Experiment description of studies that identified RHBDD1 in exosomes

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for RHBDD1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 OR2M7   Affinity Capture-MS Homo sapiens 2 ITGB1 3688 Proximity Label-MS Homo sapiens 3 COPG2 26958 Proximity Label-MS Homo sapiens 4 ARHGAP1 392 Proximity Label-MS Homo sapiens 5 ANKLE2 23141 Proximity Label-MS Homo sapiens 6 BMH2   Affinity Capture-MS 7 ATL1 51062 Proximity Label-MS Homo sapiens 8 CHRNA4   Affinity Capture-MS Homo sapiens 9 RXFP1   Affinity Capture-MS Homo sapiens 10 OR10H2   Affinity Capture-MS Homo sapiens 11 PQLC1   Two-hybrid Homo sapiens 12 PCDHGB5 56101 Affinity Capture-MS Homo sapiens 13 NRSN1   Affinity Capture-MS Homo sapiens 14 ARL6IP5 10550 Proximity Label-MS Homo sapiens 15 DAPK1 1612 Reconstituted Complex Homo sapiens 16 TPTE2   Affinity Capture-MS Homo sapiens 17 FBXO25   Biochemical Activity Homo sapiens 18 ARSE 415 Affinity Capture-MS Homo sapiens 19 CD2AP 23607 Proximity Label-MS Homo sapiens 20 BSCL2   Affinity Capture-MS Homo sapiens 21 SRPR 6734 Proximity Label-MS Homo sapiens 22 STIM2 57620 Proximity Label-MS Homo sapiens 23 OR6M1   Affinity Capture-MS Homo sapiens 24 PTPN1 5770 Proximity Label-MS Homo sapiens 25 RTN4 57142 Proximity Label-MS Homo sapiens 26 TMPO 7112 Proximity Label-MS Homo sapiens 27 GABRG2   Affinity Capture-MS Homo sapiens 28 PIGN 23556 Affinity Capture-MS Homo sapiens 29 TEX264 51368 Proximity Label-MS Homo sapiens 30 CORO1B 57175 Proximity Label-MS Homo sapiens 31 RNF5   Affinity Capture-MS Homo sapiens 32 CTLA4   Affinity Capture-MS Homo sapiens 33 SF3B1 23451 Proximity Label-MS Homo sapiens 34 NUP153 9972 Proximity Label-MS Homo sapiens 35 FAM8A1 51439 Affinity Capture-MS Homo sapiens 36 TOR1AIP1 26092 Proximity Label-MS Homo sapiens 37 YIPF3 25844 Affinity Capture-MS Homo sapiens 38 STBD1 8987 Proximity Label-MS Homo sapiens 39 BTNL8   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 40 PGRMC2 10424 Proximity Label-MS Homo sapiens 41 TACSTD2 4070 Affinity Capture-MS Homo sapiens 42 CCDC47 57003 Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens 43 MTDH 92140 Proximity Label-MS Homo sapiens 44 TMEM63C   Affinity Capture-MS Homo sapiens 45 ESYT2 57488 Proximity Label-MS Homo sapiens 46 TMEM136   Affinity Capture-MS Homo sapiens 47 VAPA 9218 Proximity Label-MS Homo sapiens 48 PDLIM1 9124 Proximity Label-MS Homo sapiens 49 CAMLG 819 Proximity Label-MS Homo sapiens 50 BAZ1B 9031 Proximity Label-MS Homo sapiens 51 PALD1 27143 Proximity Label-MS Homo sapiens 52 EPB41L3 23136 Proximity Label-MS Homo sapiens 53 DHCR7 1717 Proximity Label-MS Homo sapiens 54 HTR3C   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 55 MANSC1 54682 Affinity Capture-MS Homo sapiens 56 OR5H1   Affinity Capture-MS Homo sapiens 57 EMD 2010 Proximity Label-MS Homo sapiens 58 TMX1 81542 Proximity Label-MS Homo sapiens 59 OR4N2   Affinity Capture-MS Homo sapiens 60 XRN1 54464 Proximity Label-MS Homo sapiens 61 C2CD2 25966 Proximity Label-MS Homo sapiens 62 EFHD2 79180 Proximity Label-MS Homo sapiens 63 PLEKHB2 55041 Two-hybrid Homo sapiens 64 OR2W3   Affinity Capture-MS Homo sapiens 65 ABCB5   Affinity Capture-MS Homo sapiens 66 CLCC1 23155 Proximity Label-MS Homo sapiens 67 VCP 7415 Co-crystal Structure Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 68 KCNA6   Affinity Capture-MS Homo sapiens 69 JPH1 56704 Proximity Label-MS Homo sapiens 70 PREB 10113 Proximity Label-MS Homo sapiens 71 TMX4 56255 Proximity Label-MS Homo sapiens 72 STX5 6811 Proximity Label-MS Homo sapiens 73 GYPC 2995 Two-hybrid Homo sapiens 74 NDC1 55706 Proximity Label-MS Homo sapiens 75 ACBD3 64746 Proximity Label-MS Homo sapiens 76 COX4I1 1327 Affinity Capture-MS Homo sapiens 77 LARP1 23367 Proximity Label-MS Homo sapiens 78 BCLAF1 9774 Proximity Label-MS Homo sapiens 79 FAM189B   Affinity Capture-MS Homo sapiens 80 RHBDD1 84236 Proximity Label-MS Homo sapiens Proximity Label-MS Homo sapiens 81 TMED9 54732 Affinity Capture-MS Homo sapiens 82 AGPAT6 137964 Proximity Label-MS Homo sapiens 83 VAPB 9217 Proximity Label-MS Homo sapiens 84 TIPRL 261726 Proximity Label-MS Homo sapiens 85 LRRC59 55379 Proximity Label-MS Homo sapiens 86 AHNAK 79026 Proximity Label-MS Homo sapiens 87 YLPM1 56252 Proximity Label-MS Homo sapiens 88 CISD2 493856 Proximity Label-MS Homo sapiens 89 BCAP31 10134 Proximity Label-MS Homo sapiens 90 CYB5R3 1727 Proximity Label-MS Homo sapiens 91 STIM1 6786 Proximity Label-MS Homo sapiens 92 CTTN 2017 Proximity Label-MS Homo sapiens 93 SLK 9748 Proximity Label-MS Homo sapiens 94 PI4K2A 55361 Affinity Capture-MS Homo sapiens 95 EHBP1 23301 Proximity Label-MS Homo sapiens 96 SEC24A 10802 Proximity Label-MS Homo sapiens 97 FUT3 2525 Affinity Capture-MS Homo sapiens 98 NOX1   Affinity Capture-MS Homo sapiens 99 CHRNB4   Affinity Capture-MS Homo sapiens 100 PCDH10 57575 Affinity Capture-MS Homo sapiens 101 SEC16A 9919 Proximity Label-MS Homo sapiens 102 STT3B 201595 Proximity Label-MS Homo sapiens 103 VRK2 7444 Proximity Label-MS Homo sapiens 104 FNDC3A 22862 Proximity Label-MS Homo sapiens 105 IP6K1 9807 Proximity Label-MS Homo sapiens 106 RRBP1 6238 Proximity Label-MS Homo sapiens 107 KTN1 3895 Proximity Label-MS Homo sapiens 108 ZC3HAV1 56829 Proximity Label-MS Homo sapiens 109 CSDE1 7812 Proximity Label-MS Homo sapiens 110 RNF185   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 111 SLC17A8   Affinity Capture-MS Homo sapiens 112 KCNA5   Affinity Capture-MS Homo sapiens 113 ACBD5 91452 Proximity Label-MS Homo sapiens 114 UBE2J1 51465 Proximity Label-MS Homo sapiens 115 SEC24B 10427 Proximity Label-MS Homo sapiens 116 MFHAS1 9258 Reconstituted Complex Homo sapiens 117 ALDH3A2 224 Proximity Label-MS Homo sapiens 118 USE1 55850 Proximity Label-MS Homo sapiens 119 PRRC2A 7916 Proximity Label-MS Homo sapiens 120 KCNA2   Affinity Capture-MS Homo sapiens 121 KDELR1 10945 Affinity Capture-MS Homo sapiens 122 UBXN4 23190 Proximity Label-MS Homo sapiens 123 RAB3GAP2 25782 Proximity Label-MS Homo sapiens 124 SEC23IP 11196 Proximity Label-MS Homo sapiens 125 TOR1AIP2 163590 Proximity Label-MS Homo sapiens 126 LDLRAD1   Affinity Capture-MS Homo sapiens 127 WWOX 51741 Proximity Label-MS Homo sapiens 128 EMC7 56851 Proximity Label-MS Homo sapiens 129 KCNC4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 130 EDEM1   Affinity Capture-MS Homo sapiens 131 THRAP3 9967 Proximity Label-MS Homo sapiens 132 NSDHL 50814 Proximity Label-MS Homo sapiens 133 OR2G6   Affinity Capture-MS Homo sapiens 134 MMGT1 93380 Proximity Label-MS Homo sapiens 135 PDZD8 118987 Proximity Label-MS Homo sapiens 136 AUP1 550 Proximity Label-MS Homo sapiens 137 RABL3 285282 Proximity Label-MS Homo sapiens 138 PDLIM5 10611 Proximity Label-MS Homo sapiens 139 BMH1   Affinity Capture-MS 140 LRRK2 120892 Reconstituted Complex Homo sapiens 141 SLC33A1 9197 Proximity Label-MS Homo sapiens 142 ACSL3 2181 Proximity Label-MS Homo sapiens 143 YKT6 10652 Proximity Label-MS Homo sapiens 144 IGF2R 3482 Proximity Label-MS Homo sapiens 145 TMC4   Affinity Capture-MS Homo sapiens 146 FAM189A2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 147 MARCH4   Affinity Capture-MS Homo sapiens 148 DNAJC1 64215 Proximity Label-MS Homo sapiens 149 TMEM31   Affinity Capture-MS Homo sapiens 150 CKAP4 10970 Proximity Label-MS Homo sapiens 151 VANGL1 81839 Proximity Label-MS Homo sapiens 152 CHRNB1   Affinity Capture-MS Homo sapiens 153 SEC63 11231 Proximity Label-MS Homo sapiens 154 ESYT1 23344 Proximity Label-MS Homo sapiens 155 DDRGK1 65992 Proximity Label-MS Homo sapiens 156 B3GNT8   Affinity Capture-MS Homo sapiens 157 RANBP2 5903 Proximity Label-MS Homo sapiens 158 SNAP29 9342 Proximity Label-MS Homo sapiens 159 EIF5 1983 Proximity Label-MS Homo sapiens 160 MCOLN2   Affinity Capture-MS Homo sapiens View the network

Pathways in which RHBDD1 is involved

No pathways found