Gene description for OTC
Gene name	ornithine carbamoyltransferase
Gene symbol	OTC
Other names/aliases	OCTD
Species	Homo sapiens
Database cross references - OTC
ExoCarta	ExoCarta_5009
Entrez Gene	5009
HGNC	8512
MIM	300461
UniProt	P00480
OTC identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for OTC

Molecular Function     ornithine carbamoyltransferase activity GO:0004585 IDA     amino acid binding GO:0016597 IEA     phospholipid binding GO:0005543 IEA     phosphate ion binding GO:0042301 IEA Biological Process     citrulline biosynthetic process GO:0019240 IDA     response to insulin GO:0032868 IEA     midgut development GO:0007494 IEA     ornithine catabolic process GO:0006593 IDA     small molecule metabolic process GO:0044281 TAS     ammonia homeostasis GO:0097272 IMP     cellular nitrogen compound metabolic process GO:0034641 TAS     liver development GO:0001889 IEA     response to drug GO:0042493 IEA     arginine biosynthetic process via ornithine GO:0042450 IBA     protein homotrimerization GO:0070207 IEA     response to zinc ion GO:0010043 IEA     urea cycle GO:0000050 TAS     response to biotin GO:0070781 IEA Subcellular Localization     mitochondrion GO:0005739 IDA     cytoplasm GO:0005737 IBA     mitochondrial inner membrane GO:0005743 IEA     mitochondrial matrix GO:0005759 TAS