
267 LUC7L 55692
Affinity Capture-MS Homo sapiens
268 DDX56  
Affinity Capture-MS Homo sapiens
269 EP300 2033
Affinity Capture-MS Homo sapiens
270 CDC5L 988
Affinity Capture-MS Homo sapiens
271 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here