Gene description for SNRPB
Gene name small nuclear ribonucleoprotein polypeptides B and B1
Gene symbol SNRPB
Other names/aliases CCMS
COD
SNRPB1
Sm-B/B'
SmB/B'
SmB/SmB'
snRNP-B
Species Homo sapiens
 Database cross references - SNRPB
ExoCarta ExoCarta_6628
Vesiclepedia VP_6628
Entrez Gene 6628
HGNC 11153
MIM 182282
UniProt P14678  
 SNRPB identified in sEVs derived from the following tissue/cell type
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for SNRPB
Molecular Function
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IPI
    protein binding GO:0005515 IPI
    telomerase RNA binding GO:0070034 IPI
    snRNP binding GO:0070990 IBA
    histone pre-mRNA DCP binding GO:0071208 IEA
    U1 snRNP binding GO:1990446 IEA
    U2 snRNP binding GO:1990447 IEA
Biological Process
    spliceosomal snRNP assembly GO:0000387 IDA
    mRNA splicing, via spliceosome GO:0000398 IBA
    mRNA splicing, via spliceosome GO:0000398 IC
    mRNA splicing, via spliceosome GO:0000398 IDA
    mRNA splicing, via spliceosome GO:0000398 NAS
    protein methylation GO:0006479 IDA
    RNA splicing GO:0008380 TAS
    7-methylguanosine cap hypermethylation GO:0036261 NAS
    U2-type prespliceosome assembly GO:1903241 NAS
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleus GO:0005634 NAS
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    spliceosomal complex GO:0005681 IPI
    spliceosomal complex GO:0005681 NAS
    U5 snRNP GO:0005682 IBA
    U5 snRNP GO:0005682 NAS
    U7 snRNP GO:0005683 IDA
    U2-type spliceosomal complex GO:0005684 IDA
    U1 snRNP GO:0005685 IBA
    U1 snRNP GO:0005685 IDA
    U1 snRNP GO:0005685 IPI
    U1 snRNP GO:0005685 NAS
    U2 snRNP GO:0005686 IBA
    U2 snRNP GO:0005686 NAS
    U4 snRNP GO:0005687 IBA
    U4 snRNP GO:0005687 IDA
    U4 snRNP GO:0005687 NAS
    U12-type spliceosomal complex GO:0005689 IDA
    telomerase holoenzyme complex GO:0005697 IDA
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    small nuclear ribonucleoprotein complex GO:0030532 TAS
    methylosome GO:0034709 IDA
    SMN-Sm protein complex GO:0034719 IDA
    U4/U6 x U5 tri-snRNP complex GO:0046540 IBA
    U4/U6 x U5 tri-snRNP complex GO:0046540 IDA
    U4/U6 x U5 tri-snRNP complex GO:0046540 IPI
    U2-type prespliceosome GO:0071004 IBA
    U2-type precatalytic spliceosome GO:0071005 IDA
    U2-type catalytic step 2 spliceosome GO:0071007 IDA
    catalytic step 2 spliceosome GO:0071013 IBA
    catalytic step 2 spliceosome GO:0071013 IDA
    histone pre-mRNA 3'end processing complex GO:0071204 IEA
 Experiment description of studies that identified SNRPB in sEVs
1
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
2
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
3
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
4
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
5
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
13
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
27
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SNRPB
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PQBP1  
Affinity Capture-MS Homo sapiens
2 RBPMS 11030
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
3 SKIV2L 6499
Two-hybrid Homo sapiens
4 SRPK2 6733
Affinity Capture-MS Homo sapiens
5 TOP3B 8940
Two-hybrid Homo sapiens
6 DDX17 10521
Affinity Capture-MS Homo sapiens
7 KIF20A 10112
Affinity Capture-MS Homo sapiens
8 THOC7 80145
Affinity Capture-MS Homo sapiens
9 SCAF4 57466
Affinity Capture-MS Homo sapiens
10 RBM12 10137
Two-hybrid Homo sapiens
11 PRPF40A 55660
Affinity Capture-MS Homo sapiens
12 SOX2  
Affinity Capture-MS Homo sapiens
13 DDX23 9416
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 PRR22  
Two-hybrid Homo sapiens
15 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 SNRNP70 6625
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 CRNKL1 51340
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 GPATCH1  
Affinity Capture-MS Homo sapiens
19 KIF23 9493
Affinity Capture-MS Homo sapiens
20 ACTR3 10096
Cross-Linking-MS (XL-MS) Homo sapiens
21 USP39 10713
Affinity Capture-MS Homo sapiens
22 CPSF7 79869
Affinity Capture-MS Homo sapiens
23 OIP5  
Two-hybrid Homo sapiens
24 TFIP11  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
25 KRT31 3881
Two-hybrid Homo sapiens
26 Nhp2l1 20826
Affinity Capture-MS Mus musculus
27 SNRPD3 6634
Co-crystal Structure Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
28 HMG20B  
Co-fractionation Homo sapiens
29 POLR2C 5432
Affinity Capture-MS Homo sapiens
30 MECP2 4204
Affinity Capture-MS Homo sapiens
31 ARIH2 10425
Affinity Capture-MS Homo sapiens
32 KIF14 9928
Affinity Capture-MS Homo sapiens
33 RBMX 27316
Affinity Capture-MS Homo sapiens
34 CHMP4C 92421
Affinity Capture-MS Homo sapiens
35 WBP4  
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
36 DPP8 54878
Affinity Capture-MS Homo sapiens
37 MEPCE 56257
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 SUPT5H 6829
Affinity Capture-MS Homo sapiens
39 CSTF2 1478
Affinity Capture-MS Homo sapiens
40 C17orf85  
Affinity Capture-MS Homo sapiens
41 SNRNP25  
Affinity Capture-MS Homo sapiens
42 PPIH 10465
Affinity Capture-MS Homo sapiens
43 PLEKHB2 55041
Two-hybrid Homo sapiens
44 DDX20 11218
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 C10orf55  
Two-hybrid Homo sapiens
46 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
47 NOS2  
Affinity Capture-MS Homo sapiens
48 ASCC2 84164
Two-hybrid Homo sapiens
49 ZRSR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 CUL2 8453
Affinity Capture-MS Homo sapiens
51 SRPK3  
Affinity Capture-MS Homo sapiens
52 SON 6651
Affinity Capture-MS Homo sapiens
53 DDX39B 7919
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
54 PDCD7  
Affinity Capture-MS Homo sapiens
55 SRPK1 6732
Affinity Capture-MS Homo sapiens
56 CCDC12  
Affinity Capture-MS Homo sapiens
57 ZNF326 284695
Affinity Capture-MS Homo sapiens
58 BCLAF1 9774
Affinity Capture-MS Homo sapiens
59 DDX5 1655
Affinity Capture-MS Homo sapiens
60 HSPA5 3309
Co-fractionation Homo sapiens
61 CSTF1 1477
Affinity Capture-MS Homo sapiens
62 CD2BP2 10421
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
63 UBQLN2 29978
Two-hybrid Homo sapiens
64 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 PRR20D  
Two-hybrid Homo sapiens
66 ZC3H11A  
Affinity Capture-MS Homo sapiens
67 FN1 2335
Affinity Capture-MS Homo sapiens
68 STRAP 11171
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
69 YTHDC1  
Affinity Capture-MS Homo sapiens
70 PRMT5 10419
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 GEMIN4 50628
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 PRR20B  
Two-hybrid Homo sapiens
73 MFAP1  
Affinity Capture-MS Homo sapiens
74 RPA3 6119
Affinity Capture-MS Homo sapiens
75 LSM3 27258
Affinity Capture-MS Homo sapiens
76 GIGYF1  
Two-hybrid Homo sapiens
77 PHF5A 84844
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
78 OOEP  
Two-hybrid Homo sapiens
79 U2SURP 23350
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
80 DDX46 9879
Co-fractionation Homo sapiens
81 PAXBP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 YBX1 4904
Co-fractionation Homo sapiens
83 CHTOP  
Affinity Capture-MS Homo sapiens
84 FASN 2194
Co-fractionation Homo sapiens
85 EAPP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 CTR9 9646
Affinity Capture-MS Homo sapiens
87 BCAS2 10286
Affinity Capture-MS Homo sapiens
88 WDR77 79084
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
89 POLR2J  
Affinity Capture-MS Homo sapiens
90 MACF1 23499
Affinity Capture-MS Homo sapiens
91 RBM25 58517
Affinity Capture-MS Homo sapiens
92 SNUPN 10073
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
93 TCERG1 10915
Affinity Capture-MS Homo sapiens
94 SRSF9 8683
Affinity Capture-MS Homo sapiens
95 CWF19L2  
Affinity Capture-MS Homo sapiens
96 SMN2 6607
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
97 PUF60 22827
Co-fractionation Homo sapiens
98 TRA2B 6434
Affinity Capture-MS Homo sapiens
99 TUT1  
Affinity Capture-MS Homo sapiens
100 DYNC1H1 1778
Affinity Capture-MS Homo sapiens
101 PRAME  
Affinity Capture-MS Homo sapiens
102 WWP2 11060
Two-hybrid Homo sapiens
103 LARP7 51574
Affinity Capture-MS Homo sapiens
104 IK 3550
Affinity Capture-MS Homo sapiens
105 ALYREF 10189
Affinity Capture-MS Homo sapiens
106 HNRNPL 3191
Affinity Capture-MS Homo sapiens
107 SUPT6H 6830
Affinity Capture-MS Homo sapiens
108 PRPF4 9128
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 SNW1 22938
Affinity Capture-MS Homo sapiens
110 SNRPA1 6627
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
111 IFIT2 3433
Affinity Capture-MS Homo sapiens
112 EXOSC8  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
113 PSMD3 5709
Co-fractionation Homo sapiens
114 HNRNPH1 3187
Two-hybrid Homo sapiens
115 CCAR1 55749
Affinity Capture-MS Homo sapiens
116 NCBP1 4686
Affinity Capture-MS Homo sapiens
117 RBM22 55696
Affinity Capture-MS Homo sapiens
118 RPA2 6118
Affinity Capture-MS Homo sapiens
119 SF3B1 23451
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 ARL6IP4  
Affinity Capture-MS Homo sapiens
121 LGALS1 3956
Affinity Capture-Western Homo sapiens
122 GEMIN8 54960
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 CAND1 55832
Affinity Capture-MS Homo sapiens
124 AAR2 25980
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
125 COPA 1314
Cross-Linking-MS (XL-MS) Homo sapiens
126 SNRPF 6636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
127 SAFB 6294
Affinity Capture-MS Homo sapiens
128 RNPS1 10921
Affinity Capture-MS Homo sapiens
129 DHX35  
Affinity Capture-MS Homo sapiens
130 TLN1 7094
Co-fractionation Homo sapiens
131 PRC1 9055
Affinity Capture-MS Homo sapiens
132 SRRM2 23524
Affinity Capture-MS Homo sapiens
133 KHDRBS1 10657
Affinity Capture-MS Homo sapiens
134 OBSL1 23363
Affinity Capture-MS Homo sapiens
135 RSRC1  
Affinity Capture-MS Homo sapiens
136 TRAP1 10131
Co-fractionation Homo sapiens
137 CUL1 8454
Affinity Capture-MS Homo sapiens
138 RBM42  
Affinity Capture-MS Homo sapiens
139 PCNA 5111
Co-fractionation Homo sapiens
140 ZCRB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 LSM2 57819
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
142 PCNP 57092
Affinity Capture-MS Homo sapiens
143 SYMPK 8189
Affinity Capture-MS Homo sapiens
144 HNRNPA0 10949
Affinity Capture-MS Homo sapiens
145 PRPF8 10594
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
146 CEP55 55165
Two-hybrid Homo sapiens
147 FHL3 2275
Two-hybrid Homo sapiens
148 ACIN1 22985
Affinity Capture-MS Homo sapiens
149 SNRNP200 23020
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 KRTAP6-2  
Two-hybrid Homo sapiens
151 SNRPD1 6632
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
152 NELFE 7936
Affinity Capture-MS Homo sapiens
153 TOX4  
Affinity Capture-MS Homo sapiens
154 SCAF11  
Affinity Capture-MS Homo sapiens
155 AKAP7 9465
Affinity Capture-MS Homo sapiens
156 MAGOH 4116
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 SS18L1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
158 TXNL4A 10907
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
159 GPATCH11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 SNRPB2 6629
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
161 ZCCHC8 55596
Affinity Capture-MS Homo sapiens
162 HNRNPD 3184
Affinity Capture-MS Homo sapiens
163 SPAG8  
Two-hybrid Homo sapiens
164 PSMA3 5684
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
165 ACLY 47
Co-fractionation Homo sapiens
166 LEO1 123169
Affinity Capture-MS Homo sapiens
167 NCBP2 22916
Affinity Capture-MS Homo sapiens
168 IKZF3  
Affinity Capture-MS Homo sapiens
169 KIN  
Affinity Capture-MS Homo sapiens
170 AKAP9 10142
Two-hybrid Homo sapiens
171 POLR2E 5434
Affinity Capture-MS Homo sapiens
172 SETD2  
Affinity Capture-MS Homo sapiens
173 YLPM1 56252
Affinity Capture-MS Homo sapiens
174 USP54 159195
Two-hybrid Homo sapiens
175 EGFR 1956
Negative Genetic Homo sapiens
176 TSSC4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 HOXA1 3198
Two-hybrid Homo sapiens
178 IKZF1  
Affinity Capture-MS Homo sapiens
179 ZMAT2  
Affinity Capture-MS Homo sapiens
180 EFTUD2 9343
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 IFIT1 3434
Affinity Capture-MS Homo sapiens
182 NLRP3  
Affinity Capture-MS Homo sapiens
183 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
184 CUL7 9820
Affinity Capture-MS Homo sapiens
185 DDRGK1 65992
Affinity Capture-MS Homo sapiens
186 ADAR 103
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
187 PFDN5 5204
Two-hybrid Homo sapiens
188 HUWE1 10075
Affinity Capture-MS Homo sapiens
189 NKAP 79576
Affinity Capture-MS Homo sapiens
190 CEP290  
Cross-Linking-MS (XL-MS) Homo sapiens
191 RBM8A 9939
Affinity Capture-MS Homo sapiens
192 TOE1 114034
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 PARP1 142
Proximity Label-MS Homo sapiens
194 ILF3 3609
Affinity Capture-MS Homo sapiens
195 SF3B4 10262
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
196 PHF3  
Affinity Capture-MS Homo sapiens
197 DMRTB1  
Two-hybrid Homo sapiens
198 PRMT7  
Reconstituted Complex Homo sapiens
199 PRKRIP1 79706
Co-fractionation Homo sapiens
200 PNMA1 9240
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
201 DDX39A 10212
Affinity Capture-MS Homo sapiens
202 NCAPD2 9918
Co-fractionation Homo sapiens
203 IL7R  
Protein-RNA Homo sapiens
204 DDX42 11325
Affinity Capture-MS Homo sapiens
205 MYC  
Affinity Capture-MS Homo sapiens
206 PRMT1 3276
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
207 Smn1 20595
Affinity Capture-MS Mus musculus
208 MRPS9 64965
Affinity Capture-MS Homo sapiens
209 CUL4A 8451
Affinity Capture-MS Homo sapiens
210 RALY 22913
Affinity Capture-MS Homo sapiens
211 GCFC2  
Affinity Capture-MS Homo sapiens
212 UBE2H 7328
Affinity Capture-MS Homo sapiens
213 HNRNPC 3183
Affinity Capture-MS Homo sapiens
214 RIOK1 83732
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
215 SNRPG 6637
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
216 SNRPE 6635
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
217 DNAJC8 22826
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
218 Prpf8 192159
Affinity Capture-MS Mus musculus
219 TGS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
220 COPRS  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
221 KHK 3795
Affinity Capture-MS Homo sapiens
222 SSB 6741
Affinity Capture-MS Homo sapiens
223 RANBP3 8498
Co-fractionation Homo sapiens
224 HNRNPR 10236
Affinity Capture-MS Homo sapiens
225 PPP1R10  
Affinity Capture-MS Homo sapiens
226 RPS6KB2  
Affinity Capture-MS Homo sapiens
227 SF3B5 83443
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
228 HNRNPUL2 221092
Affinity Capture-MS Homo sapiens
229 SART3 9733
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
230 Tgs1  
Affinity Capture-MS Mus musculus
231 PPIL1 51645
Affinity Capture-MS Homo sapiens
232 ZNF638 27332
Affinity Capture-MS Homo sapiens
233 KRT40  
Two-hybrid Homo sapiens
234 MDC1  
Affinity Capture-MS Homo sapiens
235 CALCOCO2  
Two-hybrid Homo sapiens
236 SF3A2 8175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
237 Snrnp70 20637
Affinity Capture-MS Mus musculus
238 SNRNP48  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
239 SF3B3 23450
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
240 THOC1 9984
Affinity Capture-MS Homo sapiens
241 PRR20C  
Two-hybrid Homo sapiens
242 GEMIN2 8487
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
243 LIN28A  
Affinity Capture-MS Homo sapiens
244 POLR2K  
Affinity Capture-MS Homo sapiens
245 EPB41L3 23136
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
246 BANP  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
247 KRT34  
Two-hybrid Homo sapiens
248 P4HA1 5033
Affinity Capture-MS Homo sapiens
249 CUL4B 8450
Affinity Capture-MS Homo sapiens
250 PARK2  
Affinity Capture-MS Homo sapiens
251 PHAX  
Affinity Capture-MS Homo sapiens
252 CLNS1A 1207
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
253 SMEK1 55671
Affinity Capture-MS Homo sapiens
254 SKAP2 8935
Affinity Capture-MS Homo sapiens
255 GOLGA2 2801
Two-hybrid Homo sapiens
256 SRRT 51593
Affinity Capture-MS Homo sapiens
257 WDR61 80349
Affinity Capture-MS Homo sapiens
258 PPIL2  
Affinity Capture-MS Homo sapiens
259 CHMP4B 128866
Affinity Capture-MS Homo sapiens
260 FUBP1 8880
Two-hybrid Homo sapiens
261 BARD1 580
Affinity Capture-MS Homo sapiens
262 U2AF2 11338
Co-fractionation Homo sapiens
263 BAG4  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
264 SNRPN 6638
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
265 RPA4  
Proximity Label-MS Homo sapiens
266 COA7  
Two-hybrid Homo sapiens
267 DHX9 1660
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
268 NKTR  
Affinity Capture-MS Homo sapiens
269 SAFB2 9667
Affinity Capture-MS Homo sapiens
270 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
271 SF3A3 10946
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
272 POLR2B 5431
Affinity Capture-MS Homo sapiens
273 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
274 RBBP6 5930
Affinity Capture-MS Homo sapiens
275 SF3B2 10992
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
276 ZBTB2 57621
Affinity Capture-MS Homo sapiens
277 LSM8 51691
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
278 METTL14  
Affinity Capture-MS Homo sapiens
279 CHERP 10523
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
280 LSM4 25804
Affinity Capture-MS Homo sapiens
281 HTATSF1 27336
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
282 ZFR 51663
Affinity Capture-MS Homo sapiens
283 RPRD2  
Affinity Capture-MS Homo sapiens
284 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
285 POLR2A 5430
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
286 PRPF19 27339
Affinity Capture-MS Homo sapiens
287 PPWD1 23398
Affinity Capture-MS Homo sapiens
288 ZC3H18  
Affinity Capture-MS Homo sapiens
289 CAAP1  
Affinity Capture-MS Homo sapiens
290 RFX6  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
291 TOP1 7150
Cross-Linking-MS (XL-MS) Homo sapiens
292 NHP2L1 4809
Affinity Capture-MS Homo sapiens
293 DIDO1  
Affinity Capture-MS Homo sapiens
294 HSPD1 3329
Co-fractionation Homo sapiens
295 KRTAP6-3  
Two-hybrid Homo sapiens
296 RBM17 84991
Co-fractionation Homo sapiens
297 FNBP4  
Protein-peptide Homo sapiens
298 SRRM1 10250
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
299 SMN1 6606
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
300 KNTC1 9735
Cross-Linking-MS (XL-MS) Homo sapiens
301 CC2D2A  
Cross-Linking-MS (XL-MS) Homo sapiens
302 CWC27 10283
Cross-Linking-MS (XL-MS) Homo sapiens
303 CDC40  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
304 RPA1 6117
Affinity Capture-MS Homo sapiens
305 INCA1  
Two-hybrid Homo sapiens
306 SNRPA 6626
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
307 HNRNPM 4670
Affinity Capture-MS Homo sapiens
308 THRAP3 9967
Affinity Capture-MS Homo sapiens
309 UBXN11  
Two-hybrid Homo sapiens
310 THOC6 79228
Affinity Capture-MS Homo sapiens
311 CCDC97  
Affinity Capture-MS Homo sapiens
312 DDX58 23586
Affinity Capture-RNA Homo sapiens
313 RNPC3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
314 UFL1 23376
Affinity Capture-MS Homo sapiens
315 LSM7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
316 PPIG 9360
Affinity Capture-MS Homo sapiens
317 API5 8539
Affinity Capture-MS Homo sapiens
318 PRR20E  
Two-hybrid Homo sapiens
319 KRTAP19-6  
Two-hybrid Homo sapiens
320 TRIM23 373
Two-hybrid Homo sapiens
321 FLNA 2316
Co-fractionation Homo sapiens
322 METTL3  
Affinity Capture-MS Homo sapiens
323 RPRD1B 58490
Affinity Capture-MS Homo sapiens
324 MRPS22 56945
Affinity Capture-MS Homo sapiens
325 ZNF318 24149
Affinity Capture-MS Homo sapiens
326 LUC7L3 51747
Affinity Capture-MS Homo sapiens
327 CDKN2A 1029
Reconstituted Complex Homo sapiens
328 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
329 CRBN  
Affinity Capture-MS Homo sapiens
330 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
331 PARD3B 117583
Affinity Capture-MS Homo sapiens
332 POLDIP3 84271
Affinity Capture-MS Homo sapiens
333 CMTR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
334 QARS 5859
Cross-Linking-MS (XL-MS) Homo sapiens
335 COIL  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
336 KRTAP19-1  
Two-hybrid Homo sapiens
337 ANLN 54443
Affinity Capture-MS Homo sapiens
338 PPIE 10450
Affinity Capture-MS Homo sapiens
339 ZC3H14  
Affinity Capture-MS Homo sapiens
340 CTNNBL1 56259
Affinity Capture-MS Homo sapiens
341 DHX8 1659
Affinity Capture-MS Homo sapiens
342 DAB1 1600
Two-hybrid Homo sapiens
343 USP9X 8239
Affinity Capture-Western Homo sapiens
344 ZC3H4 23211
Affinity Capture-MS Homo sapiens
345 PRPF3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
346 AQR 9716
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
347 SYF2  
Affinity Capture-MS Homo sapiens
348 SNRPD2 6633
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
349 CWF19L1 55280
Affinity Capture-MS Homo sapiens
350 ILF2 3608
Affinity Capture-MS Homo sapiens
351 KIAA1429 25962
Affinity Capture-MS Homo sapiens
352 SP3  
Two-hybrid Homo sapiens
353 ISY1 57461
Affinity Capture-MS Homo sapiens
354 COPS5 10987
Affinity Capture-MS Homo sapiens
355 NCOA5  
Affinity Capture-MS Homo sapiens
356 SNRPC 6631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
357 IFIT3 3437
Affinity Capture-MS Homo sapiens
358 SUGP1  
Affinity Capture-MS Homo sapiens
359 ZGPAT  
Affinity Capture-MS Homo sapiens
360 INTS6 26512
Cross-Linking-MS (XL-MS) Homo sapiens
361 CDC73  
Affinity Capture-MS Homo sapiens
362 DDX41 51428
Affinity Capture-MS Homo sapiens
363 SLC4A1AP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
364 MYCN  
Affinity Capture-MS Homo sapiens
365 PRR20A  
Two-hybrid Homo sapiens
366 PRPF6 24148
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
367 SMU1 55234
Affinity Capture-MS Homo sapiens
368 STAU1 6780
Affinity Capture-MS Homo sapiens
369 PRPS2 5634
Affinity Capture-MS Homo sapiens
370 PTCD3 55037
Affinity Capture-MS Homo sapiens
371 SRSF4 6429
Affinity Capture-MS Homo sapiens
372 PPP1R8 5511
Affinity Capture-MS Homo sapiens
373 CYSRT1 375791
Two-hybrid Homo sapiens
374 NCS1 23413
Co-fractionation Homo sapiens
375 SF3B6 51639
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
376 PABPN1 8106
Affinity Capture-MS Homo sapiens
377 PRPF31 26121
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
378 WDR82 80335
Affinity Capture-MS Homo sapiens
379 CPSF1 29894
Affinity Capture-MS Homo sapiens
380 TAF15 8148
Affinity Capture-MS Homo sapiens
381 PRPF4B 8899
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
382 FANCD2  
Affinity Capture-MS Homo sapiens
383 SRSF7 6432
Co-fractionation Homo sapiens
384 C14orf1 11161
Two-hybrid Homo sapiens
385 SNRNP35  
Affinity Capture-MS Homo sapiens
386 PNN 5411
Affinity Capture-MS Homo sapiens
387 SNRPB 6628
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
388 PLRG1 5356
Affinity Capture-MS Homo sapiens
389 RLIM 51132
Affinity Capture-MS Homo sapiens
390 SRSF1 6426
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
391 HCFC1 3054
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
392 Rbm14  
Two-hybrid Mus musculus
393 ZNF143  
Two-hybrid Homo sapiens
394 XAB2 56949
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
395 MAGI2  
Two-hybrid Homo sapiens
396 THOC5 8563
Affinity Capture-MS Homo sapiens
397 SART1 9092
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
398 SF3A1 10291
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
399 AKAP8  
Affinity Capture-MS Homo sapiens
400 COG6 57511
Two-hybrid Homo sapiens
401 L3MBTL3  
Two-hybrid Homo sapiens
402 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
403 AKAP5  
Cross-Linking-MS (XL-MS) Homo sapiens
404 LSM11  
Affinity Capture-MS Homo sapiens
405 KRTAP6-1  
Two-hybrid Homo sapiens
406 NANOG  
Affinity Capture-MS Homo sapiens
407 FARP1 10160
Affinity Capture-MS Homo sapiens
408 ANKS1B 56899
Cross-Linking-MS (XL-MS) Homo sapiens
409 DHX15 1665
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
410 Prmt5 27374
Affinity Capture-MS Mus musculus
411 TTC33  
Affinity Capture-MS Homo sapiens
412 CPSF6 11052
Affinity Capture-MS Homo sapiens
413 ERH 2079
Affinity Capture-MS Homo sapiens
414 POLR2L 5441
Affinity Capture-MS Homo sapiens
415 GEMIN6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
416 SAP18 10284
Affinity Capture-MS Homo sapiens
417 CUL5 8065
Affinity Capture-MS Homo sapiens
418 SMNDC1  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
419 SMURF1 57154
Affinity Capture-MS Homo sapiens
420 SLC7A6OS  
Affinity Capture-MS Homo sapiens
421 ELAVL1 1994
Affinity Capture-MS Homo sapiens
422 Sf3a1 67465
Affinity Capture-MS Mus musculus
423 EIF4A3 9775
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
424 LSM5  
Affinity Capture-MS Homo sapiens
425 CWC15  
Affinity Capture-MS Homo sapiens
426 ANKAR  
Cross-Linking-MS (XL-MS) Homo sapiens
427 SNRNP40 9410
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
428 MICAL3 57553
Cross-Linking-MS (XL-MS) Homo sapiens
429 AIRE  
Affinity Capture-MS Homo sapiens
430 UPF1 5976
Affinity Capture-Western Homo sapiens
431 ZNF830  
Affinity Capture-MS Homo sapiens
432 GEMIN5 25929
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
433 LSM6 11157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
434 HNRNPU 3192
Affinity Capture-MS Homo sapiens
435 C9orf72  
Affinity Capture-MS Homo sapiens
436 MBD3L1  
Two-hybrid Homo sapiens
437 PAF1 54623
Affinity Capture-MS Homo sapiens
438 FAM168B 130074
Two-hybrid Homo sapiens
439 SERTAD3  
Two-hybrid Homo sapiens
440 CDC5L 988
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here