Gene description for RBM39
Gene name RNA binding motif protein 39
Gene symbol RBM39
Other names/aliases CAPER
CAPERalpha
FSAP59
HCC1
RNPC2
Species Homo sapiens
 Database cross references - RBM39
ExoCarta ExoCarta_9584
Vesiclepedia VP_9584
Entrez Gene 9584
HGNC 15923
MIM 604739
UniProt Q14498  
 RBM39 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for RBM39
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    RS domain binding GO:0050733 IEA
    U1 snRNP binding GO:1990446 IBA
Biological Process
    RNA processing GO:0006396 TAS
    mRNA processing GO:0006397 IEA
    RNA splicing GO:0008380 IEA
    regulation of mRNA splicing, via spliceosome GO:0048024 IDA
    regulation of mRNA splicing, via spliceosome GO:0048024 IMP
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    microtubule cytoskeleton GO:0015630 IDA
    nuclear speck GO:0016607 IDA
    nuclear speck GO:0016607 IMP
    protein-containing complex GO:0032991 IMP
    centriolar satellite GO:0034451 IDA
 Experiment description of studies that identified RBM39 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
23
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RBM39
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPL27 6155
Affinity Capture-MS Homo sapiens
2 PQBP1  
Affinity Capture-MS Homo sapiens
3 TRMT1L 81627
Affinity Capture-MS Homo sapiens
4 PRPF8 10594
Affinity Capture-MS Homo sapiens
5 RIN3  
Affinity Capture-MS Homo sapiens
6 SRPK2 6733
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
7 TRIM26 7726
Affinity Capture-MS Homo sapiens
8 UBC 7316
Affinity Capture-MS Homo sapiens
9 CSNK2A1 1457
Two-hybrid Homo sapiens
10 PRPF40A 55660
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
11 UQCRFS1 7386
Affinity Capture-MS Homo sapiens
12 SEPT2 4735
Co-fractionation Homo sapiens
13 PCBP3 54039
Affinity Capture-MS Homo sapiens
14 DDX23 9416
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 WDR76  
Affinity Capture-MS Homo sapiens
16 CRNKL1 51340
Affinity Capture-MS Homo sapiens
17 GPATCH1  
Co-fractionation Homo sapiens
18 UBE2O 63893
Affinity Capture-MS Homo sapiens
19 SF3B1 23451
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 PPP3CB  
Affinity Capture-MS Homo sapiens
21 BHLHA15  
Affinity Capture-MS Homo sapiens
22 TFIP11  
Affinity Capture-MS Homo sapiens
23 ARHGAP19  
Affinity Capture-MS Homo sapiens
24 SNRPD3 6634
Affinity Capture-MS Homo sapiens
25 POLR2C 5432
Affinity Capture-MS Homo sapiens
26 SFN 2810
Affinity Capture-MS Homo sapiens
27 MECP2 4204
Affinity Capture-MS Homo sapiens
28 ARIH2 10425
Affinity Capture-MS Homo sapiens
29 BUD31 8896
Affinity Capture-MS Homo sapiens
30 RPS11 6205
Affinity Capture-MS Homo sapiens
31 SREK1 140890
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
32 RPL19 6143
Affinity Capture-MS Homo sapiens
33 RBM14 10432
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
34 NINL  
Proximity Label-MS Homo sapiens
35 RBMX 27316
Affinity Capture-MS Homo sapiens
36 MTCH2 23788
Affinity Capture-MS Homo sapiens
37 UTP14A 10813
Co-fractionation Homo sapiens
38 C17orf85  
Affinity Capture-MS Homo sapiens
39 PPIH 10465
Affinity Capture-MS Homo sapiens
40 DDX20 11218
Affinity Capture-MS Homo sapiens
41 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 OGT 8473
Reconstituted Complex Homo sapiens
43 RPL31 6160
Affinity Capture-MS Homo sapiens
44 LAP3 51056
Affinity Capture-MS Homo sapiens
45 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
46 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
47 NOB1  
Affinity Capture-MS Homo sapiens
48 SRPK3  
Affinity Capture-MS Homo sapiens
49 SON 6651
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
50 DDX39B 7919
Affinity Capture-MS Homo sapiens
51 SND1 27044
Affinity Capture-MS Homo sapiens
52 GTPBP4 23560
Affinity Capture-MS Homo sapiens
53 SRPK1 6732
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
54 SP100 6672
Two-hybrid Homo sapiens
55 CCDC12  
Affinity Capture-MS Homo sapiens
56 ZNF326 284695
Affinity Capture-MS Homo sapiens
57 BCLAF1 9774
Affinity Capture-MS Homo sapiens
58 STK3 6788
Affinity Capture-MS Homo sapiens
59 SUGP1  
Affinity Capture-MS Homo sapiens
60 DAP3 7818
Affinity Capture-MS Homo sapiens
61 SIRT7  
Affinity Capture-MS Homo sapiens
62 CD2BP2 10421
Affinity Capture-MS Homo sapiens
63 IFI16 3428
Affinity Capture-MS Homo sapiens
64 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 MTNR1A  
Two-hybrid Homo sapiens
66 THOC7 80145
Affinity Capture-MS Homo sapiens
67 EIF2S2 8894
Affinity Capture-MS Homo sapiens
68 ZC3H11A  
Affinity Capture-MS Homo sapiens
69 GEMIN4 50628
Affinity Capture-MS Homo sapiens
70 PCBP1 5093
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 MFAP1  
Affinity Capture-MS Homo sapiens
72 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
73 LTV1  
Affinity Capture-MS Homo sapiens
74 PHF5A 84844
Affinity Capture-MS Homo sapiens
75 HSPA1A 3303
Cross-Linking-MS (XL-MS) Homo sapiens
76 STMN1 3925
Cross-Linking-MS (XL-MS) Homo sapiens
77 RPS16 6217
Affinity Capture-MS Homo sapiens
78 WDR77 79084
Affinity Capture-MS Homo sapiens
79 PAXBP1  
Affinity Capture-MS Homo sapiens
80 BCAS2 10286
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
81 AK8  
Two-hybrid Homo sapiens
82 CHTOP  
Affinity Capture-MS Homo sapiens
83 RRS1 23212
Co-fractionation Homo sapiens
84 RBM25 58517
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
85 WWOX 51741
Affinity Capture-MS Homo sapiens
86 TCERG1 10915
Affinity Capture-MS Homo sapiens
87 SRSF9 8683
Affinity Capture-MS Homo sapiens
88 PNISR  
Co-fractionation Homo sapiens
89 TRMT112 51504
Co-fractionation Homo sapiens
90 TRA2B 6434
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 RPS15A 6210
Affinity Capture-MS Homo sapiens
92 RPL10A 4736
Affinity Capture-MS Homo sapiens
93 DARS-AS1  
Protein-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
94 RPS24 6229
Affinity Capture-MS Homo sapiens
95 NCL 4691
Affinity Capture-MS Homo sapiens
96 ALYREF 10189
Affinity Capture-MS Homo sapiens
97 HNRNPL 3191
Affinity Capture-MS Homo sapiens
98 ARHGAP36  
Affinity Capture-MS Homo sapiens
99 SNRNP70 6625
Co-fractionation Homo sapiens
100 PRPF4 9128
Affinity Capture-MS Homo sapiens
101 RPL23A 6147
Affinity Capture-MS Homo sapiens
102 SNRPA1 6627
Affinity Capture-MS Homo sapiens
103 SEC61A1 29927
Affinity Capture-MS Homo sapiens
104 CCAR1 55749
Affinity Capture-MS Homo sapiens
105 NCBP1 4686
Affinity Capture-MS Homo sapiens
106 SPRTN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 BCKDK 10295
Affinity Capture-MS Homo sapiens
108 ZBTB22  
Two-hybrid Homo sapiens
109 RBM22 55696
Affinity Capture-MS Homo sapiens
110 EIF2S3 1968
Affinity Capture-MS Homo sapiens
111 EIF3K 27335
Affinity Capture-MS Homo sapiens
112 KCTD10 83892
Affinity Capture-MS Homo sapiens
113 TARDBP 23435
Affinity Capture-MS Homo sapiens
114 RPA2 6118
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
115 PRPF38A 84950
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
116 USP39 10713
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
117 ARL6IP4  
Two-hybrid Homo sapiens
118 CHCHD1  
Affinity Capture-MS Homo sapiens
119 RPL14 9045
Affinity Capture-MS Homo sapiens
120 CAND1 55832
Affinity Capture-MS Homo sapiens
121 SNRPF 6636
Affinity Capture-MS Homo sapiens
122 RPS3 6188
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 RPS18 6222
Affinity Capture-MS Homo sapiens
124 RNPS1 10921
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
125 B3GNT2 10678
Affinity Capture-MS Homo sapiens
126 RRP12 23223
Affinity Capture-MS Homo sapiens
127 CCDC14  
Proximity Label-MS Homo sapiens
128 MRPS23 51649
Affinity Capture-MS Homo sapiens
129 SRRM2 23524
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 OBSL1 23363
Affinity Capture-MS Homo sapiens
131 MRPS7 51081
Affinity Capture-MS Homo sapiens
132 TRIM25 7706
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
133 CUL1 8454
Affinity Capture-MS Homo sapiens
134 RBM42  
Affinity Capture-MS Homo sapiens
135 SDCBP 6386
Two-hybrid Homo sapiens
136 RRP7A 27341
Co-fractionation Homo sapiens
137 LSM2 57819
Affinity Capture-MS Homo sapiens
138 JMJD6 23210
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 HNRNPA0 10949
Affinity Capture-MS Homo sapiens
140 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
141 DDX21 9188
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
142 ACIN1 22985
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
143 SNRNP200 23020
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 SNRPD1 6632
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 RPL38 6169
Affinity Capture-MS Homo sapiens
146 LUC7L2 51631
Affinity Capture-MS Homo sapiens
147 MAGOH 4116
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
148 RPLP0 6175
Affinity Capture-MS Homo sapiens
149 TXNL4A 10907
Affinity Capture-MS Homo sapiens
150 GPATCH11  
Affinity Capture-MS Homo sapiens
151 EIF4B 1975
Cross-Linking-MS (XL-MS) Homo sapiens
152 SNRPB2 6629
Affinity Capture-MS Homo sapiens
153 SGPL1 8879
Affinity Capture-MS Homo sapiens
154 C11orf57  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
155 RPS2 6187
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 MRPS35 60488
Affinity Capture-MS Homo sapiens
157 RC3H2  
Affinity Capture-MS Homo sapiens
158 MRPS11  
Affinity Capture-MS Homo sapiens
159 POLR2E 5434
Affinity Capture-MS Homo sapiens
160 POLK  
Affinity Capture-MS Homo sapiens
161 SETD2  
Affinity Capture-MS Homo sapiens
162 YLPM1 56252
Affinity Capture-MS Homo sapiens
163 TNPO3 23534
Affinity Capture-MS Homo sapiens
164 ZMAT2  
Affinity Capture-MS Homo sapiens
165 UBL5 59286
Affinity Capture-MS Homo sapiens
166 EFTUD2 9343
Affinity Capture-MS Homo sapiens
167 TADA2A  
Affinity Capture-MS Homo sapiens
168 MYC  
Affinity Capture-MS Homo sapiens
169 EGFR 1956
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
170 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
171 THOC1 9984
Affinity Capture-MS Homo sapiens
172 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
173 SNW1 22938
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
174 DDRGK1 65992
Affinity Capture-MS Homo sapiens
175 FYTTD1  
Affinity Capture-MS Homo sapiens
176 MRPS17 51373
Affinity Capture-MS Homo sapiens
177 ADAR 103
Affinity Capture-MS Homo sapiens
178 EIF3H 8667
Affinity Capture-MS Homo sapiens
179 RPL13 6137
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
180 PSMB10 5699
Affinity Capture-MS Homo sapiens
181 HNRNPH2 3188
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
182 TOE1 114034
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
183 FAM200A  
Two-hybrid Homo sapiens
184 ILF3 3609
Co-fractionation Homo sapiens
185 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 FOLR1 2348
Affinity Capture-MS Homo sapiens
187 SF3B4 10262
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
188 RPS12 6206
Affinity Capture-MS Homo sapiens
189 RPS4X 6191
Affinity Capture-MS Homo sapiens
190 MRPS15  
Affinity Capture-MS Homo sapiens
191 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
192 KHDRBS2  
Affinity Capture-MS Homo sapiens
193 Arhgap6  
Affinity Capture-MS Mus musculus
194 EIF3J 8669
Affinity Capture-MS Homo sapiens
195 EIF3M 10480
Affinity Capture-MS Homo sapiens
196 RPSA 3921
Affinity Capture-MS Homo sapiens
197 YBX3 8531
Affinity Capture-MS Homo sapiens
198 TCF3  
Affinity Capture-MS Homo sapiens
199 BANP  
Two-hybrid Homo sapiens
200 DDX42 11325
Affinity Capture-MS Homo sapiens
201 RPS29 6235
Affinity Capture-MS Homo sapiens
202 PHC2  
Two-hybrid Homo sapiens
203 PRMT1 3276
Affinity Capture-MS Homo sapiens
204 MRPS9 64965
Affinity Capture-MS Homo sapiens
205 RALY 22913
Co-fractionation Homo sapiens
206 MRPS27 23107
Affinity Capture-MS Homo sapiens
207 UBE2H 7328
Affinity Capture-MS Homo sapiens
208 HNRNPC 3183
Affinity Capture-MS Homo sapiens
209 FOXC1  
Affinity Capture-MS Homo sapiens
210 INO80B 83444
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
211 DNAJC8 22826
Affinity Capture-MS Homo sapiens
212 MME 4311
Affinity Capture-MS Homo sapiens
213 REL 5966
Two-hybrid Homo sapiens
214 RPS19 6223
Affinity Capture-MS Homo sapiens
215 BYSL 705
Affinity Capture-MS Homo sapiens
216 PGR  
Reconstituted Complex Homo sapiens
217 HNRNPR 10236
Affinity Capture-MS Homo sapiens
218 PPP1R10  
Affinity Capture-MS Homo sapiens
219 SF3B5 83443
Affinity Capture-MS Homo sapiens
220 HNRNPUL2 221092
Affinity Capture-MS Homo sapiens
221 CUL7 9820
Affinity Capture-MS Homo sapiens
222 PLEKHG4  
Affinity Capture-MS Homo sapiens
223 Kcnk1  
Affinity Capture-MS Mus musculus
224 CDK12 51755
Affinity Capture-MS Homo sapiens
225 MDC1  
Affinity Capture-MS Homo sapiens
226 SF3A2 8175
Affinity Capture-MS Homo sapiens
227 MRS2  
Affinity Capture-MS Homo sapiens
228 ATRX 546
Affinity Capture-MS Homo sapiens
229 TFCP2 7024
Affinity Capture-MS Homo sapiens
230 CSNK2B 1460
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
231 RBM8A 9939
Affinity Capture-MS Homo sapiens
232 LIN28A  
Affinity Capture-MS Homo sapiens
233 PSME3 10197
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
234 VTN 7448
Co-fractionation Homo sapiens
235 CLK2 1196
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
236 PNO1 56902
Affinity Capture-MS Homo sapiens
237 P4HA1 5033
Affinity Capture-MS Homo sapiens
238 RPL9 6133
Affinity Capture-MS Homo sapiens
239 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
240 PPIL1 51645
Affinity Capture-MS Homo sapiens
241 GOLGA2 2801
Two-hybrid Homo sapiens
242 SRRT 51593
Affinity Capture-MS Homo sapiens
243 ACACA 31
Negative Genetic Homo sapiens
244 POU6F2  
Two-hybrid Homo sapiens
245 SAFB2 9667
Affinity Capture-MS Homo sapiens
246 RAN 5901
Co-fractionation Homo sapiens
247 NTRK1 4914
Affinity Capture-MS Homo sapiens
248 U2AF2 11338
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
249 RPLP1 6176
Affinity Capture-MS Homo sapiens
250 DHX9 1660
Affinity Capture-MS Homo sapiens
251 POLR2B 5431
Affinity Capture-MS Homo sapiens
252 NKAP 79576
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
253 NKTR  
Affinity Capture-MS Homo sapiens
254 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
255 HDAC5 10014
Affinity Capture-MS Homo sapiens
256 SF3A3 10946
Affinity Capture-MS Homo sapiens
257 BARD1 580
Affinity Capture-MS Homo sapiens
258 PCBP2 5094
Affinity Capture-MS Homo sapiens
259 LARP1 23367
Affinity Capture-MS Homo sapiens
260 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
261 SF3B2 10992
Affinity Capture-MS Homo sapiens
262 PREX1  
Affinity Capture-MS Homo sapiens
263 RP9P  
Two-hybrid Homo sapiens
264 CHERP 10523
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
265 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
266 DHX30 22907
Affinity Capture-MS Homo sapiens
267 Ect2  
Affinity Capture-MS Mus musculus
268 THAP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
269 NCBP2 22916
Affinity Capture-MS Homo sapiens
270 MRPS28  
Affinity Capture-MS Homo sapiens
271 PRPF19 27339
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
272 RPS13 6207
Affinity Capture-MS Homo sapiens
273 ZC3H18  
Affinity Capture-MS Homo sapiens
274 CAAP1  
Affinity Capture-MS Homo sapiens
275 SEC16A 9919
Affinity Capture-MS Homo sapiens
276 RPS14 6208
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
277 TOP1 7150
Co-fractionation Homo sapiens
278 NHP2L1 4809
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
279 RPL22 6146
Affinity Capture-MS Homo sapiens
280 RPL18 6141
Affinity Capture-MS Homo sapiens
281 RNF2  
Affinity Capture-MS Homo sapiens
282 SEPT7 989
Co-fractionation Homo sapiens
283 TSR1 55720
Affinity Capture-MS Homo sapiens
284 HDGF 3068
Affinity Capture-MS Homo sapiens
285 XRCC5 7520
Affinity Capture-MS Homo sapiens
286 AHSA1 10598
Affinity Capture-MS Homo sapiens
287 SUGT1 10910
Affinity Capture-MS Homo sapiens
288 FNBP4  
Affinity Capture-MS Homo sapiens
289 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
290 PHB2 11331
Proximity Label-MS Homo sapiens
291 KIAA0907  
Two-hybrid Homo sapiens
292 RPS25 6230
Affinity Capture-MS Homo sapiens
293 FBXL6  
Affinity Capture-MS Homo sapiens
294 SEC61G 23480
Affinity Capture-MS Homo sapiens
295 HOMEZ  
Two-hybrid Homo sapiens
296 CDC40  
Affinity Capture-MS Homo sapiens
297 DDX3X 1654
Co-fractionation Homo sapiens
298 RPA1 6117
Affinity Capture-MS Homo sapiens
299 THRAP3 9967
Affinity Capture-MS Homo sapiens
300 HSPB1 3315
Two-hybrid Homo sapiens
301 MRPS10 55173
Affinity Capture-MS Homo sapiens
302 S100A9 6280
Co-fractionation Homo sapiens
303 RPL34 6164
Affinity Capture-MS Homo sapiens
304 UFL1 23376
Affinity Capture-MS Homo sapiens
305 PPIG 9360
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
306 MRPS18B 28973
Affinity Capture-MS Homo sapiens
307 FLNA 2316
Co-fractionation Homo sapiens
308 RPS7 6201
Affinity Capture-MS Homo sapiens
309 RPS27L 51065
Affinity Capture-MS Homo sapiens
310 ARHGAP24  
Affinity Capture-MS Homo sapiens
311 RC3H1 149041
Affinity Capture-MS Homo sapiens
312 MRPS22 56945
Affinity Capture-MS Homo sapiens
313 EP300 2033
Affinity Capture-MS Homo sapiens
314 CRBN  
Affinity Capture-MS Homo sapiens
315 RIT1 6016
Negative Genetic Homo sapiens
316 RPS3A 6189
Affinity Capture-MS Homo sapiens
317 RPL30 6156
Affinity Capture-MS Homo sapiens
318 PPIE 10450
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
319 ARHGEF26 26084
Affinity Capture-MS Homo sapiens
320 FAM192A  
Affinity Capture-MS Homo sapiens
321 RPL13A 23521
Affinity Capture-MS Homo sapiens
322 ZC3H14  
Affinity Capture-MS Homo sapiens
323 CTNNBL1 56259
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
324 RPL10 6134
Affinity Capture-MS Homo sapiens
325 LSM4 25804
Affinity Capture-MS Homo sapiens
326 PRPF3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
327 DVL3 1857
Two-hybrid Homo sapiens
328 AQR 9716
Affinity Capture-MS Homo sapiens
329 CCDC124 115098
Affinity Capture-MS Homo sapiens
330 SNRPD2 6633
Affinity Capture-MS Homo sapiens
331 APP 351
Reconstituted Complex Homo sapiens
332 RPS20 6224
Affinity Capture-MS Homo sapiens
333 DYRK1A 1859
Affinity Capture-MS Homo sapiens
334 ISY1 57461
Affinity Capture-MS Homo sapiens
335 COPS5 10987
Affinity Capture-MS Homo sapiens
336 FBXW7  
Affinity Capture-MS Homo sapiens
337 RPL24 6152
Affinity Capture-MS Homo sapiens
338 MRPS24 64951
Affinity Capture-MS Homo sapiens
339 RPS8 6202
Affinity Capture-MS Homo sapiens
340 MRPS26 64949
Affinity Capture-MS Homo sapiens
341 EED  
Affinity Capture-MS Homo sapiens
342 NR2C1  
Affinity Capture-MS Homo sapiens
343 NAP1L4 4676
Affinity Capture-MS Homo sapiens
344 SLC4A1AP  
Affinity Capture-MS Homo sapiens
345 MYCN  
Affinity Capture-MS Homo sapiens
346 SSR3 6747
Affinity Capture-MS Homo sapiens
347 RPS26 6231
Affinity Capture-MS Homo sapiens
348 E2F4  
Affinity Capture-MS Homo sapiens
349 RPS23 6228
Affinity Capture-MS Homo sapiens
350 GEMIN5 25929
Affinity Capture-MS Homo sapiens
351 RBM23  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
352 MRPS34 65993
Affinity Capture-MS Homo sapiens
353 IRF2BPL 64207
Affinity Capture-MS Homo sapiens
354 SMU1 55234
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
355 STAU1 6780
Affinity Capture-MS Homo sapiens
356 SRSF6 6431
Affinity Capture-MS Homo sapiens
357 PTCD3 55037
Affinity Capture-MS Homo sapiens
358 PPP1R8 5511
Affinity Capture-MS Homo sapiens
359 DDX5 1655
Affinity Capture-MS Homo sapiens
360 KMT2E  
Affinity Capture-MS Homo sapiens
361 MLX  
Two-hybrid Homo sapiens
362 SF3B6 51639
Affinity Capture-MS Homo sapiens
363 RPL27A 6157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
364 PABPN1 8106
Affinity Capture-MS Homo sapiens
365 PRPF31 26121
Affinity Capture-MS Homo sapiens
366 CEBPA  
Protein-peptide Homo sapiens
367 ARHGAP20  
Affinity Capture-MS Homo sapiens
368 KRTAP12-2  
Two-hybrid Homo sapiens
369 WDR82 80335
Affinity Capture-MS Homo sapiens
370 SRSF11 9295
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
371 PRPF4B 8899
Affinity Capture-MS Homo sapiens
372 RPLP2 6181
Affinity Capture-MS Homo sapiens
373 SRSF7 6432
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
374 ZCCHC10  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
375 PNN 5411
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
376 RPL35 11224
Affinity Capture-MS Homo sapiens
377 PLRG1 5356
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
378 CTNNB1 1499
Affinity Capture-MS Homo sapiens
379 SRSF1 6426
Affinity Capture-MS Homo sapiens
380 SRRM4  
Two-hybrid Homo sapiens
381 SAP30BP  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
382 XAB2 56949
Affinity Capture-MS Homo sapiens
383 RPL3 6122
Affinity Capture-MS Homo sapiens
384 THOC5 8563
Affinity Capture-MS Homo sapiens
385 NAP1L1 4673
Affinity Capture-MS Homo sapiens
386 RPL7 6129
Affinity Capture-MS Homo sapiens
387 SUZ12  
Affinity Capture-MS Homo sapiens
388 SART1 9092
Affinity Capture-MS Homo sapiens
389 NXF1 10482
Affinity Capture-RNA Homo sapiens
390 SF3A1 10291
Affinity Capture-MS Homo sapiens
391 JUN 3725
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
392 RBM14-RBM4 100526737
Co-fractionation Homo sapiens
393 N4BP2L2 10443
Affinity Capture-MS Homo sapiens
394 SF3B3 23450
Affinity Capture-MS Homo sapiens
395 KRAS 3845
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
396 BMP4 652
Affinity Capture-MS Homo sapiens
397 GNB2L1 10399
Affinity Capture-MS Homo sapiens
398 RNF113A 7737
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
399 DHX15 1665
Affinity Capture-MS Homo sapiens
400 ESR2  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
401 SIRT6  
Affinity Capture-MS Homo sapiens
402 BKRF1  
Affinity Capture-MS
403 TTC33  
Affinity Capture-MS Homo sapiens
404 SRRM1 10250
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
405 ERH 2079
Affinity Capture-MS Homo sapiens
406 ZNF746  
Affinity Capture-MS Homo sapiens
407 MRPS31  
Affinity Capture-MS Homo sapiens
408 SAP18 10284
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
409 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
410 TTC14  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
411 SMNDC1  
Affinity Capture-MS Homo sapiens
412 ELAVL1 1994
Affinity Capture-MS Homo sapiens
413 Sf3a1 67465
Affinity Capture-MS Mus musculus
414 EIF4A3 9775
Affinity Capture-MS Homo sapiens
415 CWC15  
Affinity Capture-MS Homo sapiens
416 RPS28 6234
Affinity Capture-MS Homo sapiens
417 SNRNP40 9410
Affinity Capture-MS Homo sapiens
418 EZH2  
Affinity Capture-MS Homo sapiens
419 SREK1IP1  
Two-hybrid Homo sapiens
420 CDK9 1025
Affinity Capture-MS Homo sapiens
421 PINK1  
Affinity Capture-MS Homo sapiens
422 RPS6 6194
Affinity Capture-MS Homo sapiens
423 PRPF6 24148
Affinity Capture-MS Homo sapiens
424 GRSF1 2926
Proximity Label-MS Homo sapiens
425 XRCC6 2547
Affinity Capture-MS Homo sapiens
426 LSM6 11157
Affinity Capture-MS Homo sapiens
427 HNRNPU 3192
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
428 C9orf72  
Affinity Capture-MS Homo sapiens
429 IRF2BP2  
Affinity Capture-MS Homo sapiens
430 PCNP 57092
Affinity Capture-MS Homo sapiens
431 CDC5L 988
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
432 PPWD1 23398
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here