Gene description for FGFR4
Gene name	fibroblast growth factor receptor 4
Gene symbol	FGFR4
Other names/aliases	CD334 JTK2 TKF
Species	Homo sapiens
Database cross references - FGFR4
ExoCarta	ExoCarta_2264
Entrez Gene	2264
HGNC	3691
MIM	134935
UniProt	P22455
FGFR4 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for FGFR4

Molecular Function     heparin binding GO:0008201 IDA     fibroblast growth factor binding GO:0017134 IPI     fibroblast growth factor-activated receptor activity GO:0005007 IGI     protein tyrosine kinase activity GO:0004713 TAS     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA Biological Process     response to bile acid GO:1903412 IMP     peptidyl-tyrosine phosphorylation GO:0018108 IDA     positive regulation of DNA biosynthetic process GO:2000573 IMP     insulin receptor signaling pathway GO:0008286 TAS     positive regulation of proteolysis GO:0045862 IMP     alveolar secondary septum development GO:0061144 IEA     epidermal growth factor receptor signaling pathway GO:0007173 TAS     positive regulation of cell proliferation GO:0008284 IGI     glucose homeostasis GO:0042593 ISS     phosphate ion homeostasis GO:0055062 ISS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     Fc-epsilon receptor signaling pathway GO:0038095 TAS     cell migration GO:0016477 IMP     positive regulation of metalloenzyme activity GO:0048554 IMP     regulation of extracellular matrix disassembly GO:0010715 IMP     fibroblast growth factor receptor signaling pathway GO:0008543 TAS     organ induction GO:0001759 IEA     protein autophosphorylation GO:0046777 IDA     phosphatidylinositol-mediated signaling GO:0048015 TAS     regulation of cholesterol homeostasis GO:2000188 ISS     regulation of lipid metabolic process GO:0019216 ISS     positive regulation of ERK1 and ERK2 cascade GO:0070374 IMP     innate immune response GO:0045087 TAS     regulation of bile acid biosynthetic process GO:0070857 IMP     positive regulation of gene expression GO:0010628 IMP Subcellular Localization     endosome GO:0005768 IEA     nucleoplasm GO:0005654 IDA     Golgi apparatus GO:0005794 IDA     cytoplasm GO:0005737 IDA     transport vesicle GO:0030133 IDA     plasma membrane GO:0005886 TAS     integral component of plasma membrane GO:0005887 IDA     endoplasmic reticulum GO:0005783 IDA     extracellular region GO:0005576 IEA     cell-cell junction GO:0005911 IDA