Gene description for UQCC1
Gene name ubiquinol-cytochrome c reductase complex assembly factor 1
Gene symbol UQCC1
Other names/aliases BFZB
C20orf44
CBP3
UQCC
Species Homo sapiens
 Database cross references - UQCC1
ExoCarta ExoCarta_55245
Vesiclepedia VP_55245
Entrez Gene 55245
HGNC 15891
MIM 611797
UniProt Q9NVA1  
 UQCC1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for UQCC1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    mitochondrial respiratory chain complex III assembly GO:0034551 IBA
    mitochondrial respiratory chain complex III assembly GO:0034551 IDA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrial inner membrane GO:0005743 IDA
    cytoplasmic vesicle GO:0031410 IEA
 Experiment description of studies that identified UQCC1 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for UQCC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 AP2S1 1175
Affinity Capture-MS Homo sapiens
2 BIRC6 57448
Affinity Capture-MS Homo sapiens
3 LINGO2  
Affinity Capture-MS Homo sapiens
4 OXLD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 TRUB2  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
6 NGRN  
Proximity Label-MS Homo sapiens
7 MRPL10 124995
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 NDUFA4 4697
Affinity Capture-MS Homo sapiens
9 SRSF2 6427
Affinity Capture-MS Homo sapiens
10 MILR1  
Affinity Capture-MS Homo sapiens
11 THSD4 79875
Affinity Capture-MS Homo sapiens
12 COX20  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 FGFR3 2261
Affinity Capture-MS Homo sapiens
14 MRPS18C  
Affinity Capture-MS Homo sapiens
15 ACAD9 28976
Proximity Label-MS Homo sapiens
16 ITGA7 3679
Affinity Capture-MS Homo sapiens
17 PMPCA 23203
Proximity Label-MS Homo sapiens
18 CHODL 140578
Affinity Capture-MS Homo sapiens
19 YARS2  
Affinity Capture-MS Homo sapiens
20 FGFR4 2264
Affinity Capture-MS Homo sapiens
21 FTSJ2 29960
Affinity Capture-MS Homo sapiens
22 MRPS26 64949
Proximity Label-MS Homo sapiens
23 SUN2 25777
Affinity Capture-MS Homo sapiens
24 LRRC46  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 P3H1 64175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 UQCC2  
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
27 MTERF3  
Proximity Label-MS Homo sapiens
28 UNC45A 55898
Affinity Capture-MS Homo sapiens
29 C6orf203  
Proximity Label-MS Homo sapiens
30 FASTKD5  
Proximity Label-MS Homo sapiens
31 POLR3K  
Affinity Capture-MS Homo sapiens
32 LRIG2  
Affinity Capture-MS Homo sapiens
33 FADS1 3992
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 TUFM 7284
Proximity Label-MS Homo sapiens
35 C12orf49  
Negative Genetic Homo sapiens
36 BRCA2 675
Reconstituted Complex Homo sapiens
37 SLC5A4  
Affinity Capture-MS Homo sapiens
38 PBXIP1 57326
Affinity Capture-MS Homo sapiens
39 SLX1A  
Affinity Capture-MS Homo sapiens
40 NRBF2  
Affinity Capture-MS Homo sapiens
41 MIA3 375056
Affinity Capture-MS Homo sapiens
42 CSNK1E 1454
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 MRPL11 65003
Proximity Label-MS Homo sapiens
44 MTRF1L  
Proximity Label-MS Homo sapiens
45 TMEM131  
Affinity Capture-MS Homo sapiens
46 CERCAM 51148
Affinity Capture-MS Homo sapiens
47 CDIPT 10423
Affinity Capture-MS Homo sapiens
48 MRM1  
Affinity Capture-MS Homo sapiens
49 OTC 5009
Proximity Label-MS Homo sapiens
50 CXCR4 7852
Affinity Capture-MS Homo sapiens
51 MAN2B2 23324
Affinity Capture-MS Homo sapiens
52 MTIF2 4528
Proximity Label-MS Homo sapiens
53 NDUFA13 51079
Affinity Capture-MS Homo sapiens
54 ADAMTS7  
Affinity Capture-MS Homo sapiens
55 ECHDC2 55268
Affinity Capture-MS Homo sapiens
56 SBF1 6305
Affinity Capture-MS Homo sapiens
57 LPAR1 1902
Affinity Capture-MS Homo sapiens
58 MGRN1 23295
Affinity Capture-MS Homo sapiens
59 HAPLN3 145864
Affinity Capture-MS Homo sapiens
60 SLAIN2  
Affinity Capture-MS Homo sapiens
61 CMTM5  
Affinity Capture-MS Homo sapiens
62 TM2D2 83877
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 AUH 549
Proximity Label-MS Homo sapiens
64 JUNB  
Affinity Capture-MS Homo sapiens
65 SYS1  
Affinity Capture-MS Homo sapiens
66 POGLUT1 56983
Affinity Capture-MS Homo sapiens
67 MRPL38  
Affinity Capture-MS Homo sapiens
68 CDH13 1012
Affinity Capture-MS Homo sapiens
69 TTC13  
Affinity Capture-MS Homo sapiens
70 HVCN1 84329
Affinity Capture-MS Homo sapiens
71 CLPP 8192
Affinity Capture-MS Homo sapiens
72 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
73 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
74 TSFM 10102
Proximity Label-MS Homo sapiens
75 TMEM9 252839
Affinity Capture-MS Homo sapiens
76 C3AR1  
Affinity Capture-MS Homo sapiens
77 RNF31 55072
Affinity Capture-MS Homo sapiens
78 LRPPRC 10128
Proximity Label-MS Homo sapiens
79 ARF5 381
Affinity Capture-MS Homo sapiens
80 PNPLA1 285848
Affinity Capture-MS Homo sapiens
81 PDHA1 5160
Proximity Label-MS Homo sapiens
82 COX8A  
Proximity Label-MS Homo sapiens
83 C21orf33  
Proximity Label-MS Homo sapiens
84 EDEM2  
Affinity Capture-MS Homo sapiens
85 SEMA3B 7869
Affinity Capture-MS Homo sapiens
86 CLMN  
Affinity Capture-MS Homo sapiens
87 FUT11 170384
Affinity Capture-MS Homo sapiens
88 TBRG4 9238
Proximity Label-MS Homo sapiens
89 AARS2  
Proximity Label-MS Homo sapiens
90 FGFR1OP2  
Affinity Capture-MS Homo sapiens
91 CLSTN3 9746
Affinity Capture-MS Homo sapiens
92 FECH 2235
Affinity Capture-MS Homo sapiens
93 CDR2  
Affinity Capture-MS Homo sapiens
94 C1QBP 708
Proximity Label-MS Homo sapiens
95 METTL17  
Proximity Label-MS Homo sapiens
View the network image/svg+xml



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