Gene description for PRTN3
Gene name	proteinase 3
Gene symbol	PRTN3
Other names/aliases	ACPA AGP7 C-ANCA CANCA MBN MBT NP-4 NP4 P29 PR-3 PR3
Species	Homo sapiens
Database cross references - PRTN3
ExoCarta	ExoCarta_5657
Vesiclepedia	VP_5657
Entrez Gene	5657
HGNC	9495
MIM	177020
UniProt	P24158
PRTN3 identified in exosomes derived from the following tissue/cell type
Urine	19056867

Gene ontology annotations for PRTN3

Molecular Function     serine-type endopeptidase activity GO:0004252 EXP     serine-type endopeptidase activity GO:0004252 IBA     serine-type endopeptidase activity GO:0004252 IDA     serine-type endopeptidase activity GO:0004252 IMP     signaling receptor binding GO:0005102 IPI     protein binding GO:0005515 IPI     serine-type peptidase activity GO:0008236 TAS     enzyme binding GO:0019899 IPI Biological Process     proteolysis GO:0006508 IBA     proteolysis GO:0006508 IDA     proteolysis GO:0006508 IMP     membrane protein ectodomain proteolysis GO:0006509 IMP     positive regulation of cell population proliferation GO:0008284 TAS     antimicrobial humoral response GO:0019730 TAS     collagen catabolic process GO:0030574 IEA     positive regulation of GTPase activity GO:0043547 IMP     cell-cell junction maintenance GO:0045217 IMP     negative regulation of phagocytosis GO:0050765 IDA     neutrophil extravasation GO:0072672 IMP     mature conventional dendritic cell differentiation GO:0097029 IDA Subcellular Localization     extracellular region GO:0005576 TAS     extracellular space GO:0005615 HDA     extracellular space GO:0005615 IBA     cytosol GO:0005829 IDA     cytosol GO:0005829 TAS     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     azurophil granule lumen GO:0035578 IDA     azurophil granule lumen GO:0035578 TAS     intracellular membrane-bounded organelle GO:0043231 IDA     plasma membrane raft GO:0044853 IDA     collagen-containing extracellular matrix GO:0062023 HDA     extracellular exosome GO:0070062 HDA