Gene description for SNRPB
Gene name
small nuclear ribonucleoprotein polypeptides B and B1
Gene symbol
SNRPB
Other names/aliases
CCMS COD SNRPB1 Sm-B/B' SmB/B' SmB/SmB' snRNP-B
Species
Homo sapiens
Database cross references - SNRPB
ExoCarta
ExoCarta_6628
Entrez Gene
6628
HGNC
11153
MIM
182282
UniProt
P14678
SNRPB identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Prostate cancer cells
25844599
Thymus
23844026
Gene ontology annotations for SNRPB
Experiment description of studies that identified SNRPB in exosomes
1
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
275
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|RAB5A
EV Cytosolic markers
✔
CD9|CD82|CD63|CD81
EV Membrane markers
✔
AIF
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25844599
Organism
Homo sapiens
Experiment description
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors
Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name
Oncotarget
Publication year
2015
Sample
Prostate cancer cells
Sample name
DU145 - Docetaxel sensitive
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.12-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry/Flow cytometry/Western blotting
4
Experiment ID
217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23844026
Organism
Homo sapiens
Experiment description
Characterization of human thymic exosomes.
Authors
Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name
PLoS One
Publication year
2013
Sample
Thymus
Sample name
Normal-Thymus
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for SNRPB
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
SART3
9733
Affinity Capture-MS
Homo sapiens
2
HTATSF1
27336
Affinity Capture-MS
Homo sapiens
3
ASCC2
Two-hybrid
Homo sapiens
4
SMN1
6606
Invitro
Homo sapiens
5
SNRNP200
23020
Affinity Capture-MS
Homo sapiens
6
GEMIN4
50628
Affinity Capture-MS
Homo sapiens
7
EFTUD2
9343
Affinity Capture-MS
Homo sapiens
8
KHK
3795
Affinity Capture-MS
Homo sapiens
9
PSMA3
5684
Two-hybrid
Homo sapiens
10
LGALS1
3956
Affinity Capture-Western
Homo sapiens
11
TOP3B
Two-hybrid
Homo sapiens
12
COIL
Invitro
Homo sapiens
13
CTDP1
Invivo
Homo sapiens
14
DDX20
Invivo
Homo sapiens
Invitro
Homo sapiens
15
C14orf1
11161
Two-hybrid
Homo sapiens
16
DYNC1H1
1778
Affinity Capture-MS
Homo sapiens
17
PRPF8
10594
Affinity Capture-MS
Homo sapiens
18
SNRPD3
6634
Invitro
Homo sapiens
19
CLNS1A
1207
Affinity Capture-Western
Homo sapiens
20
WDR77
79084
Reconstituted Complex
Homo sapiens
View the network
image/svg+xml
Pathways in which SNRPB is involved