Gene description for DAP3
Gene name death associated protein 3
Gene symbol DAP3
Other names/aliases DAP-3
MRP-S29
MRPS29
bMRP-10
Species Homo sapiens
 Database cross references - DAP3
ExoCarta ExoCarta_7818
Vesiclepedia VP_7818
Entrez Gene 7818
HGNC 2673
MIM 602074
UniProt P51398  
 DAP3 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for DAP3
Molecular Function
    RNA binding GO:0003723 HDA
    structural constituent of ribosome GO:0003735 IBA
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IEA
Biological Process
    mitochondrial translation GO:0032543 NAS
    apoptotic signaling pathway GO:0097190 TAS
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial inner membrane GO:0005743 TAS
    mitochondrial small ribosomal subunit GO:0005763 IBA
    mitochondrial small ribosomal subunit GO:0005763 ISS
    mitochondrial small ribosomal subunit GO:0005763 NAS
 Experiment description of studies that identified DAP3 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for DAP3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 MRPS27 23107
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 SLIRP 81892
Proximity Label-MS Homo sapiens
4 METTL17  
Proximity Label-MS Homo sapiens
5 HIF1A 3091
Reconstituted Complex Homo sapiens
6 ZNF346  
Affinity Capture-MS Homo sapiens
7 RBMS3  
Affinity Capture-MS Homo sapiens
8 ZNF324B  
Affinity Capture-MS Homo sapiens
9 C9orf78 51759
Affinity Capture-MS Homo sapiens
10 TARDBP 23435
Affinity Capture-MS Homo sapiens
11 LHX2  
Proximity Label-MS Homo sapiens
12 RPL26 6154
Affinity Capture-MS Homo sapiens
13 TRUB2  
Proximity Label-MS Homo sapiens
14 MTG2  
Proximity Label-MS Homo sapiens
15 MAGEA1  
Affinity Capture-MS Homo sapiens
16 RPL10 6134
Affinity Capture-MS Homo sapiens
17 CHCHD1  
Proximity Label-MS Homo sapiens
18 HNRNPD 3184
Affinity Capture-MS Homo sapiens
19 UBC 7316
Affinity Capture-MS Homo sapiens
20 PYCR1 5831
Affinity Capture-MS Homo sapiens
21 PGR  
Reconstituted Complex Homo sapiens
22 RPUSD4 84881
Proximity Label-MS Homo sapiens
23 DNAJC15  
Proximity Label-MS Homo sapiens
24 MTRF1  
Proximity Label-MS Homo sapiens
25 GFM2 84340
Proximity Label-MS Homo sapiens
26 MRPS24 64951
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 CCDC90B  
Proximity Label-MS Homo sapiens
28 H1FNT  
Affinity Capture-MS Homo sapiens
29 LRPPRC 10128
Proximity Label-MS Homo sapiens
30 CAPZB 832
Affinity Capture-MS Homo sapiens
31 RPL4 6124
Affinity Capture-MS Homo sapiens
32 SNRNP70 6625
Affinity Capture-MS Homo sapiens
33 ZBTB2 57621
Affinity Capture-MS Homo sapiens
34 MCU 90550
Proximity Label-MS Homo sapiens
35 CRYZ 1429
Proximity Label-MS Homo sapiens
36 ZNF408  
Affinity Capture-MS Homo sapiens
37 RBM3 5935
Affinity Capture-MS Homo sapiens
38 PMPCA 23203
Proximity Label-MS Homo sapiens
39 HINT2 84681
Proximity Label-MS Homo sapiens
40 ZNF485  
Affinity Capture-MS Homo sapiens
41 MRPS23 51649
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 MRPS5 64969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
43 FBXW7  
Affinity Capture-MS Homo sapiens
44 C8orf82  
Proximity Label-MS Homo sapiens
45 DUSP11  
Affinity Capture-MS Homo sapiens
46 BHLHA15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 ZNF460  
Affinity Capture-MS Homo sapiens
48 DDRGK1 65992
Affinity Capture-MS Homo sapiens
49 KLF15  
Affinity Capture-MS Homo sapiens
50 DDX58 23586
Affinity Capture-RNA Homo sapiens
51 RPS9 6203
Affinity Capture-MS Homo sapiens
52 MRPS26 64949
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 SURF1  
Proximity Label-MS Homo sapiens
54 ADARB1 104
Affinity Capture-MS Homo sapiens
55 EXD2  
Proximity Label-MS Homo sapiens
56 ERAL1  
Affinity Capture-MS Homo sapiens
57 KLF4  
Affinity Capture-MS Homo sapiens
58 E4F1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 MRPS7 51081
Affinity Capture-MS Homo sapiens
60 MECP2 4204
Affinity Capture-MS Homo sapiens
61 TLX3  
Proximity Label-MS Homo sapiens
62 BTRC 8945
Affinity Capture-MS Homo sapiens
63 PMPCB 9512
Proximity Label-MS Homo sapiens
64 TACO1  
Proximity Label-MS Homo sapiens
65 FASTKD2  
Proximity Label-MS Homo sapiens
66 MTIF2 4528
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 AMOT  
Affinity Capture-MS Homo sapiens
68 FAM120A 23196
Affinity Capture-MS Homo sapiens
69 MTERF3  
Proximity Label-MS Homo sapiens
70 CTCF  
Affinity Capture-MS Homo sapiens
71 Tmed10 68581
Affinity Capture-MS Mus musculus
72 WDFY2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 LIN28A  
Affinity Capture-MS Homo sapiens
74 MDH2 4191
Proximity Label-MS Homo sapiens
75 SRSF6 6431
Affinity Capture-MS Homo sapiens
76 KLF16  
Affinity Capture-MS Homo sapiens
77 CHMP4C 92421
Affinity Capture-MS Homo sapiens
78 HAUS2  
Affinity Capture-MS Homo sapiens
79 DLD 1738
Affinity Capture-MS Homo sapiens
80 C6orf203  
Proximity Label-MS Homo sapiens
81 ZNF133  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 COX15 1355
Proximity Label-MS Homo sapiens
83 FASTKD5  
Proximity Label-MS Homo sapiens
84 ZNF17  
Affinity Capture-MS Homo sapiens
85 MCAT 27349
Affinity Capture-MS Homo sapiens
86 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 MRPS34 65993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 ZBTB47  
Affinity Capture-MS Homo sapiens
89 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 MBNL1 4154
Affinity Capture-MS Homo sapiens
91 TUFM 7284
Proximity Label-MS Homo sapiens
92 ZBTB48  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 POC1A  
Affinity Capture-MS Homo sapiens
94 PTCD3 55037
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
95 HSCB 150274
Proximity Label-MS Homo sapiens
96 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
97 RPL35 11224
Affinity Capture-MS Homo sapiens
98 SP7  
Proximity Label-MS Homo sapiens
99 SP110  
Affinity Capture-MS Homo sapiens
100 RPA2 6118
Proximity Label-MS Homo sapiens
101 VCP 7415
Affinity Capture-MS Homo sapiens
102 NTRK1 4914
Affinity Capture-MS Homo sapiens
103 FGF8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 MRPS6  
Affinity Capture-MS Homo sapiens
105 U2AF2 11338
Affinity Capture-MS Homo sapiens
106 RAD18  
Affinity Capture-MS Homo sapiens
107 GFM1 85476
Proximity Label-MS Homo sapiens
108 GLI4  
Affinity Capture-MS Homo sapiens
109 MTFMT  
Proximity Label-MS Homo sapiens
110 MRPL11 65003
Proximity Label-MS Homo sapiens
111 MTRF1L  
Proximity Label-MS Homo sapiens
112 DNAJC30  
Proximity Label-MS Homo sapiens
113 Bub1  
Affinity Capture-MS Mus musculus
114 TMEM70  
Proximity Label-MS Homo sapiens
115 MRPS14  
Affinity Capture-MS Homo sapiens
116 GLTSCR2  
Affinity Capture-MS Homo sapiens
117 TNFRSF10A 8797
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
118 MRPL2 51069
Affinity Capture-MS Homo sapiens
119 SP100 6672
Affinity Capture-MS Homo sapiens
120 COX4I1 1327
Proximity Label-MS Homo sapiens
121 CNBP 7555
Affinity Capture-MS Homo sapiens
122 CCDC59  
Affinity Capture-MS Homo sapiens
123 TLX2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 NGRN  
Proximity Label-MS Homo sapiens
125 STOML2 30968
Co-fractionation Homo sapiens
126 OTC 5009
Proximity Label-MS Homo sapiens
127 RBM39 9584
Affinity Capture-MS Homo sapiens
128 PNMA6A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 DNAJC21  
Affinity Capture-MS Homo sapiens
130 MRRF  
Proximity Label-MS Homo sapiens
131 ABT1 29777
Affinity Capture-MS Homo sapiens
132 MRPS12  
Proximity Label-MS Homo sapiens
133 AURKAIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 DAP3 7818
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
135 RPL13 6137
Affinity Capture-MS Homo sapiens
136 MRPS35 60488
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 RC3H2  
Affinity Capture-MS Homo sapiens
138 YBX1 4904
Affinity Capture-MS Homo sapiens
139 MRPS11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 MTIF3  
Proximity Label-MS Homo sapiens
141 SRSF4 6429
Affinity Capture-MS Homo sapiens
142 SRSF5 6430
Affinity Capture-MS Homo sapiens
143 CCDC109B 55013
Proximity Label-MS Homo sapiens
144 SURF6  
Affinity Capture-MS Homo sapiens
145 CUL3 8452
Affinity Capture-MS Homo sapiens
146 NR3C1 2908
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
147 RMND1 55005
Proximity Label-MS Homo sapiens
148 ZEB1  
Affinity Capture-MS Homo sapiens
149 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 DHX30 22907
Proximity Label-MS Homo sapiens
151 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
152 THRA  
Reconstituted Complex Homo sapiens
153 MRPS28  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
154 ZNF777  
Affinity Capture-MS Homo sapiens
155 C12orf65  
Proximity Label-MS Homo sapiens
156 MYCN  
Affinity Capture-MS Homo sapiens
157 CEP250 11190
Affinity Capture-MS Homo sapiens
158 CBX6  
Affinity Capture-MS Homo sapiens
159 CSNK1D 1453
Affinity Capture-MS Homo sapiens
160 MTG1  
Proximity Label-MS Homo sapiens
161 YME1L1 10730
Co-fractionation Homo sapiens
162 MYC  
Affinity Capture-MS Homo sapiens
163 RPA3 6119
Proximity Label-MS Homo sapiens
164 PPARA  
Reconstituted Complex Homo sapiens
165 COL4A5  
Affinity Capture-MS Homo sapiens
166 AHR 196
Reconstituted Complex Homo sapiens
167 TSFM 10102
Proximity Label-MS Homo sapiens
168 ACAD9 28976
Proximity Label-MS Homo sapiens
169 DYRK2 8445
Affinity Capture-MS Homo sapiens
170 VWA8 23078
Proximity Label-MS Homo sapiens
171 CLPB 81570
Proximity Label-MS Homo sapiens
172 Nedd1  
Affinity Capture-MS Mus musculus
173 MRPS17 51373
Affinity Capture-MS Homo sapiens
174 HSPA9 3313
Proximity Label-MS Homo sapiens
175 PPM1G 5496
Affinity Capture-MS Homo sapiens
176 METTL15  
Proximity Label-MS Homo sapiens
177 ZC3H3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
178 MCUR1 63933
Proximity Label-MS Homo sapiens
179 RBMS2 5939
Affinity Capture-MS Homo sapiens
180 SOX2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 AR 367
Reconstituted Complex Homo sapiens
182 RPL19 6143
Affinity Capture-MS Homo sapiens
183 ZNF574  
Affinity Capture-MS Homo sapiens
184 DNAJC4  
Proximity Label-MS Homo sapiens
185 CLPP 8192
Proximity Label-MS Homo sapiens
186 DNAJC28  
Proximity Label-MS Homo sapiens
187 CS 1431
Proximity Label-MS Homo sapiens
188 ZNF707  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
189 FADD 8772
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
190 FBXW11  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
191 ZNF331  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
192 AUH 549
Proximity Label-MS Homo sapiens
193 AMOTL1 154810
Affinity Capture-MS Homo sapiens
194 TBRG4 9238
Proximity Label-MS Homo sapiens
195 TNFRSF25  
Reconstituted Complex Homo sapiens
196 DNAJC19 131118
Proximity Label-MS Homo sapiens
197 RPL6 6128
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 MRPS2 51116
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
199 RRS1 23212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
200 LYST 1130
Affinity Capture-MS Homo sapiens
201 PRR3  
Affinity Capture-MS Homo sapiens
202 ICT1 3396
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
203 SOX15  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
204 APOBEC3D  
Affinity Capture-MS Homo sapiens
205 ZNF746  
Affinity Capture-MS Homo sapiens
206 SRP14 6727
Affinity Capture-MS Homo sapiens
207 Tsc1  
Affinity Capture-MS Mus musculus
208 MRPS31  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
209 LSM14A 26065
Affinity Capture-MS Homo sapiens
210 COX5A 9377
Co-fractionation Homo sapiens
211 DNAJA3 9093
Proximity Label-MS Homo sapiens
212 SMURF1 57154
Affinity Capture-MS Homo sapiens
213 MRPS15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
214 MRPS10 55173
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
215 HSP90AA1 3320
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
216 H2AFB3  
Affinity Capture-MS Homo sapiens
217 MRPS18C  
Affinity Capture-MS Homo sapiens
218 C21orf33  
Proximity Label-MS