Gene description for ITGAM
Gene name	integrin, alpha M (complement component 3 receptor 3 subunit)
Gene symbol	ITGAM
Other names/aliases	CD11B CR3A MAC-1 MAC1A MO1A SLEB6
Species	Homo sapiens
Database cross references - ITGAM
ExoCarta	ExoCarta_3684
Entrez Gene	3684
HGNC	6149
MIM	120980
UniProt	P11215
ITGAM identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for ITGAM

Molecular Function     heparin binding GO:0008201 IEA     protein heterodimerization activity GO:0046982 IEA     opsonin binding GO:0001846 IEA     protein binding GO:0005515 IPI     glycoprotein binding GO:0001948 IPI     heparan sulfate proteoglycan binding GO:0043395 IEA     metal ion binding GO:0046872 IEA Biological Process     activated T cell proliferation GO:0050798 IEA     blood coagulation GO:0007596 TAS     cellular extravasation GO:0045123 IEA     innate immune response GO:0045087 TAS     leukocyte migration GO:0050900 TAS     microglia development GO:0014005 IEA     leukocyte migration involved in inflammatory response GO:0002523 IEA     integrin-mediated signaling pathway GO:0007229 IEA     toll-like receptor signaling pathway GO:0002224 TAS     cell adhesion GO:0007155 TAS     toll-like receptor 4 signaling pathway GO:0034142 TAS     neutrophil chemotaxis GO:0030593 IEA     extracellular matrix organization GO:0030198 TAS     ectodermal cell differentiation GO:0010668 IEP Subcellular Localization     extracellular exosome GO:0070062 IDA     cell surface GO:0009986 IDA     plasma membrane GO:0005886 TAS     integrin complex GO:0008305 IEA     external side of plasma membrane GO:0009897 IEA     nucleus GO:0005634 IEA