Gene description for PPIH
Gene name peptidylprolyl isomerase H (cyclophilin H)
Gene symbol PPIH
Other names/aliases CYP-20
CYPH
SnuCyp-20
USA-CYP
Species Homo sapiens
 Database cross references - PPIH
ExoCarta ExoCarta_10465
Entrez Gene 10465
HGNC 14651
MIM 606095
UniProt O43447  
 PPIH identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for PPIH
Molecular Function
    protein binding GO:0005515 IPI
    cyclosporin A binding GO:0016018 TAS
    ribonucleoprotein complex binding GO:0043021 IDA
    peptidyl-prolyl cis-trans isomerase activity GO:0003755 IDA
Biological Process
    protein folding GO:0006457 IEA
    mRNA splicing, via spliceosome GO:0000398 IC
    positive regulation of viral genome replication GO:0045070 IMP
    protein complex assembly GO:0006461 TAS
    protein peptidyl-prolyl isomerization GO:0000413 IBA
Subcellular Localization
    U4/U6 snRNP GO:0071001 IDA
    cytoplasm GO:0005737 IDA
    spliceosomal complex GO:0005681 IC
    U4/U6 x U5 tri-snRNP complex GO:0046540 IDA
    nuclear speck GO:0016607 IDA
 Experiment description of studies that identified PPIH in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PPIH
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PRPF4 9128
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PPIH is involved
No pathways found





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